|
2XSB
|
10 µM
|
High-content drug sensitivity assay using cellular confluence, AUC dose-response curves
|
Download PDF
|
|
ST88-14
|
4.2 µM
|
High-content drug sensitivity assay using cellular confluence, AUC dose-response curves
|
Download PDF
|
|
NMS-2PC
|
8.2 µM
|
High-content drug sensitivity assay using cellular confluence, AUC dose-response curves
|
Download PDF
|
|
NMS-2
|
1.7 µM
|
High-content drug sensitivity assay using cellular confluence, AUC dose-response curves
|
Download PDF
|
|
control Schwann cells
|
14.36±0.95
|
Cell Counting Kit-8 assay; determined from inhibition curves (log inhibitor concentration vs percentage of inhibition)
|
Download PDF
|
|
shNF1 Schwann cells
|
24.83±0.98
|
Cell Counting Kit-8 assay; determined from inhibition curves (log inhibitor concentration vs percentage of inhibition)
|
Download PDF
|
|
ipNF95.11bC
|
36.47 μM
|
CCK-8 assay, calculated via Graphpad prism 8.0 software
|
Download PDF
|
|
ipNF95.6
|
34.62 μM
|
CCK-8 assay, calculated via Graphpad prism 8.0 software
|
Download PDF
|
|
shNf1-SW10 cells
|
32.52 μM
|
CCK-8 assay, calculated via Graphpad prism 8.0 software
|
Download PDF
|
|
T24
|
85.54 ± 15.50 μM
|
CCK-8 assay
|
PMC12046919
|
|
UMUC3
|
92.0 ± 10.12 μM
|
CCK-8 assay
|
PMC12046919
|
|
HepG2
|
0.33 µM
|
Alamar blue assay
|
PMC8141275
|
|
Hep3B
|
1.2 µM
|
Alamar blue assay
|
PMC8141275
|
|
HFF-1
|
1.3 µM
|
Alamar blue assay
|
PMC8141275
|
|
A375
|
67.52 ± 0.07 nM
|
MTS assay
|
Download PDF
|
|
COLO 205
|
54.33 ± 2.21 nM
|
MTS assay
|
Download PDF
|
|
Colo-829
|
301.10 ± 88.79 nM
|
MTS assay
|
Download PDF
|
|
HT-29
|
175.28 ± 19.26 nM
|
MTS assay
|
Download PDF
|
|
Calu-6
|
2305.07 ± 203.56 nM
|
MTS assay
|
Download PDF
|
|
A549
|
5732.45 ± 1028.89 nM
|
MTS assay
|
Download PDF
|
|
HL-60
|
35.26 ± 20.92 nM
|
MTS assay
|
Download PDF
|
|
H1975
|
>50,000 nM
|
MTS assay
|
Download PDF
|
|
MRC-5
|
>50,000 nM
|
MTS assay
|
Download PDF
|
|
HCT116 wildtype
|
7.4 µM
|
resazurin assay
|
Download PDF
|
|
CHL-1
|
1.4 nM (control), 9.1 nM (siDUSP4_1), 6.9 nM (siDUSP4_2)
|
Clonogenic survival assay
|
Download PDF
|
|
SK-MEL-23
|
0.32 nM (control), 0.56 nM (siDUSP4_1), 0.68 nM (siDUSP4_2)
|
Clonogenic survival assay
|
Download PDF
|
|
A375
|
2.2 µM
|
Toluidine blue staining and quantification of optical density at 555 nm (OD 555) of solubilized dye, analyzed with a nonlinear regression curve fit model.
|
PMC3536641
|
|
A375-pLKO
|
1.69 µM
|
Toluidine blue staining and quantification of optical density at 555 nm (OD 555) of solubilized dye, analyzed with a nonlinear regression curve fit model.
|
PMC3536641
|
|
A375-S2C4
|
26.62 nM
|
Toluidine blue staining and quantification of optical density at 555 nm (OD 555) of solubilized dye, analyzed with a nonlinear regression curve fit model.
