Clinical Trials
Sildenafil has an extensive research history spanning early- to late-phase evaluations across numerous clinical trials sponsored by academic institutions, hospital networks, and government entities. These studies reflect varied recruitment statuses—including recruiting, active, completed, terminated, and withdrawn—to evaluate indications such as erectile dysfunction, pulmonary hypertension, birth asphyxia, neurogenic bladder management, and post-cardiac surgery pulmonary hemodynamics.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT06800092 | NOT_YET_RECRUITING | Cancer |
The University of Texas Medical Branch, Galveston |
2027-06-15 | PHASE2; PHASE3 |
| NCT06123156 | RECRUITING | Rectal Cancer |
University Hospital, Rouen |
2025-09-25 | PHASE3 |
| NCT06510322 | RECRUITING | Vascular Diseases |
Montefiore Medical Center |
2025-03-12 | EARLY_PHASE1 |
| NCT06649539 | ACTIVE_NOT_RECRUITING | Peyronie Disease |
Charitable Union for the Research and Education of Peyronie's Disease |
2024-10-11 | PHASE4 |
| NCT07713914 | RECRUITING | Pulmonary Arterial Hypertension (PAH) |
University of Sao Paulo General Hospital |
2026-07-22 | PHASE4 |
| NCT07039760 | NOT_YET_RECRUITING | Brain Tumor |
Washington University School of Medicine |
2026-08-31 | EARLY_PHASE1 |
| NCT05782244 | RECRUITING | Traumatic Brain Injury |
University of Pennsylvania |
2024-07-02 | PHASE2 |
| NCT06098833 | RECRUITING | Neonatal Encephalopathy |
Pia Wintermark |
2024-07-01 | PHASE2 |
| NCT06810284 | NOT_YET_RECRUITING | Hypoxic-Ischemic Encephalopathy |
Assistance Publique - Hôpitaux de Paris |
2026-10 | PHASE2 |
| NCT07647003 | NOT_YET_RECRUITING | Hypertension |
NuSirt Biopharma |
2026-10-15 | PHASE2 |
| NCT07508358 | NOT_YET_RECRUITING | Dysmenorrhea; Menstrual Pain |
Kevin Hellman |
2026-05 | PHASE1 |
| NCT05061368 | RECRUITING | Chronic Obstructive Pulmonary Disease |
University of Alberta |
2022-03-01 | PHASE2 |
| NCT06875258 | RECRUITING | Erectile Dysfunction Following Radical Prostatectomy |
The Netherlands Cancer Institute |
2024-01-15 | PHASE4 |
| NCT06324396 | RECRUITING | Fontan Circulation |
Children's Mercy Hospital Kansas City |
2024-03-01 | PHASE1 |
| NCT04565925 | RECRUITING | Spinal Cord Injuries; Urinary Incontinence |
The University of Texas Medical Branch, Galveston |
2021-07-07 | PHASE2 |
| NCT07391579 | RECRUITING | Erectile Dysfunctions |
Mansoura University |
2025-12-01 | PHASE4 |
| NCT06954597 | RECRUITING | Digital Ulcers in Systemic Sclerosis |
Topadur Pharma AG |
2025-02-04 | PHASE2 |
| NCT07177326 | NOT_YET_RECRUITING | Erectile Dysfunction |
Assiut University |
2025-10-01 | PHASE3 |
| NCT07732387 | NOT_YET_RECRUITING | Erectile Dysfunctions; Healthy Volunteer |
Yanping Kong |
2026-08-01 | PHASE1 |
| NCT04797286 | RECRUITING | Scleroderma; Mildly Elevated Pulmonary Pressures |
Johns Hopkins University |
2021-09-20 | PHASE2 |
| NCT06377098 | WITHDRAWN | Neonatal Asphyxia; Intrapartum Fetal Distress; Development, Infant; Intrapartum Asphyxia |
University of Alabama at Birmingham |
2025-05-01 | PHASE3 |
| NCT06715280 | RECRUITING | Chronic Thromboembolic Pulmonary Hypertension |
Chinese University of Hong Kong |
2024-07-25 | PHASE4 |
| NCT07293156 | COMPLETED | Diabete Mellitus; Erectile Dysfunction Associated With Type 2 Diabetes Mellitus; Pilates Exercise; Pelvic Floor Muscle Exercise |
Benha University |
2025-12-15 | |
| NCT04912726 | WITHDRAWN | Hypertension, Pulmonary |
Universidad del Norte |
2025-01-01 | |
| NCT07290400 | NOT_YET_RECRUITING | Erectile Dysfunction |
Aspargo Labs, Inc |
2026-04-15 | PHASE2 |
| NCT03997097 | WITHDRAWN | Single-ventricle; Pulmonary Hypertension; Univentricular Heart |
University Hospital, Montpellier |
2023-06-01 | PHASE3 |
| NCT06522854 | WITHDRAWN | Intrapartum Fetal Distress; Neonatal Asphyxia; Intrapartum Asphyxia; Instrumental Delivery; Affecting Fetus |
University of Alabama at Birmingham |
2025-05-01 | PHASE3 |
| NCT07302698 | NOT_YET_RECRUITING | Healthy Volunteers |
Aspargo Labs, Inc |
2026-03-15 | PHASE1 |
| NCT06839651 | NOT_YET_RECRUITING | Erectile Dysfunctions |
Indonesia University |
2025-04-21 | PHASE1 |
| NCT07462260 | RECRUITING | Pulmonary Hypertension; Rheumatic Valvular Heart Disease |
Sindh Institute of Cardiovascular Diseases |
2025-08-01 | PHASE2; PHASE3 |
| NCT05201144 | RECRUITING | Congenital Diaphragmatic Hernia; Pulmonary Hypertension |
University of Utah |
2022-09-15 | PHASE2 |
| NCT07117383 | NOT_YET_RECRUITING | Erectile Dysfunction |
Aspargo Labs, Inc |
2026-01 | PHASE1 |
| NCT07231185 | NOT_YET_RECRUITING | Erectile Dysfunction |
Aspargo Labs, Inc |
2026-01 | PHASE2 |
| NCT06872866 | RECRUITING | Erectile Dysfunction |
Aspargo Labs, Inc |
2025-04-15 | PHASE1 |
| NCT04039464 | COMPLETED | Pediatric Pulmonary Hypertension |
Johns Hopkins University |
2022-08-01 | PHASE3 |
| NCT07769476 | COMPLETED | Polycystic Ovarian Syndrome (PCOS); Polyendocrine Metabolic Ovarian Syndrome (PMOS) |
Nishtar Medical University |
2025-07-01 | PHASE4 |
| NCT03686306 | ACTIVE_NOT_RECRUITING | Peripheral Artery Disease |
Rennes University Hospital |
2021-11-24 | PHASE3 |
| NCT07135037 | RECRUITING | Oligohydramnios |
Kafrelsheikh University |
2024-09-01 | PHASE2 |
| NCT07245875 | COMPLETED | Erectile Dysfunction; Diabetes Mellitus Type 2 |
Indonesia University |
2024-04-12 | |
| NCT06778330 | COMPLETED | Heart Failure NYHA Class II |
Fayoum University |
2025-01-20 | |
| NCT02682147 | ACTIVE_NOT_RECRUITING | Emphysema |
Eric A. Hoffman |
2017-07-10 | PHASE4 |
| NCT04898114 | RECRUITING | Persistent Pulmonary Hypertension of Newborn |
Sohag University |
2021-06-02 | PHASE1; PHASE2 |
| NCT06289881 | UNKNOWN | Healthy Subjects |
Bio-innova Co., Ltd |
2025-02-04 | PHASE1 |
| NCT03142568 | COMPLETED | Bronchopulmonary Dysplasia |
University of North Carolina, Chapel Hill |
2018-04-02 | PHASE2 |
| NCT06782659 | NOT_YET_RECRUITING | Erectile Dysfunction |
Aspargo Labs, Inc |
2025-01 | PHASE1 |
| NCT05275725 | ACTIVE_NOT_RECRUITING | Birth Asphyxia |
Pia Wintermark |
2022-07-01 | PHASE1 |
| NCT06178523 | COMPLETED | Unexplained Infertility |
Batterjee Medical College |
2024-01-01 | PHASE4 |
| NCT04447989 | COMPLETED | Bronchopulmonary Dysplasia of Newborn |
Christoph Hornik |
2021-05-27 | PHASE2 |
| NCT05490680 | COMPLETED | Erectile Dysfunction |
