Clinical Trials

Numerous clinical trials evaluate FK506 (Tacrolimus) across Phase 1 through Phase 4, targeting conditions such as kidney, liver, and heart transplantation, organ graft rejection, acute graft-versus-host disease, BK nephropathy, and post-transplant complications. Encompassing completed, actively recruiting, and pending statuses, these studies are sponsored by major academic medical centers and pharmaceutical organizations, including Novartis, Chiesi Pharmaceuticals, Rigshospitalet, and Columbia University. Specific research includes Phase 4 evaluations of modified formulations in liver transplant recipients and Phase 2 studies examining graft-versus-host disease prophylaxis.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT07524530 NOT_YET_RECRUITING
Core Binding Factor Alpha Subunits; Hematologic Neoplasms; Leukemia; Lymphoma
National Cancer Institute (NCI)
2026-09-09 PHASE2
NCT05646992 RECRUITING
Uterine Factor Infertility
Johns Hopkins University
2023-03-01 PHASE2; PHASE3
NCT04877288 RECRUITING
Renal Allograft Recipients
Bristol-Myers Squibb
2021-07-21 PHASE3
NCT06291103 NOT_YET_RECRUITING
Kidney Transplant Rejection
University Hospital, Rouen
2026-07-01 PHASE2; PHASE3
NCT05027945 RECRUITING
Immunodeficiency; Hematopoietic Stem Cell Transplantation
National Cancer Institute (NCI)
2023-02-23 PHASE2
NCT04302870 RECRUITING
Motor Neuron Disease, Amyotrophic Lateral Sclerosis
University of Edinburgh
2020-02-27 PHASE2; PHASE3
NCT06128070 RECRUITING
Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Myelodysplastic Syndrome
City of Hope Medical Center
2024-07-16 PHASE2
NCT07228624 RECRUITING
Myelodysplastic/Myeloproliferative Neoplasm; Primary Myelofibrosis; Secondary Myelofibrosis
Fred Hutchinson Cancer Center
2026-02-04 PHASE2
NCT07493538 RECRUITING
AML; MDS; Acute Leukemia; Acute Myeloid Leukemia; Myelodysplastic Syndromes
Masonic Cancer Center, University of Minnesota
2026-04-10 PHASE2
NCT06126380 ENROLLING_BY_INVITATION
Kidney Transplant Rejection
Eledon Pharmaceuticals
2023-10-25 PHASE2
NCT07412470 RECRUITING
Kidney Transplant Rejection
Sanofi
2026-03-13 PHASE2; PHASE3
NCT07582172 RECRUITING
Acute Myeloid Leukemia With Complex Karyotype; Myelodysplastic Chronic Myelomonocytic Leukemia; Myelodysplastic Syndrome; Recurrent Acute Myeloid Leukemia; Recurrent Myelodysplastic Chronic Myelomonocytic Leukemia; Recurrent Myelodysplastic Syndrome; Recurrent Secondary Acute Myeloid Leukemia; Refractory Acute Myeloid Leukemia; Refractory Myelodysplastic Chronic Myelomonocytic Leukemia; Refractory Myelodysplastic Syndrome; Refractory Secondary Acute Myeloid Leukemia
City of Hope Medical Center
2027-04-05 PHASE2
NCT07359859 RECRUITING
Hematologic Malignancies
Memorial Sloan Kettering Cancer Center
2026-01-20 PHASE2
NCT03779854 ACTIVE_NOT_RECRUITING
Acute Biphenotypic Leukemia; Acute Leukemia; Acute Leukemia of Ambiguous Lineage; Acute Lymphoblastic Leukemia; Acute Undifferentiated Leukemia; Allogeneic Hematopoietic Stem Cell Transplantation Recipient; Blastic Plasmacytoid Dendritic Cell Neoplasm; Blasts Under 25 Percent of Bone Marrow Nucleated Cells; Blasts Under 5 Percent of Bone Marrow Nucleated Cells; Mixed Phenotype Acute Leukemia; Myelodysplastic Syndrome With Excess Blasts-1; Myelodysplastic Syndrome/Acute Myeloid Leukemia; Burkitt Leukemia; Chronic Monocytic Leukemia; Lymphoblastic Lymphoma; Mast Cell Leukemia; Myeloproliferative Neoplasm
Fred Hutchinson Cancer Center
2019-08-29 PHASE2
NCT07204275 RECRUITING
Primary Membranous Nephropathy
Vertex Pharmaceuticals Incorporated
2025-09-30 PHASE2; PHASE3
NCT06815003 RECRUITING
Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Chronic Myelomonocytic Leukemia; Graft Versus Host Disease; Myelodysplastic Syndrome; Myeloproliferative Neoplasm
City of Hope Medical Center
2025-04-18 PHASE2
NCT07290777 RECRUITING
Transplantation, Kidney
Veloxis Pharmaceuticals
2026-08-18 PHASE2
NCT07781722 NOT_YET_RECRUITING
Post-ERCP Pancreatitis
Amsterdam UMC, location VUmc
2026-09-07 PHASE4
NCT06280950 RECRUITING
Liver Transplant
National Institute of Allergy and Infectious Diseases (NIAID)
2024-09-12 PHASE2
NCT06055608 RECRUITING
Kidney Transplant
National Institute of Allergy and Infectious Diseases (NIAID)
2024-05-22 PHASE2
NCT06235892 RECRUITING
Organ Grafts
Nantes University Hospital
2024-12-10 PHASE3
NCT07612657 NOT_YET_RECRUITING
Pulmonary Arterial Hypertension; Pulmonary Arterial Hypertension (PAH); Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH); Pulmonary Arterial Hypertension PAH; Pulmonary Arterial Hypertension WHO Group I
VIVUS LLC
2026-05-29 PHASE3
NCT06287944 RECRUITING
Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Myelodysplastic Syndrome
City of Hope Medical Center
2025-07-01 PHASE1
NCT05088356 ACTIVE_NOT_RECRUITING
Allogeneic Hematopoietic Cell Transplantation (HCT); Advanced Hematologic Malignancies; Acute Leukemia; Chronic Myelogenous Leukemia; Myelodysplastic Syndromes; Myeloproliferative Disorders
Stanford University
2021-09-07 PHASE1
NCT07508787 RECRUITING
Renal Transplant Failure and Rejection
Nefro Avillion Clinical Development, LLC
2026-06-29 PHASE2
NCT07302776 RECRUITING
GVHD; Hematopoietic Cell Transplantation (HCT); Acute Myeloid Leukemia (AML); Myelodysplastic Syndromes; Myelofibrosis (MF); Chronic Myeloid Leukemia (CML); Chronic Myelomonocytic Leukemia (CMML)
Stanford University
2026-07-21 PHASE1
NCT03670966 RECRUITING
Acute Lymphoblastic Leukemia in Remission; Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Acute Myeloid Leukemia in Remission; Chronic Myelomonocytic Leukemia; Myelodysplastic Syndrome With Excess Blasts; Recurrent Acute Lymphoblastic Leukemia; Recurrent Acute Myeloid Leukemia; Refractory Acute Lymphoblastic Leukemia; Refractory Acute Myeloid Leukemia; Recurrent Mixed Phenotype Acute Leukemia; Refractory Mixed Phenotype Acute Leukemia; Hematopoietic and Lymphoid Cell Neoplasm
Fred Hutchinson Cancer Center
2019-07-10 PHASE1; PHASE2
NCT07570433 NOT_YET_RECRUITING
CMV Infection
Oriol Manuel
2026-04 PHASE4
NCT04232085 RECRUITING
Primary Immune Deficiency Disorder; Immune Deficiency Disease; Bone Marrow Failure; Short Telomere Length; Fanconi Anemia; Non Fanconi DNA-DSB Repair Disorder; Hoyeraal-Hreidarsson Syndrome; Dyskeratosis Congenita; Telomere Biology Disorder; Short Telomere Syndrome
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2020-02-12 PHASE2
NCT04542733 ACTIVE_NOT_RECRUITING
Kidney Transplant Infection; BK Virus Infection
King Chulalongkorn Memorial Hospital
2023-06-15
NCT03178149 RECRUITING
Age-Related Macular Degeneration
Astellas Institute for Regenerative Medicine
2018-07-13 PHASE1
NCT01861106 RECRUITING
GATA2; Immunodeficiency; MDS
National Cancer Institute (NCI)
2013-07-24 PHASE2
NCT06591884 RECRUITING
Oral Erosive Lichen Planus
Hospital de Clinicas de Porto Alegre
2024-09-03 PHASE1; PHASE2
NCT05707377 ACTIVE_NOT_RECRUITING
Primary Membranous Nephropathy
BeOne Medicines
2023-04-17 PHASE2; PHASE3
NCT06241118 ACTIVE_NOT_RECRUITING
Dermatitis Atopic
Sanofi
2024-02-29 PHASE3
NCT04022239 RECRUITING
Hematopoietic and Lymphoid System Neoplasm
M.D. Anderson Cancer Center
2020-03-13 PHASE1; PHASE2
NCT06828796 RECRUITING
Hematologic Disease and Disorders; Hematopoietic Cell Transplant
Northside Hospital, Inc.
