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Verteporfin SDS | MSDS

1.PRODUCT AND COMPANY IDENTIFICATION

Product identifier

  • Product Name: Verteporfin
  • Catalog Number: S1786
  • CAS Number: 129497-78-5
  • IUPAC Name: (4R,4aS)-rel-18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoic acid monomethyl ester

Relevant identified uses and uses advised against

  • Identified uses: For research and development use only; laboratory chemicals; manufacture of substances.
  • Uses advised against: Not for pharmaceutical, household, or other unapproved uses.

Details of the supplier

  • Company : Selleck Chemicals
  • TollFree : +1 877 796-6397
  • Tel : +1 832 582-8158
  • Fax : +1 832 582-8590

Emergency telephone number

  • Emergency phone #: +1 832 582-8158

2. HAZARDS IDENTIFICATION

GHS Classification:
In accordance with the OSHA Hazard Communication Standard (29 CFR 1910.1200), the product as supplied is not classified as a hazardous substance or mixture.

Other Hazards:
None known.

GHS Label Elements:
No hazard pictograms, signal words, hazard statements, or precautionary statements are required for this product.

3. COMPOSITION/INFORMATION ON INGREDIENTS

Substance/Mixture: Substance
Chemical Name: (4R,4aS)-rel-18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoic acid monomethyl ester
CAS-No.: 129497-78-5
Components: No hazardous ingredients are present in this substance.

4. FIRST AID MEASURES

If Inhaled: Move the person to fresh air.
In Case of Skin Contact: Immediately remove all contaminated clothing. Rinse the skin with water or shower.
In Case of Eye Contact: Rinse eyes thoroughly with plenty of water. Remove contact lenses if present.
If Swallowed: Provide the victim with water to drink (maximum of two glasses). Consult a physician if the individual feels unwell.
Most Important Symptoms and Effects: The most important known symptoms and effects are described in the labeling (see Section 2) and/or in Section 11.
Protection of First-Aiders: Refer to Section 8 for personal protective equipment.
Notes to Physician: N/A.

5. FIREFIGHTING MEASURES

Suitable Extinguishing Media: Water, Foam, Carbon dioxide (CO2), Dry powder.
Unsuitable Extinguishing Media: No limitations of extinguishing agents are specified for this substance.
Specific Hazards: The material is combustible. Hazardous combustion gases or vapors (Carbon oxides, Nitrogen oxides) may be generated in the event of a fire.
Specific Extinguishing Methods: N/A.
Further Information: Use water spray to suppress gases, vapors, or mists. Prevent firefighting water from entering surface water or groundwater systems.
Special Protective Equipment: Wear self-contained breathing apparatus for firefighting if necessary.

6. ACCIDENTAL RELEASE MEASURES

Personal Precautions and Emergency Procedures:

  • For non-emergency personnel: Avoid inhalation of dusts. Evacuate the danger area, observe emergency procedures, and consult an expert.
  • For emergency responders: Refer to Section 8 for personal protection.

Environmental Precautions: Do not allow the product to enter drains.
Methods and Materials for Containment and Cleaning Up: Cover drains. Collect, bind, and pump off spills. Observe material restrictions (see Sections 7 and 10). Take up the material dry and dispose of it properly. Clean the affected area and avoid the generation of dusts.

7. HANDLING AND STORAGE

Precautions for Safe Handling: Refer to Section 2.2 for precautions.
Conditions for Safe Storage: Keep the container tightly closed and in a dry place.
Storage Class: 11, Combustible powder.
Recommended Storage Temperature: -4 °F / -20 °C.
Further Information on Storage Stability: The material is light-sensitive. Store with a desiccant.

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Workplace Control Parameters: Contains no substances with occupational exposure limit values.
Engineering Measures: N/A.
Personal Protective Equipment:

  • Respiratory Protection: Required when dusts are generated. Recommended filter type: P1 (based on DIN EN 143, DIN 14387).
  • Hand Protection: Handle with impervious nitrile rubber gloves.
    • Full contact: 0.11 mm thickness, >480 min breakthrough time (KCL 741 Dermatril L).
    • Splash contact: 0.11 mm thickness, >480 min breakthrough time (KCL 741 Dermatril L).
  • Eye Protection: Use safety glasses tested and approved under standards such as NIOSH (US) or EN 166 (EU).
  • Hygiene Measures: Change contaminated clothing and wash hands after working with the substance.