IBSA Institut Biochimique SA |
2024-01-26 | PHASE3 |
| NCT04344678 | WITHDRAWN | Major Depressive Disorder |
Sadat City University |
2020-01-01 | |
| NCT06237751 | UNKNOWN | Central Venous Pressure; Hepatectomy; Hemodynamics Instability; Sildenafil |
First People's Hospital of Chenzhou |
2024-02-01 | |
| NCT06860399 | COMPLETED | PPHN |
Damascus University |
2023-05-01 | PHASE1; PHASE2 |
| NCT03382106 | COMPLETED | Emphysema |
Eric A. Hoffman |
2018-03-19 | PHASE4 |
| NCT05196308 | COMPLETED | Erectile Dysfunction |
Assistance Publique - Hôpitaux de Paris |
2022-03-18 | PHASE2 |
| NCT04985929 | COMPLETED | Healthy |
University of Alberta |
2021-07-01 | PHASE2 |
| NCT04039087 | COMPLETED | Cystic Fibrosis |
National Jewish Health |
2019-09-05 | PHASE2; PHASE3 |
| NCT06562036 | COMPLETED | Persistent Pulmonary Hypertension of the Newborn |
Muhammad Aamir Latif |
2023-12-01 | |
| NCT04538976 | COMPLETED | Acute Exacerbation of COPD |
Chronic Obstructive Pulmonary Disease Trial Network, Denmark |
2020-02-01 | PHASE4 |
| NCT05765487 | COMPLETED | Sexual Arousal Disorder |
Daré Bioscience, Inc. |
2023-05-13 | PHASE1 |
| NCT05669885 | UNKNOWN | Post-Traumatic Headache |
Danish Headache Center |
2023-01-02 | |
| NCT03402191 | UNKNOWN | Thalassemia |
Sherief Abd-Elsalam |
2016-07 | PHASE4 |
| NCT05971667 | UNKNOWN | IVF |
Beni-Suef University |
2023-07-30 | PHASE2; PHASE3 |
| NCT05889455 | COMPLETED | Migraine Without Aura |
Danish Headache Center |
2023-04-20 | |
| NCT05951413 | UNKNOWN | IVF |
Beni-Suef University |
2023-06-30 | PHASE2; PHASE3 |
| NCT05556083 | UNKNOWN | Premature Ejaculation |
Al-Azhar University |
2022-10-01 | PHASE2 |
| NCT05584956 | UNKNOWN | Beta Thalassemia With Increased Tricuspid Regurgitant Jet Velocity |
Tanta University |
2022-07-08 | PHASE3 |
| NCT05466695 | UNKNOWN | Erectile Dysfunction and Neutrophil Lymphocyte Ratio |
Assiut University |
2022-08-01 | EARLY_PHASE1 |
| NCT04908657 | UNKNOWN | Liver Fibrosis |
National Taiwan University Hospital |
2017-07-03 | PHASE4 |
| NCT04704440 | COMPLETED | Hypertension, Pulmonary |
University of Zurich |
2021-02-01 | |
| NCT04715113 | COMPLETED | Hypertension, Pulmonary |
University of Zurich |
2021-02-01 | |
| NCT04697862 | COMPLETED | Hypertension, Pulmonary |
University of Zurich |
2021-02-01 | |
| NCT04706546 | COMPLETED | Hypertension, Pulmonary |
University of Zurich |
2021-02-01 | |
| NCT05684289 | COMPLETED | Healthy Participants |
Bristol-Myers Squibb |
2023-01-03 | PHASE1 |
| NCT06565728 | COMPLETED | Fetal Growth Retardation |
Cairo University |
2022-11-03 | PHASE1 |
| NCT03945643 | COMPLETED | Patent Foramen Ovale; Intrapulmonary Arteriovenous Anastamosis |
University of Oregon |
2019-07-01 | EARLY_PHASE1 |
| NCT05753098 | COMPLETED | Subfertility, Female |
Beni-Suef University |
2021-01-15 | PHASE4 |
| NCT03199612 | COMPLETED | Thrombosis; Hemolysis |
Montefiore Medical Center |
2019-06-03 | EARLY_PHASE1 |
| NCT04122105 | WITHDRAWN | Renal Transplant Failure |
University of British Columbia |
2021-04-01 | |
| NCT04525495 | UNKNOWN | Neonates and Preterm Infants |
Seoul National University Hospital |
2020-04-01 | PHASE2 |
| NCT05183334 | UNKNOWN | Premature Ejaculation |
Assiut University |
2021-12-30 | PHASE4 |
| NCT06064448 | COMPLETED | Chronic Prostatitis With Chronic Pelvic Pain Syndrome; Erectile Dysfunction |
Xintian Pharmaceutical |
2019-03-19 | PHASE4 |
| NCT03855332 | COMPLETED | Small Vessel Cerebrovascular Disease |
University of Oxford |
2019-07-11 | PHASE2 |
| NCT03028298 | UNKNOWN | Subarachnoid Hemorrhage; Cerebral Vasospasm |
University of Mississippi Medical Center |
2016-12 | PHASE1 |
| NCT05558176 | UNKNOWN | Foetal Hypoxia |
Ladoke Akintola University of Technology Teaching Hospital, Ogbomoso |
2022-04-08 | PHASE4 |
| NCT02930811 | WITHDRAWN | Peripheral Arterial Occlusive Disease |
University Hospital, Angers |
PHASE3 | |
| NCT05439486 | UNKNOWN | Erectile Dysfunction |
Sohag University |
2022-01-29 | |
| NCT05369481 | UNKNOWN | Androgenic Alopecia |
Mohammed Abd El Mawgoud Amer |
2022-03-01 | |
| NCT05466695 | Not yet recruiting | Erectile Dysfunction and Neutrophil Lymphocyte Ratio |
Assiut University |
2022-08-01 | Early Phase 1 |
| NCT05275725 | Recruiting | Birth Asphyxia |
Pia Wintermark|Kawempe National Referral Hospital|Saint Francis Hospital|Walimu|McGill University Health Centre/Research Institute of the McGill University Health Centre |
2022-07-01 | Phase 1 |
| NCT03417492 | TERMINATED | Traumatic Brain Injury; Mild Traumatic Brain Injury; Post-Concussion Syndrome |
University of Pennsylvania |
2018-03-01 | PHASE1 |
| NCT06527729 | COMPLETED | Alopecia Areata |
Assiut University |
2021-07-01 | EARLY_PHASE1 |
| NCT05846906 | COMPLETED | Infertility, Female |
Beni-Suef University |
2021-10-01 | PHASE2; PHASE3 |
| NCT04325243 | COMPLETED | Fetal Distress |
Assiut University |
2020-09-01 | PHASE4 |
| NCT04283435 | UNKNOWN | IVF; Endometrial Receptivity |
Cairo University |
2021-09-01 | PHASE1 |
| NCT04169191 | UNKNOWN | Birth Asphyxia |
McGill University Health Centre/Research Institute of the McGill University Health Centre |
2019-09-19 | PHASE1 |
| NCT04948151 | UNKNOWN | Female Sexual Arousal Disorder |
Strategic Science & Technologies, LLC |
2021-06-28 | PHASE2 |
| NCT03406169 | UNKNOWN | Erectile Dysfunction; Prostate Cancer |
Brooke Army Medical Center |
2017-02-13 | PHASE3 |
| NCT03724838 | UNKNOWN | Preeclampsia |
Aswan University Hospital |
2018-12-01 | |
| NCT04052269 | SUSPENDED | Glaucoma |
Imperial College London |
2019-06-21 | PHASE3 |
| NCT03686813 | COMPLETED | Edema, Pulmonary; Immersion; Diving |
Duke University |
2019-07-15 | PHASE2 |
| NCT03356353 | UNKNOWN | End Stage Heart Failure |
University of Calgary |
2018-03-12 | PHASE3 |
| NCT04770155 | TERMINATED | Vascular Function; Racial Disparity |
University of Mississippi Medical Center |
2021-05-27 | EARLY_PHASE1 |
| NCT03633565 | UNKNOWN | Myopathy |
Assiut University |
2018-09 | PHASE4 |
| NCT02284737 | TERMINATED | Pulmonary Arterial Hypertension |
Nanjing First Hospital, Nanjing Medical University |
2014-11-28 | PHASE4 |
| NCT03012386 | COMPLETED | Insulin Resistance; Endothelial Dysfunction |
Vanderbilt University Medical Center |
2017-01 | PHASE1; PHASE2 |