2025-07-03 PHASE2
NCT04469842 RECRUITING
Lung Transplant; Complications
Vanderbilt University Medical Center
2023-12-01 EARLY_PHASE1
NCT06120140 ACTIVE_NOT_RECRUITING
Carcinoma, Non-Small-Cell Lung
Janssen Research & Development, LLC
2024-02-16 PHASE2
NCT04370301 RECRUITING
Primary Myelofibrosis; Secondary Myelofibrosis
Fred Hutchinson Cancer Center
2021-02-09 PHASE2
NCT04859946 ACTIVE_NOT_RECRUITING
Hematologic and Lymphocytic Disorder
M.D. Anderson Cancer Center
2022-01-11 PHASE2
NCT07138742 NOT_YET_RECRUITING
Vernal Keratoconjunctivitis
Sohag University
2025-09
NCT05736419 RECRUITING
Sickle Cell Disease; Thalassemia, Beta; Thalassemia
Memorial Sloan Kettering Cancer Center
2023-02-09 PHASE2
NCT05621759 ACTIVE_NOT_RECRUITING
Graft Vs Host Disease
NYU Langone Health
2022-09-07 PHASE2
NCT01804634 RECRUITING
Refractory and/or Relapsed Metastatic Solid Tumors
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2013-03-27 PHASE2
NCT07162896 NOT_YET_RECRUITING
Atopic Dermatitis; Atopic Dermatitis (AD)
Shalamar Institute of Health Sciences
2026-06 PHASE3
NCT06084780 NOT_YET_RECRUITING
Secondary Malignant Neoplasm of Retroperitoneum; Secondary Malignant Neoplasm of Peritoneum; Pseudomyxoma Peritonei
Case Comprehensive Cancer Center
2026-08 PHASE2
NCT03769298 RECRUITING
Kidney Pancreas Transplantation
University of Wisconsin, Madison
2019-02-27 PHASE2; PHASE3
NCT06315309 RECRUITING
GVHD,Acute; Acute Leukemia; Myelodysplastic Syndromes; Myeloproliferative Disorders
University of Alabama at Birmingham
2025-04-15 PHASE2
NCT06701825 RECRUITING
Kidney Disease, Chronic; Transplant Recipient (Kidney); Immunosuppression
Instituto de Investigación Hospital Universitario La Paz
2025-06-02 PHASE4
NCT03467386 SUSPENDED
Acute Myeloid Leukemia
City of Hope Medical Center
2018-03-19 PHASE1
NCT04904588 ACTIVE_NOT_RECRUITING
Acute Lymphoblastic Leukemia; Acute Myelogenous Leukemia; Mixed Phenotype Acute Leukemia; Acute Leukemia; Myelodysplastic Syndromes; Chronic Myelogenous Leukemia; Chronic Lymphocytic Leukemia; Lymphoma
Center for International Blood and Marrow Transplant Research
2021-09-30 PHASE2
NCT06203470 NOT_YET_RECRUITING
Psoriasis Vulgaris
Assiut University
2024-06 PHASE4
NCT04384692 ACTIVE_NOT_RECRUITING
Primary Myelofibrosis; Secondary Myelofibrosis
Fred Hutchinson Cancer Center
2020-12-18 PHASE2
NCT06900777 RECRUITING
Vitiligo; Child; Progressive Disease
Xijing Hospital
2025-04-01
NCT03121014 ACTIVE_NOT_RECRUITING
Acute Myeloid Leukemia; Myelodysplastic Syndromes
University of Illinois at Chicago
2017-04-24 PHASE2
NCT06405100 NOT_YET_RECRUITING
Minimal Change Disease
Air Force Military Medical University, China
2024-05 PHASE3
NCT07367932 NOT_YET_RECRUITING
Dermatitis, Atopic; Eczema
Cairo University
2026-02 PHASE4
NCT06306274 ENROLLING_BY_INVITATION
Lymphedema
Odense University Hospital
2024-09-09 PHASE2; PHASE3
NCT03292861 ENROLLING_BY_INVITATION
Heart Transplantation
Cedars-Sinai Medical Center
2018-09-13 PHASE2
NCT07532330 ACTIVE_NOT_RECRUITING
Vitiligo
Minia University
2025-08-01
NCT04965597 COMPLETED
Bone Marrow Failure Syndrome; Congenital Amegakaryocytic Thrombocytopenia; Diamond-Blackfan Anemia; Hereditary Sideroblastic Anemia; Paroxysmal Nocturnal Hemoglobinuria; Shwachman-Diamond Syndrome; Hematologic Neoplasm With Germline GATA2 Mutation; Hematologic Neoplasm With Germline SAMD9 Mutation; Hematologic Neoplasm With Germline SAMD9L Mutation
Fred Hutchinson Cancer Center
2022-04-19 PHASE2
NCT05089604 RECRUITING
Liver Transplantation; Immunosuppression; Neurotoxicity; Tremor; Tacrolimus
University of British Columbia
2023-01-09 PHASE4
NCT06348602 UNKNOWN
Ocular Graft-versus-host Disease
Hospital Universitario Dr. Jose E. Gonzalez
2023-08-01 PHASE1; PHASE2
NCT04207177 UNKNOWN
Kidney Transplant; Complications; Immune Suppression
Oslo University Hospital
2019-10-30 PHASE4
NCT04177004 ACTIVE_NOT_RECRUITING
Allogeneic Hematopoietic Stem Cell Transplant Recipient; Hematopoietic and Lymphoid Cell Neoplasm
City of Hope Medical Center
2021-04-30 PHASE1
NCT06867042 NOT_YET_RECRUITING
Ulcerative Colitis (UC); Ulcerative Colitis, Active Moderate
Jina Pharmaceuticals Inc.
2025-04 PHASE2
NCT05148715 ACTIVE_NOT_RECRUITING
Organ Transplant Failure or Rejection; Brain Death; Ischemic Reperfusion Injury
Université de Sherbrooke
2022-07-11 PHASE2
NCT05156710 ACTIVE_NOT_RECRUITING
Transplant Rejection
Sanofi
2022-06-09 PHASE2
NCT05907746 ACTIVE_NOT_RECRUITING
GATA2; Immunodeficiency
National Cancer Institute (NCI)
2023-11-29 PHASE2
NCT06638879 COMPLETED
Chronic Graft Versus Host Disease Oral
Children's Hospital Medical Center, Cincinnati
2024-09-17 PHASE1
NCT05490511 COMPLETED
CBD; Transplant Complication; Kidney Disease, Chronic
Indiana University
2022-10-31 PHASE1
NCT05916781 UNKNOWN
Systemic Lupus Erythematosus; Lupus Nephritis
Chinese SLE Treatment And Research Group
2023-07-01 PHASE4
NCT04665310 ACTIVE_NOT_RECRUITING
Kidney Disease, End-Stage; Donor Specific Antibodies; Acute Rejection of Renal Transplant
The Methodist Hospital Research Institute
2018-09-01 PHASE4
NCT06183892 RECRUITING
Liver Transplant
RenJi Hospital
2024-03-04
NCT06880042 ENROLLING_BY_INVITATION
Vitiligo - Macular Depigmentation; Tacrolimus
Dr ayesha wahid
2025-05-01 EARLY_PHASE1
NCT05115630 COMPLETED
Myeloid Malignancies; Acute Myeloid Leukemia; Myelodysplastic Syndrome; Chronic Myeloid Leukemia
M.D. Anderson Cancer Center
2022-04-08 PHASE2
NCT04380311 COMPLETED
Heart Transplant Failure and Rejection
University of Utah
2020-05-01
NCT03663933 ACTIVE_NOT_RECRUITING
Lymphoproliferative Disorders; Autoimmune Lymphoproliferative; Primary T-cell Immunodeficiency Disorders; Immune System Diseases; Common Variable Immunodeficiency
National Cancer Institute (NCI)
2018-09-04 PHASE2
NCT07030660 COMPLETED
Kidney Transplantation
KU Leuven
2021-05-11
NCT03480360 COMPLETED
Acute Myeloid Leukemia; Chronic Lymphocytic Leukemia; Chronic Myeloid Leukemia; Myelodysplasia; Myeloproliferative Disorder; Myelofibrosis; Lymphoma; Lymphoma, Non-Hodgkin; Plasma Cell Disorder
Dartmouth-Hitchcock Medical Center
2018-03-28 PHASE3
NCT05256537 ACTIVE_NOT_RECRUITING
Hematologic Neoplasms
Ronald Paquette
2022-04-26 PHASE2
NCT05666336 UNKNOWN
Systemic Lupus Erythematosus
Fen Li
2022-12-31 PHASE4
NCT03689075 TERMINATED
Kidney Transplant Failure; Allosensitization; Immunosuppression
Imperial College Healthcare NHS Trust
2018-11-01 PHASE4
NCT01203722 COMPLETED
Hematologic Malignancies
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2010-09 PHASE1; PHASE2
NCT05005221 COMPLETED
Kidney Transplant
University of Michigan
2022-11-08
NCT04942730 COMPLETED
Leukemia, Acute Lymphoblastic; Myeloid Leukemia, Acute; Biphenotypic Acute Leukemia; Lymphoblastic Lymphoma; Myelodysplastic Syndromes; Myeloproliferative Neoplasm
St. Petersburg State Pavlov Medical University
2021-01-21 PHASE2
NCT05702931 Not yet recruiting
Hyperglycemia|Renal Transplant Complication Primary Non-Function|Diabetes
Rigshospitalet Denmark|Aarhus University Hospital|Odense University Hospital
2024-04-01 Phase 4
NCT05152628 COMPLETED
Liver Transplantation; Kidney Transplantation
Astellas Pharma China, Inc.
2022-01-11 PHASE4
NCT06268769 Recruiting
Immunosuppression
Edward Geissler|Chiesi Pharmaceuticals GmbH|University of Regensburg
2024-03-09 Phase 4
NCT06326775 Active not recruiting
Heart Transplant Patients
Nanjing First Hospital Nanjing Medical University|Wuhan Union Hospital China|Changhai Hospital|Shanghai Zhongshan Hospital
2024-03-12 --
NCT04773392 TERMINATED
Kidney Transplantation; Kidney Transplant Rejection
University of Southern California
2021-11-23 PHASE4
NCT02566304 COMPLETED
Acute Myeloid Leukemia; Acute Myeloid Leukemia in Remission; Aplastic Anemia; Chronic Myelomonocytic Leukemia; Hodgkin Lymphoma; Indolent Non-Hodgkin Lymphoma; Malignant Neoplasm; Myelodysplastic Syndrome; Myeloproliferative Neoplasm; Plasma Cell Myeloma; Refractory Anemia; Refractory Anemia With Excess Blasts; Refractory Anemia With Ring Sideroblasts; Refractory Cytopenia With Multilineage Dysplasia; Refractory Cytopenia With Multilineage Dysplasia and Ring Sideroblasts
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
2015-11-13 PHASE2
NCT06235892 Not yet recruiting
Organ Grafts
Nantes University Hospital
2024-02-10 Phase 3
NCT04646356 COMPLETED
Hereditary Hemorrhagic Telangiectasia; Epistaxis Nosebleed
Unity Health Toronto
2020-10-20 PHASE2
NCT03410654 COMPLETED
Kidney Transplant; Complications
Yale University
2018-10-24 EARLY_PHASE1
NCT07049172 COMPLETED
Nephrotic Syndrome in Children
Wuhan Children's Hospital
2021-01-01
NCT05618730 UNKNOWN
Dry Eye; Keratoconjunctivitis Sicca; Ocular Inflammation
Eximore Ltd.
2022-09-29 PHASE1
NCT02382575 UNKNOWN
Nephrotic Syndrome
Nilratan Sircar Medical College
2015-03-15 PHASE4
NCT04311632 COMPLETED
Kidney Transplantation
ITB-Med LLC
2021-05-26 PHASE2
NCT05532111 UNKNOWN
Efficacy and Safety
RenJi Hospital
2022-09-01
NCT05293509 WITHDRAWN
Stem Cell Transplantation
M.D. Anderson Cancer Center
2022-03-02 PHASE2
NCT01810588 COMPLETED
Hematologic Malignancies
Weill Medical College of Cornell University
2012-10-16 PHASE2
NCT05396898 COMPLETED
Posttransplant Diabetes Mellitus
University Hospital Tuebingen
2020-12-16 PHASE4
NCT02711826 COMPLETED
Kidney Transplant; Adult Living Donor Kidney Transplant Recipients; Renal Transplant; Living Kidney Donor
National Institute of Allergy and Infectious Diseases (NIAID)
2016-09-20 PHASE1; PHASE2
NCT03461445 COMPLETED
Kidney Transplant; Complications; Toxicity; Drug Toxicity; Neurotoxicity
University of California, Davis
2018-04-01 PHASE4
NCT03500848 UNKNOWN
Liver Transplantation
Southern Medical University, China
2018-05-01 PHASE2; PHASE3
NCT04048161 COMPLETED
Nephrotic Syndrome in Children
The Children's Hospital of Zhejiang University School of Medicine
2019-11-12 PHASE4
NCT04489134 COMPLETED
Pharmacokinetics
Rennes University Hospital
2022-02-15 PHASE2
NCT02766465 COMPLETED
Sickle Cell Disease
Medical College of Wisconsin
2017-03-16 PHASE2
NCT05885269 COMPLETED
Alopecia Areata
Combined Military Hospital Abbottabad
2022-11-01 PHASE1
NCT03781414 TERMINATED
Liver Transplant Rejection
Novartis Pharmaceuticals
2019-10-07 PHASE2
NCT03386539 COMPLETED
Pediatric Heart Transplantation; Immunosuppression; Chronic Kidney Diseases; Cardiac Allograft Vasculopathy; Heart Transplant Failure and Rejection; Post-transplant Lymphoproliferative Disorder; Heart Transplant Infection
Boston Children's Hospital
2018-01-29 PHASE3
NCT04154735 WITHDRAWN
Crohn's Disease
Northwestern University
2019-11 PHASE2
NCT04669210 COMPLETED
Graft-versus-host-disease; Stem Cell Transplant Complications; Acute Myeloid Leukemia; Acute Lymphoid Leukemia
St. Petersburg State Pavlov Medical University
2020-11-03 PHASE2
NCT03995901 TERMINATED
Transplanted Organ Rejection
Talaris Therapeutics Inc.
