Sorafenib has an extensive clinical development profile featuring numerous clinical trials spanning Early Phase 1 through Phase 4 evaluations. Sponsored by pharmaceutical developers like Bayer and academic institutions such as Memorial Sloan Kettering Cancer Center, these studies evaluate its therapeutic potential across malignancies including hepatocellular carcinoma, acute myeloid leukemia, pancreatic cancer, prostate cancer, bladder cancer, and adrenocortical carcinoma. Recruitment statuses encompass recruiting, active not recruiting, completed, terminated, and withdrawn stages, including Phase 2 combination studies in advanced pancreatic cancer and Phase 1/2 studies in acute myeloid leukemia.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT07787429 | RECRUITING | Osteosarcoma |
Anna Raciborska |
2026-04-01 | PHASE2 |
| NCT05468359 | RECRUITING | Refractory Solid Tumor; Hepatocellular Carcinoma; Malignant Solid Tumor; Pediatric Cancer; Pediatric Solid Tumor; Fibrolamellar Carcinoma |
St. Jude Children's Research Hospital |
2022-11-07 | PHASE1; PHASE2 |
| NCT02559778 | RECRUITING | Neuroblastoma |
Giselle Sholler |
2015-09 | PHASE2 |
| NCT06972641 | RECRUITING | AML; MDS |
Ruijin Hospital |
2025-06-10 | PHASE2; PHASE3 |
| NCT07560566 | RECRUITING | Hepato Cellular Carcinoma (HCC); Hand Foot Skin Syndrome |
National Taiwan University Hospital |
2025-12-09 | PHASE2 |
| NCT06227221 | NOT_YET_RECRUITING | Type 1 Diabetes |
Second Xiangya Hospital of Central South University |
2026-02 | PHASE2 |
| NCT07463651 | RECRUITING | Acute Myeloid Leukemia (AML); FLT3-ITD Mutation; Allogeneic Hematopoietic Cell Transplantation (HCT); Maintenance Therapy; Gilteritinib; Sorafenib |
The First Affiliated Hospital of Soochow University |
2026-05-01 | PHASE3 |
| NCT02029001 | RECRUITING | Malignant Solid Neoplasms |
Centre Leon Berard |
2014-03 | PHASE2 |
| NCT03132454 | ACTIVE_NOT_RECRUITING | Recurrent Acute Lymphoblastic Leukemia; Recurrent Acute Myeloid Leukemia; Refractory Acute Lymphoblastic Leukemia; Refractory Acute Myeloid Leukemia |
M.D. Anderson Cancer Center |
2017-07-25 | PHASE1 |
| NCT01141309 | ACTIVE_NOT_RECRUITING | Thyroid Cancer |
Memorial Sloan Kettering Cancer Center |
2010-06 | PHASE2 |
| NCT06532084 | RECRUITING | Acute Myeloid Leukemia, in Relapse; Myelodysplastic Syndromes; Chronic Myeloid Leukemia; Myeloproliferative Neoplasm |
St. Petersburg State Pavlov Medical University |
2024-05-22 | PHASE2 |
| NCT01840592 | ACTIVE_NOT_RECRUITING | Hepatocellular Carcinoma |
Memorial Sloan Kettering Cancer Center |
2013-04 | PHASE2 |
| NCT03533582 | ACTIVE_NOT_RECRUITING | Childhood Hepatocellular Carcinoma; Childhood Malignant Liver Neoplasm; Fibrolamellar Carcinoma; Hepatoblastoma; Hepatocellular Malignant Neoplasm, Not Otherwise Specified |
Children's Oncology Group |
2018-05-24 | PHASE3 |
| NCT00494182 | ACTIVE_NOT_RECRUITING | Metastatic Head and Neck Squamous Cell Carcinoma; Metastatic Squamous Cell Carcinoma of the Hypopharynx; Metastatic Squamous Cell Carcinoma of the Larynx; Metastatic Squamous Cell Carcinoma of the Oral Cavity; Metastatic Squamous Cell Carcinoma of the Oropharynx; Recurrent Head and Neck Squamous Cell Carcinoma; Recurrent Hypopharyngeal Squamous Cell Carcinoma; Recurrent Laryngeal Squamous Cell Carcinoma; Recurrent Oral Cavity Squamous Cell Carcinoma; Recurrent Oropharyngeal Squamous Cell Carcinoma |
M.D. Anderson Cancer Center |
2007-04-25 | PHASE2 |
| NCT07264010 | NOT_YET_RECRUITING | Acute Myeloid Leukaemia (AML); Measurable Residual Disease (MRD) |
Nanfang Hospital, Southern Medical University |
2025-12-01 | PHASE2; PHASE3 |
| NCT06309485 | RECRUITING | Advanced Hepatocellular Carcinoma (HCC) |
Zhejiang Haichang Biotech Co., Ltd. |
2024-07-31 | PHASE2 |
| NCT01871766 | ACTIVE_NOT_RECRUITING | Rhabdomyosarcoma |
St. Jude Children's Research Hospital |
2013-12-04 | PHASE2 |
| NCT04344158 | ACTIVE_NOT_RECRUITING | Advanced Hepatocellular Carcinoma (HCC) |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
2020-08-11 | PHASE3 |
| NCT05033522 | SUSPENDED | Hepatocellular Carcinoma |
Mirror Biologics, Inc. |
2023-08-01 | PHASE2; PHASE3 |
| NCT05822752 | ACTIVE_NOT_RECRUITING | Hepatocellular Carcinoma |
AbbVie |
2023-09-21 | PHASE2 |
| NCT04039607 | COMPLETED | Hepatocellular Carcinoma |
Bristol-Myers Squibb |
2019-09-30 | PHASE3 |
| NCT04720716 | COMPLETED | Hepatocellular Carcinoma |
Innovent Biologics (Suzhou) Co. Ltd. |
2021-02-07 | PHASE3 |
| NCT03899428 | RECRUITING | Hepatocellular Carcinoma |
Humanity & Health Medical Group Limited |
2019-05-02 | PHASE2 |
| NCT05594095 | RECRUITING | Breast Neoplasm; Breast Cancer; Hormone Receptor Positive Tumor; HER2-negative Breast Cancer; Advanced Breast Cancer |
Fudan University |
2022-12-30 | PHASE2 |
| NCT06437353 | RECRUITING | Ovarian Cancer |
Anhui Provincial Cancer Hospital |
2024-05-25 | PHASE2 |
| NCT03164057 | ACTIVE_NOT_RECRUITING | Acute Myeloid Leukemia; Myelodysplastic Syndromes |
St. Jude Children's Research Hospital |
2017-06-15 | PHASE2 |
| NCT06474663 | WITHDRAWN | Refractory Acute Leukemia; Relapsed Acute Leukemia |
M.D. Anderson Cancer Center |
2025-07-31 | PHASE1 |
| NCT02716012 | UNKNOWN | Hepatocellular Carcinoma; Liver Cancer |
Mina Alpha Limited |
2016-03-01 | PHASE1 |
| NCT05117957 | COMPLETED | Advanced Hepatocellular Carcinoma |
Bo Hyun Kim |
2022-03-08 | PHASE2 |
| NCT06797427 | COMPLETED | Healthy |
Disruptive Pharma |
2025-02-10 | EARLY_PHASE1 |
| NCT04710641 | COMPLETED | Hepatocellular Carcinoma; Hepatitis B; Hepatitis C |
Mina Alpha Limited |
2022-01-01 | PHASE2 |
| NCT04709380 | TERMINATED | Radiotherapy; Toripalimab; Sorafenib; Advanced Hepatocellular Carcinoma |
Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
2021-03-02 | PHASE3 |
| NCT06482086 | RECRUITING | Locally Advanced Thyroid Gland Carcinoma |
West China Hospital |
2021-06-01 | PHASE2 |
| NCT06527495 | UNKNOWN | HCC; Hepatocellular Carcinoma |
Assiut University |
2023-01-01 | PHASE1; PHASE2 |
| NCT02733809 | UNKNOWN | Hepatocellular Carcinoma |
King Saud University |
2014-01 | PHASE4 |
| NCT06073730 | UNKNOWN | Elderly AML Patients; Unfit, New-diagnosis AML; Acute Myeloid Leukemia; Venetoclax; Decitabine |
The Second Affiliated Hospital of Kunming Medical University |
2023-11-01 | PHASE3 |
| NCT04170556 | COMPLETED | Hepatocellular Carcinoma |
Fundacion Clinic per a la Recerca Biomédica |
2020-03-16 | PHASE1; PHASE2 |
| NCT04723004 | COMPLETED | Advanced Hepatocellular Carcinoma (HCC) |
Shanghai Junshi Bioscience Co., Ltd. |
2020-10-15 | PHASE3 |
| NCT04560894 | UNKNOWN | Hepatocellular Carcinoma |
Sinocelltech Ltd. |
2020-11-11 | PHASE2; PHASE3 |
| NCT04000737 | COMPLETED | Advanced Hepatocellular Carcinoma |
Yiviva Inc. |
2020-01-10 | PHASE2 |
| NCT06030895 | COMPLETED | Hepatocellular Carcinoma |
Damanhour University |
2022-12-12 | |
| NCT02794337 | UNKNOWN | Carcinoma, Hepatocellular |
Tata Memorial Hospital |
2014-12 | PHASE2; PHASE3 |
| NCT03477175 | COMPLETED | Solid Tumors |
Eisai Inc. |
2018-08-16 | PHASE2 |
| NCT04135690 | UNKNOWN | Hepatocellular Carcinoma |
Sun Yat-sen University |
2019-10-20 | PHASE2 |
| NCT04387695 | UNKNOWN | Unresectable Hepatocellular Carcinoma; Portal Vein Thrombosis |
First Affiliated Hospital of Zhejiang University |
2020-04-30 | PHASE3 |
| NCT03211416 | COMPLETED | Advanced Adult Hepatocellular Carcinoma; Child-Pugh Class A; Stage III Hepatocellular Carcinoma; Stage IIIA Hepatocellular Carcinoma; Stage IIIB Hepatocellular Carcinoma; Stage IIIC Hepatocellular Carcinoma; Stage IV Hepatocellular Carcinoma; Stage IVA Hepatocellular Carcinoma; Stage IVB Hepatocellular Carcinoma |
Roswell Park Cancer Institute |
2017-12-07 | PHASE1; PHASE2 |
| NCT01624285 | COMPLETED | Adult Primary Hepatocellular Carcinoma; Localized Resectable Adult Primary Liver Cancer; Localized Unresectable Adult Primary Liver Cancer; Recurrent Adult Primary Liver Cancer |
Jonsson Comprehensive Cancer Center |
2012-07-16 | PHASE2 |
| NCT05391867 | UNKNOWN | Hepatocellular Carcinoma |
Sir Salimullah Medical College Mitford Hospital |
2022-01-01 | |