|
PMC3536641
|
|
A375-S2C14
|
23.3 nM
|
Toluidine blue staining and quantification of optical density at 555 nm (OD 555) of solubilized dye, analyzed with a nonlinear regression curve fit model.
|
PMC3536641
|
|
SW480
|
4.32 µM
|
CellTiter Glo assay
|
PMC7418728
|
|
NK-92
|
>25 µM
|
CellTiter Glo assay
|
PMC7418728
|
|
49 melanoma cell lines
|
Responsive: < 0.05 μM; Resistant: ≥ 0.2 μM
|
MTT assay
|
Download PDF
|
|
Human PBMCs
|
5.8 nM
|
IL-2 release measured by immuno-assay (DELFIA using human IL-2 ELISA kit)
|
Download PDF
|
|
HCC1937
|
15.65
|
MTT assay
|
Download PDF
|
|
MDA-MB-231
|
12.94
|
MTT assay
|
Download PDF
|
|
MYL-R cells
|
5 mM
|
48 hour MTS assay
|
Download PDF
|
|
MYL-R cells
|
5 mM
|
48 hour MTS assay
|
Download PDF
|
|
NCI-H1993
|
5.6 μM
|
MTT assay
|
Download PDF
|
|
NCI-H1975
|
37.5 μM
|
MTT assay
|
Download PDF
|
|
NCI-H460
|
26.8 μM
|
MTT assay
|
Download PDF
|
|
HCT116
|
312 nM
|
Sulforhodamine B (SRB) assay
|
Download PDF
|
|
DLD1
|
4973 nM
|
Sulforhodamine B (SRB) assay
|
Download PDF
|
|
HT29
|
29 nM
|
Sulforhodamine B (SRB) assay
|
Download PDF
|
|
SF-295
|
7.383 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
SNB-19
|
15.13 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
LOX-IMVI
|
6.032 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
K-562
|
82.07 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
CCRF-CEM
|
125.9 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
HL-60
|
20.95 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
UACC-62
|
0.4870 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
UACC-257
|
0.4650 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
M14
|
0.06103 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
SK-MEL-28
|
0.2098 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
COLO-205
|
0.02923 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
SW-620
|
0.05538 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
mucin-IHCCA
|
18.7 ± 6.1 μM
|
MTS assay
|
Download PDF
|
|
mixed-IHCCA
|
140.4 ± 36.2 μM
|
MTS assay
|
Download PDF
|
|
GLC82
|
>10 mM
|
MTT assay
|
PMC3349172
|
|
H460
|
>10 mM
|
MTT assay
|
PMC3349172
|
|
A549
|
5 mM
|
MTT assay
|
PMC3349172
|
|
H1299
|
<0.01 mM
|
MTT assay
|
PMC3349172
|
|
Calu3
|
<0.01 mM
|
MTT assay
|
PMC3349172
|
|
GEO
|
1 mM
|
MTT assay
|
PMC3349172
|
|
HCT15
|
>10 mM
|
MTT assay
|
PMC3349172
|
|
HCT116
|
0.01 mM
|
MTT assay
|
PMC3349172
|
|
SW480
|
1 mM
|
MTT assay
|
PMC3349172
|
|
SW620
|
0.01 mM
|
MTT assay
|
PMC3349172
|
|
LS174T
|
10 mM
|
MTT assay
|
PMC3349172
|
|
H358
|
>1 μM
|
BrdUrd incorporation assay
|
Download PDF
|
|
Calu-3
|
0.5 μM
|
BrdUrd incorporation assay
|
Download PDF
|
|
H1299
|
0.01 μM
|
BrdUrd incorporation assay
|
Download PDF
|
|
H1975
|
>5 μM
|
BrdUrd incorporation assay
|
Download PDF
|
|
HepG2
|
27.8 nM
|
BrdU incorporation
|
PMC4622849
|
|
Huh7
|
3031 nM
|
