Molecular Weight: 372.46 g/mol

Zotiraciclib Chemical Structure
Chemical Structure
Check the Zotiraciclib product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 15 mg/mL (40.27 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Chemical Information

IUPAC Name 14-methyl-20-oxa-5,7,14,27-tetrazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2(27),3,5,8,10,12(26),16,21,23-decaene
CAS Number 937270-47-8
Molecular Formula

C23H24N4O
Molecular Weight (MW) 372.46
SMILES CN1C/C=C/CCOC2=CC(=CC=C2)C3=CC=NC(=NC4=CC=CC(=C4)C1)N3
InChIKey VXBAJLGYBMTJCY-UHFFFAOYSA-N

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Note: Technical data last updated: Sep 1, 2026.