Temozolomide has been evaluated in numerous clinical trials spanning Early Phase I through Phase IV to assess its efficacy across malignancies including glioblastoma multiforme, high-grade gliomas, diffuse intrinsic pontine glioma, and triple-negative breast cancer. Sponsored by academic medical centers, pediatric hospitals, biopharmaceutical companies, and national cancer institutes, these studies encompass recruiting, active not recruiting, completed, and terminated statuses. Additionally, several Phase I and Phase II clinical trials explore temozolomide monotherapy or combination regimens for newly diagnosed and recurrent brain tumors.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT07591493 | NOT_YET_RECRUITING | Pancreatic Neuroendocrine Tumors (pNET); Pancreatic Neuroendocrine Tumors |
Gustave Roussy, Cancer Campus, Grand Paris |
2026-09 | PHASE3 |
| NCT06477939 | NOT_YET_RECRUITING | Glioblastoma |
Institut de cancérologie Strasbourg Europe |
2025-01-01 | PHASE3 |
| NCT07389278 | NOT_YET_RECRUITING | Glioblastoma; High-Grade Glioma (WHO III-IV); High-grade Glioma; Diffuse Midline Glioma, H3 K27M-Mutant; Diffuse Hemispheric Glioma, H3G34 Mutant |
Sabine Mueller, MD, PhD |
2026-03-09 | PHASE1; PHASE2 |
| NCT06419946 | RECRUITING | Glioblastoma, IDH-wildtype; MGMT-Methylated Glioblastoma |
Vastra Gotaland Region |
2025-02-01 | PHASE3 |
| NCT07195591 | RECRUITING | Glioblastoma |
GT Medical Technologies, Inc. |
2025-12-10 | PHASE3 |
| NCT07346157 | RECRUITING | Medulloblastoma; Medulloblastoma, Childhood; Medulloblastoma Recurrent |
Sabine Mueller, MD, PhD |
2026-08-21 | PHASE1; PHASE2 |
| NCT07549321 | RECRUITING | High-Risk Neuroblastoma |
Renaissance Pharma Ltd. |
2026-03-30 | PHASE2; PHASE3 |
| NCT03935685 | ACTIVE_NOT_RECRUITING | Glioma of Brain |
University of California, Irvine |
2019-02-26 | PHASE2 |
| NCT07334301 | RECRUITING | Relapsed Neuroblastoma |
University of Birmingham |
2024-11-11 | PHASE1; PHASE2 |
| NCT06448286 | NOT_YET_RECRUITING | Glioblastoma |
Jonsson Comprehensive Cancer Center |
2026-12-01 | PHASE3 |
| NCT06208657 | RECRUITING | Childhood Cancer; Childhood Solid Tumor; Childhood Brain Tumor; Recurrent Cancer; Refractory Cancer |
Australian & New Zealand Children's Haematology/Oncology Group |
2024-07-10 | PHASE1; PHASE2 |
| NCT07562971 | NOT_YET_RECRUITING | Diffuse Midline Glioma, H3 K27-Altered |
UMC Utrecht |
2026-05 | PHASE1; PHASE2 |
| NCT06861244 | RECRUITING | Embryonal Tumor With Multilayered Rosettes; Embryonal Tumor With Multilayered Rosettes, Nos |
University of California, San Francisco |
2025-03-06 | PHASE2 |
| NCT07762716 | NOT_YET_RECRUITING | Glioblastoma (GBM) |
BreakBio Corp |
2026-09 | PHASE1; PHASE2 |
| NCT07141771 | NOT_YET_RECRUITING | SCLC, Extensive Stage |
Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
2025-12-31 | PHASE1; PHASE2 |
| NCT01356290 | RECRUITING | Medulloblastoma Recurrent; Ependymoma Recurrent; ATRT Recurrent; Rare CNS Tumor Recurrent |
Medical University of Vienna |
2014-04 | PHASE2 |
| NCT06721689 | RECRUITING | Refractory Solid Tumors; Relapsed Solid Tumors; Relapsed Neuroblastoma; Refractory Neuroblastoma; Relapsed Rhabdomyosarcoma; Refractory Rhabdomyosarcoma |
Theodore Laetsch |
2025-03-23 | PHASE1; PHASE2 |
| NCT06805305 | RECRUITING | Glioblastoma (GBM) |
Diakonos Oncology Corporation |
2025-03-17 | PHASE2 |
| NCT06172296 | RECRUITING | Ganglioneuroblastoma, Nodular; Neuroblastoma |
National Cancer Institute (NCI) |
2024-04-19 | PHASE3 |
| NCT00887146 | ACTIVE_NOT_RECRUITING | Brain and Central Nervous System Tumors |
Alliance for Clinical Trials in Oncology |
2009-09 | PHASE3 |
| NCT07243470 | RECRUITING | Glioma; CNS Tumor, Adult; CNS Tumor, Childhood |
Centre Leon Berard |
2025-11-04 | PHASE1; PHASE2 |
| NCT07605364 | NOT_YET_RECRUITING | Advanced Glioblastoma |
Alliance for Clinical Trials in Oncology |
2026-06-10 | PHASE2; PHASE3 |
| NCT07569042 | RECRUITING | Malignant Neoplasm of Brain |
Novelwise Pharmaceutical Corporation |
2026-04-20 | PHASE1; PHASE2 |
| NCT07501104 | NOT_YET_RECRUITING | Melanoma (Skin Cancer) |
Shanghai Zhongshan Hospital |
2026-05-01 | PHASE2 |
| NCT05843253 | RECRUITING | High Grade Glioma; Diffuse Intrinsic Pontine Glioma; Anaplastic Astrocytoma; Glioblastoma; Glioblastoma Multiforme; Diffuse Midline Glioma, H3 K27M-Mutant; Metastatic Brain Tumor; WHO Grade III Glioma; WHO Grade IV Glioma; Diffuse Hemispheric Glioma, H3 G34-Mutant |
Nationwide Children's Hospital |
2024-08-22 | PHASE2 |
| NCT03899155 | RECRUITING | Cancer |
Bristol-Myers Squibb |
2019-08-09 | PHASE2 |
| NCT07758062 | NOT_YET_RECRUITING | Glioblastoma |
Tianjin Medical University General Hospital |
2026-09-01 | PHASE2 |
| NCT07754734 | NOT_YET_RECRUITING | Glioma; Glioblastoma (GBM); MGMT-Methylated Glioblastoma |
Dongguan People's Hospital |
2026-08-10 | PHASE2 |
| NCT06528496 | RECRUITING | High-risk Neuroblastoma; Neuroblastoma; Childhood Neuroblastoma |
Memorial Sloan Kettering Cancer Center |
2024-07-22 | PHASE2 |
| NCT06816927 | RECRUITING | Newly Diagnosed Glioblastoma |
Duke University |
2025-11-28 | PHASE2 |
| NCT06161974 | RECRUITING | High Grade Glioma; Astrocytoma; Astrocytoma, Grade III; Astrocytoma, Grade IV; Diffuse Intrinsic Pontine Glioma; WHO Grade III Glioma; WHO Grade IV Glioma; Metastatic Brain Tumor; Diffuse Midline Glioma, H3 K27M-Mutant; Thalamus Tumor; Spinal Tumor; IDH1 Mutation; IDH1 R132; IDH1 R132C; IDH1 R132H; IDH1 R132S; IDH1 R132G; IDH1 R132L; Oligodendroglioma |
Rigel Pharmaceuticals |
2025-02-01 | PHASE2 |
| NCT06410248 | RECRUITING | Recurrent Glioblastoma, IDH-Wildtype; Recurrent WHO Grade 2 Glioma; Recurrent WHO Grade 3 Glioma; Recurrent WHO Grade 4 Glioma |
Northwestern University |
2024-07-23 | PHASE1 |
| NCT06556563 | RECRUITING | Glioblastoma |
NovoCure GmbH |
2025-02-03 | PHASE3 |
| NCT07120984 | NOT_YET_RECRUITING | Glioma |
Philogen S.p.A. |
2026-01-30 | PHASE2 |
| NCT05236036 | ACTIVE_NOT_RECRUITING | Astrocytoma; Glioblastoma; Glioblastoma, IDH-Wildtype; MGMT-Unmethylated Glioblastoma; Recurrent Glioblastoma |
Northwestern University |
2022-08-08 | PHASE1 |
| NCT01777919 | NOT_YET_RECRUITING | Glioblastoma Multiforme |
Olympion Medical Center |
2027-01 | PHASE2 |
| NCT04199026 | RECRUITING | Metastatic Sarcoma; Recurrent Sarcoma; Resectable Sarcoma |
M.D. Anderson Cancer Center |
2025-02-25 | |
| NCT07365280 | NOT_YET_RECRUITING | Glioblastoma |
ZSky Biotech Inc |
2026-01-09 | PHASE2 |
| NCT06450041 | RECRUITING | Neuroblastoma |
New Approaches to Neuroblastoma Therapy Consortium |
2024-12-16 | PHASE2 |
| NCT04121455 | ACTIVE_NOT_RECRUITING | Glioblastoma |
TME Pharma AG |
2019-09-12 | PHASE1; PHASE2 |
| NCT06709495 | RECRUITING | Sarcoma; Sarcoma, Ewing; Desmoplastic Small Round Cell Tumor; Refractory Sarcoma; Osteosarcoma; Rhabdomyosarcoma |
David S Shulman, MD |
2025-01-27 | PHASE1; PHASE2 |
| NCT07326566 | RECRUITING | Glioblastoma (GBM); Newly Diagnosed Glioblastoma; GBM; Glioblastoma Multiforme (GBM); Glioma; Central Nervous System Diseases; Brain Cancer |
Black Diamond Therapeutics, Inc. |
2026-05-05 | PHASE2 |
| NCT05004116 | RECRUITING | Advanced Cancer; Metastatic Solid Tumor |
Memorial Sloan Kettering Cancer Center |
2021-08-09 | PHASE1; PHASE2 |
| NCT04339036 | RECRUITING | Neuroendocrine Tumor Grade 2; Neuroendocrine Tumors |
Abramson Cancer Center at Penn Medicine |
2021-10-07 | PHASE2 |
| NCT06995872 | RECRUITING | Neuroblastoma |
National Cancer Institute (NCI) |
2025-10-21 | PHASE1 |
| NCT03213002 | RECRUITING | Glioblastoma Multiforme (GBM); Glioblastoma; Glioma of Brain; Glioblastoma, Adult; Brain Tumor; Brain Tumor, Primary; Brain Tumor Adult; Cancer; Brain Cancer |
Northwell Health |
2017-06-13 | PHASE1; PHASE2 |
| NCT07457307 | NOT_YET_RECRUITING | High-grade Glioma |
NYU Langone Health |
2026-06 | PHASE1 |
| NCT06012695 | RECRUITING | Malignant Neoplasm; Malignant Neoplasm of Brain |
Novelwise Pharmaceutical Corporation |
2023-08-11 | PHASE1; PHASE2 |
| NCT05128734 | NOT_YET_RECRUITING | Breast Cancer Triple Negative |
AHS Cancer Control Alberta |
2026-04-01 | PHASE2 |
| NCT05106296 | RECRUITING | Ependymoma; Medulloblastoma; Glioblastoma; Primary Brain Tumor |
Theodore S. Johnson |
2022-02-08 | PHASE1 |
| NCT04394858 | ACTIVE_NOT_RECRUITING | Advanced Adrenal Gland Pheochromocytoma; Advanced Paraganglioma; Metastatic Adrenal Gland Pheochromocytoma; Metastatic Paraganglioma; Stage III Adrenal Gland Pheochromocytoma and Sympathetic Paraganglioma AJCC v8; Stage IV Adrenal Gland Pheochromocytoma and Sympathetic Paraganglioma AJCC v8; Unresectable Adrenal Gland Pheochromocytoma; Unresectable Paraganglioma |
National Cancer Institute (NCI) |
2021-03-17 | PHASE2 |
| NCT05100641 | NOT_YET_RECRUITING | Primary Glioblastoma |
Aivita Biomedical, Inc. |
2024-01 | PHASE3 |
| NCT05417594 | RECRUITING | Advanced Solid Malignancies |
AstraZeneca |
2022-06-24 | PHASE1; PHASE2 |
| NCT07085338 | RECRUITING | Neuroblastoma Recurrent |
St. Jude Children's Research Hospital |
2025-11-10 | PHASE2 |
| NCT02977780 | RECRUITING | Glioblastoma |
David Reardon, MD |
2017-02-09 | PHASE2 |
| NCT07457775 | NOT_YET_RECRUITING | Soft Tissue Sarcoma (Excluding GIST) |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2026-03-31 | PHASE2 |
| NCT06504381 | RECRUITING | High Grade Glioma; MGMT-Unmethylated Glioblastoma; MGMT-Methylated Glioblastoma |
University of California, San Francisco |
2025-01-08 | PHASE1; PHASE2 |
