Molecular Weight: 457.68 g/mol
Chemical Structure
Check the
AZD6244 (Selumetinib)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
91 mg/mL
(198.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
92 mg/mL
(201.01 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
92 mg/mL
(201.01 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
92 mg/mL
(201.01 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
91 mg/mL
(198.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
| IUPAC Name | 6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide | |
|---|---|---|
| CAS Number | 606143-52-6 | |
| Molecular Formula |
C17H15BrClFN4O3 |
|
| Molecular Weight (MW) | 457.68 | |
| SMILES | CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO | |
| InChIKey | CYOHGALHFOKKQC-UHFFFAOYSA-N |
- AZD6244 (Selumetinib) Mechanism of Action: MEK1/2 Inhibition in Schwann Cell Research
- AZD6244 (Selumetinib) Clinical Trials
- AZD6244 (Selumetinib): Selectivity & Specificity
- AZD6244 (Selumetinib) Working Concentration | Cell Culture | Treatment
- AZD6244 (Selumetinib) Solubility in DMSO
- AZD6244 (Selumetinib) Stock Solution
- AZD6244 (Selumetinib) Storage
- AZD6244 (Selumetinib) Stability
- AZD6244 (Selumetinib) Combination Database
- AZD6244 (Selumetinib) SMILES
- AZD6244 (Selumetinib) CAS Number
- AZD6244 (Selumetinib) Chemical Structure (2D and 3D)
- AZD6244 (Selumetinib) IC50 for Cell-based and Cell-free Assays
- AZD6244 (Selumetinib) Sigma (sml3800)? Try a better option.
- AZD6244 (Selumetinib) MedChemExpress (HY-50706)? Try a better option.
- AZD6244 (Selumetinib) Cayman (11599)? Try a better option.
- AZD6244 (Selumetinib) APExBIO (A8207)? Try a better option.
- AZD6244 (Selumetinib) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.