Home Metabolism Phospholipase (e.g. PLA) Smase Selective Inhibitors

Smase Selective Inhibitors

  • PLA2
  • PLC
  • PLD
  • LYPLA1
  • Smase
Catalog No. Product Name Information Selective / Pan IC50 / Ki
S7609 GW4869 GW4869 (GW69A, GW554869A) is a neutral, noncompetitive inhibitor of sphingomyelinase (SMase) with an IC50 of 1 μM. It is selective for N-SMase, and does not inhibit acid SMase at up to at least 150 μM, also is a commonly used exosome inhibitor. Selective SMase, IC50: 1 μM
S5913 Cambinol Cambinol is a novel uncompetitive nSMase2 inhibitor with a K i value of 7 μM (IC50 = 5 ± 1 μM). Selective nSMase2, Ki: 7 μM