2D Structure
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2D chemical structural formula diagram.
3D Structure
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This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
Selinexor (KPT-330)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide | |
|---|---|---|
| CAS Number | 1393477-72-9 | |
| Molecular Formula |
C17H11F6N7O |
|
| Molecular Weight (MW) | 443.31 | |
| SMILES | C1=CN=C(C=N1)NNC(=O)C=CN2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F | |
| InChIKey | DEVSOMFAQLZNKR-RJRFIUFISA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
89 mg/mL
(200.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 89 mg/mL |
| Water | Insoluble |
| DMSO |
89 mg/mL
(200.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 22 mg/mL |
| Water | Insoluble |
| DMSO |
89 mg/mL
(200.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 89 mg/mL |
| Water | Insoluble |
| DMSO |
89 mg/mL
(200.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 89 mg/mL |
| Water | Insoluble |
| DMSO |
88 mg/mL
(198.5 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 88 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Selinexor (KPT-330) Mechanism of Action: XPO1 Inhibition in Plasma Cell Research
- Selinexor (KPT-330) Clinical Trials
- Selinexor (KPT-330) Working Concentration | Cell Culture | Treatment
- Selinexor (KPT-330) Solubility in DMSO
- Selinexor (KPT-330) Stock Solution
- Selinexor (KPT-330) Storage
- Selinexor (KPT-330) Stability
- Selinexor (KPT-330) Combination Database
- Selinexor (KPT-330) Molecular Weight
- Selinexor (KPT-330) SMILES
- Selinexor (KPT-330) CAS Number
- Selinexor (KPT-330) IC50 for Cell-based and Cell-free Assays
- Selinexor (KPT-330) Sigma (AMBH2D6FBC43)? Try a better option.
- Selinexor (KPT-330) Tocris (7760)? Try a better option.
- Selinexor (KPT-330) MedChemExpress (HY-17536)? Try a better option.
- Selinexor (KPT-330) Cayman (39562)? Try a better option.
- Selinexor (KPT-330) Abmole (M3152)? Try a better option.
- Selinexor (KPT-330) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.