S1PR5 Agonists

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S7179 BAF312 (Siponimod)

BAF312 (Siponimod) is a next-generation S1P receptor modulator, selective for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, exhibits >1000-fold selectivity over S1P2, S1P3 and S1P4 receptors. Phase 3.

Pan S1P5 receptor, EC50: 0.98 nM