| NCT05902169 | RECRUITING | Glioblastoma; Recurrent Glioblastoma; GBM |
CarThera |
2024-01-29 | PHASE3 |
| NCT07015242 | RECRUITING | Lymphoma |
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company |
2025-11-06 | PHASE2 |
| NCT05083754 | RECRUITING | Glioblastoma Multiforme |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2022-08-31 | PHASE1 |
| NCT06218524 | NOT_YET_RECRUITING | Glioblastoma Multiforme |
Southern Medical University, China |
2024-12-01 | PHASE2 |
| NCT07310784 | RECRUITING | Advanced Melanoma |
Suzhou BlueHorse Therapeutics Co., Ltd. |
2025-12-16 | PHASE2 |
| NCT04919382 | RECRUITING | Extensive Stage Lung Small Cell Carcinoma; Metastatic Lung Small Cell Carcinoma; Recurrent Lung Small Cell Carcinoma; Stage IV Lung Cancer AJCC v8; Stage IVA Lung Cancer AJCC v8; Stage IVB Lung Cancer AJCC v8 |
Dwight Owen |
2022-01-26 | PHASE2 |
| NCT06220552 | RECRUITING | Recurrent Glioblastoma |
Fifth Affiliated Hospital, Sun Yat-Sen University |
2023-12-27 | PHASE2 |
| NCT07670026 | RECRUITING | Glioblastoma |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2025-12-01 | PHASE2 |
| NCT05342883 | ACTIVE_NOT_RECRUITING | Glioblastoma |
GT Medical Technologies, Inc. |
2022-08-17 | PHASE4 |
| NCT06297512 | RECRUITING | Glioblastoma |
Iacopo Sardi |
2022-12-09 | PHASE2 |
| NCT06478212 | ACTIVE_NOT_RECRUITING | IDH1-mutant Glioma; IDH2-mutant Glioma |
Institut de Recherches Internationales Servier |
2025-01-22 | PHASE1; PHASE2 |
| NCT06202066 | SUSPENDED | Digestive System Neuroendocrine Neoplasm; Lung Neuroendocrine Neoplasm; Malignant Solid Neoplasm; Pancreatic Neuroendocrine Neoplasm |
Roswell Park Cancer Institute |
2026-10-15 | PHASE2 |
| NCT07599371 | RECRUITING | Relapsed/Refractory Glioma |
The First Affiliated Hospital of Zhengzhou University |
2024-10-10 | PHASE1; PHASE2 |
| NCT07476794 | RECRUITING | Glioblastoma |
Sunnybrook Health Sciences Centre |
2025-11-01 | PHASE2 |
| NCT06008106 | RECRUITING | Melanoma |
Shanghai Kechow Pharma, Inc. |
2023-11-02 | PHASE3 |
| NCT04116411 | ACTIVE_NOT_RECRUITING | Glioblastoma Multiforme |
Cecilia Soderberg-Naucler |
2019-09-04 | PHASE2 |
| NCT05030298 | RECRUITING | Malignant Glioma |
Mayo Clinic |
2023-05-23 | PHASE1 |
| NCT07191431 | RECRUITING | Lymphoma Cns |
Ruijin Hospital |
2025-09-22 | |
| NCT07138001 | NOT_YET_RECRUITING | Recurrent Glioblastoma |
Sichuan Honghe Biotechnology Co., Ltd. |
2025-08 | PHASE2 |
| NCT07027748 | RECRUITING | Neuroblastoma; Neuroblastoma Recurrent; Relapsed Neuroblastoma; Refractory Neuroblastoma |
Steven DuBois, MD |
2025-06-27 | PHASE1 |
| NCT05432804 | RECRUITING | Recurrent Glioblastoma, IDH-Wildtype; Recurrent MGMT-Methylated Glioblastoma |
National Cancer Institute (NCI) |
2023-03-20 | PHASE1; PHASE2 |
| NCT04919226 | ACTIVE_NOT_RECRUITING | Neuroendocrine Tumors |
ITM Solucin GmbH |
2021-12-21 | PHASE3 |
| NCT07092306 | NOT_YET_RECRUITING | Ewing's Sarcoma |
Tang Xiaodong |
2025-08-10 | PHASE2 |
| NCT05999994 | RECRUITING | Neoplasms; Child; Adolescent |
Eli Lilly and Company |
2020-01-22 | PHASE2 |
| NCT06850766 | RECRUITING | IDH-Wildtype Glioblastoma; Glioblastoma (GBM) |
Ottawa Hospital Research Institute |
2025-05-08 | |
| NCT07193654 | RECRUITING | Glioblastoma (GBM) |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2025-04-01 | PHASE2 |
| NCT06827717 | RECRUITING | Ewing Sarcoma |
Sun Yat-sen University |
2025-04-15 | PHASE2 |
| NCT05691491 | RECRUITING | Advanced Malignant Solid Neoplasm; Advanced Microsatellite Stable Colorectal Carcinoma; Hematopoietic and Lymphatic System Neoplasm; Metastatic Malignant Solid Neoplasm; Metastatic Microsatellite Stable Colorectal Carcinoma; Stage III Colorectal Cancer AJCC v8; Stage IV Colorectal Cancer AJCC v8 |
National Cancer Institute (NCI) |
2023-09-28 | PHASE1; PHASE2 |
| NCT01837862 | ACTIVE_NOT_RECRUITING | Pilomyxoid Astrocytoma; Pilocytic Astrocytoma; Glioma, Astrocytic; Optic Nerve Glioma; Pleomorphic Xanthoastrocytoma; Glioblastoma Multiforme; Anaplastic Astrocytoma; Gliosarcoma; Diffuse Intrinsic Pontine Glioma; DIPG; Low-grade Glioma; Brainstem Glioma |
Julie Krystal |
2013-10-22 | PHASE1; PHASE2 |
| NCT04047706 | ACTIVE_NOT_RECRUITING | Glioblastoma |
Northwestern University |
2019-08-13 | PHASE1 |
| NCT02331498 | ACTIVE_NOT_RECRUITING | Glioblastoma Multiforme |
Centre Antoine Lacassagne |
2015-06 | PHASE1; PHASE2 |
| NCT06649851 | RECRUITING | MGMT-Methylated Glioblastoma; Glioblastoma (GBM); Newly Diagnosed Glioblastoma Multiforme |
Massachusetts General Hospital |
2025-04-02 | PHASE2 |
| NCT04485949 | ACTIVE_NOT_RECRUITING | Glioblastoma |
Imvax |
2023-03-20 | PHASE2 |
| NCT04165941 | ACTIVE_NOT_RECRUITING | Brain Tumor Adult |
University of Alabama at Birmingham |
2020-02-11 | PHASE1 |
| NCT04890093 | SUSPENDED | Sarcoma, Ewing; Rhabdomyosarcoma |
National Cancer Institute (NCI) |
2024-10-31 | PHASE1; PHASE2 |
| NCT06739395 | RECRUITING | Solid Tumor; Precision Medicine |
Tianjin Medical University Second Hospital |
2024-11-01 | PHASE2 |
| NCT03491683 | ACTIVE_NOT_RECRUITING | Glioblastoma |
Inovio Pharmaceuticals |
2018-05-31 | PHASE1; PHASE2 |
| NCT06006273 | RECRUITING | Refractory Solid Tumors |
M.D. Anderson Cancer Center |
2023-08-16 | PHASE1 |
| NCT06330337 | RECRUITING | Glioma |
The Third Affiliated hospital of Zhejiang Chinese Medical University |
2024-04-01 | PHASE3 |
| NCT04623931 | RECRUITING | Anaplastic Astrocytoma, IDH-Wildtype; Anaplastic Oligoastrocytoma; Anaplastic Oligodendroglioma; Diffuse Astrocytoma, IDH-Wildtype; Glioblastoma; Oligoastrocytoma; Oligodendroglioma; WHO Grade II Glioma; WHO Grade III Glioma |
M.D. Anderson Cancer Center |
2020-01-30 | PHASE2 |
| NCT06013618 | RECRUITING | Neuroblastoma |
Sun Yat-Sen University Cancer Center |
2023-06-19 | PHASE2 |
| NCT06475235 | RECRUITING | Lymphoma; Primary Central Nervous System Lymphoma |
Dana-Farber Cancer Institute |
2024-10-18 | PHASE1 |
| NCT05634707 | ACTIVE_NOT_RECRUITING | Primary Brain Tumor; Brain Tumor, Recurrent |
Duke University |
2023-08-05 | EARLY_PHASE1 |
| NCT05685004 | ACTIVE_NOT_RECRUITING | Glioblastoma Multiforme of Brain |
TVAX Biomedical |
2023-09-15 | PHASE2; PHASE3 |
| NCT04337177 | ACTIVE_NOT_RECRUITING | Solid Tumors; Neuroblastoma; Rhabdomyosarcoma; Ewing Sarcoma; Hepatoblastoma; Medulloblastoma |
Valent Technologies, LLC |
2021-10-25 | PHASE1 |
| NCT05400603 | RECRUITING | Neuroblastoma; Refractory Neuroblastoma; Relapsed Neuroblastoma; Relapsed Osteosarcoma; Refractory Osteosarcoma |
Emory University |
2023-11-06 | PHASE1 |
| NCT04922723 | ACTIVE_NOT_RECRUITING | Glioblastoma |
West Virginia University |
2022-10-03 | PHASE1; PHASE2 |
| NCT05769660 | RECRUITING | Glioblastoma Multiforme |
BeyondBio Inc. |
2022-11-29 | PHASE1 |
| NCT05781321 | ACTIVE_NOT_RECRUITING | Glioblastoma |
Mayo Clinic |
2023-03-23 | PHASE2 |
| NCT03212742 | ACTIVE_NOT_RECRUITING | Malignant Gliomas; Radiotherapy; PARP Inhibitor |
Centre Francois Baclesse |
2017-09-04 | PHASE1; PHASE2 |
| NCT03528642 | ACTIVE_NOT_RECRUITING | Astrocytoma, IDH-Mutant, Grade 2; Astrocytoma, IDH-Mutant, Grade 3 |
National Cancer Institute (NCI) |
2019-05-01 | PHASE1 |
| NCT02203526 | ACTIVE_NOT_RECRUITING | Primary Central Nervous System Lymphoma |
National Cancer Institute (NCI) |
2014-08-14 | PHASE1 |
| NCT04752813 | ACTIVE_NOT_RECRUITING | Glioblastoma; Glioblastoma Multiforme |
BPGbio |
2022-08-22 | PHASE2 |
| NCT06595186 | RECRUITING | Glioblastoma Multiforme (GBM) |
JenKem Technology Co., Ltd. |
2022-10-31 | PHASE2 |
| NCT05789043 | RECRUITING | Acral Melanoma |
Peking University Cancer Hospital & Institute |
2023-03-21 | PHASE3 |
| NCT06514313 | RECRUITING | Soft Tissue Sarcoma |
Yizhuo Zhang |
2024-07-03 | PHASE2 |
| NCT01189643 | ACTIVE_NOT_RECRUITING | Sarcoma; Desmoplastic Small Round Cell Tumor (DSRCT) |
Memorial Sloan Kettering Cancer Center |
2010-08 | EARLY_PHASE1 |
| NCT07047066 | NOT_YET_RECRUITING | Glioblastoma |
Tongji Hospital |
2025-07-10 | PHASE2 |
| NCT03180502 | ACTIVE_NOT_RECRUITING | Anaplastic Astrocytoma; Anaplastic Oligoastrocytoma; Anaplastic Oligodendroglioma; Diffuse Astrocytoma; Glioma; Oligoastrocytoma; Oligodendroglioma; WHO Grade 3 Glioma |
NRG Oncology |
2018-01-23 | PHASE2 |
| NCT04796454 | WITHDRAWN | Platinum-Sensitive Biliary Tract Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
2022-05 | PHASE2 |
| NCT05879367 | RECRUITING | Glioblastoma, IDH-wildtype; Glioblastoma; Glioblastoma Multiforme; Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype; GBM; Astrocytoma; Astrocytoma, IDH-Mutant |
Orbus Therapeutics, Inc. |
2023-07-24 | PHASE1 |
| NCT03749187 | ACTIVE_NOT_RECRUITING | Glioblastoma; IDH1 Gene Mutation; IDH2 Gene Mutation; Low Grade Glioma; Malignant Glioma; Recurrent Glioblastoma; Recurrent WHO Grade II Glioma; Recurrent WHO Grade III Glioma; WHO Grade II Glioma; WHO Grade III Glioma |
University of California, San Francisco |
2019-04-03 | PHASE1 |
| NCT05457829 | RECRUITING | Rhabdomyosarcoma, Child |
Sun Yat-sen University |
2023-12-30 | PHASE2 |
| NCT04457284 | COMPLETED | Colorectal Adenocarcinoma |
Memorial Sloan Kettering Cancer Center |
2020-11-18 | PHASE2 |
| NCT05052957 | RECRUITING | Glioblastoma Multiforme; Glioblastoma Multiforme, Adult; Supratentorial Glioblastoma; Supratentorial Gliosarcoma |
Leland Metheny |
2023-01-20 | PHASE2 |
| NCT04164199 | COMPLETED | Advanced Malignancies |
BeOne Medicines |
2019-12-19 | PHASE3 |
