SMILES:
CC1COCCN1C2=CC(=O)N3CCC(N(C3=N2)CC4=CC(=CN=C4)Cl)C(F)(F)F
Chemical Structure
Check the
SAR405
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (8S)-9-[(5-chloro-3-pyridinyl)methyl]-2-[(3R)-3-methylmorpholin-4-yl]-8-(trifluoromethyl)-7,8-dihydro-6H-pyrimido[1,2-a]pyrimidin-4-one | |
|---|---|---|
| CAS Number | 1523406-39-4 | |
| Molecular Formula |
C19H21ClF3N5O2 |
|
| Molecular Weight (MW) | 443.85 | |
| SMILES | CC1COCCN1C2=CC(=O)N3CCC(N(C3=N2)CC4=CC(=CN=C4)Cl)C(F)(F)F | |
| InChIKey | SPDQRCUBFSRAFI-DOMZBBRYSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
89 mg/mL
(200.51 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 89 mg/mL |
| Water | Insoluble |
| DMSO |
88 mg/mL
(198.26 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 88 mg/mL |
| Water | Insoluble |
| DMSO |
88 mg/mL
(198.26 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 88 mg/mL |
| Water | Insoluble |
| DMSO |
89 mg/mL
(200.51 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 29 mg/mL |
| Water | Insoluble |
| DMSO |
89 mg/mL
(200.51 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 89 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- SAR405 Mechanism of Action: VPS34 Inhibition in Tumor Cell Research
- SAR405 Working Concentration | Cell Culture | Treatment
- SAR405 Solubility in DMSO
- SAR405 Stock Solution
- SAR405 Storage
- SAR405 Stability
- SAR405 Combination Database
- SAR405 Molecular Weight
- SAR405 CAS Number
- SAR405 Chemical Structure (2D and 3D)
- SAR405 IC50 for Cell-based and Cell-free Assays
- SAR405 Sigma (AMBH303C4EB3)? Try a better option.
- SAR405 APExBIO (A8883)? Try a better option.
- SAR405 MedChemExpress (HY-12481)? Try a better option.
- SAR405 Cayman (16979)? Try a better option.
- SAR405 SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.