CAS No. 6893-02-3
| IUPAC Name | (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid | |
|---|---|---|
| CAS Number | 6893-02-3 | |
| Molecular Formula |
C15H12I3NO4 |
|
| Molecular Weight (MW) | 650.97 | |
| SMILES | C1=CC(=C(C=C1OC2=C(C=C(C=C2I)CC(C(=O)O)N)I)I)O | |
| InChIKey | AUYYCJSJGJYCDS-LBPRGKRZSA-N |
Liothyronine (Triiodothyronine, T3) is an active thyroid hormone that functions as an agonist of nuclear thyroid hormone receptors. Upon binding to its receptors, it modulates gene transcription to regulate critical metabolic pathways, mitochondrial respiration, and cellular oxygen consumption. These nuclear actions drive key physiological processes, including body temperature regulation, tissue growth and differentiation, metabolic homeostasis, and cardiovascular function. [1][2]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(153.61 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| 0.1M NAOH | 1.56 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(153.61 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(153.61 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| 0.1M NAOH | 13 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(153.61 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| 0.1M NAOH | 10 mg/mL |
| Water | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
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- Liothyronine (Triiodothyronine, T3) Clinical Trials
- Liothyronine (Triiodothyronine, T3) Solubility in DMSO
- Liothyronine (Triiodothyronine, T3) Stock Solution
- Liothyronine (Triiodothyronine, T3) Storage
- Liothyronine (Triiodothyronine, T3) Stability
- Liothyronine (Triiodothyronine, T3) Molecular Weight
- Liothyronine (Triiodothyronine, T3) SMILES
- Liothyronine (Triiodothyronine, T3) Chemical Structure (2D and 3D)
- Liothyronine (Triiodothyronine, T3) SDS｜MSDS