For research use only. Not for use in humans.

Zalifrelimab (Anti-CTLA-4 / CD152)

Synonyms: AGEN1884 Cat.No.A2860 Purity:99%

Zalifrelimab (Anti-CTLA-4 / CD152) is a recombinant human monoclonal antibody directed against the human T-cell receptor cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4), with immune checkpoint inhibitory and antineoplastic activities. MW: 144.48 KD.

Quality Control

Batch: A286001 Purity: 99% Protein concentration: 5.533mg/ml Endotoxin Level: ＜1EU/mg

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COA
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Datasheet

Specificity

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Zalifrelimab (Anti-CTLA-4 / CD152) is a recombinant human monoclonal antibody directed against the human T-cell receptor cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4), with immune checkpoint inhibitory and antineoplastic activities. MW: 144.48 KD.
References	[1] https://pubmed.ncbi.nlm.nih.gov/34932394/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	2148321-69-9
Molecular Weight	144.48
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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