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For research use only. Not for use in humans.
Tilvestamab (Anti-AXL / UFO)
Synonyms: BGB149
Tilvestamab (Anti-AXL / UFO) is a humanized antibody targeting AXL.Tilvestamab can be used in cancer research, particularly in AXL overexpressing renal cell carcinomas. MW :146.16 KD.
Quality Control
Specificity
| Name | Citation | Axl | Others |
|---|---|---|---|
| BMS-777607 | 63 | RON,Met,Tyro3 | |
| Bemcentinib (R428) | 131 | ||
| XL092 | 0 | VEGFR2,MER,MET | |
| UNC2025 | 7 | FLT3,Mer,TrkA | |
| Ningetinib | 0 | VEGFR2,c-Met | |
| Tamnorzatinib (ONO-7475) | 4 | Mer,FLT3 | |
| RU-301 | 0 | ||
| Sitravatinib (MGCD516) | 7 | DDR2,EPHA3,Mer | |
| CEP-40783 (RXDX-106) | 7 | c-Met,Tyro3,MER | |
| S49076 | 1 | Met,Mer,FGFR3 | |
| Merestinib (LY2801653) | 11 | DDR1,Met,DDR2 | |
| SGI-7079 | 4 | YES,Mer,Met | |
| UNC2025 HCl | 9 | Mer,FLT3,Tyro3 | |
| Dubermatinib(TP-0903) | 19 | ||
| NPS-1034 | 3 | Met | |
| LDC1267 | 9 | Mer,Tyro3 | |
| PF-07265807 | 0 | Mer |
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.
Mechanism of Action
| Description |
Tilvestamab (Anti-AXL / UFO) is a humanized antibody targeting AXL.Tilvestamab can be used in cancer research, particularly in AXL overexpressing renal cell carcinomas. MW :146.16 KD.
|
References |
|---|
Product Details
| CAS No. | 2226775-26-2 |
|---|---|
| Molecular Weight | 146.16 |
| Isotype | Human IgG1 |
| Source | CHO |
| Purification | AKTA |
| Sterility | 0.2 μM filtered |
| Formulation | 100 mM Pro-Ac, 20mM Arg, pH5.0 |
| Storage (From the date of receipt) |
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
Comparison of Clones for
*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)
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