SMILES:
C1CN1P(=S)(N2CC2)N3CC3
Chemical Structure
Check the
Thiotepa
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | tris(aziridin-1-yl)-sulfanylidene-λ5-phosphane | |
|---|---|---|
| CAS Number | 52-24-4 | |
| Molecular Formula |
C6H12N3PS |
|
| Molecular Weight (MW) | 189.22 | |
| SMILES | C1CN1P(=S)(N2CC2)N3CC3 | |
| InChIKey | FOCVUCIESVLUNU-UHFFFAOYSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
38 mg/mL
(200.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 13 mg/mL |
| Water | 3 mg/mL |
| DMSO |
100 mg/mL
(528.48 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 100 mg/mL |
| DMSO |
100 mg/mL
(528.48 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | 100 mg/mL |
| DMSO |
38 mg/mL
(200.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 38 mg/mL |
| Ethanol | 38 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.