| NCT05463848 | ACTIVE_NOT_RECRUITING | Glioblastoma; Recurrent Glioblastoma |
L. Nicolas Gonzalez Castro, MD, PhD |
2022-10-21 | PHASE2 |
| NCT06703398 | RECRUITING | Melanoma |
Shanghai Juncell Therapeutics |
2024-12-20 | PHASE2 |
| NCT04689347 | RECRUITING | Metastatic Colorectal Cancer |
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
2021-01-01 | PHASE1; PHASE2 |
| NCT04743661 | ACTIVE_NOT_RECRUITING | Recurrent Medulloblastoma; Recurrent Ependymoma |
Pediatric Brain Tumor Consortium |
2022-04-04 | PHASE2 |
| NCT04817254 | COMPLETED | Glioblastoma; Gliosarcoma; Malignant Glioma |
National Cancer Institute (NCI) |
2021-12-08 | PHASE2 |
| NCT06490536 | RECRUITING | Colon Cancer Stage II; Colon Cancer Stage III |
IFOM ETS - The AIRC Institute of Molecular Oncology |
2024-10-22 | PHASE3 |
| NCT04250922 | ACTIVE_NOT_RECRUITING | Primary Glioblastoma; Glioblastoma Multiforme |
Laminar Pharmaceuticals |
2019-12-01 | PHASE2; PHASE3 |
| NCT06710821 | NOT_YET_RECRUITING | Solid Tumor Cancer |
Yizhuo Zhang |
2024-12-01 | PHASE1 |
| NCT04267978 | RECRUITING | Glioblastoma, Recurrent; Lower Grade Glioma, Recurrent |
Beijing Sanbo Brain Hospital |
2020-02-13 | PHASE2 |
| NCT04961515 | RECRUITING | Primary Central Nervous System Hodgkin Lymphoma |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2021-07-01 | PHASE2 |
| NCT05512481 | RECRUITING | Melanoma; Acral Melanoma; Temozolomide; Apatinib; Camrelizumab; Neoadjuvant; Pathological Response |
Peking University Cancer Hospital & Institute |
2022-09-13 | PHASE2 |
| NCT03728361 | COMPLETED | Grade I Neuroendocrine Carcinoma; Grade II Neuroendocrine Carcinoma; Grade III Neuroendocrine Carcinoma; Metastatic Neuroendocrine Carcinoma; Neuroendocrine Carcinoma; Recurrent Small Cell Lung Carcinoma; Refractory Small Cell Lung Carcinoma; Lung Cancer Stage IV; Large Cell Neuroendocrine Carcinoma; Neuroendocrine Tumors; Small Cell Lung Cancer Metastatic; Small-cell Lung Cancer |
Dwight Owen |
2018-12-31 | PHASE2 |
| NCT05664243 | ACTIVE_NOT_RECRUITING | Glioblastoma |
In8bio Inc. |
2023-09-08 | PHASE1; PHASE2 |
| NCT02546102 | SUSPENDED | Glioblastoma Multiforme |
Precision Life Sciences Group |
2024-12 | PHASE3 |
| NCT04105374 | WITHDRAWN | Anaplastic Astrocytoma; Glioblastoma; Oligodendroglioma; Supratentorial Glioblastoma |
NRG Oncology |
2020-01-31 | PHASE2; PHASE3 |
| NCT03529448 | COMPLETED | Glioblastoma |
Grupo Español de Investigación en Neurooncología |
2023-08-18 | PHASE1; PHASE2 |
| NCT06625047 | COMPLETED | Astrocytoma, IDH-Mutant; Glioblastoma; Glioma; Oligodendroglioma, IDH-Mutant and 1p/19q-Codeleted |
Mayo Clinic |
2024-10-07 | PHASE4 |
| NCT05142241 | ACTIVE_NOT_RECRUITING | Malignant Solid Neoplasm |
National Cancer Institute (NCI) |
2022-07-11 | PHASE2 |
| NCT06553781 | NOT_YET_RECRUITING | Malignant Melanoma |
Fudan University |
2024-09-01 | |
| NCT04881032 | ACTIVE_NOT_RECRUITING | Glioblastoma |
Centre Jean Perrin |
2022-03-07 | PHASE1; PHASE2 |
| NCT04911621 | COMPLETED | High Grade Glioma; Diffuse Intrinsic Pontine Glioma |
University Hospital, Antwerp |
2021-09-10 | PHASE1; PHASE2 |
| NCT04501718 | RECRUITING | Recurrent Medulloblastoma |
Beijing Sanbo Brain Hospital |
2020-10-28 | PHASE2 |
| NCT05366062 | UNKNOWN | Glioma, Malignant |
Epitopoietic Research Corporation |
2022-07-01 | PHASE2 |
| NCT06353360 | UNKNOWN | Glioblastoma Multiforme |
Jiangsu Healthy Life Innovation Medical Technology Co., Ltd |
2024-04-30 | PHASE2 |
| NCT02179086 | ACTIVE_NOT_RECRUITING | Glioblastoma |
NRG Oncology |
2014-12-04 | PHASE2 |
| NCT06279767 | UNKNOWN | Glioblastoma; Cancer; Temozolomide |
The First Affiliated Hospital with Nanjing Medical University |
2022-07-01 | PHASE1; PHASE2 |
| NCT04967690 | UNKNOWN | Newly Diagnosed Glioblastoma |
Double Bond Pharmaceutical AB |
2024-01 | PHASE1 |
| NCT04523688 | RECRUITING | Glioblastoma; Vaccination |
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS |
2021-03-25 | PHASE2 |
| NCT04737889 | RECRUITING | Primary Central Nervous System Lymphoma |
Henan Cancer Hospital |
2021-01-13 | PHASE2 |
| NCT04077866 | UNKNOWN | Recurrent Glioblastoma; Refractory Glioblastoma |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2023-06-01 | PHASE1; PHASE2 |
| NCT06760117 | RECRUITING | Pediatric Solid Tumor |
Sun Yat-sen University |
2022-01-01 | PHASE1 |
| NCT01985087 | ACTIVE_NOT_RECRUITING | Glioblastoma |
University of Louisville |
2014-09 | PHASE1; PHASE2 |
| NCT03794349 | ACTIVE_NOT_RECRUITING | High Risk Neuroblastoma; Recurrent Neuroblastoma; Refractory Neuroblastoma |
Children's Oncology Group |
2019-07-08 | PHASE2 |
| NCT03334305 | TERMINATED | Malignant Glioma; High Grade Glioma |
University of Florida |
2018-08-27 | PHASE1 |
| NCT03396575 | TERMINATED | Diffuse Intrinsic Pontine Glioma (DIPG); Brain Stem Glioma |
University of Florida |
2018-07-17 | PHASE1 |
| NCT04747145 | ACTIVE_NOT_RECRUITING | Glioblastoma |
Medical College of Wisconsin |
2021-06-03 | PHASE2 |
| NCT00102648 | ACTIVE_NOT_RECRUITING | Malignant Supratentorial Neoplasm; Recurrent Glioblastoma; Recurrent Gliosarcoma |
M.D. Anderson Cancer Center |
2004-12-21 | PHASE1 |
| NCT01430351 | TERMINATED | Glioblastoma; Gliosarcoma; Supratentorial Glioblastoma |
M.D. Anderson Cancer Center |
2011-09-14 | PHASE1 |
| NCT03519412 | COMPLETED | Colorectal Neoplasms; Microsatellite Instability |
IFOM ETS - The AIRC Institute of Molecular Oncology |
2019-01-23 | PHASE2 |
| NCT04477200 | ACTIVE_NOT_RECRUITING | Recurrent Glioblastoma; Recurrent Gliosarcoma; Recurrent Astrocytoma, Grade IV; Newly Diagnosed Glioblastoma; Newly Diagnosed Gliosarcoma; Newly Diagnosed Astrocytoma, Grade IV |
University of Michigan Rogel Cancer Center |
2020-08-05 | PHASE1 |
| NCT04893785 | RECRUITING | Lung Neuroendocrine Neoplasm; GEP Neuroendocrine Tumor |
National Cancer Institute, Naples |
2021-06-15 | PHASE2 |
| NCT05554003 | RECRUITING | Neuroendocrine Tumors; Frailty; Chemotherapy Effect |
European Institute of Oncology |
2022-01-14 | PHASE2 |
| NCT05827770 | UNKNOWN | Melanoma Stage III |
Yong Chen |
2023-05-01 | PHASE2 |
| NCT04462965 | UNKNOWN | Mucosal Melanoma |
Peking University Cancer Hospital & Institute |
2020-05-30 | PHASE2 |
| NCT01858168 | COMPLETED | Ewing Sarcoma; Rhabdomyosarcoma |
Massachusetts General Hospital |
2013-07-01 | PHASE1 |
| NCT04984733 | COMPLETED | Adenocarcinoma - GEJ; Cancer of Esophagus |
University of Southampton |
2021-09-28 | PHASE2 |
| NCT03137888 | COMPLETED | Glioblastoma; Gliosarcoma |
Emory University |
2017-09-20 | PHASE2 |
| NCT03709680 | ACTIVE_NOT_RECRUITING | Ewing Sarcoma; Solid Tumors; Rhabdoid Tumor; Rhabdomyosarcoma; Neuroblastoma; Medulloblastoma; Diffuse Intrinsic Pontine Glioma |
Pfizer |
2019-05-24 | PHASE2 |
| NCT05432791 | ACTIVE_NOT_RECRUITING | Locally Advanced Uterine Corpus Leiomyosarcoma; Metastatic Uterine Corpus Leiomyosarcoma; Stage III Uterine Corpus Leiomyosarcoma AJCC v8; Stage IV Uterine Corpus Leiomyosarcoma AJCC v8; Unresectable Uterine Corpus Leiomyosarcoma |
National Cancer Institute (NCI) |
2023-03-30 | PHASE2; PHASE3 |
| NCT04525014 | TERMINATED | Brain Tumor, Recurrent; Brain Tumor, Pediatric; Central Nervous System Neoplasms; Unspecified Childhood Solid Tumor, Protocol Specific |
EpicentRx, Inc. |
2023-01-26 | PHASE1 |
| NCT02781792 | COMPLETED | Glioma; Glioblastoma Multiforme |
Washington University School of Medicine |
2016-08-11 | PHASE2 |
| NCT03197506 | ACTIVE_NOT_RECRUITING | Glioblastoma; Gliosarcoma; Supratentorial Glioblastoma |
Mayo Clinic |
2018-01-15 | PHASE2 |
| NCT04324840 | TERMINATED | Glioblastoma |
Celgene |
2020-07-10 | PHASE1 |
| NCT05128734 | Not yet recruiting | Breast Cancer Triple Negative |
AHS Cancer Control Alberta |
2024-07-01 | Phase 2 |
| NCT05589961 | UNKNOWN | Glioblastoma Multiforme |
The Second Hospital of Hebei Medical University |
2022-10 | EARLY_PHASE1 |
| NCT04195139 | ACTIVE_NOT_RECRUITING | Glioblastoma Multiforme |
University of Sydney |
2018-02-22 | PHASE2 |
| NCT05031975 | UNKNOWN | Colorectal Cancer |
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
2022-05-02 | PHASE2 |
| NCT06161974 | Not yet recruiting | High Grade Glioma|Astrocytoma|Astrocytoma Grade III|Astrocytoma Grade IV|Diffuse Intrinsic Pontine Glioma|WHO Grade III Glioma|WHO Grade IV Glioma|Metastatic Brain Tumor|Diffuse Midline Glioma H3 K27M-Mutant|Thalamus Tumor|Spinal Tumor|IDH1 Mutation|IDH1 R132|IDH1 R132C|IDH1 R132H|IDH1 R132S|IDH1 R132G|IDH1 R132L|Oligodendroglioma |
Rigel Pharmaceuticals|Nationwide Children''s Hospital |
2024-06 | Phase 2 |
| NCT04388475 | COMPLETED | Recurrent Malignant Glioma; Brain Glioblastoma |
Oblato, Inc. |
2020-06-12 | PHASE2 |
| NCT01591577 | COMPLETED | Newly Diagnosed Glioblastoma Multiforme |
Jonsson Comprehensive Cancer Center |
2012-12-07 | PHASE2 |
| NCT04968366 | COMPLETED | Glioblastoma Multiforme of Brain |
Beijing Tiantan Hospital |
2021-07-30 | PHASE1 |
| NCT07635173 | COMPLETED | Glioma; Glioblastomas (GBM); High Grade Gliomas |
Shenzhen Zhenxing Medical Technology Co., Ltd |
2022-09-19 | PHASE1 |
| NCT05694416 | UNKNOWN | MGMT-Unmethylated Glioblastoma |
Zhongnan Hospital |
2023-02-01 | PHASE2 |
| NCT03776071 | COMPLETED | Glioblastoma |
Denovo Biopharma LLC |
2020-12-16 | PHASE3 |
| NCT05447195 | UNKNOWN | Newly-diagnosed Glioblastoma |
CANbridge Life Sciences Ltd. |
2021-10-10 | PHASE2 |
| NCT04967690 | Not yet recruiting | Newly Diagnosed Glioblastoma |
Double Bond Pharmaceutical AB |
