BMN-673 (Talazoparib): Selectivity & Specificity
BMN-673 (Talazoparib) is a potent inhibitor of PARP1 (0.56 nM), PARP2 (0.15 nM), PARP3 (63 nM), PARP4 (254 nM), PARP1/2 (0.6 nM), PARP (4 nM), TNSK1, TNSK2. BMN-673 (Talazoparib) exhibits the greatest inhibitory potency toward PARP2 (IC50 = 0.15 nM).