Clinical Trials

Numerous clinical trials have evaluated zidovudine across all development stages, from Early Phase 1 to Phase 4. These studies primarily address human immunodeficiency virus (HIV) infections, mother-to-child transmission, and HIV-2, while also investigating secondary conditions such as AIDS dementia complex, lipodystrophy, hepatitis B, and adult T-cell leukemia-lymphoma. Spanning completed, recruiting, active, and terminated protocols, these trials are supported by diverse sponsors, including government institutes, public health organizations, and pharmaceutical companies.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01419561 RECRUITING
KSHV Inflammatory Cytokine Syndrome (KICS); KSHV; HHV-8
National Cancer Institute (NCI)
2011-09-08 PHASE2
NCT00092222 ACTIVE_NOT_RECRUITING
Lymphoproliferative Disorder; HHV-8; Malignancy; HIV
National Cancer Institute (NCI)
2004-10-28 PHASE2
NCT02737046 COMPLETED
Adult T-cell Leukemia-Lymphoma; ATLL
University of Miami
2016-12-12 PHASE2
NCT04731103 COMPLETED
Aicardi-Goutières Syndrome
University of Edinburgh
2022-08-24 PHASE2
NCT00799864 COMPLETED
HIV-1
Janssen Sciences Ireland UC
2011-01 PHASE2
NCT03088410 COMPLETED
HIV; Insulin Sensitivity; Diabetes Mellitus
Ann & Robert H Lurie Children's Hospital of Chicago
2016-08-22 PHASE4
NCT02712801 COMPLETED
HIV/AIDS and Infections
National Center for Women and Children's Health, China CDC
2016-04 PHASE4
NCT02369406 ACTIVE_NOT_RECRUITING
HIV; Pediatric AIDS
Harvard School of Public Health (HSPH)
2015-05-04 PHASE2; PHASE3
NCT03988452 UNKNOWN
Human Immunodeficiency Virus
Makerere University
2019-07-30 PHASE3
NCT03394196 TERMINATED
HIV-2 Infection
University of Washington
2018-07-04
NCT02431975 COMPLETED
HIV
Columbia University
2015-08 PHASE4
NCT03991013 Completed
HIV Infections
University of Cape Town|Wellcome Trust|Médecins Sans Frontières Belgium
2019-08-08 Phase 2
NCT02150993 COMPLETED
HIV-2 Infection
ANRS, Emerging Infectious Diseases
2016-01-26 PHASE2; PHASE3
NCT00872872 COMPLETED
NVP Plasma Level; NVP Related Mutation; 3TC Related Mutation
Thai Red Cross AIDS Research Centre
2008-05
NCT02655471 COMPLETED
HTLV-I Infections; Tropical Spastic Paraparesis
Universidad Peruana Cayetano Heredia
2017-07-01 EARLY_PHASE1
NCT01618305 COMPLETED
HIV Infections
Westat
2013-09-05 PHASE4
NCT01964755 TERMINATED
Epstein Barr Virus Associated Non Hodgkin's Lymphoma; Epstein Barr Virus Associated Hodgkin's Lymphoma; Post-Transplant Lymphoproliferative Disease
University of Miami
2009-04-21 PHASE2
NCT01441063 COMPLETED
Castleman Disease; Multicentric Castleman Disease; Giant Lymph Node Hyperplasia
National Cancer Institute (NCI)
2011-09-13 PHASE2
NCT01125696 COMPLETED
HIV; Hepatitis B
Centers for Disease Control and Prevention
2012-05 PHASE2
NCT02832778 UNKNOWN
HIV
St Stephens Aids Trust
2016-11-21 PHASE1
NCT02363452 COMPLETED
Aicardi-Goutières Syndrome (AGS)
Assistance Publique - Hôpitaux de Paris
2015-09-10 PHASE2
NCT02499874 COMPLETED
HIV
St Stephens Aids Trust
2015-08 PHASE1
NCT01818258 COMPLETED
HIV Positive; Malnourished
International Maternal Pediatric Adolescent AIDS Clinical Trials Group
2015-10-26 PHASE4
NCT03642704 Completed
Mother to Child HIV Transmission
ANRS Emerging Infectious Diseases
2017-02-22 Phase 4
NCT03178084 COMPLETED
HIV/AIDS
Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
2014-10-15 PHASE3
NCT01061151 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2011-03-01 PHASE3
NCT01511237 COMPLETED
HIV Infections
Institut de Recherche pour le Developpement
2011-12 PHASE3
NCT00074581 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2005-02 PHASE3
NCT01352715 COMPLETED
HIV-1 Infection
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
2012-03-13 PHASE3
NCT01694017 COMPLETED
HIV
Tufts University
2012-11 PHASE4
NCT01738555 WITHDRAWN
Human Immunodeficiency Virus Infection
RFS Pharma, LLC
2013-04 PHASE2
NCT01340950 COMPLETED
HIV Infections; Central Nervous System Diseases; Dementia
University of California, San Diego
2010-07 PHASE4
NCT01714414 COMPLETED
HIV-1 Infection
Michael Hoelscher
2012-12 PHASE2
NCT01516970 COMPLETED
Human Immunodeficiency Virus (HIV)
