2D Structure
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2D chemical structural formula diagram.
3D Structure
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This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
Ziftomenib (KO-539)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 4-methyl-5-[[4-[[2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-1-[(2S)-2-(4-methylsulfonylpiperazin-1-yl)propyl]indole-2-carbonitrile | |
|---|---|---|
| CAS Number | 2134675-36-6 | |
| Molecular Formula |
C33H42F3N9O2S2 |
|
| Molecular Weight (MW) | 717.87 | |
| InChIKey | BGGALFIXXQOTPY-NRFANRHFSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(139.3 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(139.3 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 33 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(139.3 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 50 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(139.3 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 50 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(139.3 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 3 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Ziftomenib (KO-539) Mechanism of Action: Menin Inhibition in Leukemic Blasts Research
- Ziftomenib (KO-539) Clinical Trials
- Ziftomenib (KO-539) Solubility in DMSO
- Ziftomenib (KO-539) Stock Solution
- Ziftomenib (KO-539) Storage
- Ziftomenib (KO-539) Stability
- Ziftomenib (KO-539) Molecular Weight
- Ziftomenib (KO-539) CAS Number
- Ziftomenib (KO-539) MedChemExpress (HY-132001)? Try a better option.
- Ziftomenib (KO-539) Sigma (TA9H98DCB3CD)? Try a better option.
- Ziftomenib (KO-539) Cayman (45139)? Try a better option.
- Ziftomenib (KO-539) Abmole (M13430)? Try a better option.
- Ziftomenib (KO-539) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.