2D Structure
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2D chemical structural formula diagram.
3D Structure
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This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
FK506 (Tacrolimus)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-prop-2-enyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone | |
|---|---|---|
| CAS Number | 104987-11-3 | |
| Molecular Formula |
C44H69NO12 |
|
| Molecular Weight (MW) | 804.02 | |
| SMILES | CC1CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC(=O)C(C=C(C1)C)CC=C)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC | |
| InChIKey | QJJXYPPXXYFBGM-LFZNUXCKSA-N |
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
120 mg/mL
(149.25 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(124.37 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(124.37 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(124.37 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(124.37 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- FK506 (Tacrolimus) Mechanism of Action: Calcineurin Inhibition in T-Lymphocyte Research
- FK506 (Tacrolimus) Clinical Trials
- FK506 (Tacrolimus): Selectivity & Specificity
- FK506 (Tacrolimus) Working Concentration | Cell Culture | Treatment
- FK506 (Tacrolimus) Solubility in DMSO
- FK506 (Tacrolimus) Stock Solution
- FK506 (Tacrolimus) Storage
- FK506 (Tacrolimus) Stability
- FK506 (Tacrolimus) Combination Database
- FK506 (Tacrolimus) Molecular Weight
- FK506 (Tacrolimus) SMILES
- FK506 (Tacrolimus) CAS Number
- FK506 (Tacrolimus) IC50 for Cell-based and Cell-free Assays
- FK506 (Tacrolimus) MedChemExpress (HY-13756)? Try a better option.
- FK506 (Tacrolimus) Sigma (PHR1809)? Try a better option.
- FK506 (Tacrolimus) Tocris (3631)? Try a better option.
- FK506 (Tacrolimus) Abmole (M1934)? Try a better option.
- FK506 (Tacrolimus) Cayman (10007965)? Try a better option.
- FK506 (Tacrolimus) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.