For research use only. Not for use in humans.

Setrusumab (Anti-SOST / Sclerostin)

Synonyms: BPS 804 Cat.No.A2690 Purity:99%

Setrusumab (Anti-SOST / Sclerostin) is a fully humanized monoclonal antibody directed against sclerostin. Setrusumab effectively improves bone strength and has the potential to be used in the research of Osteogenesis Imperfecta (OI). MW :143.44 kD.

Quality Control

Batch: A269001 Purity: 99% Protein concentration: 7.19mg/ml Endotoxin Level: ＜1EU/mg

Cited in Nature Medicine for its top-tier quality
COA
SDS
Datasheet

Featured Inhibitors	Y-27632 Dihydrochloride SB431542 CHIR-99021 (Laduviglusib) RMC-7977 RMC-6236 (Daraxonrasib) MRTX1133 MG132 Z-VAD-FMK VT3989 IAG933

Mechanism of Action

Description	Setrusumab (Anti-SOST / Sclerostin) is a fully humanized monoclonal antibody directed against sclerostin. Setrusumab effectively improves bone strength and has the potential to be used in the research of Osteogenesis Imperfecta (OI). MW :143.44 kD.
References	[1] https://pubmed.ncbi.nlm.nih.gov/30965315/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	1847394-95-9
Molecular Weight	143.44
Isotype	Human IgG2SA
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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