| NCT04674345 | UNKNOWN | Acute Leukemia; Relapse; Hematopoietic Stem Cell Transplantation |
Nanfang Hospital, Southern Medical University |
2020-12-15 | PHASE2; PHASE3 |
| NCT04229355 | UNKNOWN | Hepatocellular Carcinoma |
Guangxi Medical University |
2021-02-02 | PHASE3 |
| NCT04611165 | COMPLETED | Advanced Hepatocellular Carcinoma |
National Cancer Center, Korea |
2019-11-15 | PHASE2 |
| NCT02143401 | COMPLETED | Cirrhosis; Hepatitis B Infection; Hepatitis C Infection; Metastatic Malignant Solid Neoplasm; Recurrent Hepatocellular Carcinoma; Recurrent Malignant Solid Neoplasm; Refractory Malignant Neoplasm; Stage IV Hepatocellular Carcinoma AJCC v7; Unresectable Solid Neoplasm |
National Cancer Institute (NCI) |
2015-01-30 | PHASE1 |
| NCT04599777 | COMPLETED | Hepatocellular Carcinoma Non-resectable |
Second Affiliated Hospital of Guangzhou Medical University |
2020-10-01 | PHASE2 |
| NCT03412773 | COMPLETED | Hepatocellular Carcinoma (HCC) |
BeiGene |
2017-12-18 | PHASE3 |
| NCT01730937 | COMPLETED | Adult Primary Hepatocellular Carcinoma; Advanced Adult Primary Liver Cancer; Recurrent Adult Primary Liver Cancer |
Radiation Therapy Oncology Group |
2013-04 | PHASE3 |
| NCT01906216 | COMPLETED | Hepatocellular Carcinoma |
Air Force Military Medical University, China |
2013-09 | PHASE3 |
| NCT01724606 | COMPLETED | Breast Cancer; Brain Metastases |
Memorial Sloan Kettering Cancer Center |
2012-11-05 | PHASE1 |
| NCT03764293 | COMPLETED | Locally Advanced or Metastatic and Unresectable HCC |
Jiangsu HengRui Medicine Co., Ltd. |
2019-06-10 | PHASE3 |
| NCT03236649 | TERMINATED | Hepatocellular Carcinoma (HCC) |
Beijing Shenogen Biomedical Co., Ltd |
2017-09-20 | PHASE3 |
| NCT02728050 | COMPLETED | Acute Biphenotypic Leukemia; Acute Myeloid Leukemia; de Novo Myelodysplastic Syndrome; Myelodysplastic Syndrome; Myeloproliferative Neoplasm |
University of Washington |
2016-12-01 | PHASE1; PHASE2 |
| NCT04985136 | TERMINATED | Advanced Hepatocellular Carcinoma (HCC) |
Jiangsu HengRui Medicine Co., Ltd. |
2021-09-26 | PHASE3 |
| NCT03775395 | UNKNOWN | Hepatocellular Carcinoma |
Sun Yat-sen University |
2018-12-12 | PHASE3 |
| NCT02638428 | UNKNOWN | Relapsed Pediatric Solid Tumor; Refractory Pediatric Solid Tumor; Relapsed Pediatric AML; Refractory Pediatric AML |
Samsung Medical Center |
2015-12 | PHASE2 |
| NCT03582618 | TERMINATED | Hepatocellular Carcinoma; Advanced Cancer |
TaiRx, Inc. |
2018-07-12 | PHASE2 |
| NCT03730675 | UNKNOWN | Hepatocellular Carcinoma; Portal Vein Tumor Thrombosis |
Zhongda Hospital |
2018-11-10 | |
| NCT04926532 | UNKNOWN | Hepatocellular Carcinoma |
Shanghai Zhongshan Hospital |
2019-08-01 | PHASE1; PHASE2 |
| NCT05068752 | Recruiting | Pancreas Cancer |
HonorHealth Research Institute|Bayer|Genentech Inc. |
2021-10-28 | Phase 2 |
| NCT00625378 | COMPLETED | Neoplasms |
Bayer |
2007-12-21 | PHASE3 |
| NCT04143191 | UNKNOWN | Hepatocellular Carcinoma |
Sun Yat-sen University |
2019-09-15 | PHASE3 |
| NCT03298451 | ACTIVE_NOT_RECRUITING | Hepatocellular Carcinoma |
AstraZeneca |
2017-10-11 | PHASE3 |
| NCT02504983 | UNKNOWN | Hepatocellular Carcinoma |
Chang Gung Memorial Hospital |
2015-08 | PHASE4 |
| NCT01621906 | COMPLETED | Metastatic Breast Cancer to the Brain |
Memorial Sloan Kettering Cancer Center |
2012-06-13 | |
| NCT01180959 | COMPLETED | Liver Cancer |
M.D. Anderson Cancer Center |
2011-04-14 | PHASE2 |
| NCT04763408 | Active not recruiting | Carcinoma Hepatocellular |
Eisai Inc. |
2021-04-09 | -- |
| NCT03722498 | WITHDRAWN | Hepatocellular Carcinoma |
Sun Yat-sen University |
2018-06-01 | PHASE2 |
| NCT02642913 | COMPLETED | Hepatocellular Carcinoma |
Memorial Sloan Kettering Cancer Center |
2015-12 | PHASE1 |
| NCT01004978 | COMPLETED | Hepatocellular Carcinoma; Unresectable Hepatocellular Carcinoma |
National Cancer Institute (NCI) |
2009-10-28 | PHASE3 |
| NCT03008512 | TERMINATED | Carcinoma, Hepatocellular |
Gachon University Gil Medical Center |
2016-10 | PHASE2 |
| NCT02143726 | ACTIVE_NOT_RECRUITING | Refractory Hurthle Cell Thyroid Cancer |
Alliance for Clinical Trials in Oncology |
2014-10-09 | PHASE2 |
| NCT03606590 | COMPLETED | Hepatocellular Carcinoma |
NovoCure Ltd. |
2019-02-15 | PHASE2 |
| NCT03275376 | TERMINATED | Overall Survival; Tumor Responses |
Taichung Veterans General Hospital |
2017-12-21 | PHASE2 |
| NCT01900002 | COMPLETED | Advanced Adult Hepatocellular Carcinoma; BCLC Stage C Hepatocellular Carcinoma; Recurrent Adult Hepatocellular Carcinoma; Stage III Hepatocellular Carcinoma AJCC v7; Stage IIIA Hepatocellular Carcinoma AJCC v7; Stage IIIB Hepatocellular Carcinoma AJCC v7; Stage IIIC Hepatocellular Carcinoma AJCC v7; Stage IV Hepatocellular Carcinoma AJCC v7; Stage IVA Hepatocellular Carcinoma AJCC v7; Stage IVB Hepatocellular Carcinoma AJCC v7; Unresectable Hepatocellular Carcinoma |
M.D. Anderson Cancer Center |
2013-09-13 | PHASE2 |
| NCT01664182 | COMPLETED | Advanced Renal Cell Carcinoma; Advanced Sarcomatoid Renal Cell Carcinoma; Stage III Renal Cell Cancer AJCC v7; Stage IV Renal Cell Cancer AJCC v7 |
National Cancer Institute (NCI) |
2012-08-01 | PHASE2 |
| NCT03780634 | WITHDRAWN | Hepatocellular Carcinoma |
Sun Yat-sen University |
2019-04-01 | PHASE2 |
| NCT01248247 | COMPLETED | Lung Cancer |
M.D. Anderson Cancer Center |
2011-06-02 | PHASE2 |
| NCT01578109 | COMPLETED | Acute Myeloid Leukemia With FLT3/ITD Mutation |
National Cancer Institute (NCI) |
2012-01-13 | PHASE1 |
| NCT01434602 | COMPLETED | Brain Tumor; Glioblastoma; Anaplastic Glioma |
National Cancer Institute (NCI) |
2012-10-02 | PHASE1; PHASE2 |
| NCT04069949 | UNKNOWN | Unresectable Hepatocellular Cancer; Portal Vein Tumor Thrombus |
Sichuan University |
2019-12-01 | PHASE1; PHASE2 |
| NCT02856126 | COMPLETED | Hepatocellular Carcinoma |
Sun Yat-sen University |
2016-08 | PHASE3 |
| NCT00892424 | COMPLETED | Liver Metastasis; Cancer |
University Health Network, Toronto |
2008-11 | PHASE1; PHASE2 |
| NCT01817751 | COMPLETED | Glioblastoma; Recurrent Adult Brain Neoplasm; Malignant Glioma; WHO Grade III Glioma |
Virginia Commonwealth University |
2013-04-11 | PHASE2 |
| NCT02562755 | COMPLETED | Hepatocellular Carcinoma (HCC) |
SillaJen, Inc. |
2015-10 | PHASE3 |
| NCT02908165 | WITHDRAWN | Hepatocellular Carcinoma |
Yale University |
2016-06 | PHASE2 |
| NCT01666756 | COMPLETED | Adult Primary Hepatocellular Carcinoma; Advanced Adult Primary Liver Cancer; Advanced Adult Hepatocellular Carcinoma; BCLC Stage B Adult Hepatocellular Carcinoma; BCLC Stage C Adult Hepatocellular Carcinoma |
City of Hope Medical Center |
2014-06-11 | PHASE1 |
| NCT02349867 | COMPLETED | Pancreatic Adenocarcinoma; Stage IA Pancreatic Cancer; Stage IB Pancreatic Cancer; Stage IIA Pancreatic Cancer; Stage IIB Pancreatic Cancer; Stage III Pancreatic Cancer; Recurrent Pancreatic Carcinoma |
Virginia Commonwealth University |
2015-01-29 | PHASE1 |
| NCT00543504 | COMPLETED | Advanced Cancer |
M.D. Anderson Cancer Center |
2007-10-10 | PHASE1 |
| NCT03518502 | UNKNOWN | Hepatocellular Carcinoma; Metastasis |
Korea University |
2012-03-01 | PHASE4 |
| NCT02988440 | COMPLETED | Hepatocellular Carcinoma |
Novartis Pharmaceuticals |
2017-04-20 | PHASE1 |
| NCT03140332 | COMPLETED | Hepatocellular Carcinoma; Perfusion Scanner |
Centre Hospitalier Universitaire, Amiens |
2017-02-27 | |
| NCT02747537 | WITHDRAWN | Pediatric Solid Tumors |
Washington University School of Medicine |
2016-06-24 | PHASE2 |
| NCT03406364 | COMPLETED | Solid Tumor |
Metagone Biotech Inc. |
2018-06-06 | PHASE1 |
| NCT03812783 | UNKNOWN | Hepatocellular Carcinoma |
Sun Yat-sen University |
2018-11-05 | PHASE2 |
| NCT02836847 | UNKNOWN | Cholangiocarcinoma of the Extrahepatic Bile Duct; Gallbladder Cancer |
Shanghai Jiao Tong University School of Medicine |
2016-07 | PHASE2 |
| NCT03630120 | TERMINATED | Thyroid Cancer; Thyroid Cancer, Medullary; Differentiated Thyroid Cancer; Papillary Thyroid Cancer; Follicular Thyroid Cancer; Poorly Differentiated Thyroid Gland Carcinoma |
H. Lee Moffitt Cancer Center and Research Institute |
