Home Metabolism -Cell Cycle Serine/threonin kinase WNK Selective Inhibitors

WNK Selective Inhibitors

  • serine/threonine kinase
  • STK
  • WNK
  • DCLK
  • GCN
  • GAK
  • SRPK
  • PASK
  • BUB1
Catalog No. Product Name Information Selective / Pan IC50 / Ki
S8358 WNK463 WNK463 is a pan-WNK-kinase inhibitor. It potently inhibits the in vitro kinase activity of all four WNK family members (WNK1, WNK2, WNK3, and WNK4) with IC50 of 5nM, 1nM, 6nM, and 9nM. Selective WNK1, IC50: 5nM; WNK2, IC50: 1nM; WNK3, IC50: 6nM; WNK4, IC50: 9nM
S0015 WNK-IN-11 WNK-IN-11 is a potent, selective, and orally acitve allosteric inhibitor of With-No-Lysine (WNK) kinase with IC50 of 4 nM for WNK1 enzyme. Selective WNK1, IC50: 4 nM