• SIRT1
  • SIRT2
  • SIRT3
  • SIRT6
  • SIRT5

SIRT3 Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S8628 3-TYP 3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor which is selective for Sirt3 over Sirt1 and Sirt2. The IC50 values for SITR1, SIRT2, SIRT3 are 88 nM, 92 nM, 16 nM respectively. Pan SIRT3, IC50: 16 nM
S4900 Tenovin-6 Tenovin-6 is a small molecule activator of p53 transcriptional activity and inhibits dihydroorotate dehydrogenase (DHODH). Tenovin-6 is also an inhibitor of SirT1 and SirT2. Pan SIRT3, IC50: 67 μM