Sorafenib is an ATP-competitive multikinase inhibitor. It affects MAPK signaling by blocking ATP sites, inhibiting tumor growth.
Sorafenib (BAY 43-9006) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Sorafenib (BAY 43-9006) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.