2018-08-06 | PHASE2 |
| NCT00892658 | COMPLETED | Hepatocellular Carcinoma |
University Health Network, Toronto |
2009-01 | PHASE1 |
| NCT05517239 | COMPLETED | Hepatocellular Carcinoma, Unresectable, Advanced |
Yonsei University |
2015-05-01 | PHASE2 |
| NCT03812770 | UNKNOWN | Hepatocellular Carcinoma |
Sun Yat-sen University |
2018-08-04 | PHASE2 |
| NCT02867280 | TERMINATED | Hepatocellular Carcinoma; Recurrence |
Sun Yat-sen University |
2016-06-01 | PHASE3 |
| NCT02072486 | COMPLETED | Advanced Adult Hepatocellular Carcinoma; Localized Non-Resectable Adult Hepatocellular Carcinoma; Stage III Childhood Hepatocellular Carcinoma; Stage IIIA Hepatocellular Carcinoma; Stage IIIB Hepatocellular Carcinoma; Stage IIIC Hepatocellular Carcinoma; Stage IV Childhood Hepatocellular Carcinoma; Stage IVA Hepatocellular Carcinoma; Stage IVB Hepatocellular Carcinoma |
Roswell Park Cancer Institute |
2013-11-18 | |
| NCT02624700 | TERMINATED | Breast Cancer; Metastatic Breast Cancer; Recurrent Breast Cancer |
Virginia Commonwealth University |
2016-01-28 | PHASE2 |
| NCT02066181 | COMPLETED | Desmoid Fibromatosis |
National Cancer Institute (NCI) |
2014-03-21 | PHASE3 |
| NCT02279719 | COMPLETED | Hepatocellular Carcinoma |
Sumitomo Pharma America, Inc. |
2014-12 | PHASE1; PHASE2 |
| NCT01964235 | WITHDRAWN | Advanced Hepatocellular Carcinoma |
Novartis Pharmaceuticals |
2016-12 | PHASE2 |
| NCT02576509 | COMPLETED | Hepatocellular Carcinoma |
Bristol-Myers Squibb |
2015-12-07 | PHASE3 |
| NCT03499626 | UNKNOWN | Advanced/ Metastatic Hepatocellular Carcinoma |
National University Hospital, Singapore |
2017-05-05 | PHASE1; PHASE2 |
| NCT03578874 | COMPLETED | Hepatocellular Carcinoma |
The University of Hong Kong |
2016-06-20 | PHASE2 |
| NCT00634634 | COMPLETED | Metastatic Breast Cancer |
Rutgers, The State University of New Jersey |
2008-08-11 | PHASE1; PHASE2 |
| NCT01628640 | COMPLETED | Advanced Malignant Solid Neoplasm; Hepatocellular Carcinoma |
Mayo Clinic |
2012-08-03 | PHASE1 |
| NCT02530476 | COMPLETED | Leukemia; Acute Myeloid Leukemia |
M.D. Anderson Cancer Center |
2015-12-08 | PHASE1; PHASE2 |
| NCT01371981 | COMPLETED | Acute Myeloid Leukemia; Leukemia Cutis; Myeloid Neoplasm; Myeloid Sarcoma |
National Cancer Institute (NCI) |
2011-07-06 | PHASE3 |
| NCT02748304 | TERMINATED | Hepatocellular Carcinoma |
Fudan University |
2016-04 | |
| NCT03097848 | UNKNOWN | HCC |
Southwest Hospital, China |
2017-05-04 | |
| NCT05121571 | COMPLETED | Hepatocellular Carcinoma |
Sun Yat-sen University |
2016-04-21 | |
| NCT02187081 | UNKNOWN | HCC |
Southwest Hospital, China |
2017-03-15 | |
| NCT02330783 | UNKNOWN | Metastatic Renal Cell Carcinoma |
Peking University Cancer Hospital & Institute |
2014-12 | PHASE2 |
| NCT02196857 | COMPLETED | Leukemia |
M.D. Anderson Cancer Center |
2015-02-06 | PHASE2 |
| NCT03516071 | COMPLETED | Hepatocellular Carcinoma (HCC) |
Zai Lab (Shanghai) Co., Ltd. |
2017-05-17 | PHASE2 |
| NCT02627963 | COMPLETED | Carcinoma, Renal Cell |
AVEO Pharmaceuticals, Inc. |
2016-05-24 | PHASE3 |
| NCT02354898 | COMPLETED | Advanced Solid Tumors; Hepatocellular Carcinoma |
Sumitomo Pharma Co., Ltd. |
2015-03 | PHASE1 |
| NCT03212625 | COMPLETED | Hepatocellular Carcinoma |
Korea University Guro Hospital |
2016-01-28 | PHASE4 |
| NCT02716766 | COMPLETED | Carcinoma, Hepatocellular; Secondary |
The University of Hong Kong |
2016-03 | PHASE2 |
| NCT00917462 | COMPLETED | Esophageal Cancer; Gastroesophageal Junction Cancer |
Memorial Sloan Kettering Cancer Center |
2009-06 | PHASE2 |
| NCT02474290 | COMPLETED | Acute Myeloid Leukemia; Hematopoietic Stem Cell Transplantation |
Nanfang Hospital, Southern Medical University |
2015-06-20 | PHASE2; PHASE3 |
| NCT01775501 | COMPLETED | Hepatocellular Cancer |
Massachusetts General Hospital |
2013-01 | PHASE2 |
| NCT02575339 | TERMINATED | Hepatocellular Carcinoma; Liver Cancer; HCC |
Kathy Miller |
2016-07-18 | PHASE1; PHASE2 |
| NCT02050919 | COMPLETED | Pleomorphic Rhabdomyosarcoma; Stage IIB Adult Soft Tissue Sarcoma AJCC v7; Stage III Adult Soft Tissue Sarcoma AJCC v7; Stage IV Adult Soft Tissue Sarcoma AJCC v7 |
OHSU Knight Cancer Institute |
2013-12-03 | PHASE2 |
| NCT01264705 | COMPLETED | Hepatocellular Carcinoma; Liver Cancer |
University of Texas Southwestern Medical Center |
2011-01 | PHASE1; PHASE2 |
| NCT02435433 | COMPLETED | Hepatocellular Carcinoma |
Eli Lilly and Company |
2015-07-20 | PHASE3 |
| NCT01217034 | UNKNOWN | Hepatocellular Carcinoma; Unresectable Hepatocellular Carcinoma; Carcinoma, Hepatocellular; Liver Neoplasm |
Kindai University |
2010-10 | PHASE2 |
| NCT01988493 | COMPLETED | Carcinoma, Hepatocellular |
Merck KGaA, Darmstadt, Germany |
2014-01-06 | PHASE1; PHASE2 |
| NCT01126645 | COMPLETED | Hepatocellular Carcinoma |
University of Magdeburg |
2010-12 | PHASE2 |
| NCT01636908 | COMPLETED | Cancer; Advanced Solid Tumors |
Amsterdam UMC, location VUmc |
2011-08 | |
| NCT01190241 | TERMINATED | Advanced Solid Tumors; Inoperable; Metastasis |
Amsterdam UMC, location VUmc |
2010-08 | |
| NCT02406521 | COMPLETED | Metastatic Renal Cell Carcinoma |
Dana-Farber Cancer Institute |
2015-04 | PHASE1 |
| NCT02406508 | WITHDRAWN | Hepatocellular Carcinoma (HCC) |
Delcath Systems Inc. |
2014-10 | PHASE2 |
| NCT02122003 | TERMINATED | Metastatic Renal Cell Carcinoma |
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
2016-09 | PHASE2 |
| NCT02971696 | COMPLETED | HCC |
Ain Shams University |
2016-12 | PHASE3 |
| NCT01908426 | COMPLETED | Hepatocellular Carcinoma |
Exelixis |
2013-09-26 | PHASE3 |
| NCT02425605 | COMPLETED | Hepatocellular Carcinoma |
Yonsei University |
2014-12-03 | PHASE2 |
| NCT02029157 | COMPLETED | Liver Cancer |
Kyowa Kirin Co., Ltd. |
2014-01 | PHASE3 |
| NCT02178358 | COMPLETED | Hepatocellular Carcinoma |
Eli Lilly and Company |
2014-08-08 | PHASE2 |
| NCT01409499 | COMPLETED | Hepatectomy; Hepatocellular Carcinoma; Sorafenib |
Sun Yat-sen University |
2011-01 | PHASE4 |
| NCT02129322 | WITHDRAWN | Hepatocellular Carcinoma |
Zhejiang University |
2015-07 | PHASE2 |
| NCT02013089 | UNKNOWN | Gastrointestinal Cancers |
Sun Yat-sen University |
2013-12 | |
| NCT01620216 | TERMINATED | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Chronic Myelomonocytic Leukemia; Recurrent Acute Lymphoblastic Leukemia; Recurrent Acute Myeloid Leukemia; Refractory Acute Lymphoblastic Leukemia; Refractory Acute Myeloid Leukemia |
OHSU Knight Cancer Institute |
2012-05-11 | PHASE2 |
| NCT02981498 | COMPLETED | Hepatocellular Carcinoma |
Sun Yat-sen University |
2015-06 | PHASE2 |
| NCT00943943 | COMPLETED | Acute Myelogenous Leukemia; Leukemia |
M.D. Anderson Cancer Center |
2010-10-29 | PHASE1 |
| NCT01405573 | TERMINATED | Advanced Adult Hepatocellular Carcinoma |
National Cancer Institute, Naples |
2011-07 | PHASE3 |
| NCT00244972 | COMPLETED | Advanced Malignant Neoplasm |
National Cancer Institute (NCI) |
2005-10 | PHASE1 |
| NCT01444807 | UNKNOWN | Metastatic Renal Cell Carcinoma |
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
2011-12 | PHASE2 |
| NCT00390325 | COMPLETED | Hereditary Thyroid Gland Medullary Carcinoma; Locally Advanced Thyroid Gland Medullary Carcinoma; Multiple Endocrine Neoplasia Type 2A; Multiple Endocrine Neoplasia Type 2B; Recurrent Thyroid Gland Medullary Carcinoma; Sporadic Thyroid Gland Medullary Carcinoma; Stage III Thyroid Gland Medullary Carcinoma AJCC v7; Stage IV Thyroid Gland Medullary Carcinoma AJCC v7; Stage IVA Thyroid Gland Medullary Carcinoma AJCC v7; Stage IVB Thyroid Gland Medullary Carcinoma AJCC v7; Stage IVC Thyroid Gland Medullary Carcinoma AJCC v7 |
National Cancer Institute (NCI) |
2006-11-03 | PHASE2 |
| NCT02323906 | TERMINATED | Carcinoma, Hepatocellular |
Celgene |
2015-01-16 | PHASE1 |
| NCT01762150 | COMPLETED | Renal Cell Carcinoma |
Peking University Cancer Hospital & Institute |
2011-06 | PHASE2 |
| NCT02150317 | UNKNOWN | Advanced Hepatocellular Carcinoma |
Eastern Hepatobiliary Surgery Hospital |
2014-01 | |
| NCT01849588 | TERMINATED | Hepatocellular Cancer |
