Vorinostat is a potent, reversible pan-HDAC inhibitor. It affects Akt/mTOR signaling by chelating zinc, promoting apoptosis.
Vorinostat (SAHA) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Vorinostat (SAHA) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.