| NCT04565925 | Recruiting | Spinal Cord Injuries|Urinary Incontinence |
The University of Texas Medical Branch Galveston |
2021-07-07 | Phase 2 |
| NCT04882826 | UNKNOWN | Bioequivalence |
Pharmtechnology LLC |
2021-05-10 | PHASE1 |
| NCT04489446 | COMPLETED | Covid19; SARS-COV2 Infection |
Universidad Nacional Andres Bello |
2020-08-19 | PHASE1; PHASE2 |
| NCT04391868 | WITHDRAWN | Healthy |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2021-01-30 | PHASE1 |
| NCT04211272 | COMPLETED | Healthy |
Actelion |
2020-01-14 | PHASE1 |
| NCT02335242 | COMPLETED | Lymphatic Malformations; Lymphatic Diseases |
Stanford University |
2015-05-23 | PHASE2 |
| NCT02060487 | TERMINATED | Pulmonary Arterial Hypertension |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2014-09-22 | PHASE4 |
| NCT02795351 | COMPLETED | Migraine With Aura |
Herlev Hospital |
2015-06 | EARLY_PHASE1 |
| NCT03185364 | UNKNOWN | COPD; Pulmonary Hypertension |
Chinese Academy of Medical Sciences, Fuwai Hospital |
2017-06-15 | |
| NCT00955929 | TERMINATED | Penile Cancer; Erectile Dysfunction; Radical Prostatectomy |
Memorial Sloan Kettering Cancer Center |
2009-08-06 | |
| NCT02946944 | UNKNOWN | Pulmonary Embolism; Intermediate-high Risk; Combination of Oral Anticoagulation Therapy and Sildenafil |
Meshalkin Research Institute of Pathology of Circulation |
2016-10 | PHASE1 |
| NCT01817751 | COMPLETED | Glioblastoma; Recurrent Adult Brain Neoplasm; Malignant Glioma; WHO Grade III Glioma |
Virginia Commonwealth University |
2013-04-11 | PHASE2 |
| NCT00906269 | UNKNOWN | Impotence; Prostatic Neoplasms |
Hartford Hospital |
2009-07 | PHASE4 |
| NCT03229512 | COMPLETED | Hand Foot Skin Reaction |
Northwestern University |
2017-04-11 | EARLY_PHASE1 |
| NCT02908490 | TERMINATED | Arthritis, Rheumatoid; Atherosclerosis |
Kimberly Liang |
2017-04-01 | PHASE2 |
| NCT02983461 | ACTIVE_NOT_RECRUITING | Urinary Incontinence |
The University of Texas Medical Branch, Galveston |
2017-03-10 | PHASE1 |
| NCT04058132 | TERMINATED | Traumatic Brain Injury |
Uniformed Services University of the Health Sciences |
2019-08-09 | PHASE2 |
| NCT04304313 | UNKNOWN | COVID-19 |
Tongji Hospital |
2020-02-09 | PHASE3 |
| NCT03696758 | COMPLETED | Infant,Premature |
University of Wisconsin, Madison |
2018-10-30 | PHASE2 |
| NCT04356716 | COMPLETED | Choroidal Ischemia; Vitelliform Macular Dystrophy; Age-related Macular Degeneration; Central Serous Retinopathy; Retinitis Pigmentosa |
Columbia University |
2014-11-11 | PHASE2 |
| NCT02891850 | COMPLETED | Pulmonary Arterial Hypertension |
Bayer |
2017-01-11 | PHASE4 |
| NCT03854175 | UNKNOWN | Infertility |
Cairo University |
2019-02 | |
| NCT04170790 | UNKNOWN | Diabetes Mellitus, Type 2; Erectile Dysfunction With Diabetes Mellitus; Drug Interaction |
Ain Shams University |
2019-12-01 | |
| NCT02890238 | UNKNOWN | Infertility |
Cairo University |
2016-08 | PHASE4 |
| NCT02951429 | COMPLETED | Idiopathic Pulmonary Fibrosis |
Hoffmann-La Roche |
2016-12-31 | PHASE2 |
| NCT04126252 | COMPLETED | Erectile Dysfunction |
International Islamic University, Islamabad |
2018-08-29 | |
| NCT04718233 | COMPLETED | Recurrent Pregnancy Loss |
Ain Shams University |
2018-09-05 | PHASE2 |
| NCT03154476 | COMPLETED | Cirrhosis; Congenital Heart Disease |
Mayo Clinic |
2017-07-05 | PHASE3 |
| NCT04100759 | COMPLETED | Erectile Dysfunction; Smoking; Pharmacokinetics; Pharmacodynamics |
Ain Shams University |
2019-06-11 | PHASE1; PHASE2 |
| NCT03598140 | TERMINATED | Vascular System Injuries; Concussion, Brain; Post-Concussion Syndrome |
University of Texas Southwestern Medical Center |
2018-07-25 | PHASE2 |
| NCT03763045 | UNKNOWN | Pulmonary Hypertension; Hemodialysis Complication |
Ain Shams University |
2018-12-02 | PHASE2; PHASE3 |
| NCT02466802 | COMPLETED | Solid Tumor |
Virginia Commonwealth University |
2015-07-01 | PHASE1 |
| NCT02812433 | COMPLETED | Neonatal Encephalopathy |
McGill University Health Centre/Research Institute of the McGill University Health Centre |
2016-07 | PHASE1 |
| NCT03259516 | TERMINATED | Myelodysplastic Syndromes |
St. Petersburg State Pavlov Medical University |
2017-05-25 | PHASE1; PHASE2 |
| NCT03462017 | COMPLETED | Microvascular Coronary Artery Disease |
Sanofi |
2018-03-07 | PHASE1 |
| NCT04481789 | COMPLETED | Healthy Adult Subjects |
Shionogi |
2018-10-17 | PHASE1 |
| NCT03143465 | UNKNOWN | Migraine With Aura |
Danish Headache Center |
2016-08 | |
| NCT01913847 | UNKNOWN | Pulmonary Hypertension; Systolic Dysfunction |
Hanmi Pharmaceutical Company Limited |
2013-09 | PHASE3 |
| NCT03460470 | UNKNOWN | Heart Failure; Pulmonary Hypertension |
Hartford Hospital |
2018-02-14 | PHASE3 |
| NCT03766594 | COMPLETED | Miscarriage, Recurrent |
Ain Shams University |
2018-01-01 | PHASE1 |
| NCT01720524 | COMPLETED | Pulmonary Hypertension, Familial Persistent, of the Newborn |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2013-08-05 | PHASE3 |
| NCT03710369 | COMPLETED | Altitude; Hypoxia; Sildenafil; Exercise |
University of British Columbia |
2015-11-01 | |
| NCT03364335 | COMPLETED | Obesity |
NuSirt Biopharma |
2018-01-08 | PHASE2 |
| NCT04179747 | COMPLETED | Erectile Dysfunction |
International Islamic University, Islamabad |
2018-01-18 | |
| NCT02277132 | TERMINATED | Fetal Growth Restriction |
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) |
2015-01 | PHASE2; PHASE3 |
| NCT03301233 | COMPLETED | Endometrial Thickness |
Ain Shams University |
2017-11-01 | |
| NCT02057458 | COMPLETED | Cystic Fibrosis |
Augusta University |
2014-04 | PHASE2 |
| NCT02442492 | TERMINATED | Intrauterine Growth Restriction (IUGR); Fetal Growth Restriction (FGR) |
University of British Columbia |
2017-01 | PHASE2; PHASE3 |
| NCT03510338 | COMPLETED | Erectile Dysfunction |
N4 Pharma UK Ltd. |
2018-05-08 | PHASE1 |
| NCT04994860 | COMPLETED | Pulmonary Arterial Hypertension |
Bial - Portela C S.A. |
2018-03-22 | PHASE1 |
| NCT03169582 | UNKNOWN | Erectile Dysfunction |
Eduardo Vargas-Baquero |
2016-04-01 | PHASE4 |
| NCT02435303 | TERMINATED | Hypertension, Pulmonary; Diseases of Mitral Valve |
Asan Medical Center |
2016-05 | PHASE2; PHASE3 |
| NCT01616381 | UNKNOWN | Heart Failure; Pulmonary Hypertension |
Helse Stavanger HF |
2013-03 | PHASE3 |
| NCT02378649 | COMPLETED | Pulmonary Hypertension; Mitral Valve Surgery |
