AZD6244 (Selumetinib): Mechanism of Action

AZD6244 (Selumetinib) MOA:Targeting MEK1/2/MAPK Pathway for Neurofibromatosis Type 1-Associated Plexiform Neurofibromas

🎯 check AZD6244 (Selumetinib) product page

AZD6244 is a potent ATP-uncompetitive MEK1/2 inhibitor. It affects MAPK/ERK signaling by blocking ERK, inhibiting tumor growth.

Primary Applications and Mechanism of Action