2024-01 | Phase 1 |
| NCT04842526 | UNKNOWN | Refractory or Recurrent Neuroblastoma in Children |
Tianjin Medical University Cancer Institute and Hospital |
2021-04-12 | PHASE2 |
| NCT03243461 | UNKNOWN | Glioblastoma WHO Grade IV; Diffuse Midline Glioma Histone 3 K27M WHO Grade IV; Anaplastic Astrocytoma WHO Grade III; Diffuse Intrinsic Pontine Glioma; Gliomatosis Cerebri |
University of Göttingen |
2018-07-17 | PHASE3 |
| NCT04583020 | UNKNOWN | Glioblastoma |
Peking Union Medical College Hospital |
2020-11-12 | PHASE2 |
| NCT04280848 | COMPLETED | Glioblastoma |
Centre Hospitalier Universitaire de Besancon |
2020-05-26 | PHASE2 |
| NCT03466450 | COMPLETED | Glioblastoma |
Grupo Español de Investigación en Neurooncología |
2018-03-15 | PHASE1; PHASE2 |
| NCT04931849 | WITHDRAWN | Thrombocytopenia |
University of Rochester |
2022-05-06 | EARLY_PHASE1 |
| NCT04532229 | UNKNOWN | Diffuse Intrinsic Pontine Glioma |
Biotech Pharmaceutical Co., Ltd. |
2021-04-03 | PHASE3 |
| NCT04200066 | WITHDRAWN | Glioblastoma; Brain Tumor |
University of Rochester |
2022-06-01 | PHASE1 |
| NCT02137759 | UNKNOWN | Glioblastoma Multiforme of Brain |
Emory University |
2014-05-07 | PHASE2 |
| NCT04421378 | TERMINATED | Glioblastoma Multiforme |
Karyopharm Therapeutics Inc |
2020-06-08 | PHASE1; PHASE2 |
| NCT03576612 | COMPLETED | Glioma, Malignant |
Candel Therapeutics, Inc. |
2018-02-27 | PHASE1 |
| NCT01236560 | COMPLETED | Brain Stem Glioma; Cerebral Astrocytoma; Childhood Cerebellar Anaplastic Astrocytoma; Childhood Cerebral Anaplastic Astrocytoma; Childhood Spinal Cord Neoplasm |
National Cancer Institute (NCI) |
2011-01-26 | PHASE2; PHASE3 |
| NCT03556384 | COMPLETED | Gastrointestinal Stromal Tumors; Sdh; GIST; Cancer |
Adam Burgoyne, MD, PhD |
2018-09-12 | PHASE2 |
| NCT05698524 | Recruiting | Recurrent High Grade Glioma|Anaplastic Astrocytoma|Anaplastic Oligodendroglioma|Glioblastoma|Gliosarcoma |
University of Nebraska|Xynomic Pharmaceuticals Inc. |
2023-06-26 | Phase 1 |
| NCT03150810 | COMPLETED | Locally Advanced or Metastatic Solid Tumors |
BeiGene |
2017-06-28 | PHASE1 |
| NCT04945148 | Not yet recruiting | Glioblastoma IDH-wildtype |
Hopital Foch|National Cancer Institute France |
2023-05 | Phase 2 |
| NCT03932981 | UNKNOWN | Adult Brainstem Glioma |
Assistance Publique - Hôpitaux de Paris |
2019-07-26 | PHASE2 |
| NCT05190315 | COMPLETED | Glioblastoma Multiforme |
Mohammed Milhem |
2022-01-28 | PHASE1 |
| NCT03535350 | ACTIVE_NOT_RECRUITING | Glioblastoma |
Case Comprehensive Cancer Center |
2018-08-24 | PHASE1 |
| NCT06105619 | ACTIVE_NOT_RECRUITING | Glioblastoma |
Beijing Pearl Biotechnology Limited Liability Company |
2018-10-08 | PHASE2; PHASE3 |
| NCT02313389 | UNKNOWN | Primary Central Nervous System Lymphoma |
Assistance Publique - Hôpitaux de Paris |
2015-09 | PHASE3 |
| NCT03581292 | ACTIVE_NOT_RECRUITING | Anaplastic Astrocytoma; Glioblastoma; Malignant Glioma |
National Cancer Institute (NCI) |
2018-11-06 | PHASE2 |
| NCT03522298 | COMPLETED | Glioblastoma, Adult |
Kazia Therapeutics Limited |
2018-05-15 | PHASE2 |
| NCT02206230 | COMPLETED | Glioblastoma |
AHS Cancer Control Alberta |
2014-09-25 | PHASE2 |
| NCT03687957 | ACTIVE_NOT_RECRUITING | Glioma |
Washington University School of Medicine |
2019-01-04 | PHASE1; PHASE2 |
| NCT03232424 | COMPLETED | Glioblastoma, Adult |
Hackensack Meridian Health |
2017-07-26 | PHASE1 |
| NCT03778541 | UNKNOWN | Brain Metastases; Chemotherapy; Radiotherapy |
Chinese Academy of Medical Sciences |
2018-12-03 | PHASE3 |
| NCT04388033 | UNKNOWN | Glioblastoma; Glioma; Neoplasms, Neuroepithelial; Neuroectodermal Tumors; Neoplasms; Neoplasms, Nerve Tissue; Vaccines; Immunologic Factors |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2020-12 | PHASE1; PHASE2 |
| NCT03405792 | ACTIVE_NOT_RECRUITING | Glioblastoma; Glioblastoma, WHO Grade IV |
University of Florida |
2018-02-23 | PHASE2 |
| NCT03741244 | UNKNOWN | Glioma |
The Second Hospital of Hebei Medical University |
2019-05-06 | PHASE2 |
| NCT04091503 | COMPLETED | Glioma, Malignant; Gliosarcoma; Astrocytoma of Brain |
Center Trials & Treatment Europe |
2019-12-20 | PHASE1 |
| NCT03425292 | COMPLETED | Newly Diagnosed High Grade Glioma |
Saint John's Cancer Institute |
2018-03-01 | PHASE1 |
| NCT03139916 | COMPLETED | Glioblastoma |
Massachusetts General Hospital |
2017-09-13 | PHASE2 |
| NCT03345095 | COMPLETED | Newly Diagnosed Glioblastoma |
European Organisation for Research and Treatment of Cancer - EORTC |
2018-07-26 | PHASE3 |
| NCT03778294 | COMPLETED | Glioblastoma; Malignant Glioma |
Mayo Clinic |
2019-03-28 | PHASE2 |
| NCT03554473 | COMPLETED | Carcinoma, Small Cell; Lung Cancer; Small Cell Lung Cancer |
National Cancer Institute (NCI) |
2018-09-11 | PHASE1; PHASE2 |
| NCT03224104 | COMPLETED | Astrocytoma, Grade III; Glioblastoma |
European Organisation for Research and Treatment of Cancer - EORTC |
2018-06-12 | PHASE1 |
| NCT04541407 | COMPLETED | Non Small Cell Lung Cancer; CNS Progression |
University of Colorado, Denver |
2020-10-29 | PHASE1 |
| NCT02573324 | COMPLETED | Glioblastoma; Gliosarcoma |
AbbVie |
2015-01-04 | PHASE3 |
| NCT02975882 | COMPLETED | Childhood Solid Neoplasm; Recurrent Malignant Solid Neoplasm; Recurrent Primary Central Nervous System Neoplasm; Refractory Malignant Solid Neoplasm; Refractory Primary Central Nervous System Neoplasm |
Children's Oncology Group |
2017-08-15 | PHASE1 |
| NCT02659800 | TERMINATED | Lymphopenia; Malignant Glioma |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2018-10-30 | PHASE1 |
| NCT03387592 | TERMINATED | Neuroendocrine Carcinoma |
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS |
2017-03-06 | PHASE2 |
| NCT02661282 | COMPLETED | Cytomegalovirus Positive; Glioblastoma; Gliosarcoma; Malignant Glioma; Recurrent Brain Neoplasm; Recurrent Glioblastoma |
M.D. Anderson Cancer Center |
2016-06-01 | PHASE1; PHASE2 |
| NCT03732482 | UNKNOWN | Non Small Cell Lung Cancer Metastatic |
Taizhou Hospital |
2019-03-01 | PHASE2; PHASE3 |
| NCT03495921 | TERMINATED | Ewing Sarcoma; Ewing Family of Tumors; Ewing's Tumor Metastatic; Ewing's Sarcoma Metastatic; Ewing's Tumor Recurrent; Rare Diseases; Sarcoma; Neoplasms, Connective and Soft Tissue; Neoplasms by Histologic Type; Neoplasms, Bone Tissue; Neoplasms, Connective Tissue; Sarcoma, Ewing; Neoplasms |
Gradalis, Inc. |
2018-08-21 | PHASE3 |
| NCT04166435 | COMPLETED | Colorectal Cancer |
Yale University |
2020-06-17 | PHASE2 |
| NCT03763422 | TERMINATED | Low-grade Glioma; Temozolomide; Phase III; Wait or Treat |
European Organisation for Research and Treatment of Cancer - EORTC |
2020-03-16 | PHASE3 |
| NCT04467346 | COMPLETED | Therapeutic Equivalency |
Orphelia Pharma |
2020-09-25 | PHASE1 |
| NCT03796507 | WITHDRAWN | Glioma of Brain |
University of Rochester |
2021-09-01 | EARLY_PHASE1 |
| NCT03344250 | COMPLETED | Glioblastoma; Glioblastoma Multiforme |
University of Virginia |
2018-03-01 | PHASE1 |
| NCT02780024 | ACTIVE_NOT_RECRUITING | Glioblastoma Multiforme |
McGill University Health Centre/Research Institute of the McGill University Health Centre |
2015-03 | PHASE2 |
| NCT03426891 | COMPLETED | Glioblastoma; Brain Tumor; GBM |
H. Lee Moffitt Cancer Center and Research Institute |
2018-03-16 | PHASE1 |
| NCT03832621 | COMPLETED | Metastatic Colorectal Cancer |
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
2019-03-25 | PHASE2 |
| NCT02308527 | COMPLETED | Neuroblastoma |
University of Birmingham |
2013-07 | PHASE2 |
| NCT04194125 | UNKNOWN | Neuroendocrine Tumors |
University of Warmia and Mazury |
2019-02-01 | PHASE2 |
| NCT03190967 | TERMINATED | Breast Cancer; Brain Metastasis; Brain Cancer |
National Cancer Institute (NCI) |
2018-04-18 | PHASE1; PHASE2 |
| NCT03463733 | UNKNOWN | Glioma; Glioblastoma |
M.E. van Linde |
2018-03-02 | PHASE1 |
| NCT03480867 | WITHDRAWN | Glioblastoma Multiforme, Adult |
McGill University Health Centre/Research Institute of the McGill University Health Centre |
2017-03 | PHASE1 |
| NCT02596828 | COMPLETED | Pineoblastoma |
University of Regensburg |
2016-04 | PHASE2 |
| NCT03150862 | COMPLETED | Brain and Central Nervous System Tumors |
BeiGene USA, Inc. |
2017-07-24 | PHASE1; PHASE2 |
| NCT03869242 | UNKNOWN | Glioblastoma |
Tel-Aviv Sourasky Medical Center |
2018-10-01 | |
| NCT03879811 | WITHDRAWN | Colorectal Cancer |
Memorial Sloan Kettering Cancer Center |
2019-03-13 | PHASE2 |
| NCT02903069 | COMPLETED | Glioblastoma; Malignant Glioma |
Celgene |
2016-08-17 | PHASE1 |
| NCT02044120 | COMPLETED | Ewing Sarcoma |
Sarcoma Alliance for Research through Collaboration |
2014-05 | PHASE1 |
| NCT03587038 | ACTIVE_NOT_RECRUITING | Glioblastoma |
University of Oklahoma |
2018-09-03 | PHASE1 |
| NCT01269424 | COMPLETED | Glioblastoma Multiforme |
Stanton Gerson MD |
2011-11-22 | PHASE1 |
| NCT02943733 | TERMINATED | Neuroendocrine Tumors; Neoplasms; Cancer; Tumors |
University of Wisconsin, Madison |
2017-08-22 | PHASE1 |
| NCT03393000 | TERMINATED | Glioblastoma |
Diffusion Pharmaceuticals Inc |
2018-01-16 | PHASE3 |
| NCT02366728 | COMPLETED | Glioblastoma; Astrocytoma, Grade IV; Giant Cell Glioblastoma; Glioblastoma Multiforme |
Mustafa Khasraw, MBChB, MD, FRCP, FRACP |
2015-10-12 | PHASE2 |
| NCT02270034 | COMPLETED | Glioblastoma Multiforme (Grade IV) of Cerebellum |
Grupo Español de Investigación en Neurooncología |
2014-08-13 | PHASE1 |