BrdU incorporation
|
PMC4622849
|
|
Hep3B
|
> 10 µM
|
BrdU incorporation
|
PMC4622849
|
|
2XSB
|
10 µM
|
High-content drug sensitivity assay using cellular confluence, AUC dose-response curves
|
Download PDF
|
|
ST88-14
|
4.2 µM
|
High-content drug sensitivity assay using cellular confluence, AUC dose-response curves
|
Download PDF
|
|
NMS-2PC
|
8.2 µM
|
High-content drug sensitivity assay using cellular confluence, AUC dose-response curves
|
Download PDF
|
|
NMS-2
|
1.7 µM
|
High-content drug sensitivity assay using cellular confluence, AUC dose-response curves
|
Download PDF
|
|
control Schwann cells
|
14.36±0.95
|
Cell Counting Kit-8 assay; determined from inhibition curves (log inhibitor concentration vs percentage of inhibition)
|
Download PDF
|
|
shNF1 Schwann cells
|
24.83±0.98
|
Cell Counting Kit-8 assay; determined from inhibition curves (log inhibitor concentration vs percentage of inhibition)
|
Download PDF
|
|
ipNF95.11bC
|
36.47 μM
|
CCK-8 assay, calculated via Graphpad prism 8.0 software
|
Download PDF
|
|
ipNF95.6
|
34.62 μM
|
CCK-8 assay, calculated via Graphpad prism 8.0 software
|
Download PDF
|
|
shNf1-SW10 cells
|
32.52 μM
|
CCK-8 assay, calculated via Graphpad prism 8.0 software
|
Download PDF
|
|
T24
|
85.54 ± 15.50 μM
|
CCK-8 assay
|
PMC12046919
|
|
UMUC3
|
92.0 ± 10.12 μM
|
CCK-8 assay
|
PMC12046919
|
|
HepG2
|
0.33 µM
|
Alamar blue assay
|
PMC8141275
|
|
Hep3B
|
1.2 µM
|
Alamar blue assay
|
PMC8141275
|
|
HFF-1
|
1.3 µM
|
Alamar blue assay
|
PMC8141275
|
|
A375
|
67.52 ± 0.07 nM
|
MTS assay
|
Download PDF
|
|
COLO 205
|
54.33 ± 2.21 nM
|
MTS assay
|
Download PDF
|
|
Colo-829
|
301.10 ± 88.79 nM
|
MTS assay
|
Download PDF
|
|
HT-29
|
175.28 ± 19.26 nM
|
MTS assay
|
Download PDF
|
|
Calu-6
|
2305.07 ± 203.56 nM
|
MTS assay
|
Download PDF
|
|
A549
|
5732.45 ± 1028.89 nM
|
MTS assay
|
Download PDF
|
|
HL-60
|
35.26 ± 20.92 nM
|
MTS assay
|
Download PDF
|
|
H1975
|
>50,000 nM
|
MTS assay
|
Download PDF
|
|
MRC-5
|
>50,000 nM
|
MTS assay
|
Download PDF
|
|
HCT116 wildtype
|
7.4 µM
|
resazurin assay
|
Download PDF
|
|
CHL-1
|
1.4 nM (control), 9.1 nM (siDUSP4_1), 6.9 nM (siDUSP4_2)
|
Clonogenic survival assay
|
Download PDF
|
|
SK-MEL-23
|
0.32 nM (control), 0.56 nM (siDUSP4_1), 0.68 nM (siDUSP4_2)
|
Clonogenic survival assay
|
Download PDF
|
|
A375
|
2.2 µM
|
Toluidine blue staining and quantification of optical density at 555 nm (OD 555) of solubilized dye, analyzed with a nonlinear regression curve fit model.
|
PMC3536641
|
|
A375-pLKO
|
1.69 µM
|
Toluidine blue staining and quantification of optical density at 555 nm (OD 555) of solubilized dye, analyzed with a nonlinear regression curve fit model.
|
PMC3536641
|
|
A375-S2C4
|
26.62 nM
|
Toluidine blue staining and quantification of optical density at 555 nm (OD 555) of solubilized dye, analyzed with a nonlinear regression curve fit model.
