Romidepsin (FK228) is a potent, selective class I HDAC inhibitor. It affects PI3K/AKT, MAPK, and NF-κB signaling pathways, and by increasing histone acetylation and altering gene expression, it inhibits tumor cell proliferation and promotes apoptosis.
Romidepsin (FK228) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Romidepsin (FK228) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.