| NCT02025881 | TERMINATED | High-risk Medulloblastoma |
Gustave Roussy, Cancer Campus, Grand Paris |
2013-09-14 | PHASE1; PHASE2 |
| NCT01467986 | COMPLETED | Neuroblastoma Recurrent |
University of Regensburg |
2013-08 | PHASE2 |
| NCT02590263 | COMPLETED | Malignant Glioma; Glioblastoma Multiforme |
AbbVie |
2015-08-24 | PHASE1; PHASE2 |
| NCT02942264 | TERMINATED | Brain Tumor; Astrocytoma; Astroglioma; Glioblastoma; Gliosarcoma |
National Cancer Institute (NCI) |
2016-12-14 | PHASE1; PHASE2 |
| NCT03904628 | UNKNOWN | High-grade Gliomas |
Lee's Pharmaceutical Limited |
2019-03-22 | PHASE1 |
| NCT02507232 | TERMINATED | Glioma |
Santosh Kesari |
2017-04-17 | EARLY_PHASE1 |
| NCT02343549 | TERMINATED | Cancer of Brain and Nervous System |
Wake Forest University Health Sciences |
2015-01 | PHASE2 |
| NCT03867123 | COMPLETED | Glioblastoma (GBM) |
Laminar Pharmaceuticals |
2018-12-04 | PHASE1 |
| NCT02864368 | TERMINATED | Glioblastoma; Glioblastoma Multiforme |
Eric Thompson, M.D. |
2016-12-07 | PHASE1 |
| NCT02330991 | COMPLETED | Glioblastoma |
Beijing Sanbo Brain Hospital |
2015-01 | PHASE2 |
| NCT02805179 | COMPLETED | Glioma |
University of Michigan Rogel Cancer Center |
2016-09-22 | PHASE2 |
| NCT02193347 | COMPLETED | Brain Cancer; Brain Neoplasm, Primary; Brain Neoplasms, Recurrent; Brain Tumor; Cancer of the Brain |
Katy Peters, MD, PhD |
2016-01-28 | PHASE1 |
| NCT00555399 | TERMINATED | Glioblastoma Multiforme; Anaplastic Glioma |
M.D. Anderson Cancer Center |
2007-11-28 | PHASE1; PHASE2 |
| NCT02758366 | TERMINATED | Glioblastoma (GBM); DIPG; Brainstem Glioma, Pediatric; Diffuse Spinal Glioma; Bilateral Thalamic Glioma; Gliomatosis Cerebri; Anaplastic Astrocytoma; Midline Diffuse Glioma |
Meyer Children's Hospital IRCCS |
2016-02 | PHASE2 |
| NCT04790097 | COMPLETED | Glioblastoma Multiforme |
Prof. Franciszek Lukaszczyk Memorial Oncology Center |
2017-02-21 | |
| NCT01700569 | TERMINATED | Grade IV Astrocytoma; Glioblastoma |
Institut Cancerologie de l'Ouest |
2013-01 | PHASE1 |
| NCT02799238 | COMPLETED | Glioblastoma |
CytoVac A/S |
2016-03 | PHASE2 |
| NCT01740258 | COMPLETED | Malignant Glioma; Grade 4 Malignant Glioma; Glioblastoma; Gliosarcoma |
Duke University |
2013-01 | PHASE2 |
| NCT03139331 | COMPLETED | Sarcoma; Refractory Sarcoma |
University of California, San Francisco |
2017-06-06 | PHASE1 |
| NCT02871843 | COMPLETED | Glioblastoma; Oligodendroglioma; Anaplastic Oligodendroglioma |
EpicentRx, Inc. |
2017-02-14 | PHASE1 |
| NCT02049593 | COMPLETED | Metastatic Cancer; Unspecified Adult Solid Tumor |
Jonsson Comprehensive Cancer Center |
2014-06-12 | PHASE1 |
| NCT01528046 | COMPLETED | Solid Tumors; Primary Brain Tumors |
H. Lee Moffitt Cancer Center and Research Institute |
2012-09-24 | PHASE1 |
| NCT03279601 | UNKNOWN | Neuroendocrine Tumors |
Peking University |
2017-09-01 | PHASE2 |
| NCT02364206 | COMPLETED | Adult Glioblastoma |
Centre Jean Perrin |
2015-06-08 | PHASE1; PHASE2 |
| NCT02209948 | COMPLETED | Glioblastoma |
Grupo Español de Investigación en Neurooncología |
2014-08-22 | PHASE2 |
| NCT03149575 | TERMINATED | Glioblastoma Multiforme; Glioblastoma; Glioma; GBM; Brain Cancer |
DelMar Pharmaceuticals, Inc. |
2017-10-27 | PHASE3 |
| NCT02414165 | TERMINATED | Glioblastoma Multiforme; Anaplastic Astrocytoma |
Tocagen Inc. |
2015-11-30 | PHASE2; PHASE3 |
| NCT03246113 | TERMINATED | Glioblastoma |
New York State Psychiatric Institute |
2018-03-19 | PHASE1 |
| NCT02209428 | UNKNOWN | Astrocytoma; Oligodendroglioma; Oligoastrocytoma |
Huashan Hospital |
2014-06 | PHASE2 |
| NCT01987830 | COMPLETED | Recurrent Glioblastoma |
Massachusetts General Hospital |
2013-11 | |
| NCT02392793 | COMPLETED | Childhood Solid Tumors |
St. Jude Children's Research Hospital |
2015-03-25 | PHASE1 |
| NCT02934204 | UNKNOWN | Primary CNS Lymphoma |
Guangdong Provincial People's Hospital |
2016-02 | PHASE2 |
| NCT03422445 | UNKNOWN | Advanced Melanoma |
Peking University Cancer Hospital & Institute |
2018-01-08 | PHASE2 |
| NCT02010606 | COMPLETED | Glioblastoma; Glioblastoma Multiforme; Glioma; Astrocytoma; Brain Tumor |
Cedars-Sinai Medical Center |
2014-01-08 | PHASE1 |
| NCT02378532 | COMPLETED | Glioblastoma Multiforme |
Maastricht Radiation Oncology |
2016-08 | PHASE1 |
| NCT02511132 | COMPLETED | Ewing's Sarcoma |
Gradalis, Inc. |
2016-02-10 | PHASE2 |
| NCT01114555 | COMPLETED | Neuroblastoma |
Memorial Sloan Kettering Cancer Center |
2010-04-29 | PHASE2 |
| NCT00826241 | COMPLETED | Brain Tumors; Spinal Cord Tumors |
National Institutes of Health Clinical Center (CC) |
2009-01 | PHASE2 |
| NCT03034135 | COMPLETED | Recurrent Glioblastoma |
Cantex Pharmaceuticals |
2017-03-09 | PHASE2 |
| NCT00669669 | TERMINATED | Glioblastoma; Gliosarcoma |
Fred Hutchinson Cancer Center |
2009-02-25 | PHASE1; PHASE2 |
| NCT01767194 | COMPLETED | Ganglioneuroblastoma; Recurrent Neuroblastoma |
National Cancer Institute (NCI) |
2013-02-12 | PHASE2 |
| NCT03168919 | TERMINATED | Glioma |
University of Alabama at Birmingham |
2016-10-06 | |
| NCT01355445 | COMPLETED | RHABDOMYOSARCOMA |
Centre Oscar Lambret |
2012-01 | PHASE2 |
| NCT02263105 | COMPLETED | High-grade Gliomas |
Huashan Hospital |
2014-10 | PHASE2 |
| NCT01514201 | COMPLETED | Anaplastic Astrocytoma; Brain Stem Glioma; Childhood Mixed Glioma; Fibrillary Astrocytoma; Giant Cell Glioblastoma; Glioblastoma; Gliosarcoma; Untreated Childhood Anaplastic Astrocytoma; Untreated Childhood Brain Stem Glioma; Untreated Childhood Fibrillary Astrocytoma; Untreated Childhood Giant Cell Glioblastoma; Untreated Childhood Glioblastoma; Untreated Childhood Gliosarcoma |
National Cancer Institute (NCI) |
2012-02-01 | PHASE1; PHASE2 |
| NCT02976441 | WITHDRAWN | Astrocytoma; Brainstem Glioma; Ependymoma; Mixed Glioma; Oligodendroglioma; Optic Nerve Glioma |
Washington University School of Medicine |
2017-01 | EARLY_PHASE1 |
| NCT01005472 | COMPLETED | Metastatic Melanoma |
Jonsson Comprehensive Cancer Center |
2008-12-01 | PHASE1 |
| NCT02477813 | TERMINATED | Small Cell Lung Cancer Recurrent |
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS |
2015-01 | PHASE2 |
| NCT02766270 | UNKNOWN | Grade II/III Glioma |
Beijing Tiantan Hospital |
2016-09-26 | EARLY_PHASE1 |
| NCT01765088 | UNKNOWN | Anaplastic Oligoastrocytoma; Anaplastic Astrocytoma; Glioblastoma |
Sun Yat-sen University |
2012-09 | PHASE3 |
| NCT01180816 | COMPLETED | Glioblastoma Multiforme; Anaplastic Astrocytoma |
Northwell Health |
2010-08 | PHASE1 |
| NCT01020292 | COMPLETED | Glioma |
Abramson Cancer Center at Penn Medicine |
2009-04 | PHASE1 |
| NCT03204019 | UNKNOWN | Pancreatic Neuroendocrine Tumor |
Chinese Academy of Medical Sciences |
2016-10 | PHASE2 |
| NCT02189109 | COMPLETED | Glioblastoma Multiforme |
NuvOx LLC |
2014-05 | PHASE1 |
| NCT01235793 | TERMINATED | B-Cell Lymphoma Originating in the CNS |
Cedars-Sinai Medical Center |
2010-10-14 | PHASE2 |
| NCT01390571 | COMPLETED | Brain and Central Nervous System Tumors |
Cancer Research UK |
2011-07 | PHASE1 |
| NCT02832635 | UNKNOWN | Brain Metastasis; Radiation Therapy Complication |
Sun Yat-sen University |
2016-07 | PHASE2 |
| NCT01450826 | COMPLETED | Nausea; Vomiting; Glioma |
Katy Peters |
2014-06-24 | PHASE2 |
| NCT01149109 | COMPLETED | Glioblastoma |
University Hospital, Bonn |
2010-10 | PHASE3 |
| NCT00782756 | COMPLETED | Brain Cancer; Malignant Glioma |
Memorial Sloan Kettering Cancer Center |
2008-10-28 | PHASE2 |
| NCT02272270 | COMPLETED | Newly Diagnosed High Grade Glioma |
University of Utah |
2014-10-27 | PHASE1 |
| NCT02395692 | TERMINATED | Adult Brain Glioblastoma |
National Cancer Institute (NCI) |
2015-12-18 | PHASE2 |
| NCT02510950 | TERMINATED | Glioblastoma Multiforme; Astrocytoma, Grade IV |
Washington University School of Medicine |
2015-12-03 | PHASE1 |
| NCT01860638 | COMPLETED | Glioblastoma |
Hoffmann-La Roche |
2013-08-19 | PHASE2 |
| NCT01638546 | ACTIVE_NOT_RECRUITING | Recurrent Lung Small Cell Carcinoma |
National Cancer Institute (NCI) |
2012-07-27 | PHASE2 |
| NCT02029573 | COMPLETED | Glioblastoma Multiforme |
King Fahad Medical City |
2014-01-01 | PHASE2 |
| NCT01866449 | COMPLETED | Glioblastoma Multiforme (GBM) WHO Grade IV |
University of Ulm |
2013-10 | PHASE2 |
| NCT02681705 | UNKNOWN | Medulloblastoma |
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine |
2010-01 | PHASE2 |
| NCT02231762 | COMPLETED | Gastroenteropancreatic Neuroendocrine Tumors |
Ipsen |
2014-10 | PHASE2 |
| NCT01260103 | WITHDRAWN | Optic Nerve Glioma |
Burzynski Research Institute |
2011-12 | PHASE3 |
| NCT00068250 | COMPLETED | Brain and Central Nervous System Tumors; Lymphoma |
Radiation Therapy Oncology Group |
2003-07 | PHASE1; PHASE2 |
| NCT01845675 | COMPLETED | Advanced Well-differentiated Pancreatic Neuroendocrine Tumor |
Peking Union Medical College Hospital |
2013-04 | PHASE2 |
| NCT01480479 | COMPLETED | Glioblastoma; Small Cell Glioblastoma; Giant Cell Glioblastoma; Gliosarcoma; Glioblastoma With Oligodendroglial Component |
Celldex Therapeutics |
2011-11 | PHASE3 |
| NCT01835145 | COMPLETED | Recurrent Uveal Melanoma; Stage III Uveal Melanoma AJCC v7; Stage IIIA Uveal Melanoma AJCC v7; Stage IIIB Uveal Melanoma AJCC v7; Stage IIIC Uveal Melanoma AJCC v7; Stage IV Uveal Melanoma AJCC v7 |
National Cancer Institute (NCI) |
2013-07-31 | PHASE2 |
| NCT01708174 | COMPLETED | Medulloblastoma |
Novartis Pharmaceuticals |
2013-05-06 | PHASE2 |
