Home Biosimilar Antibodies Neuronal Signaling MAO Simtuzumab (Anti-LOXL2)
For research use only. Not for use in humans.

Simtuzumab (Anti-LOXL2)

Synonyms: AB 0024, GS 6624

Simtuzumab (Anti-LOXL2) is a monoclonal antibody directed against Lysyl oxidase like-2 (LOXL2) with potential antineoplastic activity. MW: 145.5 kD.

Simtuzumab (Anti-LOXL2)

1 Citation

The Nobel Prize

17 Nobel Prize winners have used Selleck products

Shimon Sakaguchi

Nature Communications 2025,16, Article number:1325

David Baker

Dev Cell 2023, 58(20):2163-2180.e9.

David Julius

Cell 2017, 185-198.e16

Michael Houghton

Cell Chem Biol, 2020, 27(7):780-792.e5

Charles M. Rice

Cell 2018, 172(3):423-438.e25

Quality Control

Batch: A240801 Purity: 99% Protein concentration: 11.22mg/ml Endotoxin Level: ＜1EU/mg
99

Specificity

Name Citation MAO-A MAO-B MAO Others
Moclobemide (Ro 111163) 6
Vafidemstat 0 LSD1/KDM1A
Norharmane 1
MAO-B-IN-2 0 BChE
Xanthoangelol 1 dopamine-beta-hydroxylase
4-Hydroxyderricin 0
Toloxatone (MD69276) 0
TB5 0
Lazabemide 0
Harmine 5 PPARγ
Isatin 2
Sennoside A 2
Paeonol 2
Glycyrrhizin (Glycyrrhizic Acid, NSC 167409) 44 HMGB1,11 beta-hydroxysteroid dehydrogenase
Harmane 0
Iproniazid phosphate 0
Myristicin 0 CYP1A2
Hypericin 1 P450,Telomerase,Reverse transcriptase
Eprobemide 0
Iproniazid 0
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Simtuzumab (Anti-LOXL2) is a monoclonal antibody directed against Lysyl oxidase like-2 (LOXL2) with potential antineoplastic activity. MW: 145.5 kD.

Product Details

CAS No. 1318075-13-6
Molecular Weight 145.5 kDa
Isotype Human IgG4SP
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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