Dr. Robert Klempfner Heart Rehabilitation Institute |
2015-03 | PHASE4 |
| NCT03230162 | UNKNOWN | Fetal Growth Abnormality; Fetal Growth Restriction |
Ain Shams University |
2017-06-01 | PHASE3 |
| NCT03755037 | COMPLETED | Female Infertility |
Nesreen Abdel Fattah Abdullah Shehata |
2017-01-31 | PHASE1 |
| NCT02798159 | COMPLETED | Erectile Dysfunction |
Vietstar Biomedical Research |
2016-05 | PHASE2; PHASE3 |
| NCT02626182 | COMPLETED | Cystic Fibrosis |
National Jewish Health |
2015-12 | PHASE1; PHASE2 |
| NCT02620995 | COMPLETED | Arterial Hypertension; Erectile Dysfunction |
National Institute of Cardiology, Laranjeiras, Brazil |
2014-10 | PHASE4 |
| NCT03153215 | COMPLETED | Intra-Uterine Growth Retardation |
Beni-Suef University |
2017-05-06 | |
| NCT02802345 | COMPLETED | Idiopathic Pulmonary Fibrosis |
Boehringer Ingelheim |
2016-06-30 | PHASE3 |
| NCT03262961 | UNKNOWN | Pre-Eclampsia; Mild |
Assiut University |
2016-09-15 | PHASE2; PHASE3 |
| NCT03475160 | COMPLETED | Recurrent Abortion |
Benha University |
2015-12-01 | |
| NCT03053739 | UNKNOWN | Associated Pulmonary Arterial Hypertension |
Post Graduate Institute of Medical Education and Research, Chandigarh |
2016-12 | PHASE4 |
| NCT02114775 | COMPLETED | Traumatic Brain Injury |
The University of Texas Medical Branch, Galveston |
2014-12-12 | PHASE1 |
| NCT01517854 | TERMINATED | Portopulmonary Hypertension |
University Health Network, Toronto |
2012-11-14 | PHASE2 |
| NCT02832570 | COMPLETED | Peripheral Arterial Occlusive Disease |
University Hospital, Angers |
2016-11-07 | PHASE3 |
| NCT03177824 | UNKNOWN | Fetal Growth Restriction |
Ain Shams University |
2017-03-30 | PHASE3 |
| NCT04283240 | COMPLETED | Pulmonary Embolism |
University of Aarhus |
2015-03-01 | EARLY_PHASE1 |
| NCT03236818 | UNKNOWN | Pulmonary Arterial Hypertension |
Amsterdam UMC, location VUmc |
2013-05 | PHASE4 |
| NCT01375699 | COMPLETED | Breast Cancer; Gastrointestinal Cancer; Genitourinary Cancer; Sarcoma; Gynecologic Cancer |
Virginia Commonwealth University |
2011-08-11 | PHASE1 |
| NCT03044561 | UNKNOWN | IVF Failure |
Ain Shams University |
2017-01-31 | PHASE4 |
| NCT03192709 | UNKNOWN | Infertility, Female |
Royan Institute |
2015-02 | PHASE1; PHASE2 |
| NCT02519153 | UNKNOWN | Ureteral Stone; Urolithiasis |
Mansoura University |
2014-07 | PHASE4 |
| NCT03431649 | COMPLETED | Pediatric Pulmonary Hypertension |
Dr. Soetomo General Hospital |
2017-04-01 | PHASE4 |
| NCT02782559 | WITHDRAWN | Preterm Preeclampsia |
The University of Texas Health Science Center, Houston |
2016-07 | PHASE2; PHASE3 |
| NCT02414204 | COMPLETED | Improve Endothelial Function and Decrease Vascular Stenosis |
University of Alabama at Birmingham |
2015-04 | |
| NCT02387450 | UNKNOWN | Peripheral Arterial Disease |
University Hospital, Angers |
2015-09 | PHASE2; PHASE3 |
| NCT02106871 | WITHDRAWN | Pancreatic Cancer; Cholangiocarcinoma |
The University of Texas Medical Branch, Galveston |
2014-04 | PHASE1 |
| NCT02590536 | COMPLETED | Fetal Growth Retardation |
Ain Shams University |
2015-10 | PHASE3 |
| NCT02304705 | TERMINATED | Heart Failure With Reactive Pulmonary Hypertension |
Maya Guglin |
2015-01 | PHASE4 |
| NCT02939495 | COMPLETED | Premature Ejaculation; Erectile Dysfunction |
Neutec Ar-Ge San ve Tic A.Ş |
2016-10 | PHASE4 |
| NCT02570282 | COMPLETED | Sexual Arousal Disorder |
Strategic Science & Technologies, LLC |
2015-09 | PHASE2 |
| NCT01132482 | COMPLETED | Cystic Fibrosis |
National Jewish Health |
2015-10 | PHASE2 |
| NCT02390960 | COMPLETED | Erectile Dysfunction |
Strategic Science & Technologies, LLC |
2015-03 | PHASE2 |
| NCT02975037 | COMPLETED | Healthy |
Seoul National University Hospital |
2017-02-06 | PHASE1 |
| NCT02678221 | UNKNOWN | Intrauterine Growth Restriction |
Assiut University |
2016-02 | PHASE2 |
| NCT02663830 | COMPLETED | Anovulatory |
Ain Shams University |
2016-01-10 | PHASE2 |
| NCT00223717 | COMPLETED | Hypertension |
Vanderbilt University |
2001-01 | PHASE1 |
| NCT00981747 | TERMINATED | Idiopathic Pulmonary Fibrosis; Pulmonary Fibrosis |
Alicia Gerke |
2009-09 | PHASE2; PHASE3 |
| NCT02546609 | COMPLETED | NAFLD |
NuSirt Biopharma |
2015-11-19 | PHASE2 |
| NCT01409993 | TERMINATED | Impaired Glucose Tolerance |
Vanderbilt University |
2011-08 | PHASE4 |
| NCT02345980 | COMPLETED | Quality of Life |
Mansoura University |
2014-03 | PHASE4 |
| NCT02244528 | COMPLETED | Neonates and Preterm Infants |
Seoul National University Hospital |
2014-10 | PHASE2 |
| NCT02337881 | UNKNOWN | Labor Preterm Requiring Hospitalization |
Al Hayat National Hospital |
2015-01 | PHASE1 |
| NCT02129725 | COMPLETED | Metabolic Syndrome |
Vanderbilt University Medical Center |
2014-04 | PHASE4 |
| NCT02628847 | TERMINATED | Stroke |
University of Utah |
2012-03 | PHASE1 |
| NCT02524184 | UNKNOWN | Obesity |
Xiang Guang-da |
2015-08 | PHASE4 |
| NCT03027674 | COMPLETED | Raynaud Phenomenon Due to Trauma; Raynaud Disease; System; Sclerosis; Lupus Erythematosus, Systemic; Dermatomyositis; Ultrasound Therapy; Complications |
Pontificia Universidad Catolica de Chile |
2016-08 | EARLY_PHASE1 |
| NCT01996852 | TERMINATED | Prostate Cancer; Erectile Dysfunction Following Radical Prostatectomy; Erectile Dysfunction Following Simple Prostatectomy; Erectile Dysfunction |
Case Comprehensive Cancer Center |
2013-07 | |
| NCT01670136 | COMPLETED | Persistent Pulmonary Hypertension of the Newborn |
University of North Carolina, Chapel Hill |
2013-02 | PHASE1 |
| NCT00862043 | COMPLETED | Pulmonary Hypertension; Valvular Heart Disease |
Hospital General Universitario Gregorio Marañon |
2009-04 | PHASE4 |
| NCT02372487 | UNKNOWN | Pregnancy Complication |
Al Hayat National Hospital |
2015-03 | |
| NCT01642407 | COMPLETED | Pulmonary Arterial Hypertension; Hypertension, Pulmonary |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2012-08-24 | PHASE4 |
| NCT02845388 | COMPLETED | Infertility |
Omar Ahmed El Sayed Saad |
2015-09 | PHASE2 |
| NCT02850718 | COMPLETED | Erectile Dysfunction |
iX Biopharma Ltd. |
2016-03 | PHASE3 |
| NCT02362399 | COMPLETED | Pregnancy Complication |
Al Hayat National Hospital |
2015-03 | |
| NCT01950923 | COMPLETED | Kidney Tumor |
Wake Forest University Health Sciences |
2013-09 | PHASE1 |