Massachusetts General Hospital |
2013-05 | PHASE4 |
| NCT01833299 | COMPLETED | Hepatocellular Carcinoma; Face Cancer |
Sun Yat-sen University |
2010-01 | PHASE3 |
| NCT01761266 | COMPLETED | Hepatocellular Carcinoma (HCC) |
Eisai Limited |
2013-03-01 | PHASE3 |
| NCT02015728 | UNKNOWN | Recurrent Childhood Brain Tumor |
Seattle Children's Hospital |
2013-12 | |
| NCT02270788 | COMPLETED | Acute Myeloid Leukemia |
St. Jude Children's Research Hospital |
2015-04-02 | PHASE1 |
| NCT00622466 | TERMINATED | Breast Cancer |
University of Texas Southwestern Medical Center |
2008-04-23 | PHASE2 |
| NCT01534260 | COMPLETED | Acute Myeloid Leukemia |
Hamid Sayar |
2012-02-10 | PHASE1; PHASE2 |
| NCT02450149 | COMPLETED | Refractory Solid Tumors |
Samsung Medical Center |
2016-05-30 | |
| NCT02288507 | WITHDRAWN | Hepatocellular Cancer |
University of Hawaii |
2014-11 | PHASE1 |
| NCT02961998 | COMPLETED | Hepatocellular Carcinoma |
Sun Yat-sen University |
2015-07 | PHASE4 |
| NCT01306058 | COMPLETED | Hepatoma; Liver Neoplasms; Adenoma, Liver Cell; Carcinoma, Hepatocellular; Liver Neoplasms, Experimental |
National Cancer Institute (NCI) |
2011-02-11 | PHASE1; PHASE2 |
| NCT01377025 | UNKNOWN | Uveal Melanoma |
Prof. Dr. med. Max. E. Scheulen |
2011-06 | PHASE2 |
| NCT00881751 | COMPLETED | Liver Cancer |
Medical University of South Carolina |
2009-03 | PHASE2 |
| NCT01008566 | COMPLETED | Adult Hepatocellular Carcinoma; Advanced Adult Hepatocellular Carcinoma; Localized Non-Resectable Adult Liver Carcinoma; Recurrent Adult Liver Carcinoma |
National Cancer Institute (NCI) |
2009-08 | PHASE1 |
| NCT01183663 | COMPLETED | Advanced Cancers |
M.D. Anderson Cancer Center |
2010-08 | PHASE1 |
| NCT01687673 | COMPLETED | Hepatocellular Carcinoma |
University of California, San Francisco |
2012-10-05 | PHASE2 |
| NCT01482442 | COMPLETED | Liver Carcinoma |
Assistance Publique - Hôpitaux de Paris |
2011-12 | PHASE3 |
| NCT02538393 | COMPLETED | Biological Availability |
Bayer |
2015-11-20 | PHASE1 |
| NCT01774344 | COMPLETED | Carcinoma, Hepatocellular |
Bayer |
2013-05-14 | PHASE3 |
| NCT02101593 | COMPLETED | Hepatocellular Carcinoma |
Polaris Group |
2014-11 | PHASE1 |
| NCT01497444 | COMPLETED | Kidney Cancer; Liver Cancer |
Alliance for Clinical Trials in Oncology |
2012-05 | PHASE1 |
| NCT01754987 | COMPLETED | Metastatic Hepatocellular Carcinoma; Advanced Liver Cancer |
Thomas Jefferson University |
2012-09 | PHASE1; PHASE2 |
| NCT01683149 | COMPLETED | Solid Tumor |
H. Lee Moffitt Cancer Center and Research Institute |
2013-01 | PHASE1 |
| NCT01418729 | COMPLETED | Advanced Hepatocarcinoma |
Hospital Donostia |
2011-09 | PHASE2 |
| NCT01634893 | COMPLETED | Refractory or Relapsed Solid Tumors |
The University of Texas Health Science Center at San Antonio |
2012-06 | PHASE1 |
| NCT01480817 | TERMINATED | Hepatocellular Carcinoma |
Seoul National University Hospital |
2012-06 | PHASE2 |
| NCT04568330 | COMPLETED | Hepatocellular Carcinoma |
Taipei Veterans General Hospital, Taiwan |
2014-03-21 | |
| NCT01861314 | ACTIVE_NOT_RECRUITING | Acute Myeloid Leukemia; Acute Myeloid Leukemia Post Cytotoxic Therapy; Recurrent Adult Acute Myeloid Leukemia; Secondary Acute Myeloid Leukemia |
National Cancer Institute (NCI) |
2013-07-03 | PHASE1 |
| NCT01953406 | WITHDRAWN | Hepatocellular Carcinoma; Lung Metastasis |
Seoul National University Hospital |
2015-11 | PHASE2 |
| NCT02259647 | COMPLETED | Hepatocellular Carcinoma |
Institute of Liver and Biliary Sciences, India |
2014-10-01 | |
| NCT01471353 | COMPLETED | Colorectal Cancer Metastatic |
University of Florida |
2011-11 | PHASE2 |
| NCT02599337 | COMPLETED | Fasting |
Yabao Pharmaceutical Group |
2015-07 | PHASE1 |
| NCT01398501 | COMPLETED | Acute Myeloid Leukemia |
Massachusetts General Hospital |
2011-08 | PHASE1 |
| NCT01507064 | COMPLETED | Hepatocellular Carcinoma |
Cardarelli Hospital |
2012-01 | PHASE2 |
| NCT01585870 | COMPLETED | Neoplasms |
Bayer |
2012-07 | PHASE1 |
| NCT00326898 | COMPLETED | Clear Cell Renal Cell Carcinoma; Stage I Renal Cell Cancer AJCC v6 and v7; Stage II Renal Cell Cancer AJCC v7; Stage III Renal Cell Cancer AJCC v7 |
National Cancer Institute (NCI) |
2006-04-24 | PHASE3 |
| NCT01946529 | COMPLETED | Desmoplastic Small Round Cell Tumor; Ewing Sarcoma of Bone or Soft Tissue; Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor |
St. Jude Children's Research Hospital |
2013-12-27 | PHASE2 |
| NCT01915602 | COMPLETED | Carcinoma, Hepatocellular |
Bayer |
2013-09-27 | PHASE2 |
| NCT01271504 | COMPLETED | Hepatocellular Carcinoma |
Eisai Inc. |
2011-07-19 | PHASE1; PHASE2 |
| NCT00908167 | COMPLETED | Acute Myeloid Leukemia; Infantile Leukemia (Both AML and ALL); Myelodysplastic Syndrome; Myelodysplastic/Myeloproliferative Neoplasms; Biphenotypic Leukemia |
St. Jude Children's Research Hospital |
2009-09 | PHASE1 |
| NCT01194869 | TERMINATED | Breast Cancer |
Emory University |
2010-06 | PHASE2 |
| NCT01189370 | COMPLETED | Renal Cell Cancer |
University of Kansas Medical Center |
2008-06 | PHASE2 |
| NCT01715441 | COMPLETED | Metastatic Colorectal Cancer Patients With KRAS Mutated Tumors |
Institut du Cancer de Montpellier - Val d'Aurelle |
2012-09 | PHASE2 |
| NCT00844883 | COMPLETED | Hepatocellular Carcinoma; Hepatoma |
Yale University |
2009-02 | PHASE2 |
| NCT01777594 | COMPLETED | Advanced Adult Hepatocellular Carcinoma |
GenSpera, Inc. |
2013-01 | PHASE2 |
| NCT02227914 | WITHDRAWN | Advanced Hepatocellular Carcinoma |
Amgen |
2014-12 | PHASE1; PHASE2 |
| NCT00605566 | COMPLETED | Neuroendocrine Tumors |
University Health Network, Toronto |
2008-01 | PHASE2 |
| NCT02517736 | COMPLETED | Uveal Melanoma |
University Hospital, Caen |
2012-02 | PHASE2 |
| NCT01539018 | TERMINATED | Advanced Hepatocellular Carcinoma |
Egyptian Society of Liver Cancer |
2012-01 | PHASE2 |
| NCT01450384 | COMPLETED | Unspecified Adult Solid Tumor |
Virginia Commonwealth University |
2011-10 | PHASE1 |
| NCT01324076 | UNKNOWN | Liver Cancer |
University College, London |
2010-11 | PHASE3 |
| NCT01376453 | COMPLETED | Rectal Cancer |
H. Lee Moffitt Cancer Center and Research Institute |
2011-06 | PHASE1 |
| NCT00609934 | COMPLETED | Renal Cell Carcinoma |
University Health Network, Toronto |
2007-12 | PHASE1; PHASE2 |
| NCT01272557 | UNKNOWN | Liver Carcinoma |
PD Dr. med. Matthias Dollinger |
2010-12 | PHASE2 |
| NCT01342627 | TERMINATED | Metastatic Renal Cell Carcinoma |
Centro di Riferimento Oncologico - Aviano |
2010-10 | PHASE2 |
| NCT01320111 | COMPLETED | Metastatic Breast Cancer |
Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH |
2010-07-01 | PHASE2 |
| NCT01640665 | COMPLETED | Metastatic Breast Cancer; Gastrointestinal Tumors |
Yale University |
2012-07 | PHASE1 |
| NCT01801163 | WITHDRAWN | Hepatocellular Carcinoma |
Indiana University |
2012-02 | PHASE1 |
| NCT00987935 | COMPLETED | Carcinoma, Hepatocellular |
Boehringer Ingelheim |
2009-10 | PHASE2 |
| NCT01911273 | TERMINATED | Carcinoma, Hepatocellular |
Pfizer |
2013-10 | PHASE2 |
| NCT01076010 | COMPLETED | Advanced Renal Cell Carcinoma |
AVEO Pharmaceuticals, Inc. |
2010-03 | PHASE3 |
| NCT00436215 | COMPLETED | Ovarian Neoplasm; Fallopian Tube Cancer; Primary Peritoneal Cancer |
National Cancer Institute (NCI) |
2006-12-12 | PHASE2 |
| NCT01502410 | COMPLETED | Childhood Hepatocellular Carcinoma; Papillary Thyroid Cancer; Previously Treated Childhood Rhabdomyosarcoma; Recurrent Childhood Liver Cancer; Recurrent Childhood Rhabdomyosarcoma; Recurrent Thyroid Cancer; Recurrent Wilms Tumor and Other Childhood Kidney Tumors |
National Cancer Institute (NCI) |
2012-01 | PHASE2 |
| NCT01223027 | COMPLETED | Metastatic Renal Cell Carcinoma |
Novartis Pharmaceuticals |
2011-03 | PHASE3 |
| NCT01234337 | COMPLETED | Breast Cancer |
Bayer |
2011-02-21 | PHASE3 |
| NCT01556815 | UNKNOWN | PHENYTOIN/SORAFENIB [VA Drug Interaction]; Liver Neoplasms; Carcinoma, Hepatocellular; Digestive System Neoplasms; Neoplasms by Site; Liver Diseases; Adenocarcinoma; Carcinoma; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type; DOXORUBICIN/TRASTUZUMAB [VA Drug Interaction]; HBV |
