Home Autophagy ULK ULK2 Inhibitors

ULK2 Inhibitors

  • ULK1
  • ULK2
Catalog No. Product Name Information Selective / Pan IC50 / Ki
S7949 MRT68921 HCl MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively. Pan ULK2, IC50: 1.1 nM
S8793 ULK-101 ULK-101 is a potent and selective ULK1 inhibitor with IC50 values of 8.3 nM and 30 nM for ULK1 and ULK2, respectively. Pan ULK2, IC50: 30 nM
S3393 SBP-7455 SBP-7455 is a dual-Specific ULK1/2 autophagy inhibitor with IC50s of 13 nM and 476 nM for ULK1 and ULK2 in ADP-Glo assay, respectively. Pan ULK2, IC50: 476 nM
S7885 SBI-0206965 SBI-0206965 is a highly selective autophagy kinase ULK1 inhibitor with IC50 of 108 nM, about 7-fold selectivity over ULK2. SBI-0206965 inhibits autophagy and enhances apoptosis in human glioblastoma and lung cancer cells. Pan ULK2, IC50: 711 nM