2019-10-25 PHASE3
NCT02960646 COMPLETED
Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Aplastic Anemia; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Chronic Myelomonocytic Leukemia; Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Lymphoblastic Lymphoma; Myelodysplastic Syndrome; Myeloproliferative Neoplasm; Plasma Cell Myeloma; Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma; Recurrent Hodgkin Lymphoma; Recurrent Non-Hodgkin Lymphoma; Recurrent Plasma Cell Myeloma; Therapy-Related Myelodysplastic Syndrome
M.D. Anderson Cancer Center
2017-01-18 PHASE1
NCT05221411 UNKNOWN
Autoimmune Hepatitis
Leiden University Medical Center
2022-01-19 PHASE4
NCT03531281 WITHDRAWN
Hematopoietic and Lymphoid Cell Neoplasm; Hematopoietic Cell Transplantation Recipient
City of Hope Medical Center
2018-12-30 PHASE1
NCT04503616 COMPLETED
Graft-versus-host Disease
NYU Langone Health
2020-09-16 PHASE1; PHASE2
NCT04420195 COMPLETED
Lung Transplant
NYU Langone Health
2020-10-23 PHASE2
NCT02582775 COMPLETED
Epidermolysis Bullosa
Masonic Cancer Center, University of Minnesota
2016-03 PHASE2
NCT02837978 COMPLETED
Arthritis, Rheumatoid
Qiang Shu
2015-01 PHASE4
NCT04903054 WITHDRAWN
Kidney Transplantation; Renal Transplant Recipients
National Institute of Allergy and Infectious Diseases (NIAID)
2022-01-10 PHASE2
NCT02122081 COMPLETED
Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); de Novo Myelodysplastic Syndromes; Previously Treated Myelodysplastic Syndromes; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Secondary Myelodysplastic Syndromes; Untreated Adult Acute Lymphoblastic Leukemia; Untreated Adult Acute Myeloid Leukemia
Sumithira Vasu
2015-07-27 PHASE1
NCT04002115 TERMINATED
Acute Myeloid Leukemia
Milton S. Hershey Medical Center
2020-06-03 PHASE2
NCT02342145 COMPLETED
Beta-Thalassemia Major; Graft-versus-host Disease (GVHD)
Zhongming Zhang
2015-04 PHASE4
NCT01572662 COMPLETED
Leukemia; Acute Myeloid Leukemia; Acute Lymphocytic Leukemia; Chronic Myeloid Leukemia; Chronic Lymphocytic Leukemia; Myeloproliferative Diseases; Non-Hodgkins Lymphoma; Hodgkins Lymphoma; Multiple Myeloma; Myelodysplastic Syndrome
M.D. Anderson Cancer Center
2012-04-11 PHASE2
NCT04403321 COMPLETED
Aplastic Anemia; Drug Effect
Peking Union Medical College Hospital
2020-07-01 PHASE2
NCT03794492 COMPLETED
Kidney Transplant
Chong Kun Dang Pharmaceutical
2018-03-31 PHASE4
NCT03864926 COMPLETED
Delayed Graft Function
University of Wisconsin, Madison
2019-03-18 PHASE4
NCT05353010 UNKNOWN
Healthy
HK inno.N Corporation
2022-05-01 PHASE1
NCT03789006 UNKNOWN
Kidney Transplant Rejection
University of Khartoum
2018-03-21 PHASE4
NCT01904136 COMPLETED
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Acute Myeloid Leukemia With Gene Mutations; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; de Novo Myelodysplastic Syndrome; Myelodysplastic Syndrome; Recurrent Acute Myeloid Leukemia; Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Therapy-Related Acute Myeloid Leukemia
M.D. Anderson Cancer Center
2014-04-22 PHASE1; PHASE2
NCT03088709 TERMINATED
Acute Myeloid Leukemia; Acute Lymphocytic Leukemia; Myelodysplastic Syndrome; Non-hodgkin Lymphoma; Chronic Lymphocytic Leukemia
Loyola University
2017-01-18 PHASE2
NCT02248597 COMPLETED
Graft Versus Host Disease; Hematopoietic/Lymphoid Cancer
Wake Forest University Health Sciences
2015-02-25 PHASE2
NCT04541290 COMPLETED
Breast Cancer Lymphedema
Odense University Hospital
2020-09-22 PHASE1; PHASE2
NCT04810143 COMPLETED
Validate Volumetric Absorptive Microsampling (VAMS) Assay
Children's Hospital Medical Center, Cincinnati
2019-10-07
NCT03171831 UNKNOWN
Thalassemia Major
First Affiliated Hospital of Guangxi Medical University
2017-04-01 PHASE4
NCT02867800 COMPLETED
Sickle Cell Disease; Graft Versus Host Disease
Monica Bhatia
2016-07 PHASE1
NCT03614221 COMPLETED
Atopic Dermatitis
Chang Gung Memorial Hospital
2019-06-03 PHASE2
NCT02909335 WITHDRAWN
Liver Transplantation
Rennes University Hospital
2016-11 PHASE3
NCT05139667 COMPLETED
Oral Lichen Planus
Ain Shams University
2019-05-20 PHASE4
NCT02918292 COMPLETED
Severe Aplastic Anemia
Medical College of Wisconsin
2017-07-03 PHASE2
NCT04590183 UNKNOWN
Posner Schlossman Syndrome
Peking University
2020-10-01
NCT01665677 COMPLETED
Graft vs Host Disease
Mehdi Hamadani
2014-01-20 PHASE2
NCT02833805 COMPLETED
Severe Aplastic Anemia; Aplastic Anemia; Bone Marrow Failure; Immunosuppression
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2016-09 PHASE2
NCT00423514 COMPLETED
Graft Versus Host Disease; Leukemia; Myelodysplastic Syndromes
Memorial Sloan Kettering Cancer Center
2006-11-20 PHASE1; PHASE2
NCT02866682 COMPLETED
Renal Transplant Rejection
University of California, Los Angeles
2018-03-01 PHASE4
NCT04725682 COMPLETED
Healthy Volunteers
Food and Drug Administration (FDA)
2021-01-05 PHASE1
NCT04205240 TERMINATED
Recurrent Plasma Cell Myeloma
Srinivas Devarakonda
2020-12-22 PHASE2
NCT02556931 COMPLETED
Myelodysplastic Syndrome; Chronic Myelomonocytic Leukemia; Small Lymphocytic Lymphoma; Chronic Lymphocytic Leukemia; Prolymphocytic Leukemia; Chronic Myeloid Leukemia; Chronic Myeloproliferative Disorders; Multiple Myeloma; Plasma Cell Neoplasm; Plasma Cell Dyscrasia; Myelofibrosis; Polycythemia Vera; Essential Thrombocythemia; Plasma Cell Leukemia
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2015-12 PHASE2
NCT04114097 COMPLETED
Atopic Dermatitis; Atopic Eczema
Jacob Thyssen
2019-08-22 PHASE4
NCT02736227 COMPLETED
Liver Transplantation
Northwestern University
2016-03
NCT03289650 COMPLETED
End Stage Renal Disease; Rejection of Renal Transplant
Lorenzo Gallon
2017-09-05 PHASE3
NCT04069065 UNKNOWN
Liver Transplant
Chong Kun Dang Pharmaceutical
2019-07-31 PHASE4
NCT03315052 WITHDRAWN
Acute Cellular Graft Rejection; Liver Transplant Rejection
Montefiore Medical Center
2019-01 PHASE4
NCT03277430 UNKNOWN
Mayer Rokitansky Kuster Hauser Syndrome; Mullerian Aplasia; Uterus; Absence, Congenital; Infertility, Female; Uterus Absence, Acquired; Absolute Uterine Factor Infertility
Institute for Clinical and Experimental Medicine
2015-10-09 PHASE3
NCT02921789 COMPLETED
Kidney Transplantation; Primary Focal Segmental Glomerulosclerosis (FSGS)
Astellas Pharma Global Development, Inc.
