Tomaralimab (Anti-TLR2 / CD282)

Synonyms: OPN-305

For research use only. Not for use in humans.

Tomaralimab (Anti-TLR2 / CD282) is a humanized immunoglobulin (Ig) G4 monoclonal antibody directed against toll-like receptor type 2 (TLR2) with potential anti-inflammatory and antineoplastic activities. It has the potential for research on Myelodysplastic Syndromes (MDS). MW : 145.5 KD.

Tomaralimab (Anti-TLR2 / CD282)

Purity & Quality Control

Batch: A233301 Purity: 99% Protein concentration: 4.731mg/ml Endotoxin Level: <1EU/mg
99

Choose Selective TLR Inhibitors

Name Citation TLR7 TLR8 TLR9 TLR4 TLR2 TLR3 TLR1 Others
Enpatoran Hydrochloride 0
CU-CPT-8m 1
CU-CPT9a 2
MD2-IN-1 3
Cu-CPT22 8
Okanin 0 NF-κB
AMG-9810 0 hTRPV1,rTRPV1
TLR4-IN-C34 6
E6446 4 DNA-TLR9
TLR2-IN-C29 18
MD2-TLR4-IN-1 0 IL-6,TNF-α
IAXO-102 0 NF-κB,MAPK
E6446 dihydrochloride 3
Resatorvid (TAK-242) 61 IL-6,NO,TNF-α
Ginsenoside Rb1 4 IFN-β,TNF-α,NF-κB
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Tomaralimab (Anti-TLR2 / CD282) is a humanized immunoglobulin (Ig) G4 monoclonal antibody directed against toll-like receptor type 2 (TLR2) with potential anti-inflammatory and antineoplastic activities. It has the potential for research on Myelodysplastic Syndromes (MDS). MW : 145.5 KD.

Product Details

CAS No. 1449294-76-1
Molecular Weight 145.5 kDa
Isotype Human IgG4SP
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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