Janssen-Cilag G.m.b.H
2011-11-25 PHASE3
NCT01565889 COMPLETED
Hepatitis C; HIV
Gilead Sciences
2012-03 PHASE1; PHASE2
NCT00719602 COMPLETED
HIV Infections; Malaria
International Maternal Pediatric Adolescent AIDS Clinical Trials Group
2009-08 EARLY_PHASE1
NCT00993031 COMPLETED
Malaria; HIV Infections
University of California, San Francisco
2009-12-15 PHASE3
NCT01583439 TERMINATED
HIV Infections
Harvard School of Public Health (HSPH)
2012-09
NCT01737359 TERMINATED
Human Immunodeficiency Virus Infection
RFS Pharma, LLC
2012-12 PHASE2
NCT00936195 WITHDRAWN
HIV Infection; Pregnancy; Breastfeeding; HIV Infections
French National Agency for Research on AIDS and Viral Hepatitis
2010-01 PHASE3
NCT01540240 UNKNOWN
HIV; Zidovudine Adverse Reaction
University Hospital, Geneva
2011-08 PHASE2; PHASE3
NCT01275625 COMPLETED
HIV
ViiV Healthcare
2011-06 PHASE4
NCT00102960 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2005-07 PHASE3
NCT00608569 COMPLETED
HIV Infections
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
2009-03
NCT01469520 UNKNOWN
HIV; AIDS
Elim Pediatric Pharmaceuticals Inc.
2010-10 PHASE1
NCT01088516 COMPLETED
HIV
University of Zambia
2008-12 PHASE4
NCT01772940 COMPLETED
HIV-1 Infection
Centre Hospitalier Universitaire Saint Pierre
2008-12 PHASE4
NCT00234091 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2006-04 PHASE3
NCT00424814 COMPLETED
HIV Infections
ANRS, Emerging Infectious Diseases
2007-03 PHASE2; PHASE3
NCT00573001 COMPLETED
HIV Infections
French National Agency for Research on AIDS and Viral Hepatitis
2008-07 PHASE3
NCT00854581 TERMINATED
Lymphoma; Precancerous/Nonmalignant Condition
University of Miami
2007-11 PHASE4
NCT00335322 COMPLETED
Human Immunodeficiency Virus (HIV)
Kirby Institute
2007-02 PHASE4
NCT00099359 COMPLETED
Disease Transmission, Vertical; Vertical Human Immunodeficiency Virus Transmission; HIV Infections
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
2004-02 PHASE3
NCT00307151 COMPLETED
HIV Infections
International Maternal Pediatric Adolescent AIDS Clinical Trials Group
2005-12 PHASE2
NCT00409591 TERMINATED
HIV Infections; Pregnancy
Institut de Recherche pour le Developpement
2008-07 PHASE3
NCT00346567 COMPLETED
HIV Infections
Rigshospitalet, Denmark
2006-06
NCT00915655 COMPLETED
HIV-1 Infection
Tibotec Pharmaceuticals, Ireland
2009-07 PHASE2
NCT00084136 COMPLETED
HIV Infections
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
2005-05 PHASE4
NCT00099632 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2006-03 PHASE2
NCT00001644 COMPLETED
HIV Infection
National Institute of Allergy and Infectious Diseases (NIAID)
1997-03-03 PHASE1
NCT00672412 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2008-10 PHASE1; PHASE2
NCT00164736 COMPLETED
HIV Infections
Centers for Disease Control and Prevention
2004-03 PHASE3
NCT00470041 COMPLETED
Healthy
University Ghent
2007-06 PHASE1
NCT00120510 COMPLETED
HIV Infections; Tuberculosis
National Institute of Allergy and Infectious Diseases (NIAID)
2007-07
NCT00405925 COMPLETED
HIV Infections
Rijnstate Hospital
2003-03 PHASE3
NCT00834457 COMPLETED
AIDS-related Kaposi's Sarcoma
Parirenyatwa Hospital
2007-06 PHASE2; PHASE3
NCT00100568 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2006-07
NCT00427297 TERMINATED
HIV Infections
University of Washington
2007-09 PHASE3
NCT00528957 COMPLETED
HIV Infections
Gilead Sciences
2006-12-28 PHASE3
NCT00270296 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2006-06 PHASE2
NCT00146380 COMPLETED
HIV Infections
Centers for Disease Control and Prevention
2003-07 PHASE2
NCT00966160 COMPLETED
Acquired Immunodeficiency Syndrome; HIV Infections
University of Cologne
1999-01 PHASE3
NCT00006441 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2003-02
NCT00109590 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2006-06 PHASE2
NCT01386970 COMPLETED
HIV
University of Colorado, Denver
2005-05 PHASE4
NCT00342355 COMPLETED
HIV
National Institutes of Health Clinical Center (CC)
2004-01 PHASE4
NCT00324649 COMPLETED
HIV-1
Gilead Sciences
2006-05 PHASE4
NCT00143689 COMPLETED
HIV; Mitochondrial Toxicity
University of British Columbia
2002-04 PHASE4