| NCT02710981 | COMPLETED | Anovulation |
Assiut University |
2015-06 | |
| NCT01762475 | COMPLETED | Traumatic Brain Injury; Post-concussive Syndrome |
Uniformed Services University of the Health Sciences |
2013-01 | PHASE2 |
| NCT00815646 | COMPLETED | Immersion Pulmonary Edema (IPE); Swimming Induced Pulmonary Edema (SIPE) |
Duke University |
2008-01 | EARLY_PHASE1 |
| NCT02766725 | COMPLETED | Infertility |
Assiut University |
2015-01 | PHASE2; PHASE3 |
| NCT01954524 | TERMINATED | Cirrhosis |
University of Maryland, Baltimore |
2014-05 | PHASE1 |
| NCT02595541 | COMPLETED | Pulmonary Hypertension |
Assiut University |
2015-06 | PHASE1; PHASE2 |
| NCT01661595 | COMPLETED | Fatigue |
The University of Texas Medical Branch, Galveston |
2012-11 | |
| NCT02050360 | COMPLETED | Raynaud's Phenomenon |
University Hospital, Grenoble |
2013-11 | PHASE2; PHASE3 |
| NCT02364882 | COMPLETED | Female Sexual Health |
Strategic Science & Technologies, LLC |
2015-01 | PHASE1 |
| NCT04391478 | COMPLETED | Persistent Pulmonary Hypertension |
Rania Ali El-Farrash |
2015-01 | PHASE1 |
| NCT01812434 | WITHDRAWN | Cardiac Allograft Vasculopathy |
University of Minnesota |
2010-10 | |
| NCT01889966 | COMPLETED | Pulmonary Hypertension Associated With Connective Tissue Disease |
Kerckhoff Heart Center |
2013-04 | PHASE4 |
| NCT02136329 | COMPLETED | Acute Kidney Injury |
University of Leicester |
2013-06 | PHASE1 |
| NCT01637675 | UNKNOWN | Pulmonary Hypertension; Pulmonary Arterial Hypertension; Cardiovascular Diseases; Lung Diseases; Tanshinone IIA Sulfonate |
The First Affiliated Hospital of Guangzhou Medical University |
2013-05 | PHASE2; PHASE3 |
| NCT01815502 | COMPLETED | Single Ventricle Heart Disease After Fontan Surgery |
Medical University of South Carolina |
2013-02 | PHASE4 |
| NCT01558466 | UNKNOWN | Persistent Fetal Circulation Syndrome |
Hamad Medical Corporation |
2011-11 | PHASE3 |
| NCT01853540 | COMPLETED | Nontuberculous Mycobacterial Infection |
National Institute of Allergy and Infectious Diseases (NIAID) |
2013-01 | PHASE1; PHASE2 |
| NCT01726049 | COMPLETED | Heart Failure, Diastolic; Pulmonary Hypertension |
University Medical Center Groningen |
2011-10 | PHASE3 |
| NCT01044693 | COMPLETED | Hypertension; Pure Autonomic Failure; Multiple System Atrophy |
Vanderbilt University |
2010-01 | |
| NCT01830790 | TERMINATED | Age-related Macular Degeneration |
Duke University |
2013-03 | PHASE2 |
| NCT00142506 | COMPLETED | Prostate Cancer; Erectile Dysfunction |
Memorial Sloan Kettering Cancer Center |
2005-02 | PHASE3 |
| NCT01572363 | COMPLETED | Congenital Heart Disease |
Universitaire Ziekenhuizen KU Leuven |
2012-04 | |
| NCT02028598 | COMPLETED | Healthy |
CTC Bio, Inc. |
2014-01 | PHASE1 |
| NCT03733470 | COMPLETED | Emphysema |
Eric A. Hoffman |
2011-06-29 | PHASE4 |
| NCT01168908 | TERMINATED | Duchenne Muscular Dystrophy; Becker Muscular Dystrophy |
Hugo W. Moser Research Institute at Kennedy Krieger, Inc. |
2010-09 | PHASE2 |
| NCT01548950 | COMPLETED | Congenital Heart Disease; Pulmonary Arterial Hypertension |
University of Sao Paulo General Hospital |
2011-09 | |
| NCT01800292 | COMPLETED | Hypertension, Pulmonary Artery; Ventricular Dysfunction, Left |
University of Arizona |
2013-02 | PHASE4 |
| NCT00303459 | COMPLETED | Pulmonary Arterial Hypertension |
Actelion |
2006-05 | PHASE4 |
| NCT01936350 | COMPLETED | Heart Failure |
Hospital Ana Nery |
2013-09 | PHASE2; PHASE3 |
| NCT02028429 | UNKNOWN | Hepatic Encephalopathy. |
Post Graduate Institute of Medical Education and Research, Chandigarh |
2012-07 | PHASE1; PHASE2 |
| NCT01986673 | COMPLETED | Healthy |
Strategic Science & Technologies, LLC |
2013-10 | PHASE1 |
| NCT01409031 | TERMINATED | Persistent Pulmonary Hypertension; Respiratory Failure |
University of Colorado, Denver |
2011-07 | PHASE2 |
| NCT00323297 | COMPLETED | Pulmonary Arterial Hypertension |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2006-09 | PHASE4 |
| NCT01295736 | COMPLETED | Systemic Scleroderma |
University Hospital, Lille |
2010-11 | PHASE3 |
| NCT01334554 | COMPLETED | Metabolic Syndrome; Obesity |
Vanderbilt University Medical Center |
2011-04 | PHASE1; PHASE2 |
| NCT01059994 | COMPLETED | Fatigue; Aging |
The University of Texas Medical Branch, Galveston |
2010-01 | |
| NCT00133679 | TERMINATED | Hernia, Diaphragmatic; Hypertension, Pulmonary; Hypoplasia, Pulmonary |
University of California, San Francisco |
2006-02 | PHASE4 |
| NCT01449253 | UNKNOWN | Pulmonary Hypertension Secondary to Lung Disease and/or Hypoxia |
All India Institute of Medical Sciences |
2011-08 | PHASE4 |
| NCT01481350 | COMPLETED | Pulmonary Hypertension |
University of Turin, Italy |
2012-02 | PHASE2 |
| NCT01359670 | COMPLETED | Duchenne Muscular Dystrophy |
Cedars-Sinai Medical Center |
2011-05 | EARLY_PHASE1 |
| NCT01432665 | COMPLETED | Hypoactive Sexual Desire Disorder |
Emotional Brain NY Inc. |
2011-09 | PHASE2 |
| NCT01350154 | COMPLETED | Becker Muscular Dystrophy |
Rigshospitalet, Denmark |
2011-11 | PHASE2 |
| NCT01360671 | WITHDRAWN | Persistent Pulmonary Hypertension of the Newborn |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2012-03 | PHASE2 |
| NCT01290484 | COMPLETED | Lymphangioma |
Stanford University |
2010-12 | PHASE1; PHASE2 |
| NCT01499498 | COMPLETED | Hepatitis C |
Imperial College London |
2012-12 | PHASE1 |
| NCT01580501 | COMPLETED | Duchenne Muscular Dystrophy |
Cedars-Sinai Medical Center |
2012-03 | PHASE1 |
| NCT01441934 | UNKNOWN | Pulmonary Hypertension; COPD |
Italian Association of Hospital Pneumologists |
2010-10 | PHASE3 |
| NCT01347008 | COMPLETED | Scleroderma, Systemic; Scleroderma, Diffuse; Scleroderma, Limited; Raynaud Phenomenon |
Federal University of São Paulo |
2011-04 | PHASE3 |
| NCT01601470 | COMPLETED | Mild to Moderate Hypertension |
Novartis Pharmaceuticals |
2012-09 | PHASE2 |
| NCT00159874 | COMPLETED | Pulmonary Arterial Hypertension |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2004-01 | PHASE3 |
| NCT01091870 | WITHDRAWN | Subarachnoid Hemorrhage; Cerebral Vasospasm; Rupture of Intracranial Aneurysm |
Hospital de Clinicas de Porto Alegre |
2010-03 | PHASE2 |
| NCT00730067 | WITHDRAWN | COPD; Pulmonary Hypertension |
University of Aarhus |
2012-06 | PHASE4 |
