Synonyms: IL-33,DVS27
Tozorakimab (Anti-IL-33) is a human immunoglobulin G1 monoclonal antibody targeting interleukin-33. It can be used to research chronic obstructive pulmonary disease. MW :144.54 KD.
| Featured Inhibitors | Y-27632 Dihydrochloride SB431542 CHIR-99021 (Laduviglusib) RMC-7977 RMC-6236 (Daraxonrasib) MRTX1133 MG132 Z-VAD-FMK VT3989 IAG933 |
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| Description |
Tozorakimab (Anti-IL-33) is a human immunoglobulin G1 monoclonal antibody targeting interleukin-33. It can be used to research chronic obstructive pulmonary disease. MW :144.54 KD.
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References |
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| CAS No. | 2376858-66-9 |
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| Isotype | Human IgG1 |
| Source | CHO |
| Formulation | 100 mM Pro-Ac, 20mM Arg, pH5.0 |
| Storage (From the date of receipt) |
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)
| NCT Number | Recruitment | interventions | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|---|
| NCT07566195 | RECRUITING | Drug: Tozorakimab Dose Regimen 1|Drug: Tozorakimab Dose Regi | Chronic Obstructive Pulmonary Disease; COPD | AstraZeneca | 2026-05-05 | PHASE3 |
| NCT05624450 | RECRUITING | Drug: Tozorakimab|Drug: Placebo | Viral Lung Infection and Acute Respiratory Failure | AstraZeneca | 2022-12-13 | PHASE3 |
| NCT06932263 | RECRUITING | Drug: Tozorakimab|Drug: Placebo | Asthma | AstraZeneca | 2025-03-26 | PHASE2 |
| NCT06897748 | COMPLETED | Drug: Placebo|Drug: Tozorakimab | Chronic Obstructive Pulmonary Disease (COPD) | AstraZeneca | 2025-04-12 | PHASE2 |
| NCT06040086 | COMPLETED | Drug: Placebo|Drug: Tozorakimab | Chronic Obstructive Pulmonary Disease (COPD) | AstraZeneca | 2023-09-22 | PHASE3 |
| NCT05742802 | COMPLETED | Chronic Obstructive Pulmonary Disease (COPD) | AstraZeneca | 2023-03-06 | PHASE3 |
(data from https://clinicaltrials.gov, updated on 2026-08-27)
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