| NCT02254954 | TERMINATED | Glioblastoma |
Actelion |
2015-01-08 | PHASE1 |
| NCT01543464 | TERMINATED | Malignant Melanoma |
Inge Marie Svane |
2012-05 | PHASE2 |
| NCT01729260 | COMPLETED | Newly Diagnosed High-Grade Glioma |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2013-04-04 | PHASE1 |
| NCT00626483 | COMPLETED | Malignant Neoplasms Brain |
Gary Archer Ph.D. |
2007-04-24 | PHASE1 |
| NCT00792012 | COMPLETED | Glioblastoma Multiforme |
University of Colorado, Denver |
2005-11 | PHASE1 |
| NCT01055314 | COMPLETED | Adult Rhabdomyosarcoma; Childhood Alveolar Rhabdomyosarcoma; Childhood Embryonal Rhabdomyosarcoma; Metastatic Childhood Soft Tissue Sarcoma; Stage IV Adult Soft Tissue Sarcoma; Untreated Childhood Rhabdomyosarcoma |
National Cancer Institute (NCI) |
2010-01 | PHASE2 |
| NCT01812616 | COMPLETED | Cancer |
Jazz Pharmaceuticals |
2014-09 | PHASE1; PHASE2 |
| NCT00525031 | COMPLETED | Melanoma |
M.D. Anderson Cancer Center |
2006-08 | PHASE2 |
| NCT02530502 | TERMINATED | Adult Glioblastoma |
Northwestern University |
2015-09-30 | PHASE1 |
| NCT01435395 | COMPLETED | Glioblastoma Multiforme |
Emory University |
2011-12 | PHASE1 |
| NCT01920191 | COMPLETED | CNS Tumor, Adult |
University Hospital, Geneva |
2013-08 | PHASE1; PHASE2 |
| NCT00974987 | COMPLETED | Brain and Central Nervous System Tumors |
Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan |
2009-09-01 | PHASE2 |
| NCT01390948 | COMPLETED | High Grade Glioma |
Hoffmann-La Roche |
2011-10-18 | PHASE2 |
| NCT02113007 | TERMINATED | Primary Central Nervous System Lymphoma |
SCRI Development Innovations, LLC |
2014-07 | PHASE2 |
| NCT01900951 | UNKNOWN | Carcinoma, Small Cell |
Chinese PLA General Hospital |
2013-01 | PHASE2 |
| NCT02389738 | COMPLETED | Blood Brain Barrier Defect |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2015-02 | EARLY_PHASE1 |
| NCT00804908 | COMPLETED | Melanoma; Metastatic Melanoma; Skin Cancer |
AbbVie (prior sponsor, Abbott) |
2009-02 | PHASE2 |
| NCT02039778 | TERMINATED | Glioblastoma; Malignant Glioma; Brain Tumors; Anaplastic Astrocytoma |
Beth Israel Medical Center |
2013-12 | |
| NCT01752491 | COMPLETED | Glioblastoma; GBM; Glioblastoma Multiforme |
Joseph J. Cullen, MD, FACS |
2013-04-01 | PHASE1 |
| NCT01704287 | COMPLETED | Malignant Melanoma |
Merck Sharp & Dohme LLC |
2012-11-20 | PHASE2 |
| NCT01465347 | COMPLETED | Glioblastoma; GBM; Glioma |
Diffusion Pharmaceuticals Inc |
2012-02 | PHASE1; PHASE2 |
| NCT01847235 | COMPLETED | Anaplastic Oligodendroglioma; Anaplastic Oligoastrocytoma |
Seoul National University Hospital |
2013-05 | PHASE2 |
| NCT00876993 | COMPLETED | Central Nervous System Tumors |
Johns Hopkins All Children's Hospital |
2008-09 | PHASE1 |
| NCT02168270 | TERMINATED | Anaplastic Astrocytoma; Anaplastic Oligodendroglioma; Anaplastic Oligoastrocytoma; Glioblastoma; Gliosarcoma |
University of Nebraska |
2014-06-16 | PHASE1 |
| NCT01946529 | COMPLETED | Desmoplastic Small Round Cell Tumor; Ewing Sarcoma of Bone or Soft Tissue; Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor |
St. Jude Children's Research Hospital |
2013-12-27 | PHASE2 |
| NCT02092038 | COMPLETED | Glioblastoma |
Tampa General Hospital |
2014-11 | PHASE1 |
| NCT01590082 | TERMINATED | Melanoma |
M.D. Anderson Cancer Center |
2012-11 | PHASE1; PHASE2 |
| NCT01618136 | COMPLETED | Malignant Solid Tumour; Ovarian Cancer; Triple Negative Breast Cancer; Advanced Melanoma; B-cell Malignancy, Low-grade |
Eisai Limited |
2012-01 | PHASE1; PHASE2 |
| NCT00539591 | ACTIVE_NOT_RECRUITING | Malignant Melanoma |
St. Jude Children's Research Hospital |
2008-05-09 | PHASE2 |
| NCT01213407 | COMPLETED | Glioblastoma Multiforme |
Activartis Biotech |
2010-04 | PHASE2 |
| NCT02085304 | TERMINATED | Glioblastoma |
St. Joseph's Hospital and Medical Center, Phoenix |
2013-05-07 | PHASE1; PHASE2 |
| NCT00715793 | COMPLETED | Malignant Melanoma |
Hussein Tawbi |
2008-06 | PHASE1; PHASE2 |
| NCT01830101 | WITHDRAWN | Recurrent Glioblastoma |
AHS Cancer Control Alberta |
2014-02 | PHASE3 |
| NCT00004259 | COMPLETED | Brain and Central Nervous System Tumors |
Radiation Therapy Oncology Group |
2000-06 | PHASE3 |
| NCT02065466 | WITHDRAWN | Metastatic Melanoma; Brain Metastases |
University of Arizona |
2014-07 | PHASE1; PHASE2 |
| NCT01222221 | COMPLETED | Brain and Central Nervous System Tumors |
Cancer Research UK |
2010-07 | PHASE1 |
| NCT01534845 | UNKNOWN | Anaplastic Glioma of Brain; Loss of Chromosomes 1p/19q |
Jong Hoon Kim |
2012-03 | PHASE2 |
| NCT00749723 | COMPLETED | Recurrent Brain Tumors; Supratentorial PNETs; Medulloblastomas; Ependymomas |
University Hospital, Bonn |
2006-02-01 | PHASE2; PHASE3 |
| NCT01505608 | TERMINATED | Neuroblastoma |
Giselle Sholler |
2011-12 | PHASE1; PHASE2 |
| NCT01702610 | COMPLETED | Glioblastoma Mutliforme |
McGill University Health Centre/Research Institute of the McGill University Health Centre |
2008-12 | |
| NCT00883298 | COMPLETED | Recurrent Glioblastoma Multiforme; Recurrent Gliosarcoma |
Center for Neurosciences, Tucson |
2009-04 | PHASE2 |
| NCT01736800 | WITHDRAWN | Central Nervous System (CNS) Metastases; Brain Metastases |
The Methodist Hospital Research Institute |
2007-03 | PHASE2 |
| NCT00925132 | TERMINATED | Metastatic Melanoma |
University of Iowa |
2009-12 | PHASE1; PHASE2 |
| NCT00890786 | COMPLETED | Newly Diagnosed High-Grade Gliomas; Diffuse Intrinsic Pontine Glioma |
Children's Hospital Medical Center, Cincinnati |
2009-05 | EARLY_PHASE1 |
| NCT00313729 | COMPLETED | CNS Tumor, Adult |
University of California, San Francisco |
1999-05 | PHASE2 |
| NCT01209442 | COMPLETED | Glioblastoma Multiforme |
University of Colorado, Denver |
2010-09-16 | PHASE2 |
| NCT01781403 | COMPLETED | Rectal Cancer |
Asan Medical Center |
2013-05-10 | PHASE1 |
| NCT00967330 | COMPLETED | Glioblastoma Multiforme |
Hoffmann-La Roche |
2010-06 | PHASE2 |
| NCT01952886 | WITHDRAWN | Malignant Glioma |
Duke University |
PHASE2 | |
| NCT01670890 | UNKNOWN | Malignant Gliomas |
Peking Union Medical College Hospital |
2012-08 | PHASE2 |
| NCT02223884 | COMPLETED | Malignant Melanoma |
Yonsei University |
2011-07 | PHASE2 |
| NCT01110876 | TERMINATED | Brain Cancer; Glioblastoma Multiforme |
M.D. Anderson Cancer Center |
2011-06 | PHASE1; PHASE2 |
| NCT01313884 | TERMINATED | Bone Cancer; Ewing's Sarcoma |
Stanford University |
2011-05 | PHASE2 |
| NCT00905060 | COMPLETED | Brain and Central Nervous System Tumors |
University of California, San Francisco |
2009-06-29 | PHASE2 |
| NCT01026493 | COMPLETED | Brain and Central Nervous System Tumors |
Radiation Therapy Oncology Group |
2010-07 | PHASE1; PHASE2 |
| NCT00662506 | COMPLETED | Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma |
National Cancer Institute (NCI) |
2008-04 | PHASE1; PHASE2 |
| NCT01105702 | TERMINATED | Brain Cancer |
NYU Langone Health |
2010-05 | PHASE2 |
| NCT01517776 | TERMINATED | Gliomas |
Martin-Luther-Universität Halle-Wittenberg |
2012-01 | PHASE2 |
| NCT01605162 | TERMINATED | Wild Type BRAF Stage IV Melanoma; Unresectable Stage III Melanoma |
Eisai Inc. |
2012-05 | PHASE2 |
| NCT01019434 | COMPLETED | Brain and Central Nervous System Tumors |
European Organisation for Research and Treatment of Cancer - EORTC |
2009-10 | PHASE2 |
| NCT00498927 | COMPLETED | Brain and Central Nervous System Tumors |
Memorial Sloan Kettering Cancer Center |
2007-06 | PHASE2 |
| NCT01141244 | COMPLETED | Unspecified Childhood Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2010-06 | PHASE1 |
| NCT01014767 | TERMINATED | Brain Cancer; Choroid Plexus Tumors |
Tufts Medical Center |
2009-11 | PHASE3 |
| NCT02343081 | COMPLETED | Brain Neoplasms, Malignant, Primary |
Monte Verde SA |
2012-01 | PHASE4 |
| NCT00918320 | COMPLETED | Neuroblastoma; Brain Tumors; Solid Tumors |
Gustave Roussy, Cancer Campus, Grand Paris |
2009-06 | PHASE2 |
| NCT01102595 | COMPLETED | Glioblastomas |
Grupo Español de Investigación en Neurooncología |
2009-12 | PHASE2 |
| NCT00441142 | COMPLETED | Glioblastoma Multiforme; Gliosarcoma |
Patrick Y. Wen, MD |
2007-05-25 | PHASE1; PHASE2 |
| NCT00615186 | TERMINATED | Glioblastoma Multiforme |
Bradmer Pharmaceuticals Inc. |
2008-06 | PHASE3 |
| NCT00895960 | TERMINATED | Glioblastoma; CNS Disease; Brain Diseases |
M.D. Anderson Cancer Center |
2009-05-07 | PHASE1 |
| NCT01328535 | COMPLETED | Recurrent Melanoma; Stage IV Melanoma |
Mayo Clinic |
2011-01 | PHASE2 |
| NCT00486603 | COMPLETED | Brain and Central Nervous System Tumors |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2007-10-29 | PHASE1; PHASE2 |
| NCT01119599 | COMPLETED | Acoustic Schwannoma; Adult Anaplastic (Malignant) Meningioma; Adult Anaplastic Astrocytoma; Adult Anaplastic Ependymoma; Adult Brain Stem Glioma; Adult Choroid Plexus Neoplasm; Adult Craniopharyngioma; Adult Diffuse Astrocytoma; Adult Ependymoblastoma; Adult Ependymoma; Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma; Adult Grade I Meningioma; Adult Grade II Meningioma; Adult Medulloblastoma; Adult Mixed Glioma; Adult Myxopapillary Ependymoma; Adult Oligodendroglioma; Adult Papillary Meningioma; Adult Pilocytic Astrocytoma; Adult Pineal Gland Astrocytoma; Adult Pineoblastoma; Adult Pineocytoma; Adult Primary Melanocytic Lesion of Meninges; Adult Subependymal Giant Cell Astrocytoma; Adult Subependymoma; Adult Supratentorial Primitive Neuroectodermal Tumor; Malignant Adult Intracranial Hemangiopericytoma |