2017-05-22 PHASE2
NCT04114188 COMPLETED
Renal Transplant Rejection
Prof. Dr. Petra Reinke
2016-12-15 PHASE2
NCT02345850 COMPLETED
Acute Leukemia; Myelodysplasia
National Heart, Lung, and Blood Institute (NHLBI)
2015-08 PHASE3
NCT01095172 UNKNOWN
Function of Renal Transplant
Guy's and St Thomas' NHS Foundation Trust
2010-11 PHASE4
NCT02540395 COMPLETED
Disorder Related to Renal Transplantation; Effects of Immunosuppressant Therapy
Prof. Dr. Petra Reinke
2015-03
NCT04127721 WITHDRAWN
Allogeneic Stem Cell Transplant Recipient; Hematologic and Lymphocytic Disorder; Hematopoietic and Lymphoid Cell Neoplasm
M.D. Anderson Cancer Center
2020-09-22 PHASE2
NCT03465410 COMPLETED
KIDNEY TRANSPLANTATION
NURIA LLOBERAS BLANCH
2017-03-21 PHASE4
NCT03918265 UNKNOWN
Autoimmune Hemolytic Anemia; Pure Red Cell Aplasia; Evans Syndrome
Peking Union Medical College Hospital
2019-05-04 PHASE4
NCT01935128 COMPLETED
Renal Transplant
University of Toledo Health Science Campus
2013-07-03 PHASE4
NCT04258423 TERMINATED
Kidney Failure
Indiana University
2019-12-19 PHASE3
NCT03674411 ACTIVE_NOT_RECRUITING
Acute Myeloid Leukemia; Acute Lymphocytic Leukemia; Biphenotypic/Undifferentiated Leukemia; Chronic Myelogenous Leukemia; Myelodysplasia; Relapsed Large Cell Lymphoma; Mantle Cell Lymphoma; Hodgkin Lymphoma; Burkitt Lymphoma; Relapsed T-Cell Lymphoma; Lymphoplasmacytic Lymphoma
Masonic Cancer Center, University of Minnesota
2019-01-02 PHASE2
NCT02663622 COMPLETED
Graft Versus Host Disease; Hematopoietic Stem Cell Transplantation; Leukemia
Oncoimmune, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
2016-09-19 PHASE2
NCT03527238 COMPLETED
Liver Transplant; Kidney Transplant
University of Florida
2018-09-21 PHASE2
NCT04341038 UNKNOWN
COVID-19; Lung Injury
Hospital Universitari de Bellvitge
2020-04-01 PHASE3
NCT03978494 WITHDRAWN
Kidney Transplant
Sandoz
2019-09-02 PHASE1
NCT03270462 COMPLETED
Renal Transplant Patients
University of Colorado, Denver
2017-12-01 PHASE4
NCT02917096 COMPLETED
Primary Myelofibrosis; Secondary Myelofibrosis
City of Hope Medical Center
2016-11-13 PHASE1
NCT03437577 COMPLETED
Kidney Transplant Failure and Rejection
University of Minnesota
2018-05-08 PHASE1; PHASE2
NCT04023760 COMPLETED
Pharmacokinetics; Kidney Transplant; Lung Transplant
University of Saskatchewan
2019-06-26 PHASE4
NCT04147390 UNKNOWN
Keratopathy
Shahid Beheshti University of Medical Sciences
2019-11 PHASE2; PHASE3
NCT03066466 WITHDRAWN
Acute Myeloid Leukemia; Acute Lymphocytic Leukemia; Myelodysplastic Syndrome
Loyola University
2019-12-10 PHASE3
NCT01685411 TERMINATED
Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Myelodysplastic Syndrome
Masonic Cancer Center, University of Minnesota
2013-01
NCT03062813 UNKNOWN
Hepatitis B Virus Associated Nephrotic Syndrome
Guangdong Provincial People's Hospital
2017-02-01 PHASE4
NCT01885689 ACTIVE_NOT_RECRUITING
Adult Acute Lymphoblastic Leukemia in Remission; Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Adult Acute Myeloid Leukemia in Remission; Myelodysplastic Syndrome; Secondary Myelodysplastic Syndrome; Chronic Myelomonocytic Leukemia; Therapy-Related Myelodysplastic Syndrome
City of Hope Medical Center
2014-02-10 PHASE2
NCT02752529 UNKNOWN
Cirrhosis, Liver
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
2016-03
NCT05032248 COMPLETED
Oral Ulcer; Behcet Syndrome
Assiut University
2019-04-01
NCT01820572 COMPLETED
Kidney Transplantation
Bristol-Myers Squibb
2013-03-27 PHASE3
NCT04041219 COMPLETED
Immunosuppression; Stem Cell Transplant; Bone Marrow Transplant
Mayo Clinic
2019-06-17 PHASE4
NCT03076151 COMPLETED
Transplantation; Kidney; Pharmacokinetic
University Hospital, Limoges
2018-02-12 PHASE4
NCT01955187 COMPLETED
MEMBRANOUS NEPHROPATHY
Hospital Universitario 12 de Octubre
2014-01 PHASE3
NCT02188719 TERMINATED
Liver Transplantation
National Institute of Allergy and Infectious Diseases (NIAID)
2014-12-17 PHASE1
NCT00880815 COMPLETED
CD20 Positive; Chronic Lymphocytic Leukemia; Follicular Lymphoma; Mantle Cell Lymphoma; Marginal Zone Lymphoma; Recurrent Diffuse Large B-Cell Lymphoma; T-Cell Non-Hodgkin Lymphoma
M.D. Anderson Cancer Center
2009-02-17 PHASE1
NCT02627573 TERMINATED
Leukemia, Chronic Myeloid; Myelodysplastic Syndromes; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative
St. Petersburg State Pavlov Medical University
2015-07 PHASE2
NCT00857389 COMPLETED
Stem Cell Transplantation; Leukemia; Lymphoma
M.D. Anderson Cancer Center
2009-03-02 PHASE2
NCT02435901 COMPLETED
Sickle Cell Disease; Beta Thalassemia-Major
Northwell Health
2008-12 PHASE1; PHASE2
NCT01265537 COMPLETED
Acute Graft Rejection; Diabetes
University of British Columbia
2011-06-24
NCT01570348 TERMINATED
Crohn Disease
Fred Hutchinson Cancer Center
2012-07-17 PHASE2
NCT03865888 COMPLETED
Dry Eye; Sjogren Syndrome
Pavly Moawd
2018-10-30 PHASE3
NCT02954159 TERMINATED
Ulcerative Colitis
Medical College of Wisconsin
2017-05-18 PHASE3
NCT02077556 COMPLETED
Drug Interaction Potentiation
National Taiwan University Hospital
2014-04 PHASE4
NCT03358082 UNKNOWN
Vitiligo; Tacrolimus
Sohag University
2017-10-01 PHASE1; PHASE2
NCT02145403 COMPLETED
Hematologic Malignancies; Relapse; Graft-Versus-Host Disease
University of Michigan Rogel Cancer Center
2014-10 PHASE1; PHASE2
NCT03365141 UNKNOWN
Vitiligo; Treatment; Intralesional Injection; Corticosteroid
The Catholic University of Korea
2017-11-14
NCT03465969 COMPLETED
Kidney Transplantation; Liver Transplantation
Astellas Pharma Europe Ltd.
2018-03-20 PHASE4
NCT02953873 COMPLETED
Immunosuppression
Medical University of South Carolina
2017-05-05 PHASE4
NCT02652468 COMPLETED
Lymphoma
University of Wisconsin, Madison
2016-03-10
NCT02961608 COMPLETED
Kidney Transplant; Complications
Hospital Universitari de Bellvitge
2016-05 PHASE4
NCT02882113 UNKNOWN
Liver Dysfunction
Seoul National University Hospital
2016-07 PHASE4
NCT02120157 COMPLETED
Myeloablative Conditioning; HLA-mismatched Bone Marrow Transplantation; Graft Survival; Transplantation, Bone Marrow
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2015-07-02 PHASE2
NCT04761731 COMPLETED
Liver Transplantation
Linical Korea
2015-07 PHASE4
NCT02217410 COMPLETED
Kidney Transplantation
Novartis Pharmaceuticals
2015-02-05 PHASE1; PHASE2
NCT01878786 TERMINATED
Delayed Graft Function
Matthew Cooper
2013-06 PHASE2; PHASE3
NCT02208037 COMPLETED
Acute Leukemia; Chronic Myelogenous Leukemia; Myelodysplasia; Chronic Lymphocytic Leukemia; Small Lymphocytic Lymphoma; Lymphoma, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Hodgkin's Lymphoma
National Heart, Lung, and Blood Institute (NHLBI)
2014-08 PHASE2
NCT03347357 COMPLETED
Nephrotic Syndrome
Shandong University
2012-01-01 PHASE4
NCT02653196 TERMINATED
Neuroepithelial Tumor; Solid Tumor; Allogeneic Hematopoietic Stem Cell Transplantation
Montefiore Medical Center
2015-09 EARLY_PHASE1
NCT03423225 COMPLETED
Liver Transplantation
Kim, Seoung-Hoon
2016-03-22 PHASE4
NCT03083782 COMPLETED
Venous Thromboembolism; Pharmacokinetics; Healthy
Thomas Jefferson University
2017-04-18 PHASE1
NCT02199041 TERMINATED
Hematological Malignancies
St. Jude Children's Research Hospital
2014-07-11 PHASE2
NCT01875237 TERMINATED
Leukemia; Myeloma; Myeloproliferative Diseases
M.D. Anderson Cancer Center
2013-12-27 PHASE1; PHASE2
NCT01580865 COMPLETED
Lupus Nephritis
Ramathibodi Hospital
2012-05
NCT02432833 COMPLETED
End Stage Renal Disease
Chiesi Farmaceutici S.p.A.
2015-05 PHASE4
NCT01790568 COMPLETED
Graft vs Host Disease; Hematologic Neoplasms; Non-Neoplastic Hematologic and Lymphocytic Disorder
University of Michigan Rogel Cancer Center
2014-12 PHASE2
NCT02083991 COMPLETED
Diabetes Mellitus
Vastra Gotaland Region
2013-01 PHASE4
NCT02178683 UNKNOWN
Graft Versus Host Disease
Colorado Blood Cancer Institute
2010-11 PHASE3
NCT02456025 UNKNOWN
Vernal Keratoconjunctivitis
The Eye Center and The Eye Foundation for Research in Ophthalmology
2013-04 PHASE4
NCT01649609 COMPLETED
BK Viremia; BK Nephropathy
Columbia University
2012-03
NCT02373202 COMPLETED
Rheumatoid Arthritis
Sanofi
2015-02 PHASE3
NCT01159080 COMPLETED
Kidney Transplantation
Asan Medical Center
2010-04-01 PHASE4
NCT00589316 TERMINATED
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; CD45-Positive Neoplastic Cells Present; Chronic Myelomonocytic Leukemia; Previously Treated Myelodysplastic Syndrome; Refractory Anemia With Excess Blasts; Refractory Anemia With Ring Sideroblasts; Refractory Cytopenia With Multilineage Dysplasia; Refractory Cytopenia With Multilineage Dysplasia and Ring Sideroblasts
Fred Hutchinson Cancer Center
2007-10-05 PHASE1
NCT00498316 COMPLETED
Myelodysplastic Syndrome; Leukemia
M.D. Anderson Cancer Center
2007-07-03 PHASE1
NCT02601703 COMPLETED
Atopic Dermatitis
Glenmark Pharmaceuticals Ltd. India
2015-08 PHASE3
NCT02528877 WITHDRAWN
Acute Myeloid Leukemia in Remission; Primary Myelofibrosis; Primary Myelofibrosis, Prefibrotic Stage; Secondary Acute Myeloid Leukemia; Secondary Myelofibrosis
City of Hope Medical Center
2015-11 PHASE1
NCT02438982 COMPLETED
Nephrotic Syndrome
Nilratan Sircar Medical College
2015-05-08 PHASE3
NCT01790594 TERMINATED
Simultaneous Kidney and Pancreas Transplantation
National Institute of Allergy and Infectious Diseases (NIAID)
2013-02 PHASE2
NCT01318915 TERMINATED
Renal Transplant Recipients
National Institute of Allergy and Infectious Diseases (NIAID)
2011-07-25 EARLY_PHASE1
NCT02794610 UNKNOWN
Ocular Penetration of Topical Tacrolimus
The Eye Center and The Eye Foundation for Research in Ophthalmology
2016-05
NCT01860183 COMPLETED
Kidney Transplantation; Kidney Failure
Clinical Hospital Merkur
2013-05 PHASE4
NCT01598987 COMPLETED
Renal Function; Liver Transplant
Novartis Pharmaceuticals
2012-10 PHASE3
NCT00533442 COMPLETED
Type 1 Diabetes
University of Miami
2000-09 PHASE2
NCT01856257 TERMINATED
Primary Renal Allograft Candidate; Kidney Transplantation
National Institute of Allergy and Infectious Diseases (NIAID)
2013-07 PHASE2
NCT01451489 TERMINATED
FSGS
Nanjing University School of Medicine
2011-10-13
NCT01895049 COMPLETED
Kidney Transplantation; Cytomegalovirus
Helio Tedesco Silva Junior
2013-08 PHASE4
NCT01655563 COMPLETED
Heart Transplantation; Liver Transplantation; Kidney Transplantation
The Hospital for Sick Children
2011-09 PHASE2
NCT01911546 COMPLETED
Highly-sensitized Kidney Transplant Recipients
Joseph Kahwaji, MD, MPH
2013-06 PHASE2
NCT01889758 COMPLETED
Kidney Transplant Recipients; Liver Transplant Recipients
University of Cincinnati
2013-06 PHASE4
NCT01680952 COMPLETED
Kidney Transplant Patients
Yonsei University
2012-09 PHASE4
NCT02644395 COMPLETED
Hypertension; Kidney Transplantation
Erasmus Medical Center
2013-01-18 PHASE3
NCT01586845 WITHDRAWN
Renal Transplantation
Aurinia Pharmaceuticals Inc.