| NCT01169519 | COMPLETED | Heart Disease |
Duke University |
2011-04 | PHASE1 |
| NCT01091012 | UNKNOWN | Pulmonary Hypertension |
Hospital Universitari Vall d'Hebron Research Institute |
2011-09 | PHASE3 |
| NCT01194232 | WITHDRAWN | Cystic Fibrosis With Mild to Moderate Lung Disease; CMRI of Lung Perfusion; Lung Perfusion; Lung Vascularization |
Children's Hospital Medical Center, Cincinnati |
2012-08 | PHASE1; PHASE2 |
| NCT01054001 | UNKNOWN | Prostate Cancer |
Seoul National University Bundang Hospital |
2010-06 | |
| NCT01382368 | UNKNOWN | Chronic Obstructive Pulmonary Disease; Idiopathic Pulmonary Fibrosis |
Rabin Medical Center |
2011-09 | PHASE4 |
| NCT00940901 | COMPLETED | Sickle Cell Disease; Priapism |
Johns Hopkins University |
2008-06 | PHASE2 |
| NCT01392469 | COMPLETED | Pulmonary Arterial Hypertension |
Novartis Pharmaceuticals |
2011-04-20 | PHASE3 |
| NCT00478335 | COMPLETED | Nephrogenic Diabetes Insipidus |
University of Colorado, Denver |
2007-05 | |
| NCT01737203 | COMPLETED | Healthy |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2012-08 | PHASE1 |
| NCT00763867 | COMPLETED | Heart Failure |
Duke University |
2008-09 | PHASE3 |
| NCT01315262 | UNKNOWN | Erectile Dysfunction |
Università Vita-Salute San Raffaele |
2011-01 | PHASE3 |
| NCT01757782 | COMPLETED | Meconium Aspiration Syndrome; Persistent Pulmonary Hypertension of Newborn |
Sir Takhtasinhji General Hospital |
2011-12 | PHASE4 |
| NCT01656798 | COMPLETED | Healthy |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2012-08 | PHASE1 |
| NCT00659529 | COMPLETED | Cystic Fibrosis |
National Jewish Health |
2008-08 | PHASE1; PHASE2 |
| NCT01392638 | COMPLETED | Hypertension |
University of Campinas, Brazil |
2010-07 | |
| NCT01948518 | COMPLETED | Diffuse Parenchymal Lung Disease; Pulmonary Hypertension |
The Cleveland Clinic |
2009-06 | |
| NCT01364701 | UNKNOWN | Erectile Dysfunction |
Rambam Health Care Campus |
2011-06 | PHASE4 |
| NCT01179334 | COMPLETED | Pulmonary Hypertension |
Bayer |
2010-08 | PHASE2 |
| NCT01352507 | COMPLETED | Erectile Dysfunction |
Eli Lilly and Company |
2011-06 | PHASE4 |
| NCT00964782 | COMPLETED | Fontan Circulation |
Milton S. Hershey Medical Center |
2009-08 | PHASE4 |
| NCT00586794 | TERMINATED | Pulmonary Arterial Hypertension (PAH) |
Competence Network for Congenital Heart Defects |
2007-12 | PHASE3 |
| NCT00544076 | TERMINATED | Prostate Cancer; Male Erectile Disorder; Stage I Prostate Cancer; Stage II Prostate Cancer |
City of Hope Medical Center |
2006-01 | PHASE3 |
| NCT01219023 | COMPLETED | Hand Foot Syndrome; Palmar Plantar Erythrodysesthesia |
Duke University |
2010-06 | PHASE1 |
| NCT01419392 | UNKNOWN | Recurrent Miscarriage |
Ain Shams University |
2011-09 | PHASE4 |
| NCT01046838 | COMPLETED | Heart Failure, Diastolic |
Jacob E Mueller |
2009-12 | PHASE4 |
| NCT01321489 | UNKNOWN | Erectile Dysfunction |
Laboratório Teuto Brasileiro S/A |
2011-09 | PHASE3 |
| NCT01409122 | COMPLETED | Pulmonary Hypertension; Pulmonary Arterial Hypertension |
Aires Pharmaceuticals, Inc. |
2011-07 | PHASE1 |
| NCT01514903 | COMPLETED | Erectile Dysfunction |
Hanmi Pharmaceutical Company Limited |
2011-12 | PHASE1 |
| NCT01373749 | UNKNOWN | Persistent Pulmonary Hypertension of Newborn |
Third Military Medical University |
2011-03 | |
| NCT01391104 | COMPLETED | Pulmonary Arterial Hypertension |
Laval University |
2009-04 | |
| NCT01069861 | TERMINATED | PPHN; Persistent Pulmonary Hypertension of the Newborn; Hypoxic Respiratory Failure |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2010-12 | PHASE2 |
| NCT01769638 | COMPLETED | Healthy |
Seoul Pharma Co., Ltd. |
2011-09 | PHASE1 |
| NCT01060020 | COMPLETED | Aortic Stenosis |
Washington University School of Medicine |
2010-01 | PHASE4 |
| NCT00742014 | TERMINATED | Hypertension |
The Hospital for Sick Children |
2008-08 | PHASE3 |
| NCT00710099 | COMPLETED | Healthy |
University Hospital, Grenoble |
2008-07 | |
| NCT01122264 | COMPLETED | Erectile Dysfunction |
Eli Lilly and Company |
2010-05 | PHASE4 |
| NCT00123162 | COMPLETED | Dysmenorrhea |
Milton S. Hershey Medical Center |
2007-05 | PHASE1; PHASE2 |
| NCT01254383 | COMPLETED | Erectile Dysfunction |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2010-12 | PHASE1 |
| NCT01055405 | COMPLETED | COPD; Pulmonary Hypertension |
Hospital Clinic of Barcelona |
2008-08 | PHASE4 |
| NCT00796666 | TERMINATED | Pulmonary Arterial Hypertension; Pulmonary Hypertension |
Pfizer |
2009-05 | PHASE3 |
| NCT01247805 | COMPLETED | Pulmonary Arterial Hypertention |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2011-01 | PHASE1 |
| NCT00617305 | COMPLETED | Pulmonary Arterial Hypertension |
Gilead Sciences |
2008-04 | PHASE4 |
| NCT01254396 | COMPLETED | Erectile Dysfunction |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2010-12 | PHASE1 |
| NCT00498680 | UNKNOWN | Impotence |
Rambam Health Care Campus |
2007-03 | PHASE4 |
| NCT00796510 | TERMINATED | Pulmonary Arterial Hypertension; Pulmonary Hypertension |
Pfizer |
2010-07 | PHASE3 |
| NCT01244620 | TERMINATED | Pulmonary Arterial Hypertension |
Pfizer |
2010-11 | PHASE1 |
| NCT00598585 | COMPLETED | Chronic Fatigue Syndrome |
Charles Drew University of Medicine and Science |
2002-07 | PHASE4 |
| NCT00793338 | WITHDRAWN | Heart Failure |
University of New Mexico |
2008-11 | PHASE4 |
| NCT00818701 | TERMINATED | Congestive Heart Failure; Renal Dysfunction |
Mayo Clinic |
2009-02 | PHASE1 |
| NCT00853112 | TERMINATED | Hypertension, Pulmonary |
Pfizer |
2009-04 | PHASE2 |
| NCT00431418 | COMPLETED | Lung Diseases |
Mercy Hospital for Women, Australia |
2007-01 | PHASE3 |
| NCT00872170 | COMPLETED | Thalassemia; Hypertension, Pulmonary |
Carelon Research |
2009-03 | PHASE2; PHASE3 |
| NCT01107782 | UNKNOWN | Fetal Growth Retardation |
Tehran University of Medical Sciences |
2008-06 | PHASE2; PHASE3 |
| NCT00430716 | TERMINATED | Pulmonary Arterial Hypertension |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2008-04-08 | PHASE4 |
| NCT00512707 | COMPLETED | Erectile Dysfunction; Testosterone Deficiency; Diabetes |
Boston University |
2006-11 | PHASE4 |
| NCT00433329 | COMPLETED | Pulmonary Arterial Hypertension |
Actelion |
2007-03 | PHASE4 |
| NCT00904748 | COMPLETED | Erectile Dysfunction |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2010-01 | PHASE1 |
