SAR405: Mechanism of Action

SAR405 MOA:Targeting VPS34/Autophagy Pathway for Oncology Research

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SAR405 is a selective VPS34 inhibitor. It affects autophagy, NF-κB, and STING signaling pathways by blocking autophagic flux, effectively inhibiting cancer cell proliferation and migration, and promoting immune cell activation.

Primary Applications and Mechanism of Action