RO4929097 is a potent γ-secretase inhibitor. It affects Notch signaling by blocking cleavage, inhibiting EMT and tumor growth.
Comprehensive IC50 Values for RO4929097 (RG-4733) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
RO4929097 is a potent γ-secretase inhibitor. It affects Notch signaling by blocking cleavage, inhibiting EMT and tumor growth.