CAS No. 50-67-9
Batch:
Purity:99.56
Chemical Structure
Check the
Serotonin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 3-(2-aminoethyl)-1H-indol-5-ol | |
|---|---|---|
| CAS Number | 50-67-9 | |
| Molecular Formula |
C10H12N2O |
|
| Molecular Weight (MW) | 176.22 | |
| InChIKey | QZAYGJVTTNCVMB-UHFFFAOYSA-N |
Serotonin is an endogenous monoamine neurotransmitter that acts as a broad-spectrum agonist of 5-hydroxytryptamine (5-HT) receptors and an inhibitor of catechol O-methyltransferase (COMT). By engaging multiple G-protein-coupled and ligand-gated 5-HT receptor subtypes, serotonin activates distinct downstream intracellular signaling cascades, regulating critical physiological processes including central neurotransmission, vascular tone, gastrointestinal motility, and mood regulation. [1]
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
43 mg/mL
(244.01 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
43 mg/mL
(244.01 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 2 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.