For research use only. Not for use in humans.

Setrusumab (Anti-SOST / Sclerostin)

Synonyms: BPS 804 Cat.No.A2690

Setrusumab (Anti-SOST / Sclerostin) is a fully humanized monoclonal antibody directed against sclerostin. Setrusumab effectively improves bone strength and has the potential to be used in the research of Osteogenesis Imperfecta (OI). MW :143.44 kD.

Quality Control

Cited in Nature Medicine for its top-tier quality
SDS
Datasheet

Mechanism of Action

Description	Setrusumab (Anti-SOST / Sclerostin) is a fully humanized monoclonal antibody directed against sclerostin. Setrusumab effectively improves bone strength and has the potential to be used in the research of Osteogenesis Imperfecta (OI). MW :143.44 kD.
References	[1] https://pubmed.ncbi.nlm.nih.gov/30965315/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	1847394-95-9
Molecular Weight	143.44
Isotype	Human IgG2SA
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.