Shandong Cancer Hospital and Institute |
2012-05 | PHASE2 |
| NCT01232296 | COMPLETED | Hepatocellular Carcinoma |
Novartis Pharmaceuticals |
2011-07 | PHASE2 |
| NCT01005797 | COMPLETED | Renal Cancer; Non Small Cell Lung Cancer (NSCLC); Soft Tissue Sarcoma |
Medical University of South Carolina |
2009-11 | PHASE1 |
| NCT00919061 | COMPLETED | Extrahepatic Bile Duct Cancer; Gallbladder Cancer |
Memorial Sloan Kettering Cancer Center |
2009-08 | PHASE2 |
| NCT01375569 | COMPLETED | Hepatocellular Carcinoma; Hepatocellular Cancer; Carcinoma, Hepatocellular |
National Cancer Institute (NCI) |
2011-06-22 | PHASE2 |
| NCT01029418 | TERMINATED | Hepatocellular Carcinoma |
National Cancer Centre, Singapore |
2009-11 | PHASE1; PHASE2 |
| NCT01245582 | WITHDRAWN | Hepatic Neoplasm Malignant |
Sanofi |
2011-07 | PHASE3 |
| NCT00933777 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific; Non-Small Cell Lung Cancer |
University of Cologne |
2009-07 | PHASE1 |
| NCT01605734 | UNKNOWN | PHENYTOIN/SORAFENIB [VA Drug Interaction]; Carcinoma, Hepatocellular |
Shandong Cancer Hospital and Institute |
2012-07 | PHASE2 |
| NCT01335074 | WITHDRAWN | Hepatocellular Carcinoma |
Philipps University Marburg |
2011-04 | PHASE1; PHASE2 |
| NCT00813293 | COMPLETED | Hepatocellular Cancer |
Beth Israel Deaconess Medical Center |
2009-06 | PHASE2 |
| NCT01903694 | COMPLETED | Child-Pugh A Hepatocellular Carcinoma |
Centre Hospitalier Universitaire Dijon |
2010-03 | PHASE3 |
| NCT01187212 | COMPLETED | Malignant Neoplasm of Stomach; Effects of Chemotherapy |
Asan Medical Center |
2010-08 | PHASE2 |
| NCT00837148 | COMPLETED | Sarcoma; Synovial Sarcoma; Leiomyosarcoma; Malignant Peripheral Nerve Sheath Tumor |
Memorial Sloan Kettering Cancer Center |
2009-02 | PHASE2 |
| NCT01108705 | TERMINATED | Carcinoma, Hepatocellular |
Bristol-Myers Squibb |
2010-05 | PHASE3 |
| NCT00392821 | COMPLETED | Kidney Cancer |
SCRI Development Innovations, LLC |
2006-12 | PHASE1; PHASE2 |
| NCT01035229 | COMPLETED | Carcinoma |
Novartis Pharmaceuticals |
2010-04 | PHASE3 |
| NCT01222676 | UNKNOWN | Bladder Cancer |
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
2010-10 | PHASE2 |
| NCT01214343 | UNKNOWN | Advanced Hepatocellular Carcinoma; Carcinoma; Carcinoma, Hepatocellular; Liver Neoplasms; Neoplasms |
Ministry of Health, Labour and Welfare, Japan |
2010-10 | PHASE3 |
| NCT00759928 | COMPLETED | Refractory Solid Tumors |
SCRI Development Innovations, LLC |
2008-10 | PHASE1 |
| NCT01159301 | TERMINATED | Adult Acute Basophilic Leukemia; Adult Acute Eosinophilic Leukemia; Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Minimally Differentiated Myeloid Leukemia (M0); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Blastic Phase Chronic Myelogenous Leukemia; Recurrent Adult Acute Myeloid Leukemia; Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2010-06 | PHASE1 |
| NCT00461851 | COMPLETED | Bladder Cancer |
Yale University |
2007-03 | PHASE2 |
| NCT00126594 | COMPLETED | Clear Cell Renal Cell Carcinoma; Recurrent Renal Cell Carcinoma; Stage IV Renal Cell Cancer |
National Cancer Institute (NCI) |
2005-06 | PHASE2 |
| NCT00976170 | COMPLETED | Hepatocellular Carcinoma |
Chugai Pharmaceutical |
2009-09 | PHASE1 |
| NCT00815295 | COMPLETED | Squamous Cell Cancer |
Duke University |
2008-01 | PHASE1; PHASE2 |
| NCT00949182 | COMPLETED | Liver Cancer |
Rutgers, The State University of New Jersey |
2009-07 | PHASE2 |
| NCT00825734 | COMPLETED | Metastatic Breast Cancer |
SCRI Development Innovations, LLC |
2009-03 | PHASE1; PHASE2 |
| NCT01258608 | COMPLETED | Carcinoma, Hepatocellular |
Human Genome Sciences Inc., a GSK Company |
2011-02-08 | PHASE1; PHASE2 |
| NCT01932177 | UNKNOWN | Metastatic or Locally Advanced Solid Tumors |
Hospices Civils de Lyon |
2013-04 | PHASE1 |
| NCT01498952 | COMPLETED | Unresectable or Metastatic Hepatocellular Carcinoma (HCC) |
MedImmune LLC |
2012-01-17 | PHASE1 |
| NCT01736878 | WITHDRAWN | Medullary Thyroid Carcinoma |
Eanm Research Ltd |
2012-10 | PHASE2 |
| NCT01159327 | TERMINATED | Small Cell Lung Cancer |
National Cancer Center, Korea |
2010-12 | PHASE2 |
| NCT01098760 | COMPLETED | Hepatocellular Carcinoma |
Bayer |
2010-08 | PHASE4 |
| NCT01425216 | TERMINATED | Keloids |
Tirgan, Michael H., M.D. |
2013-03 | PHASE2 |
| NCT01338857 | TERMINATED | neurofibromatosis1 (NF1); Recurrent or Progressive Optic Pathway Gliomas (OPG); Recurrent or Progressive Low-grade Glioma |
NYU Langone Health |
2011-04 | PHASE2 |
| NCT00418496 | COMPLETED | Renal Cancer; Melanoma |
Ohio State University Comprehensive Cancer Center |
2006-11-08 | PHASE1 |
| NCT00329719 | COMPLETED | Adult Glioblastoma; Adult Gliosarcoma; Recurrent Adult Brain Neoplasm |
National Cancer Institute (NCI) |
2006-03-24 | PHASE1; PHASE2 |
| NCT01078961 | COMPLETED | Melanoma |
Massachusetts General Hospital |
2010-09 | PHASE1 |
| NCT00939627 | COMPLETED | Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma; Recurrent Metastatic Squamous Neck Cancer With Occult Primary; Recurrent Salivary Gland Cancer; Recurrent Squamous Cell Carcinoma of the Hypopharynx; Recurrent Squamous Cell Carcinoma of the Larynx; Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity; Recurrent Squamous Cell Carcinoma of the Nasopharynx; Recurrent Squamous Cell Carcinoma of the Oropharynx; Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Recurrent Verrucous Carcinoma of the Larynx; Recurrent Verrucous Carcinoma of the Oral Cavity; Salivary Gland Squamous Cell Carcinoma; Stage IV Squamous Cell Carcinoma of the Hypopharynx; Stage IV Squamous Cell Carcinoma of the Nasopharynx; Stage IVA Salivary Gland Cancer; Stage IVA Squamous Cell Carcinoma of the Larynx; Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IVA Squamous Cell Carcinoma of the Oropharynx; Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Stage IVA Verrucous Carcinoma of the Larynx; Stage IVA Verrucous Carcinoma of the Oral Cavity; Stage IVB Salivary Gland Cancer; Stage IVB Squamous Cell Carcinoma of the Larynx; Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IVB Squamous Cell Carcinoma of the Oropharynx; Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Stage IVB Verrucous Carcinoma of the Larynx; Stage IVB Verrucous Carcinoma of the Oral Cavity; Stage IVC Salivary Gland Cancer; Stage IVC Squamous Cell Carcinoma of the Larynx; Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IVC Squamous Cell Carcinoma of the Oropharynx; Stage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Stage IVC Verrucous Carcinoma of the Larynx; Stage IVC Verrucous Carcinoma of the Oral Cavity; Tongue Cancer; Untreated Metastatic Squamous Neck Cancer With Occult Primary |
National Cancer Institute (NCI) |
2009-07 | PHASE2 |
| NCT01011010 | COMPLETED | Liver Cancer |
UNC Lineberger Comprehensive Cancer Center |
2009-07-22 | PHASE1 |
| NCT01348503 | TERMINATED | Hepatocellular Carcinoma |
Indiana University |
2011-05 | PHASE1 |
| NCT00811993 | TERMINATED | Neoplasms |
Hoffmann-La Roche |
2009-02 | PHASE1 |
| NCT00329641 | COMPLETED | Ciliary Body and Choroid Melanoma, Medium/Large Size; Extraocular Extension Melanoma; Iris Melanoma; Metastatic Intraocular Melanoma; Recurrent Intraocular Melanoma |
National Cancer Institute (NCI) |
2011-02 | PHASE2 |
| NCT00411671 | COMPLETED | Lung Cancer |
M.D. Anderson Cancer Center |
2006-11 | PHASE2 |
| NCT00495872 | COMPLETED | Solid Tumors |
M.D. Anderson Cancer Center |
2007-06 | PHASE1 |
| NCT00906373 | COMPLETED | Hepatocellular Carcinoma |
Eli Lilly and Company |
2009-05 | PHASE2 |
| NCT01171651 | COMPLETED | Carcinoma, Hepatocellular |
Jennerex Biotherapeutics |
2009-05-26 | PHASE2 |
| NCT00287495 | TERMINATED | Kaposi's Sarcoma; HHV-8; KSHV |
National Cancer Institute (NCI) |
2006-02-02 | PHASE1 |
| NCT01008917 | COMPLETED | Hepatocellular Carcinoma |
University of California, San Francisco |
2009-11-17 | PHASE1 |
| NCT00639262 | COMPLETED | Brain Metastases; Primary Brain Tumors |
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University |