9. PHYSICAL AND CHEMICAL PROPERTIES

Appearance: powder
Color: black
Odor: N/A
Odor Threshold: N/A
pH: N/A
Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Evaporation Rate: N/A
Flammability (solid, gas): N/A
Upper/Lower Flammability Limits: N/A
Vapor Pressure: N/A
Relative Vapor Density: N/A
Relative Density: N/A
Density: N/A
Water Solubility: Slightly soluble (68 °F / 20 °C)
Solubility in Other Solvents: Soluble in dimethyl sulfoxide (68 °F / 20 °C)
Partition Coefficient (n-octanol/water): N/A
Autoignition Temperature: N/A
Decomposition Temperature: N/A
Viscosity: N/A
Explosive Properties: N/A
Oxidizing Properties: None
Molecular Weight: 718.79 g/mol

10. STABILITY AND REACTIVITY

Reactivity: Flammable organic substances in fine distribution may generally pose a dust explosion potential when whirled up.
Chemical Stability: The product is chemically stable under standard ambient conditions (room temperature).
Possibility of Hazardous Reactions: N/A.
Conditions to Avoid: No information available.
Incompatible Materials: N/A.
Hazardous Decomposition Products: In the event of fire, see Section 5.

11. TOXICOLOGICAL INFORMATION

Acute Toxicity: N/A for oral, inhalation, or dermal routes.
Skin Corrosion/Irritation: N/A.
Serious Eye Damage/Irritation: N/A.
Respiratory or Skin Sensitization: N/A.
Germ Cell Mutagenicity: N/A.
Carcinogenicity:

  • IARC: No component present at levels >= 0.1% is identified as a probable, possible, or confirmed human carcinogen.
  • NTP: No component present at levels >= 0.1% is identified as a known or anticipated carcinogen.
  • OSHA: No component present at levels >= 0.1% is on OSHA's list of regulated carcinogens.
    Reproductive Toxicity: N/A.
    STOT - Single Exposure: N/A.
    STOT - Repeated Exposure: N/A.
    Aspiration Hazard: N/A.
    Additional Information: To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.

12. ECOLOGICAL INFORMATION

Ecotoxicity: N/A.
Persistence and Degradability: N/A.
Bioaccumulative Potential: N/A.
Mobility in Soil: N/A.
Other Adverse Effects: N/A.

13. DISPOSAL CONSIDERATIONS

Waste Treatment Methods: Waste material must be disposed of in accordance with national and local regulations. Leave chemicals in their original containers. Do not mix with other waste. Handle uncleaned containers in the same manner as the product itself.

14. TRANSPORT INFORMATION

IATA-DGR: Not regulated as a dangerous good.
IMDG-Code: Not regulated as a dangerous good.
Transport in Bulk: Not applicable for the product as supplied.
49 CFR Road: Not regulated as a dangerous good.
Poison Inhalation Hazard: No.
Special Precautions for User: Not classified as dangerous in the meaning of transport regulations.

15. REGULATORY INFORMATION

CERCLA Reportable Quantity
This material does not contain any components with a CERCLA RQ.

SARA 304 Extremely Hazardous Substances Reportable Quantity
This material does not contain any components with a section 304 EHS RQ.

SARA 302 Extremely Hazardous Substances Threshold Planning Quantity
This material does not contain any components with a section 302 EHS TPQ.

SARA 311/312 : No SARA Hazards
Hazards

SARA 313 : This material does not contain any chemical
components with known CAS numbers that exceed the
threshold (De Minimis) reporting levels established by
SARA Title III, Section 313.

US State Regulations
Massachusetts Right To Know
No components are subject to the Massachusetts Right to Know Act.

Maine Chemicals of High Concern
Product does not contain any listed chemicals

Vermont Chemicals of High Concern
Product does not contain any listed chemicals

Washington Chemicals of High Concern
Product does not contain any listed chemicals

The components of this product are reported in the following inventories:
TSCA : Product contains substance(s) not listed on TSCA
inventory.

TSCA list
No substances are subject to a Significant New Use Rule.
No substances are subject to TSCA 12(b) export notification requirements.

16. OTHER INFORMATION

Revision Date: 2026/07/07
Further Information: The information provided is believed to be correct but is not exhaustive and should be used only as a guideline based on current knowledge. It does not represent a guarantee of the properties of the product. Selleck Chemicals Corporation and its Affiliates shall not be held liable for any damage resulting from handling or contact with the product.

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