Molecular Weight: 194.15 g/mol

TMZ(Temozolomide) Chemical Structure
Chemical Structure
Check the TMZ(Temozolomide) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 39 mg/mL (200.87 mM) ; Warmed with 60°C water bath ; Ultrasonicated
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 10 mg/mL (超声加热五分钟)
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Aliquotting Service

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Chemical Information

IUPAC Name 3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
CAS Number 85622-93-1
Molecular Formula

C6H6N6O2

Molecular Weight (MW) 194.15
SMILES CN1C(=O)N2C=NC(=C2N=N1)C(=O)N
InChIKey BPEGJWRSRHCHSN-UHFFFAOYSA-N
Note: Technical data last updated: Sep 1, 2026.