2013-03 PHASE3
NCT00448357 COMPLETED
Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes
UNC Lineberger Comprehensive Cancer Center
2005-10 PHASE1; PHASE2
NCT01294020 COMPLETED
Intestine Transplantation; Kidney Transplantation; Lung Transplantation; Liver Transplantation; Heart Transplantation
Astellas Pharma Europe Ltd.
2011-05-25 PHASE2
NCT02130817 WITHDRAWN
End Stage Renal Disease; Antibody Mediated Rejection
University of Wisconsin, Madison
2014-09-24 PHASE4
NCT00881556 TERMINATED
Epidermolysis Bullosa
Columbia University
2009-08-20 EARLY_PHASE1
NCT01649427 COMPLETED
Pharmacokinetics Study in de Novo Kidney Transplantation
Novartis Pharmaceuticals
2012-10-17 PHASE4
NCT02014103 COMPLETED
Complication of Transplant
University of Cincinnati
2015-03 PHASE4
NCT02496494 UNKNOWN
CYCLOSPORINE/TACROLIMUS
Kyungpook National University Hospital
2012-09 PHASE4
NCT02744378 COMPLETED
Oral Lichen Planus
University of Peradeniya
2014-06 PHASE2
NCT00933231 COMPLETED
Kidney Transplantation
Astellas Pharma Inc
2009-08-17 PHASE3
NCT01511003 COMPLETED
Rheumatoid Arthritis
Astellas Pharma Inc
2011-12-05 PHASE4
NCT01436305 TERMINATED
Kidney Transplantation; Renal Transplantation
National Institute of Allergy and Infectious Diseases (NIAID)
2011-09 PHASE2
NCT00993343 COMPLETED
Graft-versus-host Disease; Survival
Karolinska Institutet
2007-09 PHASE3
NCT01544842 TERMINATED
Oral Lichen Planus
University of Oulu
2004-08
NCT02123108 COMPLETED
Liver Transplantation
University of California, Los Angeles
2011-01 PHASE4
NCT01055964 COMPLETED
Pharmacokinetics; Tacrolimus
Seoul National University Hospital
2008-09 PHASE3
NCT01680861 COMPLETED
Transplant; Failure, Kidney
Gaetano Ciancio
2012-11 PHASE3
NCT01334333 COMPLETED
Renal Disease; Renal Transplant
University of British Columbia
2011-11-11 PHASE4
NCT01713400 COMPLETED
Graft vs. Host Disease
H. Lee Moffitt Cancer Center and Research Institute
2013-02-25 PHASE2
NCT01518153 TERMINATED
Leukemia; Lymphoma; Myeloma; Myeloproliferative Diseases
M.D. Anderson Cancer Center
2012-02 PHASE2
NCT01244659 WITHDRAWN
Renal Transplant
EMS
2014-05 PHASE3
NCT01608412 UNKNOWN
Kidney Transplant Recipients
Hospital de Clinicas de Porto Alegre
2012-02 PHASE4
NCT01780844 COMPLETED
Kidney Transplantation
Astellas Pharma Global Development, Inc.
2013-03-05 PHASE2
NCT00931255 TERMINATED
Kidney Transplant; Delayed Graft Function
University of Maryland, Baltimore
2009-04 PHASE4
NCT01339468 COMPLETED
Liver Transplantation
Astellas Pharma Inc
2011-04-27 PHASE4
NCT00371319 COMPLETED
Lupus Nephritis
Tuen Mun Hospital
2005-09 PHASE4
NCT01647945 COMPLETED
Pulmonary Arterial Hypertension
Edda Spiekerkoetter
2012-07 PHASE2
NCT02016625 COMPLETED
Healthy
Boehringer Ingelheim
2013-12 PHASE1
NCT00801632 COMPLETED
Kidney Transplantation; Kidney Failure, Chronic
National Institute of Allergy and Infectious Diseases (NIAID)
2008-12 PHASE2
NCT01789255 COMPLETED
Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Grade III Lymphomatoid Granulomatosis; B-cell Chronic Lymphocytic Leukemia; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Chronic Myelomonocytic Leukemia; Chronic Phase Chronic Myelogenous Leukemia; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Graft Versus Host Disease; Intraocular Lymphoma; Myelodysplastic Syndrome With Isolated Del(5q); Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Post-transplant Lymphoproliferative Disorder; Primary Central Nervous System Hodgkin Lymphoma; Primary Central Nervous System Non-Hodgkin Lymphoma; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Refractory Anemia; Refractory Anemia With Excess Blasts; Refractory Anemia With Ringed Sideroblasts; Refractory Chronic Lymphocytic Leukemia; Refractory Cytopenia With Multilineage Dysplasia; Refractory Hairy Cell Leukemia; Relapsing Chronic Myelogenous Leukemia; Secondary Central Nervous System Hodgkin Lymphoma; Secondary Central Nervous System Non-Hodgkin Lymphoma; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Hodgkin Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Small Lymphocytic Lymphoma; Stage II Adult Hodgkin Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Hodgkin Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Hodgkin Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma; Testicular Lymphoma; Waldenström Macroglobulinemia
National Cancer Institute (NCI)
2013-06 PHASE2
NCT00089011 COMPLETED
Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Nasal Type Extranodal NK/T-cell Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Blastic Phase Chronic Myelogenous Leukemia; Childhood Acute Lymphoblastic Leukemia in Remission; Childhood Acute Myeloid Leukemia in Remission; Childhood Burkitt Lymphoma; Childhood Chronic Myelogenous Leukemia; Childhood Diffuse Large Cell Lymphoma; Childhood Immunoblastic Large Cell Lymphoma; Childhood Myelodysplastic Syndromes; Childhood Nasal Type Extranodal NK/T-cell Lymphoma; Chronic Phase Chronic Myelogenous Leukemia; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; de Novo Myelodysplastic Syndromes; Essential Thrombocythemia; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Hepatosplenic T-cell Lymphoma; Intraocular Lymphoma; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Noncutaneous Extranodal Lymphoma; Peripheral T-cell Lymphoma; Polycythemia Vera; Post-transplant Lymphoproliferative Disorder; Previously Treated Myelodysplastic Syndromes; Primary Myelofibrosis; Prolymphocytic Leukemia; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Recurrent Childhood Anaplastic Large Cell Lymphoma; Recurrent Childhood Grade III Lymphomatoid Granulomatosis; Recurrent Childhood Large Cell Lymphoma; Recurrent Childhood Lymphoblastic Lymphoma; Recurrent Childhood Small Noncleaved Cell Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Recurrent/Refractory Childhood Hodgkin Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Hairy Cell Leukemia; Refractory Multiple Myeloma; Relapsing Chronic Myelogenous Leukemia; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Adult T-cell Leukemia/Lymphoma; Stage I Childhood Anaplastic Large Cell Lymphoma; Stage I Childhood Large Cell Lymphoma; Stage I Childhood Lymphoblastic Lymphoma; Stage I Childhood Small Noncleaved Cell Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage I Cutaneous T-cell Non-Hodgkin Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Multiple Myeloma; Stage I Small Lymphocytic Lymphoma; Stage IA Mycosis Fungoides/Sezary Syndrome; Stage IB Mycosis Fungoides/Sezary Syndrome; Stage II Adult T-cell Leukemia/Lymphoma; Stage II Childhood Anaplastic Large Cell Lymphoma; Stage II Childhood Large Cell Lymphoma; Stage II Childhood Lymphoblastic Lymphoma; Stage II Childhood Small Noncleaved Cell Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage II Cutaneous T-cell Non-Hodgkin Lymphoma; Stage II Multiple Myeloma; Stage IIA Mycosis Fungoides/Sezary Syndrome; Stage IIB Mycosis Fungoides/Sezary Syndrome; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Adult T-cell Leukemia/Lymphoma; Stage III Childhood Anaplastic Large Cell Lymphoma; Stage III Childhood Large Cell Lymphoma; Stage III Childhood Lymphoblastic Lymphoma; Stage III Childhood Small Noncleaved Cell Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Multiple Myeloma; Stage III Small Lymphocytic Lymphoma; Stage IIIA Mycosis Fungoides/Sezary Syndrome; Stage IIIB Mycosis Fungoides/Sezary Syndrome; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Adult T-cell Leukemia/Lymphoma; Stage IV Childhood Anaplastic Large Cell Lymphoma; Stage IV Childhood Large Cell Lymphoma; Stage IV Childhood Lymphoblastic Lymphoma; Stage IV Childhood Small Noncleaved Cell Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma; Stage IVA Mycosis Fungoides/Sezary Syndrome; Stage IVB Mycosis Fungoides/Sezary Syndrome; Testicular Lymphoma; Untreated Adult Acute Lymphoblastic Leukemia; Untreated Adult Acute Myeloid Leukemia; Untreated Childhood Acute Lymphoblastic Leukemia; Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies; Waldenström Macroglobulinemia
Fred Hutchinson Cancer Center
2004-04 PHASE2
NCT01120028 COMPLETED
Kidney Transplantation
University of Oxford
2010-09 PHASE2; PHASE3
NCT00263328 COMPLETED
Kidney Transplantation
Pfizer
2005-12 PHASE2
NCT00720629 TERMINATED
Graft Versus Host Disease
H. Lee Moffitt Cancer Center and Research Institute
2007-12 PHASE2
NCT01702181 COMPLETED
Atopic Dermatitis
Otsuka Pharmaceutical Development & Commercialization, Inc.
2012-08 PHASE1
NCT01698541 COMPLETED
End Stage Renal Disease
University of Oslo School of Pharmacy
2013-02 PHASE4
NCT00623012 TERMINATED
Graft Versus Host Disease
Yale University
2008-02 PHASE1; PHASE2
NCT00789308 COMPLETED
Diabetes Mellitus, Type I
National Institute of Allergy and Infectious Diseases (NIAID)
2008-07-11 PHASE2
NCT01564095 TERMINATED
Terminal Liver Disease; Ischemia Reperfusion Injury; Graft Dysfunction; Graft Failure; Poor Graft Quality
Ludwig-Maximilians - University of Munich
2011-10 PHASE2; PHASE3
NCT01154387 UNKNOWN
End Stage Renal Disease; Renal Transplant
Tolera Therapeutics, Inc
2010-07 PHASE1; PHASE2
NCT00965094 COMPLETED
Chronic Renal Failure
Novartis Pharmaceuticals
2009-12 PHASE4
NCT02108301 UNKNOWN
Chronic Hepatitis C-virus Infection; Renal Transplantation
Prof. Dr. Alice Schmidt
2011-12 PHASE4
NCT00731874 TERMINATED
Immunosuppression
Weill Medical College of Cornell University
2008-08 PHASE4
NCT01841008 TERMINATED
Pigmentation Disorders; Vitiligo
Centre Hospitalier Universitaire de Nice
2011-12 PHASE2; PHASE3
NCT00973804 TERMINATED
Leukemia; Non-Hodgkins Lymphoma; Hodgkins Lymphoma; MDS; Multiple Myeloma
National Cancer Institute (NCI)
2009-08-25 PHASE1
NCT00938860 COMPLETED
Hepatitis C; Liver Transplantation
Novartis Pharmaceuticals
2009-09 PHASE4
NCT01742676 COMPLETED
Renal Transplantation; Kidney Transplantation; Stable Renal Recipients
Astellas Pharma Korea, Inc.