NCT00084149 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2004-02 PHASE2
NCT00851630 COMPLETED
HIV; Tuberculosis
Duke University
2004-06 PHASE4
NCT02229760 TERMINATED
HIV Infections
Boehringer Ingelheim
2006-08 PHASE1; PHASE2
NCT00323544 COMPLETED
HIV Infections
Gilead Sciences
2004-10 PHASE3
NCT00006617 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00100594 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2005-05
NCT00204308 COMPLETED
HIV; Pregnancy
University of North Carolina, Chapel Hill
2005-03 PHASE2
NCT00098293 COMPLETED
HIV-1
ViiV Healthcare
2004-11 PHASE3
NCT00234923 COMPLETED
HIV Infection
Abbott
2003-08 PHASE3
NCT00192595 COMPLETED
HIV Infection; Hepatitis B Coinfection
Kirby Institute
2004-01 PHASE4
NCT00144183 COMPLETED
Acquired Immunodeficiency Syndrome
Boehringer Ingelheim
2003-01 PHASE3
NCT00192621 COMPLETED
HIV Infections; Dyslipidemias; Glucose Metabolism Disorders; Metabolic Diseases; Lipodystrophy; Cardiovascular Disease
Kirby Institute
2004-11 PHASE4
NCT00141284 COMPLETED
HIV Infection; Hepatitis C
Pfizer
2005-10 PHASE4
NCT00041327 COMPLETED
Lymphoma
AIDS Malignancy Consortium
2002-10 PHASE2
NCT00192660 COMPLETED
HIV-Associated Lipodystrophy Syndrome; Cardiovascular Disease
Kirby Institute
2003-02 PHASE4
NCT00618176 COMPLETED
HIV Infections
Peking Union Medical College
2005-01 PHASE4
NCT00144157 COMPLETED
Acquired Immunodeficiency Syndrome
Boehringer Ingelheim
2003-06 PHASE4
NCT00142337 COMPLETED
HIV Infections
Institut de Recherche pour le Developpement
2004-12 PHASE2
NCT00082394 COMPLETED
Infection, Human Immunodeficiency Virus I; HIV Infection
GlaxoSmithKline
2004-04-26 PHASE4
NCT00104429 TERMINATED
Infection, Human Immunodeficiency Virus I; HIV Infection
ViiV Healthcare
2005-01 PHASE2
NCT00002524 COMPLETED
Lymphoma
M.D. Anderson Cancer Center
1993-06 PHASE2
NCT00000897 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00059358 COMPLETED
HIV Infections; Hepatitis C
National Institute of Allergy and Infectious Diseases (NIAID)
2001-09 PHASE1; PHASE2
NCT00167674 COMPLETED
HIV Infections
University of Washington
2003-11-03 PHASE2
NCT00779376 COMPLETED
Healthy
Ranbaxy Laboratories Limited
2005-02
NCT00112047 COMPLETED
HIV Infections
Gilead Sciences
2003-07 PHASE3
NCT00000993 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00000587 COMPLETED
Acquired Immunodeficiency Syndrome; Anemia; Hematologic Diseases; HIV Infections; Blood Disease
Thomas Jefferson University
1988-09 PHASE2
NCT00014937 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00273975 COMPLETED
HIV Infections
Boehringer Ingelheim
2002-01 PHASE2
NCT00647946 COMPLETED
Lipodystrophy
Gilead Sciences
2003-02 PHASE2
NCT00779233 COMPLETED
Healthy
Ranbaxy Laboratories Limited
2004-09
NCT00038506 COMPLETED
HIV Infection
ViiV Healthcare
2002-03 PHASE4
NCT00028327 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00001119 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
1999-10
NCT00002571 COMPLETED
Lymphoma
SWOG Cancer Research Network
1994-06 PHASE2
NCT00650637 TERMINATED
Diarrhea
Pfizer
2003-01 PHASE3
NCT00601562 COMPLETED
HIV Infections
Roxane Laboratories
2003-06
NCT00602550 COMPLETED
HIV Infections
Roxane Laboratories
2003-06
NCT00043888 COMPLETED
HIV Infections
GlaxoSmithKline
2002-01 PHASE3
NCT00000875 TERMINATED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00013897 COMPLETED
HIV Infections
Bristol-Myers Squibb
2001-02 PHASE3
NCT00006264 COMPLETED
Lymphoma
AIDS Malignancy Consortium
2000-07 PHASE2
NCT00272480 COMPLETED
HTLV-I-associated Myelopathy
Imperial College London
1999-11-08 PHASE2; PHASE3
NCT02249416 COMPLETED
Healthy
Boehringer Ingelheim
2001-11 PHASE1
NCT00021463 COMPLETED
HIV Infections; Lipodystrophy
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00002429 COMPLETED
HIV Infections
Bristol-Myers Squibb
1999-07 PHASE3
NCT00001066 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT02181933 COMPLETED
HIV Infections
Boehringer Ingelheim
1999-04 PHASE3
NCT02249130 COMPLETED
HIV Infections
Boehringer Ingelheim
1999-03 PHASE2
NCT00002411 COMPLETED
HIV Infections
Bristol-Myers Squibb
1998-03
NCT00000882 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00002371 COMPLETED