National Cancer Institute (NCI) |
2010-05 | PHASE1 |
| NCT01051596 | COMPLETED | Colorectal Cancer |
Georgetown University |
2009-09 | PHASE2 |
| NCT00302159 | COMPLETED | High Grade Gliomas; Brain Tumors |
National Cancer Institute (NCI) |
2006-03 | PHASE2 |
| NCT00525525 | COMPLETED | Glioblastoma; Gliosarcoma |
University of California, San Francisco |
2007-09 | PHASE2 |
| NCT02898012 | COMPLETED | Glioblastoma Multiforme; Primary Brain Tumor |
Assistance Publique - Hôpitaux de Paris |
2010-10 | PHASE2 |
| NCT01587144 | TERMINATED | Glioblastoma Multiforme |
Spectrum Pharmaceuticals, Inc |
2012-06-19 | PHASE2 |
| NCT01181193 | UNKNOWN | Glioblastoma Multiforme |
Soroka University Medical Center |
2011-03 | PHASE1; PHASE2 |
| NCT00740636 | COMPLETED | Lung Cancer |
Memorial Sloan Kettering Cancer Center |
2008-08 | PHASE2 |
| NCT00993044 | COMPLETED | Refractory Solid Tumors in Children |
Children's Hospital Los Angeles |
2009-09 | PHASE1 |
| NCT00114140 | COMPLETED | Brain and Central Nervous System Tumors |
Radiation Therapy Oncology Group |
2005-01 | PHASE2 |
| NCT00626015 | COMPLETED | Malignant Neoplasms of Brain |
John Sampson |
2007-03 | PHASE1 |
| NCT00694837 | COMPLETED | Glioblastoma |
Maastricht Radiation Oncology |
2009-03 | PHASE1 |
| NCT00811993 | TERMINATED | Neoplasms |
Hoffmann-La Roche |
2009-02 | PHASE1 |
| NCT00900757 | COMPLETED | Malignant Glioma |
Duke University |
2009-08 | PHASE2 |
| NCT00085254 | COMPLETED | Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma |
National Cancer Institute (NCI) |
2005-04 | PHASE1; PHASE2 |
| NCT01284335 | TERMINATED | Advanced Solid Tumors |
Eli Lilly and Company |
2008-07 | PHASE1 |
| NCT00248534 | TERMINATED | Lymphoma |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2005-09 | PHASE2 |
| NCT00639262 | COMPLETED | Brain Metastases; Primary Brain Tumors |
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University |
2008-03 | PHASE1 |
| NCT01009788 | COMPLETED | Breast Cancer; Metastatic Breast Cancer; BRCA1 Gene Mutation; brca2 Gene Mutation |
Steven J Isakoff, MD, PhD |
2009-11 | PHASE2 |
| NCT03310372 | COMPLETED | Glioblastoma Multiforme |
Central Hospital, Nancy, France |
2008-02-13 | PHASE2 |
| NCT00612339 | COMPLETED | Glioblastoma; Gliosarcoma |
Duke University |
2007-08 | PHASE2 |
| NCT00301067 | COMPLETED | Metastatic Melanoma |
Northwestern University |
2005-01-30 | PHASE1; PHASE2 |
| NCT00770471 | COMPLETED | Brain and Central Nervous System Tumors |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2009-07-13 | PHASE1 |
| NCT01285414 | COMPLETED | Glioblastoma Multiforme |
Myrexis Inc. |
2010-12 | PHASE2 |
| NCT00395070 | COMPLETED | Metastatic Melanoma |
Vical |
2006-10 | PHASE3 |
| NCT00527657 | COMPLETED | Brain Neoplasms; Melanoma |
M.D. Anderson Cancer Center |
2006-02-09 | PHASE1 |
| NCT00756106 | TERMINATED | Brain and Central Nervous System Tumors |
Massachusetts General Hospital |
2008-07 | |
| NCT00544284 | COMPLETED | Brain and Central Nervous System Tumors; Lymphoma; Metastatic Cancer; Unspecified Adult Solid Tumor, Protocol Specific |
City of Hope Medical Center |
2005-01 | PHASE1 |
| NCT00939991 | COMPLETED | Brain Tumor; Glioblastoma |
Katy Peters |
2009-10 | PHASE1; PHASE2 |
| NCT00553150 | COMPLETED | Brain and Central Nervous System Tumors |
Alliance for Clinical Trials in Oncology |
2009-03 | PHASE1; PHASE2 |
| NCT01043536 | COMPLETED | Glioblastoma |
Centre Georges Francois Leclerc |
2009-09 | PHASE1 |
| NCT00369590 | COMPLETED | Adult Anaplastic Astrocytoma; Adult Anaplastic Oligodendroglioma; Adult Giant Cell Glioblastoma; Adult Gliosarcoma; Recurrent Adult Brain Tumor |
National Cancer Institute (NCI) |
2006-08 | PHASE2 |
| NCT00619112 | COMPLETED | Recurrent Central Nervous System Neoplasm |
University of California, San Francisco |
2007-10 | PHASE2 |
| NCT00657267 | COMPLETED | Glioblastoma; Gliosarcoma |
Patrick Y. Wen, MD |
2008-05 | PHASE2 |
| NCT01193140 | COMPLETED | Solid Tumor Cancers |
Abbott |
2010-07 | PHASE2 |
| NCT00817284 | COMPLETED | Glioblastoma Multiforme |
Ulrik Lassen |
2008-11 | PHASE2 |
| NCT01044225 | TERMINATED | Glioblastoma |
Bart Neyns |
2009-09 | PHASE2 |
| NCT00385853 | COMPLETED | Glioblastoma |
Massachusetts General Hospital |
2006-09 | PHASE1 |
| NCT00867568 | COMPLETED | Neuroblastoma; Medulloblastoma; Relapse |
Giselle Sholler |
2009-03 | PHASE1 |
| NCT00597402 | COMPLETED | Glioblastoma; Gliosarcoma; Brain Tumor |
Duke University |
2007-07 | PHASE2 |
| NCT00915694 | TERMINATED | Brain and Central Nervous System Tumors |
Abramson Cancer Center at Penn Medicine |
2009-04 | PHASE1 |
| NCT01113463 | TERMINATED | Brain Cancer |
M.D. Anderson Cancer Center |
2010-04 | PHASE2 |
| NCT00614978 | COMPLETED | Metastatic Breast Cancer; Brain Metastases; HER2 Positive |
Jules Bordet Institute |
2008-01 | PHASE1 |
| NCT00763750 | COMPLETED | Brain Tumor |
howard safran |
2008-10 | PHASE2 |
| NCT01085422 | COMPLETED | Prostate Cancer |
AbbVie (prior sponsor, Abbott) |
2010-04 | PHASE1 |
| NCT00727506 | COMPLETED | Glioma |
Boehringer Ingelheim |
2008-07-14 | PHASE2 |
| NCT00820963 | COMPLETED | Brain and Central Nervous System Tumors |
Centre Leon Berard |
2006-07 | PHASE3 |
| NCT00667953 | TERMINATED | Melanoma; Advanced Melanoma |
Abramson Cancer Center at Penn Medicine |
2003-01 | PHASE1; PHASE2 |
| NCT00250211 | COMPLETED | Glioblastoma; Glioma |
AHS Cancer Control Alberta |
2005-03 | PHASE1; PHASE2 |
| NCT00249964 | COMPLETED | Lung Diseases; Cancer |
New Mexico Cancer Research Alliance |
2003-11 | PHASE1 |
| NCT01127178 | TERMINATED | Solid Tumors |
Eisai Inc. |
2010-03-29 | PHASE1 |
| NCT00632203 | TERMINATED | Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Carcinoma, Large Cell; Carcinoma, Squamous Cell |
Merck Sharp & Dohme LLC |
2008-03-04 | PHASE2 |
| NCT00404495 | COMPLETED | Glioma; Medulloblastoma |
Pfizer |
2007-04 | PHASE2 |
| NCT00643825 | UNKNOWN | Glioblastoma |
Cliniques universitaires Saint-Luc- Université Catholique de Louvain |
2008-01 | PHASE2 |
| NCT00717275 | TERMINATED | Brain Metastases |
University of Florida |
2008-09 | PHASE2 |
| NCT00960063 | TERMINATED | Neoplasms; Solid Tumors; Bone Cancer; Kidney Tumor; Neuroblastoma |
Merck Sharp & Dohme LLC |
2009-11-11 | PHASE1 |
| NCT00392886 | UNKNOWN | Brain and Central Nervous System Tumors |
Children's Hospital Los Angeles |
2004-03 | PHASE3 |
| NCT00316849 | COMPLETED | Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma |
National Cancer Institute (NCI) |
2006-05 | PHASE1 |
| NCT01458730 | COMPLETED | Central Nervous System Lymphoma |
University of Aarhus |
2007-05 | PHASE2 |
| NCT00768911 | UNKNOWN | Glioblastoma Multiforme |
Adnexus, A Bristol-Myers Squibb R&D Company |
2008-10 | PHASE1 |
| NCT00504660 | COMPLETED | Anaplastic Glioma of Brain; Glioblastoma Multiforme; Brain Cancer |
M.D. Anderson Cancer Center |
2003-09 | PHASE2 |
| NCT00503594 | UNKNOWN | Lymphoma |
Assistance Publique - Hôpitaux de Paris |
2007-07 | PHASE2 |
| NCT00626405 | COMPLETED | Melanoma (Skin) |
Alliance for Clinical Trials in Oncology |
2008-08 | PHASE2 |
| NCT01022918 | COMPLETED | Naive Unresectable Glioblastoma |
Centre Georges Francois Leclerc |
2009-01 | PHASE2 |
| NCT00638963 | TERMINATED | Breast Neoplasm; Brain Neoplasm; Second Neoplasm |
Merck Sharp & Dohme LLC |
2008-10-02 | PHASE2 |
| NCT00526617 | COMPLETED | Non-hematologic Malignancies; Metastatic Melanoma; Breast Cancer; Ovarian Cancer; Primary Peritoneal Cancer; Fallopian Tube Cancer; Hepatocellular Carcinoma |
AbbVie |
2007-08 | PHASE1 |
| NCT00098865 | COMPLETED | Central Nervous System Tumor, Pediatric; Neuroblastoma |
Dana-Farber Cancer Institute |
2002-09 | PHASE2 |
| NCT01242566 | COMPLETED | Primary Brain Tumor; Glioblastoma |
Assistance Publique - Hôpitaux de Paris |
2007-07 | PHASE2 |
| NCT00436436 | TERMINATED | Brain and Central Nervous System Tumors |
National Cancer Institute (NCI) |
2006-11-13 | PHASE2 |
| NCT00077207 | COMPLETED | Brain Tumor; Central Nervous System Tumor |
Children's Oncology Group |
2004-07 | |
| NCT00433381 | COMPLETED | Adult Glioblastoma; Adult Gliosarcoma; Recurrent Adult Brain Neoplasm |
National Cancer Institute (NCI) |
2007-03-01 | PHASE2 |
| NCT00424554 | COMPLETED | Glioma |
Merck Sharp & Dohme LLC |
2006-09-26 | PHASE2 |
| NCT00703859 | WITHDRAWN | Glioblastoma |
AHS Cancer Control Alberta |
2008-07 | PHASE1 |
| NCT00521001 | COMPLETED | Melanoma (Skin) |
Alliance for Clinical Trials in Oncology |
2008-01 | PHASE2 |
| NCT00402116 | COMPLETED | Glioblastoma; Glioblastoma Multiforme; Gliosarcoma |
Eli Lilly and Company |
2006-09 | PHASE1; PHASE2 |
| NCT00611247 | COMPLETED | Leukemia, Myeloid |
Bruno C. Medeiros |
2007-12 | PHASE2 |
| NCT00875355 | UNKNOWN | Breast Cancer; Metastatic Cancer |
Institut Curie |
2007-11 | PHASE2 |
| NCT00262730 | COMPLETED | Glioblastoma Multiforme |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2006-01 | PHASE2 |
| NCT00944801 | COMPLETED | Glioblastoma |
University of Regensburg |
2002-07 | PHASE1; PHASE2 |
| NCT04755023 | COMPLETED | Oligodendroglioma; Oligoastrocytoma |
Assistance Publique Hopitaux De Marseille |
2005-12-21 | PHASE2 |
| NCT00311584 | COMPLETED | Neuroblastoma |
Children's Oncology Group |
2006-04 | PHASE2 |
| NCT00575887 | COMPLETED | Glioblastoma; Astrocytoma; Oligodendroglioma; Brain Tumor, Recurrent |
Marmara University |
2006-08 | PHASE2 |