2008-03 | PHASE1 |
| NCT00827177 | COMPLETED | Advanced Solid Tumors |
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA) |
2009-09 | PHASE1 |
| NCT01093222 | COMPLETED | Extrahepatic Bile Duct Adenocarcinoma; Gallbladder Adenocarcinoma; Gallbladder Adenocarcinoma With Squamous Metaplasia; Hilar Cholangiocarcinoma; Recurrent Extrahepatic Bile Duct Carcinoma; Recurrent Gallbladder Carcinoma; Undifferentiated Gallbladder Carcinoma; Unresectable Extrahepatic Bile Duct Carcinoma; Unresectable Gallbladder Carcinoma |
National Cancer Institute (NCI) |
2010-04 | PHASE2 |
| NCT00822848 | COMPLETED | Sarcoma |
OHSU Knight Cancer Institute |
2009-02 | PHASE1 |
| NCT00984282 | COMPLETED | Thyroid Neoplasms |
Bayer |
2009-10-15 | PHASE3 |
| NCT01009593 | TERMINATED | Hepatocellular Carcinoma Non-resectable; Hepatocellular Carcinoma Recurrent; Carcinoma, Hepatocellular; Liver Diseases; Neoplasms by Histologic Type; Digestive System Neoplasms; Carcinoma; Liver Neoplasms; Neoplasms; Neoplasms by Site; Digestive System Diseases; Adenocarcinoma; Neoplasms, Glandular and Epithelial |
Abbott |
2010-01 | PHASE3 |
| NCT00726986 | TERMINATED | Lung Cancer |
Afshin Dowlati, MD |
2008-07 | PHASE2 |
| NCT00875615 | COMPLETED | Liver Cancer |
University of Miami |
2008-12 | PHASE2 |
| NCT01303341 | ACTIVE_NOT_RECRUITING | Advanced Malignant Solid Neoplasm; Recurrent Melanoma; Refractory Malignant Solid Neoplasm; Stage III Cutaneous Melanoma AJCC v7; Stage IIIA Cutaneous Melanoma AJCC v7; Stage IIIB Cutaneous Melanoma AJCC v7; Stage IIIC Cutaneous Melanoma AJCC v7; Stage IV Cutaneous Melanoma AJCC v6 and v7 |
National Cancer Institute (NCI) |
2011-02-18 | PHASE1 |
| NCT01170104 | UNKNOWN | Hepatocellular Carcinoma |
Chung-Ang University |
2009-06 | PHASE2 |
| NCT01032850 | TERMINATED | Hepatocellular Carcinoma |
New Mexico Cancer Research Alliance |
2009-09 | PHASE2 |
| NCT00901901 | COMPLETED | Carcinoma, Hepatocellular |
Bayer |
2009-05-21 | PHASE3 |
| NCT00602862 | COMPLETED | Clear Cell Renal Cell Carcinoma |
Radboud University Medical Center |
2007-07 | |
| NCT00785226 | COMPLETED | Advanced Cancer |
Bayer |
2008-11 | PHASE1; PHASE2 |
| NCT00754923 | TERMINATED | Lung Cancer |
Ohio State University Comprehensive Cancer Center |
2008-10 | PHASE2 |
| NCT01445080 | COMPLETED | Blastic Phase; Childhood Acute Promyelocytic Leukemia With PML-RARA; Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Childhood Solid Neoplasm; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Juvenile Myelomonocytic Leukemia; Philadelphia Chromosome Negative, BCR-ABL1 Positive Chronic Myelogenous Leukemia; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Recurrent Disease |
National Cancer Institute (NCI) |
2006-05-30 | PHASE1; PHASE2 |
| NCT00863746 | COMPLETED | Carcinoma; Non-Small-Cell Lung |
Bayer |
2009-04 | PHASE3 |
| NCT00424385 | COMPLETED | Prostate Cancer |
Oncology Specialists, S.C. |
2007-01 | PHASE1 |
| NCT01851408 | WITHDRAWN | Melanoma; Recurrent Melanoma; Stage III Melanoma; Stage IV Melanoma |
National Cancer Institute (NCI) |
2006-04 | PHASE2 |
| NCT01308723 | COMPLETED | Carcinoma, Hepatocellular |
Hoffmann-La Roche |
2011-03 | PHASE1 |
| NCT00884416 | COMPLETED | Glioblastoma; Gliosarcoma; Anaplastic Astrocytoma; Anaplastic Oligoastrocytoma; Anaplastic Oligodendroglioma |
University Hospital, Geneva |
2009-03 | PHASE1 |
| NCT00699374 | TERMINATED | Carcinoma, Hepatocellular |
Pfizer |
2008-07 | PHASE3 |
| NCT00825955 | COMPLETED | Liver Cancer |
Bristol-Myers Squibb |
2009-02-17 | PHASE3 |
| NCT00474929 | COMPLETED | Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm |
Mayo Clinic |
2007-08-29 | PHASE1; PHASE2 |
| NCT01101906 | TERMINATED | Advanced Hepatocellular Carcinoma (HCC) |
Astellas Pharma Inc |
2011-01-10 | PHASE2 |
| NCT01041482 | UNKNOWN | Renal Cell Carcinoma |
Chinese Academy of Medical Sciences |
2008-11 | PHASE2 |
| NCT00687674 | TERMINATED | Multiple Myeloma and Plasma Cell Neoplasm |
Mayo Clinic |
2008-08 | PHASE1 |
| NCT00893373 | COMPLETED | Acute Myeloid Leukemia (AML) |
Technische Universität Dresden |
2009-03 | PHASE2 |
| NCT00714948 | TERMINATED | Bladder Cancer; URINARY BLADDER |
Memorial Sloan Kettering Cancer Center |
2008-07 | PHASE2 |
| NCT00635791 | COMPLETED | Malignant Solid Tumour; Renal Cell Carcinoma; Non Small Cell Lung Carcinoma |
University of Colorado, Denver |
2008-03 | PHASE1 |
| NCT00872014 | COMPLETED | Advanced Hepatocellular Carcinoma; Inoperable Hepatocellular Carcinoma |
Amgen |
2009-08 | PHASE2 |
| NCT01262482 | COMPLETED | Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (Relapsed After a Cisplatin Based Treatment) |
Grupo Espanol Multidisciplinario del Cancer Digestivo |
2008-10 | PHASE2 |
| NCT00810394 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
University of California, Davis |
2008-12 | PHASE2 |
| NCT00414388 | COMPLETED | Prostate Cancer |
Oncology Specialists, S.C. |
2006-12 | PHASE1; PHASE2 |
| NCT00131937 | COMPLETED | Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Hepatosplenic T-cell Lymphoma; Peripheral T-cell Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma |
National Cancer Institute (NCI) |
2005-10 | PHASE2 |
| NCT00398814 | COMPLETED | Renal Cancer; Tumors |
AEterna Zentaris |
2006-10 | PHASE1 |
| NCT01069328 | COMPLETED | Carcinoma, Non-Small-Cell Lung; Lung Cancer |
Bayer |
2006-07 | PHASE1 |
| NCT00548899 | COMPLETED | Breast Cancer |
GBG Forschungs GmbH |
2007-11 | PHASE2 |
| NCT00436579 | TERMINATED | Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2007-01 | PHASE1 |
| NCT00647426 | COMPLETED | Non-Small Cell Lung Cancer |
Abramson Cancer Center at Penn Medicine |
2007-11 | PHASE2 |
| NCT00791778 | COMPLETED | Ovarian Neoplasms |
Bayer |
2008-11 | PHASE2 |
| NCT00510289 | TERMINATED | Myelodysplastic Syndromes; Leukemia, Myelomonocytic, Chronic |
Duke University |
2006-07 | PHASE2 |
| NCT01215266 | TERMINATED | Bladder Cancer |
Association of Urologic Oncology (AUO) |
2006-10 | PHASE2 |
| NCT00828594 | TERMINATED | Hepatocellular Carcinoma |
Novartis Pharmaceuticals |
2008-12 | PHASE1 |
| NCT00303966 | TERMINATED | Refractory Chronic Lymphocytic Leukemia; Stage I Chronic Lymphocytic Leukemia; Stage II Chronic Lymphocytic Leukemia; Stage III Chronic Lymphocytic Leukemia; Stage IV Chronic Lymphocytic Leukemia |
National Cancer Institute (NCI) |
2005-11 | PHASE2 |
| NCT01337492 | TERMINATED | Carcinoma, Hepatocellular |
Case Comprehensive Cancer Center |
2010-09 | EARLY_PHASE1 |
| NCT00780169 | COMPLETED | Metastatic Colorectal Cancer |
Ottawa Hospital Research Institute |
2008-10 | PHASE1 |
| NCT00747799 | COMPLETED | Nasopharyngeal Neoplasms |
Sun Yat-sen University |
2009-01 | PHASE2 |
| NCT00618384 | TERMINATED | Hepatocellular Carcinoma |
Heinrich-Heine University, Duesseldorf |
2008-01 | PHASE2 |
| NCT00874874 | UNKNOWN | Sarcoma |
Centre Oscar Lambret |
2008-05 | PHASE2 |
| NCT00096200 | COMPLETED | Recurrent Fallopian Tube Carcinoma; Recurrent Ovarian Carcinoma; Recurrent Primary Peritoneal Carcinoma |
National Cancer Institute (NCI) |
2004-08 | PHASE2 |
| NCT00557830 | TERMINATED | Renal Cell Carcinoma |
Accelerated Community Oncology Research Network |
2008-01 | PHASE2 |
| NCT00956436 | COMPLETED | Hepatocellular Carcinoma |
Biogen |
2009-08 | PHASE1 |
| NCT00779311 | TERMINATED | Metastatic Colorectal Cancer |
Accelerated Community Oncology Research Network |
2008-10 | PHASE1 |
| NCT00964743 | TERMINATED | Neoplastic Meningitis |
H. Lee Moffitt Cancer Center and Research Institute |
2009-08 | |
| NCT00572078 | COMPLETED | SOLID TUMORS |
Safi Shahda |
2008-01-23 | PHASE1 |
| NCT00543335 | TERMINATED | Lung Cancer |
M.D. Anderson Cancer Center |
2008-01-25 | PHASE1 |
| NCT00789763 | COMPLETED | Pancreatic Cancer |
Grupo Espanol Multidisciplinario del Cancer Digestivo |
2007-12 | PHASE1 |
| NCT00610246 | COMPLETED | Cancer |
University Health Network, Toronto |
2007-05 | PHASE1 |
| NCT00667589 | TERMINATED | Hand-foot Skin Reaction; Rash |
Northwestern University |
2008-06 | PHASE2 |
| NCT00764972 | UNKNOWN | Metastatic Breast Cancer |
