FK506 is a potent calcineurin inhibitor. It affects NFAT signaling pathways, by binding to FKBP12, inhibiting T-cell activation.
FK506 (Tacrolimus) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for FK506 (Tacrolimus) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.