HIV Infections
Bristol-Myers Squibb
1996-06 PHASE3
NCT00000982 COMPLETED
Encephalopathies; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00001111 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00001040 COMPLETED
HIV Infections
Hoffmann-La Roche
PHASE2
NCT00000679 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000965 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00000662 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00000672 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000979 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000678 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000671 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000961 TERMINATED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00001008 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00000716 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000659 TERMINATED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00002020 COMPLETED
HIV Infections
Glaxo Wellcome
NCT00002324 COMPLETED
HIV Infections
Boehringer Ingelheim
PHASE2
NCT00000971 COMPLETED
Mycobacterium Avium-intracellulare Infection; HIV Infections
Abbott
PHASE1
NCT00002386 COMPLETED
HIV Infections; Hemophilia A
Merck Sharp & Dohme LLC
PHASE4
NCT00002274 COMPLETED
HIV Infections; Leukoencephalopathy, Progressive Multifocal
Bristol-Myers Squibb
NCT00000841 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00000878 COMPLETED
HIV Infections; Pregnancy
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000765 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00000918 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00002401 COMPLETED
HIV Infections
Pharmacia and Upjohn
NCT00000719 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00001045 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00122226 UNKNOWN
HIV Infections; HIV-Associated Lipodystrophy Syndrome
Amsterdam UMC, location VUmc
2003-01 PHASE4
NCT00080522 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2005-02
NCT00004998 SUSPENDED
HIV Infections
Agouron Pharmaceuticals
1999-11 PHASE2
NCT00000687 COMPLETED
Sarcoma, Kaposi; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00002190 COMPLETED
HIV Infections
Hoffmann-La Roche
PHASE2
NCT00001075 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00002236 COMPLETED
HIV Infections
Pharmacia and Upjohn
NCT00002369 COMPLETED
HIV Infections
Bristol-Myers Squibb
NCT00000791 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00002255 COMPLETED
HIV Infections
Amgen
PHASE1
NCT00002110 COMPLETED
HIV Infections
Mylan Laboratories
PHASE2
NCT00002217 COMPLETED
HIV Infections
Glaxo Wellcome
NCT00002269 COMPLETED
HIV Infections
HEM Research
NCT00002290 COMPLETED
HIV Infections
Glaxo Wellcome
NCT00004736 COMPLETED
HIV Infections; Tuberculosis
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000651 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00000664 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000834 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002109 COMPLETED
HIV Infections
Immunobiology Research Institute
PHASE3
NCT00002034 COMPLETED
Cytomegalovirus Retinitis; HIV Infections
Hoffmann-La Roche
NCT00001067 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00006396 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00000851 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00217503 COMPLETED
Lymphoma
National Cancer Institute (NCI)
2005-07 PHASE2
NCT00158405 COMPLETED
HIV Infections
French National Agency for Research on AIDS and Viral Hepatitis
2002-12 PHASE3
NCT00000864 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002400 COMPLETED
HIV Infections
Pharmacia and Upjohn
NCT00000862 COMPLETED
HIV Infections; Pregnancy
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000823 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000738 COMPLETED
AIDS Dementia Complex; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000754 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00398684 COMPLETED
HIV Infections; Pregnancy
Institut de Recherche pour le Developpement
2001-01 PHASE3
NCT00001035 COMPLETED
