BMN-673 (Talazoparib) is a highly potent PARP1/2 inhibitor. It affects DNA damage response and cGAS-STING signaling pathways by inhibiting PARP catalytic activity and strongly trapping PARP on DNA, thereby inhibiting tumor cell proliferation and promoting apoptosis.
BMN-673 (Talazoparib) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for BMN-673 (Talazoparib) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.