Cell-free Assays (IC50/Ki) for VVD-214 (VVD-133214, RO7589831)
| Key Target | IC50 (Cell-free) | Description | Reference |
|---|---|---|---|
| hWRN⁵¹⁹⁻¹²²⁷ | 0.13 μM | helicase assay; endpoint measurement of fluorescence (ex./em. 535/585 nm) | PM40964743 |
Cell-based Assay (IC50) for VVD-214 (VVD-133214, RO7589831)
| Cell Type | IC50 (Cell-based) | Description | Reference |
|---|---|---|---|
| HCT116 | 0.043 μM | CTG2.0 reagent; luminescence read on a CLARIOstar plate reader | PM40964743 |
| SW480 | >20 μM | CTG2.0 reagent; luminescence read on a CLARIOstar plate reader | PM40964743 |
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VVD-214 (VVD-133214, RO7589831)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
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- VVD-214 (VVD-133214, RO7589831) Mechanism of Action: WRN Helicase Inhibition in MSI-H Cancer Cell Research
- VVD-214 (VVD-133214, RO7589831) Working Concentration | Cell Culture | Treatment
- VVD-214 (VVD-133214, RO7589831) Solubility in DMSO
- VVD-214 (VVD-133214, RO7589831) Stock Solution
- VVD-214 (VVD-133214, RO7589831) Storage
- VVD-214 (VVD-133214, RO7589831) Stability
- VVD-214 (VVD-133214, RO7589831) Molecular Weight
- VVD-214 (VVD-133214, RO7589831) CAS Number
- VVD-214 (VVD-133214, RO7589831) Chemical Structure (2D and 3D)
- VVD-214 (VVD-133214, RO7589831) Sigma (BL3H9A8E1F70)? Try a better option.
- VVD-214 (VVD-133214, RO7589831) MedChemExpress (HY-158116)? Try a better option.
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- VVD-214 (VVD-133214, RO7589831) SDS｜MSDS