| NCT00808912 | COMPLETED | Pulmonary Hypertension; Pulmonary Artery Pressure; Exercise Performance; Air Pollution |
Marywood University |
2008-12 | |
| NCT00454714 | WITHDRAWN | Coronary Vasospasm |
Udo Sechtem |
2007-03-01 | PHASE3 |
| NCT01185925 | COMPLETED | Heart Failure |
University of Milan |
2008-04 | PHASE2 |
| NCT00781508 | COMPLETED | Heart Failure; Left Ventricular Dysfunction |
MetroHealth Medical Center |
2006-12 | PHASE4 |
| NCT00734604 | COMPLETED | Erectile Dysfunction |
Eli Lilly and Company |
2008-08 | PHASE3 |
| NCT00492531 | TERMINATED | Sickle Cell Disease; Pulmonary Hypertension |
National Heart, Lung, and Blood Institute (NHLBI) |
2007-06 | PHASE2 |
| NCT00914277 | COMPLETED | Erectile Dysfunction |
Sanofi |
2009-05 | PHASE2 |
| NCT01156636 | COMPLETED | Pulmonary Hypertension; Diastolic Heart Failure |
University of Milan |
2006-01 | PHASE2; PHASE3 |
| NCT00692237 | COMPLETED | Diabetes Mellitus, Type 2; Endothelial Dysfunction |
University of Roma La Sapienza |
2008-01 | PHASE4 |
| NCT01668446 | COMPLETED | Endometrial Preparation; Frozen Embryo Transfer |
farzaneh hojjat |
2009-09 | PHASE4 |
| NCT00950404 | COMPLETED | Healthy Volunteers |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2009-08 | PHASE1 |
| NCT00937144 | WITHDRAWN | Sickle Cell Anemia |
The Baruch Padeh Medical Center, Poriya |
2009-09 | PHASE4 |
| NCT00680654 | COMPLETED | Hypertension, Pulmonary |
Bayer |
2008-10 | PHASE1 |
| NCT00625079 | WITHDRAWN | Pulmonary Arterial Hypertension; Idiopathic Pulmonary Fibrosis; Interstitial Lung Disease; Pulmonary Hypertension |
University of California, Los Angeles |
2007-02 | PHASE4 |
| NCT00517933 | COMPLETED | Pulmonary Fibrosis; Hypertension, Pulmonary |
Duke University |
2007-08 | PHASE3 |
| NCT00334490 | COMPLETED | Pulmonary Hypertension |
Unity Health Toronto |
2005-03 | PHASE2 |
| NCT00507819 | COMPLETED | Hypoplastic Left Heart Syndrome; Tricuspid Atresia |
Children's Hospital of Philadelphia |
2007-12 | PHASE2 |
| NCT00902512 | COMPLETED | Healthy Males |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2009-04 | PHASE4 |
| NCT00327080 | TERMINATED | HIV |
National Heart, Lung, and Blood Institute (NHLBI) |
2006-05-12 | PHASE1 |
| NCT00752115 | COMPLETED | Non-small Cell Lung Cancer |
Hamamatsu University |
2007-02 | PHASE2; PHASE3 |
| NCT00871065 | WITHDRAWN | Cerebral Vasospasm; Subarachnoid Hemorrhage |
University of Nebraska |
2008-07 | PHASE2 |
| NCT00454207 | COMPLETED | Pulmonary Hypertension |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2007-04 | PHASE3 |
| NCT00772135 | UNKNOWN | Congenital Heart Disease |
Oslo University Hospital |
2008-09 | |
| NCT00685945 | COMPLETED | Obesity |
Vanderbilt University |
2007-12 | |
| NCT02162979 | TERMINATED | Parkinson's Disease |
Loma Linda University |
2002-02 | PHASE2 |
| NCT00800592 | COMPLETED | Hypertension, Pulmonary |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2008-10 | PHASE1 |
| NCT00104637 | COMPLETED | Pulmonary Disease, Chronic Obstructive; Emphysema |
Kawut, Steven, MD |
2005-02 | PHASE2 |
| NCT00795938 | COMPLETED | Erectile Dysfunction |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2008-10 | PHASE1 |
| NCT00491803 | COMPLETED | Chronic Obstructive Pulmonary Disease; Pulmonary Hypertension |
Hospital Clinic of Barcelona |
2007-06 | PHASE4 |
| NCT00359736 | COMPLETED | Alveolitis, Fibrosing; Fibrosis, Pulmonary; Hypertension, Pulmonary |
VA Office of Research and Development |
2006-07 | PHASE2 |
| NCT00866463 | COMPLETED | Erectile Dysfunction |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2008-10 | PHASE1 |
| NCT00814736 | COMPLETED | Prostatic Hyperplasia; Urinary Bladder, Overactive; Erectile Dysfunction |
Pfizer |
2008-08 | PHASE1 |
| NCT00507286 | UNKNOWN | Erectile Dysfunction |
Keogh Institute for Medical Research |
2007-05 | |
| NCT00159913 | COMPLETED | Pulmonary Arterial Hypertension, Children |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2003-08 | PHASE3 |
| NCT00587379 | WITHDRAWN | Endothelial Dysfunction |
Mayo Clinic |
2004-06 | |
| NCT00599235 | COMPLETED | Hypertension |
University of Edinburgh |
2007-03 | |
| NCT00468650 | COMPLETED | Erectile Dysfunction |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2007-06 | PHASE4 |
| NCT00862888 | COMPLETED | Erectile Dysfunction |
Pfizer |
2007-07 | PHASE2 |
| NCT00303004 | COMPLETED | Eisenmenger Syndrome |
Rigshospitalet, Denmark |
2006-03 | PHASE3 |
| NCT00302211 | TERMINATED | Pulmonary Hypertension |
Actelion |
2006-02-01 | PHASE3 |
| NCT00199563 | COMPLETED | Impotence |
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's |
2004-08 | PHASE4 |
| NCT00511498 | COMPLETED | Prostate Cancer |
Johns Hopkins University |
2006-03 | |
| NCT00301262 | COMPLETED | Impotence |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2005-11 | PHASE4 |
| NCT00455715 | COMPLETED | Schizophrenia |
Massachusetts General Hospital |
2006-02 | PHASE4 |
| NCT00165295 | COMPLETED | Waldenstrom's Macroglobulinemia |
Dana-Farber Cancer Institute |
2005-09 | PHASE2 |
| NCT00056433 | COMPLETED | Sickle Cell Anemia |
National Institutes of Health Clinical Center (CC) |
2003-03-10 | PHASE1 |
| NCT00057759 | COMPLETED | Prostate Cancer; Psychosocial Effects of Cancer and Its Treatment; Radiation Toxicity; Sexual Dysfunction; Sexuality and Reproductive Issues |
Radiation Therapy Oncology Group |
2003-01 | |
| NCT00145483 | COMPLETED | Meniere's Disease |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2002-06-18 | PHASE4 |
| NCT00145938 | TERMINATED | Pulmonary Hypertension |
University of Chicago |
2003-09 | PHASE2 |
| NCT00080808 | COMPLETED | Prostate Cancer |
M.D. Anderson Cancer Center |
2001-08 | PHASE2 |
| NCT00194909 | COMPLETED | Diabetic Neuropathy |
Weill Medical College of Cornell University |
2004-08 | PHASE4 |
| NCT00655590 | COMPLETED | Erectile Dysfunction |
Bayer |
2005-01 | PHASE4 |
| NCT00143260 | COMPLETED | Impotence |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2005-08 | PHASE4 |
| NCT00624273 | COMPLETED | Active Digital Ulcers |
Charite University, Berlin, Germany |
2004-02 | PHASE2 |
| NCT01616485 | COMPLETED | Erectile Dysfunction |
VIVUS LLC |
2004-03 | PHASE1 |
