AZD6244 is a potent ATP-uncompetitive MEK1/2 inhibitor. It affects MAPK/ERK signaling by blocking ERK, inhibiting tumor growth.
Comprehensive IC50 Values for AZD6244 (Selumetinib) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
AZD6244 is a potent ATP-uncompetitive MEK1/2 inhibitor. It affects MAPK/ERK signaling by blocking ERK, inhibiting tumor growth.