| NCT00720564 | COMPLETED | Brain and Central Nervous System Tumors |
City of Hope Medical Center |
2008-04 | PHASE1 |
| NCT00602576 | COMPLETED | Melanoma (Skin) |
Abramson Cancer Center at Penn Medicine |
2005-01-01 | PHASE2 |
| NCT00272870 | TERMINATED | Glioblastoma Multiforme (WHO Grade IV); Anaplastic Astrocytoma (WHO Grade III) |
Children's Hospital Medical Center, Cincinnati |
2005-12 | PHASE1 |
| NCT00508456 | TERMINATED | Glioblastoma Multiforme |
M.D. Anderson Cancer Center |
2004-08 | PHASE1 |
| NCT00516607 | UNKNOWN | Brain and Central Nervous System Tumors |
European Organisation for Research and Treatment of Cancer - EORTC |
2007-07 | PHASE1 |
| NCT00050986 | COMPLETED | Glioblastoma Multiforme |
M.D. Anderson Cancer Center |
2002-12 | PHASE1; PHASE2 |
| NCT00267592 | COMPLETED | Glioblastoma Multiforme |
Teva Branded Pharmaceutical Products R&D, Inc. |
2005-12 | PHASE2 |
| NCT00584883 | COMPLETED | Brain Tumor |
University of Alabama at Birmingham |
2003-08 | PHASE1 |
| NCT00724841 | TERMINATED | Metastatic Melanoma |
Gemin X |
2008-06 | PHASE1; PHASE2 |
| NCT00591370 | COMPLETED | Melanoma |
Memorial Sloan Kettering Cancer Center |
2005-01 | PHASE2 |
| NCT01364064 | COMPLETED | Glioblastoma |
King Faisal Specialist Hospital & Research Center |
2007-01 | PHASE3 |
| NCT00026494 | COMPLETED | Metastatic Cancer |
Memorial Sloan Kettering Cancer Center |
2001-07 | PHASE1; PHASE2 |
| NCT00376103 | TERMINATED | Glioblastoma Multiforme |
Methodist Healthcare - Memphis |
2006-08 | PHASE1; PHASE2 |
| NCT00400816 | COMPLETED | Central Nervous System Tumors; Brain Tumor |
The Cleveland Clinic |
2005-08 | PHASE2 |
| NCT00266812 | TERMINATED | Carcinoma, Non-Small-Cell Lung |
Merck Sharp & Dohme LLC |
2005-03-08 | PHASE2 |
| NCT00274833 | COMPLETED | CNS Tumor, Adult |
David Peereboom |
2005-10 | PHASE2 |
| NCT00338130 | COMPLETED | Melanoma |
AstraZeneca |
2006-07 | PHASE2 |
| NCT00616005 | COMPLETED | Glioblastoma |
Duke University |
2005-11 | PHASE2 |
| NCT00104988 | COMPLETED | Melanoma (Skin) |
SWOG Cancer Research Network |
2005-06 | PHASE2 |
| NCT00049387 | COMPLETED | Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma |
National Cancer Institute (NCI) |
2002-09 | PHASE1 |
| NCT00365222 | TERMINATED | Glioblastoma; Gliosarcoma |
H. Lee Moffitt Cancer Center and Research Institute |
2006-07 | PHASE2 |
| NCT00362570 | COMPLETED | Oligoastrocytoma, Mixed; Anaplastic Oligodendroglioma |
Ohio State University Comprehensive Cancer Center |
2005-05 | PHASE2 |
| NCT00098436 | COMPLETED | Leukemia |
Vion Pharmaceuticals |
2004-09 | PHASE1 |
| NCT00099125 | COMPLETED | Brain and Central Nervous System Tumors |
Radiation Therapy Oncology Group |
2004-11 | PHASE2 |
| NCT00072163 | COMPLETED | Recurrent Melanoma; Stage IV Melanoma; Tumors Metastatic to Brain |
National Cancer Institute (NCI) |
2003-10 | PHASE2 |
| NCT00147160 | COMPLETED | Glioma |
Gustave Roussy, Cancer Campus, Grand Paris |
2003-10 | PHASE2 |
| NCT00109798 | WITHDRAWN | Central Nervous System Tumors; Lymphoma |
The Methodist Hospital Research Institute |
2005-03 | |
| NCT00076856 | COMPLETED | Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis; Brain Neoplasms |
Merck Sharp & Dohme LLC |
2004-03-31 | PHASE2 |
| NCT00086879 | COMPLETED | Brain and Central Nervous System Tumors |
European Organisation for Research and Treatment of Cancer - EORTC |
2004-05 | PHASE2 |
| NCT00039000 | COMPLETED | Malignant Melanoma |
Agenus Inc. |
2002-03 | PHASE3 |
| NCT00416819 | COMPLETED | Brain and Central Nervous System Tumors; Lymphoma |
University of California, San Francisco |
2003-09 | |
| NCT00137774 | COMPLETED | Neuroendocrine Tumors |
Dana-Farber Cancer Institute |
2004-11 | PHASE2 |
| NCT00027742 | COMPLETED | Intraocular Melanoma; Melanoma (Skin) |
Memorial Sloan Kettering Cancer Center |
2001-05 | PHASE2 |
| NCT00033280 | COMPLETED | Brain and Central Nervous System Tumors |
Radiation Therapy Oncology Group |
2002-07 | PHASE2 |
| NCT00068666 | TERMINATED | Melanoma (Skin); Metastatic Cancer |
Alliance for Clinical Trials in Oncology |
2004-01 | PHASE2 |
| NCT00717210 | COMPLETED | Anaplastic Astrocytoma; Oligodendroglioma; Oligoastrocytoma |
Neuro-Oncology Working Group of the German Cancer Society |
1999-06 | PHASE3 |
| NCT00006024 | COMPLETED | Brain Tumor; Central Nervous System Tumor |
Children's Oncology Group |
2000-11 | PHASE1 |
| NCT00049361 | COMPLETED | Brain and Central Nervous System Tumors; Unspecified Adult Solid Tumor, Protocol Specific |
Wake Forest University Health Sciences |
2004-01-01 | PHASE2 |
| NCT00005815 | COMPLETED | Intraocular Melanoma; Melanoma (Skin) |
Memorial Sloan Kettering Cancer Center |
1999-12 | PHASE1; PHASE2 |
| NCT00072345 | COMPLETED | Intraocular Melanoma; Melanoma (Skin) |
Memorial Sloan Kettering Cancer Center |
2003-07 | PHASE2 |
| NCT00022711 | COMPLETED | Lung Cancer |
Fox Chase Cancer Center |
2002-01 | PHASE2 |
| NCT00020839 | TERMINATED | Melanoma (Skin); Metastatic Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
2001-04 | PHASE3 |
| NCT00004068 | COMPLETED | Brain and Central Nervous System Tumors |
St. Jude Children's Research Hospital |
1999-03 | PHASE2 |
| NCT00006358 | COMPLETED | Brain and Central Nervous System Tumors |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2000-06-13 | PHASE2 |
| NCT00014261 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
Dartmouth-Hitchcock Medical Center |
2000-10 | PHASE1 |
| NCT00021307 | WITHDRAWN | Brain and Central Nervous System Tumors |
Fox Chase Cancer Center |
PHASE1; PHASE2 | |
| NCT00012116 | COMPLETED | Metastatic Cancer |
Jonsson Comprehensive Cancer Center |
2000-10 | PHASE2 |
| NCT00003062 | COMPLETED | Lung Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
1997-07 | PHASE2 |
| NCT00003176 | COMPLETED | Brain and Central Nervous System Tumors |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
1998-03-25 | PHASE2 |
| NCT00006043 | COMPLETED | Ovarian Cancer; Testicular Germ Cell Tumor |
Memorial Sloan Kettering Cancer Center |
2000-02 | PHASE2 |
| NCT00004113 | COMPLETED | Brain and Central Nervous System Tumors |
Memorial Sloan Kettering Cancer Center |
1999-06 | PHASE2 |
| NCT00003731 | COMPLETED | Brain and Central Nervous System Tumors |
European Organisation for Research and Treatment of Cancer - EORTC |
1998-12 | PHASE2 |
| NCT00455286 | UNKNOWN | Primary Central Nervous System Lymphoma |
National Health Research Institutes, Taiwan |
2006-11 | PHASE2 |
| NCT00994071 | COMPLETED | Medulloblastoma; Pontine Glioma; Ependymoma; Astrocytoma; PNET |
National Cancer Institute (NCI) |
2009-09-22 | PHASE1 |
| NCT00004204 | UNKNOWN | Brain and Central Nervous System Tumors |
Herbert Irving Comprehensive Cancer Center |
2000-02 | PHASE2 |
| NCT00514397 | UNKNOWN | Brain and Central Nervous System Tumors |
Children's Cancer and Leukaemia Group |
2008-01 | PHASE2 |
| NCT00283543 | UNKNOWN | Newly Diagnosed Supratentorial Malignant Glioma |
Kentuckiana Cancer Institute |
2002-09 | PHASE2 |
| NCT00033709 | UNKNOWN | Sarcoma |
Herbert Irving Comprehensive Cancer Center |
2002-03 | PHASE2 |
| NCT00897377 | TERMINATED | Astrocytomas; Oligodendrogliomas; Oligoastrocytoma |
Sun Yat-sen University |
2007-12 | PHASE3 |
| NCT00383851 | UNKNOWN | Melanoma |
Attenuon |
2006-09 | PHASE2 |
| NCT00014105 | UNKNOWN | Brain and Central Nervous System Tumors |
Atlantic Health System |
2000-12 | PHASE1; PHASE2 |
| NCT00268684 | UNKNOWN | Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis |
Tel-Aviv Sourasky Medical Center |
2005-05 | PHASE3 |
| NCT00276679 | COMPLETED | Neuroblastoma |
Children's Cancer and Leukaemia Group |
2003-04 | PHASE2 |
| NCT00003464 | COMPLETED | Brain and Central Nervous System Tumors |
Duke University |
1997-09 | PHASE2 |
| NCT00003718 | UNKNOWN | Endometrial Cancer; Ovarian Cancer; Sarcoma |
Herbert Irving Comprehensive Cancer Center |
1998-09 | PHASE2 |
| NCT00005955 | COMPLETED | Brain and Central Nervous System Tumors; Neuroblastoma |
Duke University |
2000-08 | PHASE2 |
| NCT00014092 | COMPLETED | Melanoma (Skin) |
Saint Francis Hospital |
1999-12 | PHASE2 |
| NCT00016055 | UNKNOWN | Melanoma (Skin) |
St. Luke's Medical Center |
2000-11 | PHASE1 |
| NCT00080054 | COMPLETED | Glioma; Glioblastoma; Astrocytoma; Oligodendroglioma; Brain Neoplasm |
Pharmacyclics LLC. |
PHASE1 | |
| NCT00003747 | UNKNOWN | Melanoma (Skin) |
Mount Vernon Cancer Centre at Mount Vernon Hospital |
1998-10 | PHASE1 |
| NCT00003273 | WITHDRAWN | Brain and Central Nervous System Tumors; Neuroblastoma; Retinoblastoma; Sarcoma |
NYU Langone Health |
1997-11 | PHASE2 |
| NCT00194766 | COMPLETED | Breast Cancer; Soft Tissue Sarcoma |
University of Washington |
2000-07 | PHASE2 |
(data from https://clinicaltrials.gov, updated on 2026-05-15)
Check the
TMZ(Temozolomide)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
- TMZ(Temozolomide) Mechanism of Action: MGMT Inhibition in Glioblastoma Cells Research
- TMZ(Temozolomide) Solubility in DMSO
- TMZ(Temozolomide) Storage
- TMZ(Temozolomide) Stability
- TMZ(Temozolomide) Molecular Weight
- TMZ(Temozolomide) SMILES
- TMZ(Temozolomide) CAS Number
- TMZ(Temozolomide) Chemical Structure (2D and 3D)
- TMZ(Temozolomide) Sigma (t2577)? Try a better option.
- TMZ(Temozolomide) Cayman (14163)? Try a better option.
- TMZ(Temozolomide) APExBIO (B1399)? Try a better option.
- TMZ(Temozolomide) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.