HIV Infections; Hepatitis C
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00001113 COMPLETED
Sarcoma, Kaposi; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002285 COMPLETED
HIV Infections
Glaxo Wellcome
NCT00000896 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00002279 COMPLETED
HIV Infections
Hoffmann-La Roche
NCT00000770 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000923 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00000727 COMPLETED
Pneumonia, Pneumocystis Carinii; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00001095 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00086359 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2004-07 PHASE3
NCT00000656 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000888 COMPLETED
HIV Infections; Pregnancy
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000649 COMPLETED
HIV Infections
Boehringer Ingelheim
PHASE1
NCT00078247 COMPLETED
HIV Infections; Tuberculosis
National Institute of Allergy and Infectious Diseases (NIAID)
2004-10 PHASE3
NCT00000838 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00002435 COMPLETED
HIV Infections
Pharmacia
PHASE2
NCT00002035 COMPLETED
HIV Infections
Bristol-Myers Squibb
NCT00002288 COMPLETED
HIV Infections
Glaxo Wellcome
NCT00000718 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00004585 COMPLETED
HIV Infections
Glaxo Wellcome
1999-10 PHASE4
NCT00000700 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00000990 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00002334 COMPLETED
HIV Infections
Hoffmann-La Roche
PHASE3
NCT00005002 UNKNOWN
HIV Infections
Agouron Pharmaceuticals
PHASE3
NCT00001084 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00386230 COMPLETED
HIV Infections; Pregnancy
Institut de Recherche pour le Developpement
1997-06 PHASE3
NCT00000711 COMPLETED
HIV Infections; Cytopenias
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000661 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00001997 COMPLETED
HIV Infections
Chiron Corporation
NCT00000902 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002168 COMPLETED
HIV Infections
Bristol-Myers Squibb
NCT00002280 COMPLETED
HIV Infections
Bristol-Myers Squibb
NCT00002013 COMPLETED
HIV Infections
Wyeth is now a wholly owned subsidiary of Pfizer
NCT00000978 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000709 COMPLETED
AIDS Dementia Complex; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00002391 COMPLETED
HIV Infections
Glaxo Wellcome
PHASE3
NCT00002323 COMPLETED
HIV Infections
Boehringer Ingelheim
NCT00002276 COMPLETED
HIV Infections; Hemophilia A
University of Pittsburgh
NCT00050895 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00001354 COMPLETED
Acquired Immunodeficiency Syndrome; HIV Infection
National Institute of Allergy and Infectious Diseases (NIAID)
1993-03 PHASE2
NCT00000960 COMPLETED
HIV Infections; Pregnancy
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00000916 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000810 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002199 COMPLETED
HIV Infections
Glaxo Wellcome
PHASE3
NCT00001011 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00002263 COMPLETED
HIV Infections; Cytopenias
Sandoz
NCT00000647 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00389194 COMPLETED
HIV Infections
International Antiviral Therapy Evaluation Center
2006-04 PHASE4
NCT00002322 COMPLETED
HIV Infections
Pharmacia and Upjohn
PHASE2
NCT00001112 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00139178 COMPLETED
HIV Associated Lipodystrophy Syndrome.; HIV; Hypercholesterolemia; Lipoatrophy
Danish HIV Research Group
2004-03 PHASE4
NCT00000919 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00004852 COMPLETED
HIV Infections
Glaxo Wellcome
1999-09 PHASE2
NCT00000652 COMPLETED
HIV Infections
National Cancer Institute (NCI)
PHASE1
NCT00001063 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000693 COMPLETED
Cytomegalovirus Retinitis; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00002216 COMPLETED
HIV Infections
Glaxo Wellcome
NCT00000781 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00002047 COMPLETED
