Home Biosimilar Antibodies Immunology & Inflammation Immunology & Inflammation related inhibitor Sabatolimab (anti-TIM-3)
For research use only. Not for use in humans.

Sabatolimab (anti-TIM-3)

Synonyms: MBG453, NVP-MBG453

Sabatolimab (anti-TIM-3) (MBG453, NVP-MBG453) is a high-affinity, humanized IgG4 antibody targeting TIM-3 on the surface of T-cells.

Sabatolimab (anti-TIM-3)

Click to purchase the isotype control of Sabatolimab (anti-TIM-3)

3 Citations

The Nobel Prize

17 Nobel Prize winners have used Selleck products

Shimon Sakaguchi

Nature Communications 2025,16, Article number:1325

David Baker

Dev Cell 2023, 58(20):2163-2180.e9.

David Julius

Cell 2017, 185-198.e16

Michael Houghton

Cell Chem Biol, 2020, 27(7):780-792.e5

Charles M. Rice

Cell 2018, 172(3):423-438.e25

Quality Control

Batch: Purity: 99.44% Protein concentration: 6.3mg/ml Endotoxin Level: ＜1EU/mg
99.44

Specificity

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description

Sabatolimab (anti-TIM-3) (MBG453, NVP-MBG453) is a high-affinity, humanized IgG4 antibody targeting TIM-3 on the surface of T-cells.
References

Product Details

CAS No. 2252262-24-9
Molecular Weight 145 KD
Isotype Human IgG4, κ
Application Sabatolimab (anti-TIM-3)
Source CHO cells
Purification Protein G
Sterility 0.2 μM filtered
Formulation PBS Buffer, PH 7.4
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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