McGill University |
2007-10 | PHASE1; PHASE2 |
| NCT00941967 | COMPLETED | Liver Cancer |
Institut du Cancer de Montpellier - Val d'Aurelle |
2008-12 | PHASE2 |
| NCT00541021 | UNKNOWN | Pancreatic Cancer |
Institut Paoli-Calmettes |
2006-12 | PHASE3 |
| NCT01091207 | COMPLETED | Gastrointestinal Stromal Tumors |
Samsung Medical Center |
2009-11 | PHASE2 |
| NCT00281957 | COMPLETED | Recurrent Melanoma; Stage IV Melanoma |
National Cancer Institute (NCI) |
2007-08 | PHASE2 |
| NCT00823290 | TERMINATED | Hepatocellular Carcinoma |
University of Erlangen-Nürnberg Medical School |
2009-01 | PHASE1 |
| NCT00889057 | COMPLETED | Osteosarcoma |
Italian Sarcoma Group |
2008-01 | PHASE2 |
| NCT00654238 | COMPLETED | Metastatic Differentiated Thyroid Cancer; Metastatic Poorly Differentiated Thyroid Cancer; Metastatic Anaplastic Thyroid Cancer; Metastatic Medullary Thyroid Cancer |
University of Pennsylvania |
2006-02 | PHASE2 |
| NCT00696696 | COMPLETED | Pancreatic Cancer |
NYU Langone Health |
2007-09 | PHASE2 |
| NCT00839111 | UNKNOWN | Colorectal Neoplasms |
Fudan University |
2008-11 | PHASE2 |
| NCT00375310 | COMPLETED | Pancreatic Cancer; Adenocarcinoma of the Pancreas |
Indiana University |
2006-09 | PHASE1 |
| NCT00880542 | TERMINATED | Sarcoma |
Jonsson Comprehensive Cancer Center |
2008-08 | PHASE2 |
| NCT00621686 | COMPLETED | Brain and Central Nervous System Tumors |
Alliance for Clinical Trials in Oncology |
2008-09 | PHASE2 |
| NCT00933816 | COMPLETED | Hepatocellular Carcinoma |
Kindai University |
2009-07 | PHASE1; PHASE2 |
| NCT00131911 | COMPLETED | Gastrinoma; Glucagonoma; Insulinoma; Metastatic Gastrointestinal Carcinoid Tumor; Neuroendocrine Tumor; Pancreatic Polypeptide Tumor; Recurrent Gastrointestinal Carcinoid Tumor; Recurrent Islet Cell Carcinoma; Somatostatinoma; WDHA Syndrome |
National Cancer Institute (NCI) |
2005-06 | PHASE2 |
| NCT00999843 | UNKNOWN | Hepatocellular Carcinoma |
Fudan University |
2009-10 | PHASE1; PHASE2 |
| NCT00493636 | COMPLETED | Breast Cancer |
Accelerated Community Oncology Research Network |
2007-06 | PHASE2 |
| NCT01131689 | COMPLETED | Hepatocellular Carcinoma |
Samsung Medical Center |
2009-09 | PHASE1 |
| NCT00510250 | COMPLETED | Cancer of the Cervix |
University Health Network, Toronto |
2007-06 | PHASE1; PHASE2 |
| NCT00114244 | COMPLETED | Stage IV Pancreatic Cancer |
National Cancer Institute (NCI) |
2004-12 | PHASE2 |
| NCT00544609 | COMPLETED | Bladder Cancer |
Spanish Oncology Genito-Urinary Group |
2007-12 | PHASE1 |
| NCT00121264 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2005-03 | PHASE1 |
| NCT00634751 | COMPLETED | Pancreatic Neoplasms; Bile Duct Neoplasms |
University of Wisconsin, Madison |
2008-02 | PHASE1; PHASE2 |
| NCT00694291 | WITHDRAWN | Prostate Cancer |
Fox Chase Cancer Center |
2008-06 | PHASE2 |
| NCT00661830 | COMPLETED | Adenocarcinoma |
PD Dr Markus Möhler |
2008-05 | PHASE2 |
| NCT01157013 | COMPLETED | Hepatocellular Carcinoma |
Hospital Miguel Servet |
2009-01 | |
| NCT00687596 | TERMINATED | Hepatocellular Carcinoma |
Taiho Oncology, Inc. |
2008-08-01 | PHASE2 |
| NCT00303797 | COMPLETED | Refractory Chronic Lymphocytic Leukemia; Refractory Multiple Myeloma; Stage III Multiple Myeloma; Stage IV Chronic Lymphocytic Leukemia; Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2005-12 | PHASE1 |
| NCT00875745 | COMPLETED | Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Myelodysplastic Syndromes |
Indiana University |
2009-04 | PHASE1 |
| NCT00873002 | TERMINATED | Liver Cancer |
Case Comprehensive Cancer Center |
2009-03 | PHASE1 |
| NCT00449033 | COMPLETED | Carcinoma, Non-Small-Cell Lung |
Bayer |
2007-02 | PHASE3 |
| NCT00467025 | COMPLETED | Advanced Renal Cell Carcinoma |
Amgen |
2007-05 | PHASE2 |
| NCT00516828 | COMPLETED | Leukemia; Myelodysplastic Syndromes |
NCIC Clinical Trials Group |
2007-11-27 | PHASE1; PHASE2 |
| NCT00663741 | COMPLETED | Gastric Cancer |
Bayer |
2008-05 | PHASE1 |
| NCT00265798 | ACTIVE_NOT_RECRUITING | Gastrointestinal Stromal Tumor |
National Cancer Institute (NCI) |
2005-09-14 | PHASE2 |
| NCT00589420 | COMPLETED | Prostate Cancer |
Abramson Cancer Center at Penn Medicine |
2007-07-27 | PHASE2 |
| NCT00335764 | COMPLETED | Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma; Recurrent Adult Brain Tumor |
National Cancer Institute (NCI) |
2006-04 | PHASE1; PHASE2 |
| NCT00536575 | COMPLETED | Multiple Myeloma |
SCRI Development Innovations, LLC |
2007-11 | PHASE1; PHASE2 |
| NCT00826540 | COMPLETED | Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage IV Colon Cancer; Stage IV Rectal Cancer |
Alliance for Clinical Trials in Oncology |
2009-09 | PHASE2 |
| NCT00703365 | COMPLETED | Carcinoma, Hepatocellular |
Mahidol University |
2008-02 | PHASE2 |
| NCT00466232 | COMPLETED | Small Cell Carcinoma; Lung Cancer |
HealthPartners Institute |
2007-04 | PHASE1 |
| NCT00794859 | UNKNOWN | Mesothelioma |
King's College London |
2008-10 | PHASE2 |
| NCT00866320 | COMPLETED | Kidney Cancer |
Case Comprehensive Cancer Center |
2006-02 | PHASE2 |
| NCT00565370 | COMPLETED | Advanced Gastric Cancer |
Asan Medical Center |
2007-11 | PHASE1; PHASE2 |
| NCT00848640 | COMPLETED | Metastatic Renal Cell Carcinoma |
Egyptian Foundation For Cancer Research |
2008-10 | PHASE2 |
| NCT00794235 | COMPLETED | Melanoma Stage III or IV; No Prior Chemotherapy |
University of Zurich |
2008-12 | PHASE2 |
| NCT01128998 | COMPLETED | Advanced Solid Tumors |
National Health Research Institutes, Taiwan |
2009-11 | PHASE1 |
| NCT00496756 | TERMINATED | Kidney Cancer |
University of Nebraska |
2007-03-01 | PHASE2 |
| NCT00844688 | UNKNOWN | Hepatocellular Carcinoma |
Combined Military Hospital, Pakistan |
2008-09 | PHASE2 |
| NCT00786110 | UNKNOWN | Adrenocortical Carcinoma |
University of Turin, Italy |
2008-04 | PHASE2 |
| NCT00801801 | TERMINATED | Non Squamous Cell Lung Cancer; Non Small Cell Lung Cancer |
Francisco Robert,MD |
2008-01 | PHASE2 |
| NCT00672178 | TERMINATED | Renal Cell Carcinoma |
Duke University |
2008-03 | PHASE1; PHASE2 |
| NCT00387751 | COMPLETED | Recurrent Melanoma; Stage III Skin Melanoma; Stage IV Skin Melanoma |
National Cancer Institute (NCI) |
2006-08 | PHASE2 |
| NCT00478114 | COMPLETED | Renal Cell Carcinoma |
Mahidol University |
2007-05 | PHASE3 |
| NCT00217399 | COMPLETED | Recurrent Breast Cancer; Stage IV Breast Cancer |
National Cancer Institute (NCI) |
2005-06 | PHASE1; PHASE2 |
| NCT00538005 | UNKNOWN | Melanoma (Skin) |
San Diego Pacific Oncology & Hematology Associates |
2007-05 | PHASE1; PHASE2 |
| NCT00494299 | COMPLETED | Carcinoma, Hepatocellular |
Bayer |
2006-04 | PHASE3 |
| NCT00854620 | COMPLETED | Carcinoma, Renal Cell; Kidney Disease; Kidney Cancer |
Stanford University |
2007-12 | PHASE2 |
| NCT00547443 | WITHDRAWN | Lung Cancer |
University of Texas Southwestern Medical Center |
2007-07 | PHASE1; PHASE2 |
| NCT00373373 | COMPLETED | Acute Myeloid Leukemia |
University Hospital Muenster |
2006-09 | PHASE2 |
| NCT00678288 | TERMINATED | Carcinoma, Renal Cell |
Bayer |
2008-04 | PHASE2 |
| NCT00562913 | COMPLETED | Cancer |
Bayer |
2007-12 | PHASE1 |
| NCT00613145 | COMPLETED | Refractory Malignancy |
SCRI Development Innovations, LLC |
2008-02 | PHASE1 |
| NCT00541840 | UNKNOWN | Soft Tissue Sarcoma |
Grupo Espanol de Investigacion en Sarcomas |
2007-10 | PHASE1; PHASE2 |
| NCT00562523 | COMPLETED | Neoplasms |
Bayer |
2007-11 | PHASE1 |
| NCT00632541 | TERMINATED | Metastatic Breast Cancer |
Hoosier Cancer Research Network |
2007-10 | PHASE2 |
| NCT00600015 | COMPLETED | Non-Small Cell Lung Cancer |
SCRI Development Innovations, LLC |
2008-02 | PHASE2 |
| NCT00595985 | TERMINATED | Gastric Cancer |
Fudan University |
2007-07 | PHASE2 |
| NCT00478374 | COMPLETED | Hepatocellular Carcinoma |
University of Bern |
2007-05 | PHASE1 |
| NCT00602576 | COMPLETED | Melanoma (Skin) |
Abramson Cancer Center at Penn Medicine |
2005-01-01 | PHASE2 |
| NCT00105443 | COMPLETED | Carcinoma, Hepatocellular |
Bayer |
2005-03 | PHASE3 |