2011-04 PHASE4
NCT00693446 UNKNOWN
Pancreas Transplantation; Kidney Transplantation
Nantes University Hospital
2004-04 PHASE4
NCT01476488 COMPLETED
Kidney Transplantation; Pediatric Patients; Maintenance With Tacrolimus
Seoul National University Hospital
2011-07 PHASE2; PHASE3
NCT00332839 TERMINATED
Renal Transplantation
Novartis Pharmaceuticals
2005-11 PHASE4
NCT01187953 COMPLETED
Renal Failure
Veloxis Pharmaceuticals
2010-09 PHASE3
NCT00513474 COMPLETED
Chronic Myeloproliferative Disorders; Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms
Massachusetts General Hospital
2008-01 PHASE1
NCT01323920 COMPLETED
Leukemia; Lymphoma; Myelodysplastic Syndrome
Dana-Farber Cancer Institute
2011-05 PHASE2
NCT01044745 TERMINATED
Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Nasal Type Extranodal NK/T-cell Lymphoma; Blastic Phase Chronic Myelogenous Leukemia; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; de Novo Myelodysplastic Syndromes; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Graft Versus Host Disease; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Previously Treated Myelodysplastic Syndromes; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Relapsing Chronic Myelogenous Leukemia; Secondary Myelodysplastic Syndromes; Splenic Marginal Zone Lymphoma; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Adult T-cell Leukemia/Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage I Cutaneous T-cell Non-Hodgkin Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Mycosis Fungoides/Sezary Syndrome; Stage I Small Lymphocytic Lymphoma; Stage II Adult T-cell Leukemia/Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage II Cutaneous T-cell Non-Hodgkin Lymphoma; Stage II Mycosis Fungoides/Sezary Syndrome; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Adult T-cell Leukemia/Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Mycosis Fungoides/Sezary Syndrome; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Adult T-cell Leukemia/Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Mycosis Fungoides/Sezary Syndrome; Stage IV Small Lymphocytic Lymphoma; Untreated Adult Acute Lymphoblastic Leukemia; Untreated Adult Acute Myeloid Leukemia; Waldenström Macroglobulinemia
University of Nebraska
2009-12-10 PHASE2
NCT00803010 COMPLETED
Acute Graft Versus Host Disease
H. Lee Moffitt Cancer Center and Research Institute
2008-09 PHASE2
NCT01068067 UNKNOWN
Renal Transplantation
Sun Yat-sen University
2010-03
NCT00669890 TERMINATED
Acute Myeloid Leukemia; Juvenile Myelomonocytic Leukemia; Myelodysplastic Syndrome
New York Medical College
2004-05 PHASE1
NCT00934791 TERMINATED
Polycystic Liver Disease
Mayo Clinic
2009-02
NCT00956059 UNKNOWN
Focal Segmental Glomerulosclerosis
Xi'an Jiaotong University
2009-09
NCT02963103 TERMINATED
Kidney Transplantation
Astellas Pharma Korea, Inc.
2010-05 PHASE4
NCT00076570 COMPLETED
Kidney Transplantation
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
2004-01 PHASE2
NCT00859131 COMPLETED
End Stage Renal Disease
Medical University of South Carolina
2009-03
NCT01742624 COMPLETED
de Novo Kidney Transplantation
Astellas Pharma Korea, Inc.
2012-04 PHASE4
NCT01399242 UNKNOWN
Disorder Related to Renal Transplantation
Hospital Universitário São José
2011-08 PHASE4
NCT01135329 TERMINATED
Lymphoma; Leukemia; Myelodysplastic Syndrome
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2010-08 PHASE2
NCT01312064 TERMINATED
Renal Insufficiency
National Taiwan University Hospital
2011-04 PHASE4
NCT00622869 COMPLETED
Liver Transplantation
Novartis Pharmaceuticals
2008-01 PHASE3
NCT01161459 COMPLETED
Idiopathic Membranous Nephropathy
Zhi-Hong Liu, M.D.
2010-06
NCT00322101 COMPLETED
Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome; Acute Myeloid Leukemia/Transient Myeloproliferative Disorder; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Childhood Acute Myeloid Leukemia in Remission; Childhood Myelodysplastic Syndromes; de Novo Myelodysplastic Syndromes; Myelodysplastic Syndrome With Isolated Del(5q); Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Previously Treated Myelodysplastic Syndromes; Recurrent Adult Acute Myeloid Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Secondary Acute Myeloid Leukemia; Secondary Myelodysplastic Syndromes
Fred Hutchinson Cancer Center
2006-01 PHASE3
NCT00589563 COMPLETED
Chronic Myeloproliferative Disorders; Graft Versus Host Disease; Infection; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms; Precancerous Condition; Secondary Myelofibrosis; Small Intestine Cancer
City of Hope Medical Center
2007-05 PHASE2
NCT00639717 COMPLETED
Graft Versus Host Disease
University of Michigan Rogel Cancer Center
2009-03 PHASE2
NCT01160276 COMPLETED
Renal Replacement Therapies
Assistance Publique - Hôpitaux de Paris
2010-05 PHASE1
NCT01206569 COMPLETED
Lupus Nephritis
Chinese University of Hong Kong
2010-09 PHASE4
NCT00464555 COMPLETED
Type 1 Diabetes Mellitus
National Institute of Allergy and Infectious Diseases (NIAID)
2006-12 PHASE2
NCT01850979 COMPLETED
Sjogren Syndrome; Dry Eye Syndrome
University of Sao Paulo General Hospital
2010-02 PHASE4
NCT01122719 TERMINATED
Stable Coronary Disease; Unstable Coronary Disease; Documented Silent Ischemia
CID - Carbostent & Implantable Devices
2010-10
NCT01309477 COMPLETED
Nephrotic Syndrome
Sun Yat-sen University
2011-01 PHASE3
NCT01328834 COMPLETED
Nephritis, Lupus
Sun Yat-sen University
2011-01 PHASE3
NCT00972101 WITHDRAWN
Stem Cell Transplantation; Leukemia; Lymphoma; Pediatric Disorders
M.D. Anderson Cancer Center
2009-09 PHASE1
NCT00737659 UNKNOWN
Renal Transplant
Rabin Medical Center
2008-08 PHASE4
NCT00585468 COMPLETED
Kidney Transplantation
University of Utah
2007-12 PHASE4
NCT01224028 COMPLETED
IgA Nephropathy
Astellas Pharma Inc
2010-11 PHASE2
NCT00246129 COMPLETED
Kidney Transplantation; Kidney Diseases; Kidney Failure
EMagnusson
2005-10 PHASE4
NCT01224041 COMPLETED
Rheumatoid Arthritis
Astellas Pharma Inc
2009-08 PHASE4
NCT01591070 COMPLETED
Seborrheic Dermatitis
Pusan National University Hospital
2010-11 PHASE4
NCT00876616 COMPLETED
Lupus Nephritis
Zhi-Hong Liu, M.D.
2009-04
NCT00105001 COMPLETED
Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Previously Treated Myelodysplastic Syndrome; Refractory Chronic Lymphocytic Leukemia; Refractory Plasma Cell Myeloma; Waldenstrom Macroglobulinemia; Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With t(9;11)(p22;q23); MLLT3-MLL; Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11; Adult Acute Promyelocytic Leukemia With t(15;17)(q22;q12); PML-RARA; Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1; Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Childhood Acute Lymphoblastic Leukemia in Remission; Childhood Acute Myeloid Leukemia in Remission; Childhood Burkitt Lymphoma; Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Childhood Diffuse Large Cell Lymphoma; Childhood Immunoblastic Lymphoma; Childhood Myelodysplastic Syndrome; Stage II Contiguous Adult Burkitt Lymphoma; Stage II Contiguous Adult Diffuse Large Cell Lymphoma; Stage II Contiguous Adult Diffuse Mixed Cell Lymphoma; Stage II Contiguous Adult Diffuse Small Cleaved Cell Lymphoma; Stage II Adult Contiguous Immunoblastic Lymphoma; Stage II Contiguous Adult Lymphoblastic Lymphoma; Stage II Grade 1 Contiguous Follicular Lymphoma; Stage II Grade 2 Contiguous Follicular Lymphoma; Stage II Grade 3 Contiguous Follicular Lymphoma; Stage II Contiguous Mantle Cell Lymphoma; Stage II Non-Contiguous Adult Burkitt Lymphoma; Stage II Non-Contiguous Adult Diffuse Large Cell Lymphoma; Stage II Non-Contiguous Adult Diffuse Mixed Cell Lymphoma; Stage II Non-Contiguous Adult Diffuse Small Cleaved Cell Lymphoma; Stage II Adult Non-Contiguous Immunoblastic Lymphoma; Stage II Non-Contiguous Adult Lymphoblastic Lymphoma; Stage II Grade 1 Non-Contiguous Follicular Lymphoma; Stage II Grade 2 Non-Contiguous Follicular Lymphoma; Stage II Grade 3 Non-Contiguous Follicular Lymphoma; Stage II Non-Contiguous Mantle Cell Lymphoma; Stage II Small Lymphocytic Lymphoma; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Recurrent Childhood Anaplastic Large Cell Lymphoma; Recurrent Childhood Large Cell Lymphoma; Recurrent Childhood Lymphoblastic Lymphoma; Recurrent Childhood Burkitt Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Recurrent Childhood Hodgkin Lymphoma; Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Secondary Myelodysplastic Syndrome; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Immunoblastic Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Childhood Anaplastic Large Cell Lymphoma; Stage I Childhood Large Cell Lymphoma; Stage I Childhood Lymphoblastic Lymphoma; Stage I Childhood Burkitt Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Small Lymphocytic Lymphoma; Stage II Childhood Anaplastic Large Cell Lymphoma; Stage II Childhood Lymphoblastic Lymphoma; Stage II Childhood Burkitt Lymphoma; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Immunoblastic Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Childhood Anaplastic Large Cell Lymphoma; Stage III Childhood Large Cell Lymphoma; Stage III Childhood Lymphoblastic Lymphoma; Stage III Childhood Burkitt Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Immunoblastic Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Childhood Anaplastic Large Cell Lymphoma; Stage IV Childhood Large Cell Lymphoma; Stage IV Childhood Lymphoblastic Lymphoma; Stage IV Childhood Burkitt Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma
Fred Hutchinson Cancer Center
2004-11 PHASE2
NCT00049504 COMPLETED
Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Nasal Type Extranodal NK/T-cell Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Childhood Acute Lymphoblastic Leukemia in Remission; Childhood Acute Myeloid Leukemia in Remission; Childhood Burkitt Lymphoma; Childhood Chronic Myelogenous Leukemia; Childhood Myelodysplastic Syndromes; Childhood Nasal Type Extranodal NK/T-cell Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; de Novo Myelodysplastic Syndromes; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Hematopoietic/Lymphoid Cancer; Hepatosplenic T-cell Lymphoma; Intraocular Lymphoma; Nodal Marginal Zone B-cell Lymphoma; Peripheral T-cell Lymphoma; Post-transplant Lymphoproliferative Disorder; Previously Treated Myelodysplastic Syndromes; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Childhood Anaplastic Large Cell Lymphoma; Recurrent Childhood Grade III Lymphomatoid Granulomatosis; Recurrent Childhood Large Cell Lymphoma; Recurrent Childhood Lymphoblastic Lymphoma; Recurrent Childhood Small Noncleaved Cell Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Recurrent/Refractory Childhood Hodgkin Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Multiple Myeloma; Relapsing Chronic Myelogenous Leukemia; Secondary Myelodysplastic Syndromes; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Stage II Multiple Myeloma; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Hodgkin Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Adult T-cell Leukemia/Lymphoma; Stage III Childhood Hodgkin Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Multiple Myeloma; Stage III Mycosis Fungoides/Sezary Syndrome; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Hodgkin Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Adult T-cell Leukemia/Lymphoma; Stage IV Childhood Hodgkin Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Mycosis Fungoides/Sezary Syndrome; Stage IV Small Lymphocytic Lymphoma; Testicular Lymphoma; Waldenström Macroglobulinemia
Fred Hutchinson Cancer Center
2002-01 PHASE2
NCT00543569 COMPLETED
Kidney Transplantation
Astellas Pharma Inc
2008-02 PHASE2
NCT00316810 COMPLETED
Pancreas-Kidney Transplantation
Dr. Claudia Bösmüller
2006-04 PHASE3
NCT00448201 COMPLETED
Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes
UNC Lineberger Comprehensive Cancer Center
2011-01-07 PHASE2
NCT00360685 COMPLETED
Mucositis; Graft-versus-host Disease
H. Lee Moffitt Cancer Center and Research Institute
2005-09
NCT00922129 WITHDRAWN
Prostate Cancer
St. Joseph's Healthcare Hamilton
2009-09 PHASE2; PHASE3
NCT00504348 COMPLETED
Interstitial Pneumonitis; Polymyositis; Dermatomyositis
Tokyo Medical and Dental University
2007-07 PHASE2; PHASE3
NCT01324934 TERMINATED
Renal Transplant Rejection
Neovii Biotech
2006-10 PHASE3
NCT00311311 TERMINATED
Atherosclerosis; Kidney Failure
Pfizer
2006-04 PHASE3
NCT00489203 COMPLETED
Hematopoietic/Lymphoid Cancer; Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Atypical Chronic Myeloid Leukemia; Blastic Phase Chronic Myelogenous Leukemia; Childhood Acute Lymphoblastic Leukemia in Remission; Childhood Acute Myeloid Leukemia in Remission; Childhood Chronic Myelogenous Leukemia; Childhood Myelodysplastic Syndromes; Chronic Eosinophilic Leukemia; Chronic Myelomonocytic Leukemia; Chronic Neutrophilic Leukemia; Chronic Phase Chronic Myelogenous Leukemia; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; de Novo Myelodysplastic Syndromes; Essential Thrombocythemia; Extramedullary Plasmacytoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Graft Versus Host Disease; Isolated Plasmacytoma of Bone; Juvenile Myelomonocytic Leukemia; Meningeal Chronic Myelogenous Leukemia; Myelodysplastic/Myeloproliferative Disease, Unclassifiable; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Previously Treated Myelodysplastic Syndromes; Primary Myelofibrosis; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Recurrent/Refractory Childhood Hodgkin Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Hairy Cell Leukemia; Relapsing Chronic Myelogenous Leukemia; Secondary Myelodysplastic Syndromes; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Hodgkin Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Adult T-cell Leukemia/Lymphoma; Stage I Childhood Hodgkin Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage I Cutaneous T-cell Non-Hodgkin Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Multiple Myeloma; Stage I Mycosis Fungoides/Sezary Syndrome; Stage I Small Lymphocytic Lymphoma; Stage II Adult Hodgkin Lymphoma; Stage II Adult T-cell Leukemia/Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage II Cutaneous T-cell Non-Hodgkin Lymphoma; Stage II Multiple Myeloma; Stage II Mycosis Fungoides/Sezary Syndrome; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Hodgkin Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Adult T-cell Leukemia/Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Multiple Myeloma; Stage III Mycosis Fungoides/Sezary Syndrome; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Hodgkin Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Adult T-cell Leukemia/Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Mycosis Fungoides/Sezary Syndrome; Stage IV Small Lymphocytic Lymphoma
Fred Hutchinson Cancer Center
2007-04 PHASE2
NCT01764581 COMPLETED
Liver Disease
University of Bologna
2008-07
NCT03751332 COMPLETED
Immunosuppression; Renal Failure
Medical University of Vienna
2008-03 PHASE4
NCT00555048 TERMINATED
Graft Versus Host Disease; Leukemia; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases
Fred Hutchinson Cancer Center
2007-09 PHASE1; PHASE2
NCT01388517 COMPLETED
Pityriasis Alba
Universidad Autonoma de San Luis Potosí
2008-01 PHASE4
NCT00787761 COMPLETED
Myeloproliferative Disorders; Kidney Cancer; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases
Northside Hospital, Inc.
2007-04 PHASE2
NCT00369226 COMPLETED
Hematologic Malignancies
Dana-Farber Cancer Institute
2006-08 PHASE1; PHASE2
NCT01413685 TERMINATED
Renal Transplant Rejection
Assistance Publique - Hôpitaux de Paris
2009-01 PHASE4
NCT00492661 COMPLETED
Renal Transplantion; Kidney Transplantion
Janssen-Cilag Pty Ltd
2007-07 PHASE4
NCT01183247 COMPLETED
Comparative Study; Immunosuppressive Agents
University Hospital, Basel, Switzerland
2008-07 PHASE4
NCT00771745 COMPLETED
Renal Transplant Rejection; Transplants and Implants
University of Cincinnati
2008-09 PHASE4
NCT01092806 COMPLETED
Post Transplant Diabetes Mellitus
University of Oslo School of Pharmacy
2009-10 PHASE4
NCT00302536 WITHDRAWN
Focal Glomerulosclerosis
Nanjing University School of Medicine
2006-03
NCT01038167 COMPLETED
Hepatitis C
Vertex Pharmaceuticals Incorporated
2010-01 PHASE1
NCT00909571 COMPLETED
Liver Transplantation
Astellas Pharma Inc
2009-04 PHASE3
NCT02660684 COMPLETED
Graft Versus Host Disease
Astellas Pharma Korea, Inc.
2008-02 PHASE4
NCT00833079 COMPLETED
Atopic Dermatitis
Sun Pharmaceutical Industries, Inc.
2008-10 PHASE1
NCT00765661 COMPLETED
Kidney Failure; Renal Failure
Veloxis Pharmaceuticals
2008-09 PHASE2
NCT00733733 UNKNOWN
Renal Transplant Patients; Recipients of a Kidney From a Non-Heart-Beating Donor
Radboud University Medical Center
2008-01 PHASE3
NCT01709136 TERMINATED
Hypertension
University of Pittsburgh
2005-12 PHASE2; PHASE3
NCT00538265 COMPLETED
Liver Transplantation
University Hospital, Toulouse
2005-05 PHASE4
NCT00223041 TERMINATED
Renal Transplantation
University Hospital Schleswig-Holstein
2003-04 PHASE2; PHASE3
NCT00506922 COMPLETED
Leukemia; Lymphoma
M.D. Anderson Cancer Center
2000-09 PHASE1; PHASE2
NCT00240994 COMPLETED
Kidney Failure, Chronic; Kidney Transplantation; Immunosuppression
National Institute of Allergy and Infectious Diseases (NIAID)
2005-01 PHASE2
NCT02118896 COMPLETED
Heart Transplantation; Liver Transplantation; Kidney Transplantation
Astellas Pharma Europe Ltd.
2003-02-24 PHASE3
NCT00790439 WITHDRAWN
Diabetes Mellitus, Type I
National Institute of Allergy and Infectious Diseases (NIAID)
2008-07 PHASE2
NCT01550445 UNKNOWN
Disorder Related to Renal Transplantation
Ajou University School of Medicine
2008-05 PHASE4
NCT00654355 COMPLETED
Atopic Dermatitis
Wake Forest University
2008-04 PHASE4
NCT00720408 COMPLETED
Liver Transplantation; Transplantation Immunology; Host vs Graft Reaction
Astellas Pharma Inc
2007-12 PHASE3
NCT00436722 TERMINATED
Liver Diseases
Hospital Clinic of Barcelona
2006-06 PHASE2
NCT00301951 COMPLETED
Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes
University of California, San Francisco
2004-09 PHASE1
NCT01828879 COMPLETED
Dermatitis, Atopic
Janssen-Cilag Ltd.,Thailand
2007-11 PHASE4
NCT00299221 COMPLETED
Immunosuppression
Newark Beth Israel Medical Center
2004-04 PHASE4
NCT00472082 TERMINATED
Kidney Transplantation; Chronic Kidney Failure
Emory University
2007-05 PHASE1; PHASE2
NCT00481481 COMPLETED
Transplantation
Astellas Pharma Inc
2007-04 PHASE3
NCT00481819 COMPLETED
Kidney Transplantation
Astellas Pharma Inc
2007-07 PHASE3
NCT00113269 COMPLETED
Kidney Transplantation
Astellas Pharma Inc
2005-05 PHASE4
NCT00596947 TERMINATED
Transplants and Implants
University of Pennsylvania
2005-10 PHASE4
NCT00619398 COMPLETED
Liver Transplantation
Astellas Pharma Inc
2008-01 PHASE3
NCT00282282 COMPLETED
Graft Versus Host Disease; GVHD
Dana-Farber Cancer Institute
2006-01 PHASE2
NCT00298506 COMPLETED
Lupus Nephritis
Nanjing University School of Medicine
2005-09
NCT00779792 UNKNOWN
Dermatitis, Contact; Dermatitis, Occupational
Odense University Hospital
2008-09 PHASE4
NCT00282256 COMPLETED
Liver Transplantation
Astellas Pharma Inc
2004-01 PHASE2
NCT00319917 COMPLETED
Rheumatoid Arthritis
Astellas Pharma Inc
2006-04 PHASE4
NCT00170053 COMPLETED
Kidney Diseases
Mayo Clinic
2005-06 PHASE1
NCT00818194 COMPLETED
Healthy
Astellas Pharma Inc
2008-04 PHASE1
NCT00615667 COMPLETED
Kidney Diseases; Nephrotic Syndrome; Tacrolimus
Sun Yat-sen University
2006-06 PHASE3
NCT00452361 TERMINATED
Kidney Transplantation
Wyeth is now a wholly owned subsidiary of Pfizer
2007-04 PHASE4
NCT01269684 WITHDRAWN
Kidney Transplantation
Novartis Pharmaceuticals
2008-08 PHASE4
NCT00118742 COMPLETED
Liver Transplantation
Hoffmann-La Roche
2005-08 PHASE4
