Sodium oxamate is a competitive LDHA inhibitor. It affects PI3K/Akt/mTOR and HIF1α signaling pathways by blocking pyruvate-to-lactate conversion and reducing histone lactylation, effectively inhibiting tumor cell proliferation and migration, and promoting apoptosis.
Sodium oxamate IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Sodium oxamate Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.