HIV Infections; Kidney Failure, Chronic
Glaxo Wellcome
NCT00002044 COMPLETED
AIDS Dementia Complex; Neuromuscular Diseases; HIV Infections
Glaxo Wellcome
NCT00001993 COMPLETED
HIV Infections
G D Searle
PHASE2
NCT00000728 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00001002 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000751 COMPLETED
HIV Infections; Pregnancy
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
PHASE3
NCT00087945 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
2004-07
NCT00000732 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00000681 COMPLETED
Sarcoma, Kaposi; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002347 COMPLETED
HIV Infections
Parexel
PHASE2
NCT00002443 COMPLETED
HIV Infections
Merck Sharp & Dohme LLC
NCT00002312 COMPLETED
HIV Infections
Pharmacia and Upjohn
NCT00004981 UNKNOWN
HIV Infections
Glaxo Wellcome
PHASE3
NCT00000865 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000742 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002270 COMPLETED
HIV Infections; Leukoencephalopathy, Progressive Multifocal
University of Miami
NCT00002033 COMPLETED
HIV Infections
Wyeth is now a wholly owned subsidiary of Pfizer
NCT00000994 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00001010 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002286 COMPLETED
HIV Infections; Psoriasis
Glaxo Wellcome
NCT00002117 COMPLETED
HIV Infections
Hoffmann-La Roche
PHASE3
NCT00000973 COMPLETED
Toxoplasmosis, Cerebral; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000695 COMPLETED
Sarcoma, Kaposi; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00005106 COMPLETED
HIV Infections
Glaxo Wellcome
1999-09 PHASE4
NCT00002409 COMPLETED
HIV Infections
Glaxo Wellcome
PHASE3
NCT00002124 COMPLETED
HIV Infections
Pharmacia and Upjohn
PHASE3
NCT00017719 COMPLETED
HIV Infections; Pregnancy
National Institute of Allergy and Infectious Diseases (NIAID)
2002-05 PHASE3
NCT00000999 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002410 COMPLETED
HIV Infections
Dupont Merck
PHASE3
NCT00000685 WITHDRAWN
HIV Infections; Kidney Disease
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000800 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002006 COMPLETED
HIV Infections; Cytopenias
Sandoz
PHASE1
NCT00001087 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00004999 SUSPENDED
HIV Infections
Agouron Pharmaceuticals
1999-08 PHASE2
NCT00002284 COMPLETED
Lymphoma, Non-Hodgkin; HIV Infections
Glaxo Wellcome
NCT00000723 TERMINATED
Lymphoma, Non-Hodgkin; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00002046 COMPLETED
HIV Infections
Glaxo Wellcome
NCT00000995 COMPLETED
Cytomegalovirus Infections; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00002256 COMPLETED
HIV Infections
Hoffmann-La Roche
NCT00001057 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00002063 COMPLETED
HIV Infections
Glaxo Wellcome
NCT00256828 COMPLETED
HIV Infections
Clinical Trial Agency of HIV Study Group
2004-06 PHASE4
NCT00001049 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002023 COMPLETED
HIV Infections
Glaxo Wellcome
NCT00002333 COMPLETED
HIV Infections
Hoffmann-La Roche
PHASE2
NCT00000887 COMPLETED
HIV Infections; Pregnancy
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002108 COMPLETED
HIV Infections
Glaxo Wellcome
NCT00002155 COMPLETED
HIV Infections
Merck Sharp & Dohme LLC
NCT00162643 UNKNOWN
Acquired Immunodeficiency Syndrome
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
2004-12 PHASE4
NCT00002079 COMPLETED
HIV Infections
G D Searle
PHASE2
NCT00003261 UNKNOWN
Lymphoma
Centro di Riferimento Oncologico - Aviano
1997-05 PHASE2
NCT00002183 COMPLETED
HIV Infections
Glaxo Wellcome
PHASE1
NCT00000986 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00011895 UNKNOWN
HIV Infections
GlaxoSmithKline
2001-02 PHASE4
NCT00000831 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00001001 COMPLETED
HIV Infections; Liver Diseases
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00013520 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00199979 UNKNOWN