|
PMC3536641
|
|
A375-S2C14
|
23.3 nM
|
Toluidine blue staining and quantification of optical density at 555 nm (OD 555) of solubilized dye, analyzed with a nonlinear regression curve fit model.
|
PMC3536641
|
|
SW480
|
4.32 µM
|
CellTiter Glo assay
|
PMC7418728
|
|
NK-92
|
>25 µM
|
CellTiter Glo assay
|
PMC7418728
|
|
49 melanoma cell lines
|
Responsive: < 0.05 μM; Resistant: ≥ 0.2 μM
|
MTT assay
|
Download PDF
|
|
Human PBMCs
|
5.8 nM
|
IL-2 release measured by immuno-assay (DELFIA using human IL-2 ELISA kit)
|
Download PDF
|
|
HCC1937
|
15.65
|
MTT assay
|
Download PDF
|
|
MDA-MB-231
|
12.94
|
MTT assay
|
Download PDF
|
|
MYL-R cells
|
5 mM
|
48 hour MTS assay
|
Download PDF
|
|
MYL-R cells
|
5 mM
|
48 hour MTS assay
|
Download PDF
|
|
NCI-H1993
|
5.6 μM
|
MTT assay
|
Download PDF
|
|
NCI-H1975
|
37.5 μM
|
MTT assay
|
Download PDF
|
|
NCI-H460
|
26.8 μM
|
MTT assay
|
Download PDF
|
|
HCT116
|
312 nM
|
Sulforhodamine B (SRB) assay
|
Download PDF
|
|
DLD1
|
4973 nM
|
Sulforhodamine B (SRB) assay
|
Download PDF
|
|
HT29
|
29 nM
|
Sulforhodamine B (SRB) assay
|
Download PDF
|
|
SF-295
|
7.383 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
SNB-19
|
15.13 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
LOX-IMVI
|
6.032 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
K-562
|
82.07 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
CCRF-CEM
|
125.9 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
HL-60
|
20.95 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
UACC-62
|
0.4870 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
UACC-257
|
0.4650 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
M14
|
0.06103 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
SK-MEL-28
|
0.2098 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
COLO-205
|
0.02923 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
SW-620
|
0.05538 μM
|
system and Cell counting kit -SK proliferation assay
|
Download PDF
|
|
mucin-IHCCA
|
18.7 ± 6.1 μM
|
MTS assay
|
Download PDF
|
|
mixed-IHCCA
|
140.4 ± 36.2 μM
|
MTS assay
|
Download PDF
|
|
GLC82
|
>10 mM
|
MTT assay
|
PMC3349172
|
|
H460
|
>10 mM
|
MTT assay
|
PMC3349172
|
|
A549
|
5 mM
|
MTT assay
|
PMC3349172
|
|
H1299
|
<0.01 mM
|
MTT assay
|
PMC3349172
|
|
Calu3
|
<0.01 mM
|
MTT assay
|
PMC3349172
|
|
GEO
|
1 mM
|
MTT assay
|
PMC3349172
|
|
HCT15
|
>10 mM
|
MTT assay
|
PMC3349172
|
|
HCT116
|
0.01 mM
|
MTT assay
|
PMC3349172
|
|
SW480
|
1 mM
|
MTT assay
|
PMC3349172
|
|
SW620
|
0.01 mM
|
MTT assay
|
PMC3349172
|
|
LS174T
|
10 mM
|
MTT assay
|
PMC3349172
|
|
H358
|
>1 μM
|
BrdUrd incorporation assay
|
Download PDF
|
|
Calu-3
|
0.5 μM
|
BrdUrd incorporation assay
|
Download PDF
|
|
H1299
|
0.01 μM
|
BrdUrd incorporation assay
|
Download PDF
|
|
H1975
|
>5 μM
|
BrdUrd incorporation assay
|
Download PDF
|
|
HepG2
|
27.8 nM
|
BrdU incorporation
|
PMC4622849
|
|
Huh7
|
3031 nM
|
BrdU incorporation
|
PMC4622849
|
|
Hep3B
|
> 10 µM
|
BrdU incorporation
|
PMC4622849
|
