Home Apoptosis -Proteases Caspase Caspase-5 Inhibitors

Caspase-5 Inhibitors

  • Caspase-1
  • Caspase-3
  • Caspase-8
  • Caspase-9
  • Caspase-4
  • Capase-7
  • Caspase-2
  • Caspase-5
  • Caspase-6
  • Caspase-10
  • Caspase-7
Catalog No. Product Name Information Selective / Pan IC50 / Ki
S7901 Ac-DEVD-CHO Ac-DEVD-CHO (Caspase-3 Inhibitor I, N-Ac-Asp-Glu-Val-Asp-CHO) is a potent aldehyde inhibitor of Group II caspases with Ki values of 0.2 nM and 0.3 nM for for caspase-3 and caspase-7, respectively. Weak inhibition for caspase-2. Pan caspase-5, Ki: 205 nM
S9817 Ac-FLTD-CMK Ac-FLTD-CMK is a specific inhibitor for inflammatory caspases. Ac-FLTD-CMK inhibits gasdermin D (GSDMD) cleavage by caspases-1, -4, -5, and -11 in vitro. Ac-FLTD-CMK is effective against caspases-1, caspases-4 and caspases-5 with IC50 of 46.7 nM, 1.49 μM and 329 nM, respectively. Pan caspases-5, IC50: 329 nM