Home Metabolism -Microbiology Thioredoxin Reductase TrxR Selective Inhibitors

TrxR Selective Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S4307 Auranofin Auranofin is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H. pylori TrxR in cell-free assay. Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1.2 μM. Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis. Selective TrxR, IC50: 88 nM