| NCT01941732 | COMPLETED | Parkinsons Disease; Erectile Dysfunction |
Bispebjerg Hospital |
2003-11 | PHASE4 |
| NCT00159848 | COMPLETED | Impotence |
Pfizer |
2003-09 | PHASE4 |
| NCT00297544 | UNKNOWN | Impotence |
Rambam Health Care Campus |
2005-10 | |
| NCT00194597 | TERMINATED | Prostatitis |
University of Washington |
2004-07 | PHASE4 |
| NCT00343200 | COMPLETED | Impotence |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2006-07 | PHASE4 |
| NCT00640458 | COMPLETED | Female Sexual Arousal Disorder |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2004-04 | PHASE2 |
| NCT00461565 | COMPLETED | Safety |
Bayer |
2005-02 | PHASE4 |
| NCT00644956 | COMPLETED | Erectile Dysfunction |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2003-06 | PHASE4 |
| NCT00159861 | COMPLETED | Pulmonary Hypertension |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2003-07 | PHASE3 |
| NCT00159900 | COMPLETED | Erectile Dysfunction |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2005-05 | PHASE4 |
| NCT00317421 | COMPLETED | Hypertension |
University of Edinburgh |
2004-03 | PHASE2 |
| NCT00420901 | COMPLETED | Diabetes |
IRCCS San Raffaele |
1999-01 | PHASE3 |
| NCT00645034 | COMPLETED | Benign Prostatic Hyperplasia |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2002-11 | PHASE2 |
| NCT00273416 | COMPLETED | Impotence |
Pfizer |
2006-01 | PHASE2 |
| NCT00645268 | COMPLETED | Erectile Dysfunction; Diabetes Mellitus, Type 2 |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2002-12 | PHASE4 |
| NCT00245596 | COMPLETED | Impotence |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2005-10 | PHASE4 |
| NCT00150358 | COMPLETED | Impotence; Hypertension |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2005-03 | PHASE4 |
| NCT00159887 | COMPLETED | Pulmonary Hypertension |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2002-12 | PHASE3 |
| NCT00452582 | TERMINATED | Ischemic Stroke |
Henry Ford Health System |
2005-04 | PHASE1 |
| NCT00151463 | COMPLETED | Impotence |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2005-01 | PHASE4 |
| NCT00746967 | COMPLETED | Sexual Dysfunctions, Psychological; Sexual Arousal Disorder |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2003-01 | PHASE2 |
| NCT00463957 | UNKNOWN | Erectile Dysfunction |
University of Cambridge |
2006-08 | |
| NCT00644631 | COMPLETED | Erectile Dysfunction |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2003-06 | PHASE4 |
| NCT00407446 | COMPLETED | Heart Failure |
University of Milan |
2004-01 | PHASE3 |
| NCT00352482 | COMPLETED | Pulmonary Fibrosis; Hypertension, Pulmonary |
National Heart, Lung, and Blood Institute (NHLBI) |
2004-11 | PHASE2 |
| NCT00155714 | WITHDRAWN | Primary and Secondary Pulmonary Hypertension |
National Taiwan University Hospital |
2002-11 | |
| NCT00527995 | COMPLETED | Type 2 Diabetes Mellitus; Endothelial Dysfunction |
Ruhr University of Bochum |
2001-08 | PHASE3 |
| NCT00249730 | COMPLETED | Impotence |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2005-10 | PHASE4 |
| NCT00333281 | COMPLETED | Erectile Dysfunction |
Eli Lilly and Company |
2005-06 | PHASE4 |
| NCT00479908 | COMPLETED | Angina Pectoris |
University of Edinburgh |
2004-01 | PHASE4 |
| NCT00644605 | COMPLETED | Hypertension, Pulmonary |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2002-10 | PHASE3 |
| NCT00175981 | COMPLETED | Healthy |
Heidelberg University |
2003-02 | PHASE1 |
| NCT00309790 | COMPLETED | Congestive Heart Failure |
Massachusetts General Hospital |
2003-05 | PHASE3 |
| NCT00648596 | COMPLETED | Erectile Dysfunction |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2003-05 | PHASE4 |
| NCT00251784 | COMPLETED | Blindness |
University of Cambridge |
2002-02 | PHASE4 |
| NCT00654017 | COMPLETED | Erectile Disfunction; Hemodialysis |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2002-10 | PHASE4 |
| NCT00245258 | COMPLETED | Impotence |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2005-11 | PHASE4 |
| NCT01153204 | COMPLETED | Erectile Dysfunction |
Federal University of São Paulo |
PHASE4 | |
| NCT00159809 | COMPLETED | Impotence; Depression |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2004-03 | PHASE4 |
| NCT00547287 | COMPLETED | Impotence |
Eli Lilly and Company |
2002-11 | PHASE3 |
| NCT00375297 | COMPLETED | Sexual Dysfunction; Depression |
University of New Mexico |
2001-01 | PHASE4 |
| NCT00347867 | UNKNOWN | IUGR |
Rambam Health Care Campus |
2006-07 | PHASE4 |
| NCT00313898 | UNKNOWN | Erectile Dysfunction |
Rambam Health Care Campus |
2005-09 | PHASE4 |
| NCT00141310 | TERMINATED | Pre-eclampsia |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2004-09 | PHASE2 |
| NCT00654082 | COMPLETED | Spinal Cord Injury; Erectile Dysfunction; Spinal Cord Trauma; Injuries, Spinal Cord; Impotence |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2002-09 | PHASE4 |
| NCT00627965 | COMPLETED | High Altitude Pulmonary Edema; Acute Mountain Sickness |
Altitude Physiology Expeditions |
2003-03 | PHASE4 |
| NCT00147628 | COMPLETED | Impotence |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2005-11 | PHASE4 |
| NCT00547352 | COMPLETED | Impotence |
Eli Lilly and Company |
2004-06 | PHASE4 |
| NCT00780728 | WITHDRAWN | Hypertension, Pulmonary |
University Health Network, Toronto |
PHASE3 | |
| NCT00309816 | COMPLETED | Congestive Heart Failure |
Massachusetts General Hospital |
2001-12 | PHASE3 |
| NCT00483626 | UNKNOWN | Pulmonary Arterial Hypertension |
University of Chile |
2003-08 | PHASE4 |
| NCT00547092 | COMPLETED | Impotence |
Eli Lilly and Company |
2003-10 | PHASE4 |
| NCT00137072 | COMPLETED | Impotence |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2005-04 | PHASE4 |
| NCT00975494 | COMPLETED | Heart Failure |
University of Milan |
2005-04 | PHASE3 |
| NCT00350441 | UNKNOWN | Cardiopulmonary Bypass |
NHS Greater Glasgow Yorkhill Division |
2006-06 | PHASE4 |
| NCT00143221 | COMPLETED | Impotence |
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
2004-03 | PHASE4 |
(data from https://clinicaltrials.gov, updated on 2026-05-11)
Check the
Sildenafil
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Compliance for Clinical Use
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
Jump to
Note: Technical data last updated: Sep 1, 2026.