Hiv Infection With Antiretroviral Therapy Indication; CD4 Below 350/µL or Below 15%
MEDEX
2005-04 PHASE3
NCT00002203 COMPLETED
HIV Infections
Glaxo Wellcome
NCT00270556 COMPLETED
HIV
Gilead Sciences
2003-01 PHASE2
NCT00002379 COMPLETED
HIV Infections
Gilead Sciences
PHASE2
NCT00001282 COMPLETED
HIV Infection
National Institute of Allergy and Infectious Diseases (NIAID)
1991-07 PHASE2
NCT00001048 COMPLETED
HIV Infections; Leukoencephalopathy, Progressive Multifocal
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00002378 COMPLETED
HIV Infections
Hoffmann-La Roche
PHASE3
NCT00000885 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00102206 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00001036 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002281 COMPLETED
HIV Infections; Cytopenias
Amgen
NCT00002436 COMPLETED
HIV Infections
Glaxo Wellcome
PHASE3
NCT00000637 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00000734 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00002001 COMPLETED
HIV Infections
Glaxo Wellcome
NCT00000983 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00002326 COMPLETED
HIV Infections
Gilead Sciences
PHASE1
NCT00002048 COMPLETED
Lymphatic Disease; HIV Infections
Glaxo Wellcome
NCT00000818 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000725 COMPLETED
Sarcoma, Kaposi; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000789 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00002238 COMPLETED
HIV Infections
Bayer
PHASE3
NCT00000991 COMPLETED
Pneumonia, Pneumocystis Carinii; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00002357 COMPLETED
HIV Infections
Hoechst Marion Roussel
PHASE2
NCT00000736 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00000976 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000696 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00001032 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00001267 COMPLETED
AIDS-Related Complex; Acquired Immunodeficiency Syndrome
National Cancer Institute (NCI)
1990-10 PHASE3
NCT00000706 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00000944 COMPLETED
HIV Infections; Pregnancy
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000987 COMPLETED
Sarcoma, Kaposi; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000743 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00001104 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00002096 COMPLETED
Cytomegalovirus Infections; HIV Infections
Hoffmann-La Roche
PHASE1
NCT00002045 COMPLETED
HIV Infections
Glaxo Wellcome
NCT00034086 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00005000 UNKNOWN
HIV Infections
Agouron Pharmaceuticals
1999-12 PHASE4
NCT00127959 COMPLETED
HIV Infections; Hepatitis B
International Antiviral Therapy Evaluation Center
2004-03 PHASE4
NCT00000680 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002007 COMPLETED
HIV Infections; Cytopenias
Sandoz
NCT00001022 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00001007 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00014014 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000712 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00001005 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002307 COMPLETED
HIV Infections
Bristol-Myers Squibb
NCT00000657 COMPLETED
AIDS Dementia Complex; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000629 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000701 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00001094 WITHDRAWN
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00043953 COMPLETED
HIV Infections
Abbott
2002-08 PHASE2
NCT00002905 UNKNOWN
Lymphoma
Centro di Riferimento Oncologico - Aviano
1995-06 PHASE2
NCT00001106 COMPLETED
HIV Infections; Pregnancy
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000702 COMPLETED
AIDS Dementia Complex; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00002265 COMPLETED
HIV Infections
Hoffmann-La Roche
PHASE2
NCT00002081 COMPLETED
HIV Infections
Hoffmann-La Roche
NCT00000628 COMPLETED
HIV Infections
Merck Sharp & Dohme LLC
PHASE1
NCT00002287 COMPLETED
HIV Infections
Glaxo Wellcome