NCT00905515 COMPLETED
Kidney Transplantation
East Carolina University
2003-08 PHASE4
NCT00719745 COMPLETED
Liver Transplantation
Astellas Pharma Inc
2006-02 PHASE3
NCT00295607 COMPLETED
Hepatitis C; Liver Transplantation
Astellas Pharma Inc
2005-06 PHASE2
NCT00403416 COMPLETED
Kidney Transplantation
Novartis Pharmaceuticals
2006-10 PHASE1; PHASE2
NCT00643071 COMPLETED
Ulcerative Colitis
Astellas Pharma Inc
2006-09 PHASE3
NCT00038948 COMPLETED
Renal Transplantation
Wyeth is now a wholly owned subsidiary of Pfizer
2002-01 PHASE3
NCT00104975 COMPLETED
Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms
Yale University
2005-02 PHASE1
NCT00525681 COMPLETED
Renal Transplantation
University of Oslo School of Pharmacy
2007-09 PHASE4
NCT00117702 TERMINATED
Graft vs Host Disease
Technische Universität Dresden
2005-10 PHASE2; PHASE3
NCT00492869 COMPLETED
Kidney Transplantation
Novartis Pharmaceuticals
2007-01 PHASE1; PHASE2
NCT00347048 COMPLETED
Ulcerative Colitis
Astellas Pharma Inc
2006-09 PHASE3
NCT00608517 TERMINATED
Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes
Vanderbilt-Ingram Cancer Center
2005-09
NCT00167557 WITHDRAWN
Hepatitis C
The University of Texas Health Science Center, Houston
2005-01 PHASE4
NCT00321113 COMPLETED
KIDNEY TRANSPLANTATION
Astellas Pharma Inc
2004-09 PHASE3
NCT00611351 COMPLETED
Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases; Secondary Myelofibrosis
University of Nebraska
2005-06-07 PHASE2
NCT00121186 TERMINATED
Lymphoma
SWOG Cancer Research Network
2005-07 PHASE2
NCT00374231 COMPLETED
Liver Transplantation
University of Cincinnati
2002-10 PHASE4
NCT00374803 COMPLETED
End Stage Renal Disease (ESRD)
University of Cincinnati
2006-04 PHASE4
NCT00865137 COMPLETED
Kidney Transplantation
Astellas Pharma Inc
2007-09 PHASE3
NCT00384202 COMPLETED
Transplantation
Astellas Pharma Inc
2006-10 PHASE3
NCT00275535 COMPLETED
Kidney Diseases
Mayo Clinic
2001-04 PHASE4
NCT00321074 COMPLETED
LIVER TRANSPLANTATION
Astellas Pharma Inc
2005-05 PHASE3
NCT01080534 COMPLETED
Healthy Volunteers
Panacea Biotec Ltd
2007-09
NCT01080482 COMPLETED
Healthy Volunteers
Panacea Biotec Ltd
2007-09
NCT01080456 COMPLETED
Healthy Volunteers
Panacea Biotec Ltd
2007-09
NCT00087581 COMPLETED
Kidney Transplantation
Hoffmann-La Roche
2004-06 PHASE4
NCT00293917 COMPLETED
Psoriasis
Astellas Pharma Inc
2006-01 PHASE3
NCT00384137 COMPLETED
Transplantation
Astellas Pharma Inc
2006-10 PHASE3
NCT00295594 COMPLETED
Liver Transplantation
Astellas Pharma Inc
2005-03 PHASE3
NCT00014469 COMPLETED
Graft Versus Host Disease; Leukemia; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms
Memorial Sloan Kettering Cancer Center
2000-12 PHASE2
NCT00133172 TERMINATED
Kidney Transplantation
Astellas Pharma Inc
2005-07 PHASE4
NCT00189839 COMPLETED
Kidney Transplantation
Astellas Pharma Inc
2004-08 PHASE3
NCT00053196 COMPLETED
Leukemia; Lymphoma; Multiple Myeloma; Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myeloproliferative Neoplasms
Alliance for Clinical Trials in Oncology
2002-12 PHASE2
NCT00141037 COMPLETED
Kidney Diseases; Kidney Transplantation; Kidney Transplant; Renal Transplantation; Renal Transplant
National Institute of Allergy and Infectious Diseases (NIAID)
2004-03 PHASE1; PHASE2
NCT00148746 COMPLETED
Moderate to Severe Atopic Dermatitis
Technische Universität Dresden
2004-05
NCT00912678 COMPLETED
Kidney Transplantation
University of Luebeck
2002-03 PHASE4
NCT00296361 COMPLETED
Kidney Transplantation
Astellas Pharma Inc
2004-10 PHASE3
NCT00109993 COMPLETED
Breast Cancer; Chronic Myeloproliferative Disorders; Gestational Trophoblastic Tumor; Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases; Neuroblastoma; Ovarian Cancer; Testicular Germ Cell Tumor
Case Comprehensive Cancer Center
2005-01 PHASE2
NCT00027573 COMPLETED
Kidney Cancer
Alliance for Clinical Trials in Oncology
2001-10 PHASE2
NCT00171743 COMPLETED
Liver Transplant
Novartis
2004-04 PHASE4
NCT00089947 COMPLETED
Renal Transplantation; Graft Rejection
Genzyme, a Sanofi Company
2003-06 PHASE2
NCT00239876 COMPLETED
Renal Transplantation
Novartis Pharmaceuticals
2005-05 PHASE3
NCT00170833 COMPLETED
Renal Transplantation
Novartis Pharmaceuticals
2003-11 PHASE3
NCT00656266 TERMINATED
End-stage Liver Disease; Renal Insufficiency; Renal Failure
Baylor College of Medicine
2004-11 PHASE4
NCT00480610 COMPLETED
Dermatitis, Atopic
Astellas Pharma Inc
2004-04 PHASE3
NCT00189735 COMPLETED
Kidney Transplantation; Renal Transplantation; Transplantation, Renal; Transplantation, Kidney; Grafting, Kidney
Astellas Pharma Inc
2003-09 PHASE2
NCT00523952 COMPLETED
Dermatitis, Atopic
Astellas Pharma Inc
2004-01 PHASE3
NCT00189787 COMPLETED
Asthma, Bronchial; Bronchial Asthma
Astellas Pharma Inc
PHASE2
NCT01068054 COMPLETED
Keratoconjunctivitis, Vernal
Siriraj Hospital
2003-06 PHASE2; PHASE3
NCT00644761 COMPLETED
Hepatitis B
Gilead Sciences
2004-02 PHASE2
NCT00056966 COMPLETED
Hematologic Malignancy
Baylor College of Medicine
2002-11 PHASE1; PHASE2
NCT00089037 COMPLETED
Chronic Myeloproliferative Disorders; Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases
Fred Hutchinson Cancer Center
2003-06 PHASE1; PHASE2
NCT00691145 COMPLETED
Dermatitis, Atopic
Astellas Pharma Inc
2002-10 PHASE3
NCT00691262 COMPLETED
Dermatitis, Atopic
Astellas Pharma Inc
2003-10 PHASE3
NCT00285194 COMPLETED
Type 1 Diabetes; Hypoglycemia
University of Minnesota
2000-04 PHASE1; PHASE2
NCT00002809 COMPLETED
Leukemia; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases
Temple University
1996-08 PHASE2
NCT00666302 COMPLETED
Dermatitis, Atopic
Astellas Pharma Inc
2002-10 PHASE4
NCT00034528 TERMINATED
Hemoglobinopathies; Anemia, Sickle Cell; Hemoglobin SC Disease; Thalassemia; Thalassemia Major
National Institute of Allergy and Infectious Diseases (NIAID)
2001-09 PHASE2
NCT00048399 TERMINATED
Graft Failure
Baylor College of Medicine
2000-12 PHASE1; PHASE2
NCT00056979 TERMINATED
Inherited Metabolic Storage Diseases
Baylor College of Medicine
2002-06 PHASE1; PHASE2
NCT00002792 COMPLETED
Chronic Myeloproliferative Disorders; Leukemia; Myelodysplastic/Myeloproliferative Diseases
Fred Hutchinson Cancer Center
1996-06 PHASE2
NCT00006747 COMPLETED
Graft Versus Host Disease; Lymphoma
Alliance for Clinical Trials in Oncology
2000-11 PHASE2
NCT00041288 TERMINATED
Leukemia; Lymphoma
University of Texas Southwestern Medical Center
2001-10 PHASE2
NCT00003572 COMPLETED
Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
1998-08 PHASE2
NCT00006350 COMPLETED
Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes
University of Maryland, Baltimore
2000-01 PHASE2
NCT00134394 COMPLETED
Psoriasis
University of Medicine and Dentistry of New Jersey
2005-02 PHASE2
NCT00286871 COMPLETED
Chronic Hepatitis C; Organ Transplantation; Immunosuppression
Duke University
2006-02 PHASE1
NCT00028171 COMPLETED
Kidney Transplantation
National Center for Research Resources (NCRR)
NCT00195429 COMPLETED
Kidney Failure; Graft vs Host Disease
Wyeth is now a wholly owned subsidiary of Pfizer
2005-08 PHASE4
NCT00178425 COMPLETED
Transplantation, Liver
University of Rochester
2005-01 PHASE4
NCT00007787 COMPLETED
Kidney Transplantation; Chronic Allograft Nephropathy
National Institute of Allergy and Infectious Diseases (NIAID)
2000-04
NCT00510913 COMPLETED
Graft Rejection; Kidney Transplantation
Astellas Pharma Inc
1999-02 PHASE4
NCT00560378 COMPLETED
Dermatitis, Atopic; Eczema, Atopic
Astellas Pharma Inc
1998-06 PHASE3
NCT00141804 UNKNOWN
Kidney Transplantation
University Hospital Muenster
2002-01 PHASE3
NCT00567762 COMPLETED
Keratoconjunctivitis; Conjunctivitis
Astellas Pharma Inc
2004-02 PHASE3
NCT01268995 TERMINATED
New Onset Diabetes Mellitus After Renal Transplantation
Medical University of Vienna
2009-09 PHASE2
NCT00807690 COMPLETED
Vitiligo
Oslo University Hospital
2005-11 PHASE3
NCT00518271 COMPLETED
Kidney Transplantation
Wyeth is now a wholly owned subsidiary of Pfizer
2000-04 PHASE2
NCT00004255 COMPLETED
Graft Versus Host Disease; Leukemia; Myelodysplastic Syndromes
Chimeric Therapies
2000-03 PHASE2; PHASE3
NCT00166842 UNKNOWN
Transplantation; Kidney Transplantation; Immunosuppression
National Taiwan University Hospital
2002-09 PHASE4
NCT00175253 COMPLETED
Type 1 Diabetes
University of Alberta
2005-11 PHASE2
NCT00140543 COMPLETED
Diabetes Mellitus, Type 1; Diabetic Nephropathy
EUROSPK Study Group
2002-02 PHASE3
NCT00261820 COMPLETED
Graft Rejection; Kidney Failure; Kidney Transplantation
Wyeth is now a wholly owned subsidiary of Pfizer
PHASE4
NCT00325325 UNKNOWN
Kidney Diseases
Hospital Universitario Ramon y Cajal
2006-01 PHASE2
NCT00195988 COMPLETED
Liver Transplantation
Children's Memorial Health Institute, Poland
2002-09 PHASE4
NCT00223015 COMPLETED
Renal Transplantation
University Hospital Schleswig-Holstein
2004-05 PHASE4
NCT00236106 COMPLETED
Atopic Dermatitis
Children´s Clinic, Randers
2005-02 PHASE4
NCT00304720 UNKNOWN
Multiple Myeloma; Lymphoma; Acute Myelogenous Leukemia; Acute Lymphocytic Leukemia; Myelodysplastic Syndrome
Colorado Blood Cancer Institute
2004-03 PHASE2
NCT00293891 COMPLETED
Psoriasis
Astellas Pharma Inc
PHASE3
NCT00116103 COMPLETED
Asthma
Astellas Pharma Inc
2005-06 PHASE2
NCT00177099 COMPLETED
Alopecia
Hordinsky, Maria K., MD
2003-07 PHASE1

(data from https://clinicaltrials.gov, updated on 2026-09-04)

Check the FK506 (Tacrolimus) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Tacrolimus binds to the immunophilin FKBP12 to form a complex that inhibits the phosphatase activity of calcineurin, thereby preventing calcium-dependent transcription of lymphokine genes and suppressing T-cell activation. This inhibition of cellular immune responses and inflammatory mediator release directly underlies its clinical utility in preventing organ transplant rejection and treating acute graft-versus-host disease.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

Note: Technical data last updated: Sep 1, 2026.