Cell-free Assays (IC50/Ki) for RO4929097 (RG-4733)
| Key Target | IC50 (Cell-free) | Description | Reference |
|---|---|---|---|
| No published data available. | |||
Cell-based Assay (IC50) for RO4929097 (RG-4733)
| Cell Type | IC50 (Cell-based) | Description | Reference |
|---|---|---|---|
| A375 | 10.8 mM | Cell viability signal assessed with 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium colorimetric cell viability assay (CellTiter 96 AQueous One; [Vendor], Madison, WI). IC50 was obtained using nonlinear regression | PMC7940786 |
| SKMEL28 | 46.97 mM | Cell viability signal assessed with 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium colorimetric cell viability assay (CellTiter 96 AQueous One; [Vendor], Madison, WI). IC50 was obtained using nonlinear regression | PMC7940786 |
Check the
RO4929097 (RG-4733)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
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- RO4929097 (RG-4733) Mechanism of Action: Gamma-secretase Inhibition in Tumor Cell Research
- RO4929097 (RG-4733) Clinical Trials
- RO4929097 (RG-4733) Working Concentration | Cell Culture | Treatment
- RO4929097 (RG-4733) Solubility in DMSO
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- RO4929097 (RG-4733) Combination Database
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- RO4929097 (RG-4733) SDS｜MSDS