NCT00000855 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00000952 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002184 COMPLETED
HIV Infections
Gilead Sciences
PHASE2
NCT00002028 COMPLETED
HIV Infections
Bristol-Myers Squibb
NCT00005764 COMPLETED
HIV Infections; Lipodystrophy
Glaxo Wellcome
2000-05 PHASE4
NCT00000703 COMPLETED
Lymphoma, Non-Hodgkin; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00002162 COMPLETED
HIV Infections
Hoffmann-La Roche
PHASE2
NCT00000670 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00000753 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000967 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002389 COMPLETED
HIV Infections
Glaxo Wellcome
PHASE3
NCT00000760 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00001989 COMPLETED
HIV Infections
Genelabs Technologies
PHASE2
NCT00002320 COMPLETED
HIV Infections
Glaxo Wellcome
PHASE3
NCT00000705 COMPLETED
HIV Infections; Hemophilia A
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00002376 COMPLETED
HIV Infections
Merck Sharp & Dohme LLC
PHASE4
NCT00002416 COMPLETED
HIV Infections
Triangle Pharmaceuticals
PHASE3
NCT00432016 COMPLETED
HIV Infections
RFS Pharma, LLC
2007-02 PHASE1; PHASE2
NCT00002367 COMPLETED
HIV Infections
Hoffmann-La Roche
PHASE3
NCT00000625 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000682 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00001085 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000989 COMPLETED
Cytomegalovirus Retinitis; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00197613 COMPLETED
AIDS; HIV Infection
Harvard School of Public Health (HSPH)
2002-12 PHASE3
NCT00000750 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00001025 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000891 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00199121 UNKNOWN
HIV
Johann Wolfgang Goethe University Hospital
PHASE4
NCT00000920 COMPLETED
HIV Infections; Pregnancy
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000755 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00000731 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00000963 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000969 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00000872 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000870 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000803 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00001003 COMPLETED
Pneumonia, Pneumocystis Carinii; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00002208 COMPLETED
HIV Infections
Merck Sharp & Dohme LLC
PHASE3
NCT00000720 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00001029 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00002086 COMPLETED
HIV Infections
Glaxo Wellcome
PHASE2
NCT00075231 COMPLETED
HIV Infections
Abbott
2003-12 PHASE2
NCT00001083 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000903 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE3
NCT00002195 COMPLETED
HIV Infections
Glaxo Wellcome
PHASE3
NCT00031070 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE2
NCT00000814 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1
NCT00001024 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00002014 COMPLETED
HIV Infections
Glaxo Wellcome
PHASE1
NCT00002179 COMPLETED
HIV Infections
Merck Sharp & Dohme LLC
PHASE4
NCT00000694 COMPLETED
Sarcoma, Kaposi; HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
PHASE1

(data from https://clinicaltrials.gov, updated on 2026-08-25)

Check the Zidovudine product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Zidovudine is a nucleoside analog reverse transcriptase inhibitor that, upon intracellular conversion to its active triphosphate state, competes with natural thymidine to selectively inhibit HIV reverse transcriptase and terminate viral DNA strand elongation. By halting the synthesis and integration of viral double-stranded DNA into host genetic material, zidovudine suppresses viral replication to manage HIV infections and prevent mother-to-child viral transmission.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

Note: Technical data last updated: Sep 1, 2026.