| NCT00722969 | UNKNOWN | Non-Small Cell Lung Cancer |
Universitair Ziekenhuis Brussel |
2007-11 | PHASE2 |
| NCT00492986 | COMPLETED | Carcinoma, Renal Cell |
Bayer |
2005-10 | PHASE3 |
| NCT00498836 | COMPLETED | Malignant Melanoma |
Clavis Pharma |
2007-03 | PHASE2 |
| NCT00182689 | COMPLETED | Extensive Stage Small Cell Lung Cancer; Recurrent Small Cell Lung Cancer |
National Cancer Institute (NCI) |
2005-07 | PHASE2 |
| NCT00445042 | COMPLETED | Carcinoma, Renal Cell |
The Methodist Hospital Research Institute |
2005-11 | PHASE2 |
| NCT00473486 | TERMINATED | Carcinoma, Non-Small-Cell Lung |
University Hospital Muenster |
2007-05 | PHASE1; PHASE2 |
| NCT00606125 | COMPLETED | Neoplasms |
Bayer |
2007-05 | PHASE1 |
| NCT00452387 | TERMINATED | Metastatic Prostate Cancer |
Accelerated Community Oncology Research Network |
2007-05 | PHASE2 |
| NCT00490685 | COMPLETED | Carcinoma, Hepatocellular |
Istituto Clinico Humanitas |
2007-04 | PHASE2 |
| NCT00586495 | COMPLETED | Carcinoma, Renal Cell |
Bayer |
2005-12 | PHASE2 |
| NCT00253370 | COMPLETED | Adenocarcinoma of the Gastroesophageal Junction; Metastatic Gastric Cancer; Advanced Unresectable Gastric Cancer |
National Cancer Institute (NCI) |
2005-10 | PHASE2 |
| NCT00586105 | COMPLETED | Carcinoma, Renal Cell |
Bayer |
2005-12 | PHASE3 |
| NCT00558636 | TERMINATED | Carcinoma, Non-Small-Cell Lung |
Bayer |
2007-09 | PHASE3 |
| NCT00217620 | COMPLETED | Sarcoma |
National Cancer Institute (NCI) |
2006-03 | PHASE2 |
| NCT00417248 | TERMINATED | Non-Small Cell Lung Cancer |
Nasser Hanna, M.D. |
2007-06 | PHASE1; PHASE2 |
| NCT00496301 | COMPLETED | Carcinoma, Renal Cell |
Spanish Oncology Genito-Urinary Group |
2006-11 | PHASE2 |
| NCT00044512 | COMPLETED | Carcinoma, Hepatocellular |
Bayer |
2002-08 | PHASE2 |
| NCT00544167 | COMPLETED | Breast Cancer |
SCRI Development Innovations, LLC |
2007-05 | |
| NCT00619996 | COMPLETED | Prostate Cancer |
Italian Trial in Medical Oncology |
2007-03 | PHASE2 |
| NCT00330421 | COMPLETED | Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Metastatic Osteosarcoma; Recurrent Adult Soft Tissue Sarcoma; Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Recurrent Osteosarcoma; Stage I Adult Soft Tissue Sarcoma; Stage II Adult Soft Tissue Sarcoma; Stage III Adult Soft Tissue Sarcoma; Stage IV Adult Soft Tissue Sarcoma |
National Cancer Institute (NCI) |
2006-06 | PHASE2 |
| NCT00619541 | COMPLETED | Hepatocellular Carcinoma |
Italian Trial in Medical Oncology |
2007-01 | PHASE2 |
| NCT00119249 | COMPLETED | Stage III Melanoma; Stage IV Melanoma |
National Cancer Institute (NCI) |
2005-06 | PHASE2 |
| NCT00253578 | COMPLETED | Refractory Multiple Myeloma |
National Cancer Institute (NCI) |
2006-03 | PHASE2 |
| NCT00090545 | COMPLETED | Prostate Cancer |
National Cancer Institute (NCI) |
2004-09-01 | PHASE2 |
| NCT00111020 | COMPLETED | Carcinoma, Renal Cell |
Bayer |
2005-06 | PHASE3 |
| NCT00107432 | COMPLETED | Epithelial Mesothelioma; Recurrent Malignant Mesothelioma; Sarcomatous Mesothelioma; Stage IA Malignant Mesothelioma; Stage IB Malignant Mesothelioma; Stage II Malignant Mesothelioma; Stage III Malignant Mesothelioma; Stage IV Malignant Mesothelioma |
National Cancer Institute (NCI) |
2004-10 | PHASE2 |
| NCT00301847 | COMPLETED | Kidney Cancer; Metastatic Cancer |
National Cancer Institute (NCI) |
2005-11 | PHASE2 |
| NCT00609401 | COMPLETED | Metastatic Disease; Renal Cell Carcinoma |
Italian Trial in Medical Oncology |
2006-11 | PHASE2 |
| NCT00118170 | COMPLETED | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Nodal Marginal Zone B-cell Lymphoma; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Refractory Multiple Myeloma; Splenic Marginal Zone Lymphoma; Stage II Multiple Myeloma; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Multiple Myeloma; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma; Unspecified Adult Solid Tumor, Protocol Specific; Waldenström Macroglobulinemia |
National Cancer Institute (NCI) |
2004-10 | PHASE1 |
| NCT00255658 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2005-09 | PHASE1 |
| NCT00131989 | COMPLETED | Adult Acute Basophilic Leukemia; Adult Acute Eosinophilic Leukemia; Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Minimally Differentiated Myeloid Leukemia (M0); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia |
National Cancer Institute (NCI) |
2005-06 | PHASE1 |
| NCT00492752 | COMPLETED | Carcinoma, Hepatocellular |
Bayer |
2005-10 | PHASE3 |
| NCT00259129 | COMPLETED | Neoplasms |
Bayer |
2005-08 | PHASE1 |
| NCT00606866 | COMPLETED | Metastatic Renal Cell Carcinoma |
University of Chicago |
2004-07 | PHASE3 |
| NCT00110994 | COMPLETED | Cancer; Melanoma |
Bayer |
2005-04 | PHASE2 |
| NCT00093457 | COMPLETED | Prostate Cancer |
NCIC Clinical Trials Group |
2004-08-10 | PHASE2 |
| NCT00117637 | COMPLETED | Carcinoma, Renal Cell |
Bayer |
2005-06 | PHASE2 |
| NCT00073307 | COMPLETED | Carcinoma, Renal Cell |
Bayer |
2003-11 | PHASE3 |
| NCT00096434 | COMPLETED | Male Breast Cancer; Recurrent Breast Cancer; Stage IV Breast Cancer |
National Cancer Institute (NCI) |
2004-09 | PHASE2 |
| NCT00661375 | COMPLETED | Carcinoma, Renal Cell |
Bayer |
2004-11 | PHASE2 |
| NCT00098618 | TERMINATED | Clear Cell Renal Cell Carcinoma; Papillary Renal Cell Carcinoma; Recurrent Renal Cell Cancer; Stage III Renal Cell Cancer; Stage IV Renal Cell Cancer |
National Cancer Institute (NCI) |
2004-10 | PHASE2 |
| NCT00101400 | COMPLETED | Breast Neoplasms; Breast Cancer |
Bayer |
2004-02 | PHASE2 |
| NCT00095459 | COMPLETED | Neoplasms |
National Cancer Institute (NCI) |
2004-11-02 | PHASE1 |
| NCT00095966 | COMPLETED | Adenocarcinoma of the Pancreas; Recurrent Pancreatic Cancer; Stage II Pancreatic Cancer; Stage III Pancreatic Cancer; Stage IV Pancreatic Cancer |
National Cancer Institute (NCI) |
2004-09 | PHASE2 |
| NCT00101413 | COMPLETED | Cancer; Carcinoma, Non-Small Cell Lung |
Bayer |
2004-04 | PHASE2 |
| NCT00657254 | COMPLETED | Neoplasm; Metastasis |
Bayer |
2002-12 | PHASE2 |
| NCT00941863 | COMPLETED | Carcinoma |
Bayer |
2002-07 | PHASE1 |
| NCT00661180 | COMPLETED | Chronic Myelogenous Leukemia |
Bayer |
2004-01 | PHASE2 |
| NCT00627835 | WITHDRAWN | Locally Advanced Squamous Cell Carcinomas of the Head and Neck (SCCHN) |
British Columbia Cancer Agency |
PHASE1 | |
| NCT00861419 | COMPLETED | Advanced Solid Tumors |
Amgen |
2005-12 | PHASE1 |
| NCT00352859 | TERMINATED | Carcinoma, Renal Cell |
Bayer |
2006-08 | PHASE4 |
| NCT00887107 | COMPLETED | Thyroid Cancer |
Leiden University Medical Center |
2007-10 | PHASE2 |
| NCT00079612 | COMPLETED | Carcinoma, Renal Cell |
Bayer |
2002-09 | PHASE2 |
| NCT00119639 | COMPLETED | Kidney Diseases |
Bayer |
2005-06 | PHASE1 |
| NCT00464919 | COMPLETED | Hepatocellular Carcinoma |
National Taiwan University Hospital |
2007-04 | PHASE2 |
(data from https://clinicaltrials.gov, updated on 2026-08-26)
Check the
Sorafenib (BAY 43-9006)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
- Sorafenib (BAY 43-9006) Mechanism of Action: Raf Inhibition in Hepatocellular Carcinoma Cell Research
- Sorafenib (BAY 43-9006): Selectivity & Specificity
- Sorafenib (BAY 43-9006) Working Concentration | Cell Culture | Treatment
- Sorafenib (BAY 43-9006) Solubility in DMSO
- Sorafenib (BAY 43-9006) Stock Solution
- Sorafenib (BAY 43-9006) Storage
- Sorafenib (BAY 43-9006) Stability
- Sorafenib (BAY 43-9006) Combination Database
- Sorafenib (BAY 43-9006) Molecular Weight
- Sorafenib (BAY 43-9006) SMILES
- Sorafenib (BAY 43-9006) CAS Number
- Sorafenib (BAY 43-9006) Chemical Structure (2D and 3D)
- Sorafenib (BAY 43-9006) IC50 for Cell-based and Cell-free Assays
- Sorafenib (BAY 43-9006) Sigma (SML2653)? Try a better option.
- Sorafenib (BAY 43-9006) MedChemExpress (HY-10201)? Try a better option.
- Sorafenib (BAY 43-9006) Cayman (10009644)? Try a better option.
- Sorafenib (BAY 43-9006) APExBIO (A3009)? Try a better option.
- Sorafenib (BAY 43-9006) AbMole (M3026)? Try a better option.
- Sorafenib (BAY 43-9006) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.