2D Structure
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2D chemical structural formula diagram.
3D Structure
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This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
RO4929097 (RG-4733)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2,2-dimethyl-N-[(7S)-6-oxo-5,7-dihydrobenzo[d][1]benzazepin-7-yl]-N'-(2,2,3,3,3-pentafluoropropyl)propanediamide | |
|---|---|---|
| CAS Number | 847925-91-1 | |
| Molecular Formula |
C22H20F5N3O3 |
|
| Molecular Weight (MW) | 469.4 | |
| SMILES | CC(C)(C(=O)NCC(C(F)(F)F)(F)F)C(=O)NC1C2=CC=CC=C2C3=CC=CC=C3NC1=O | |
| InChIKey | OJPLJFIFUQPSJR-INIZCTEOSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
94 mg/mL
(200.25 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 50 mg/mL |
| Water | Insoluble |
| DMSO |
94 mg/mL
(200.25 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 43 mg/mL |
| Water | Insoluble |
| DMSO |
93 mg/mL
(198.12 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 93 mg/mL |
| Water | Insoluble |
| DMSO |
93 mg/mL
(198.12 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 78 mg/mL |
| Water | Insoluble |
| DMSO |
93 mg/mL
(198.12 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 93 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- RO4929097 (RG-4733) Mechanism of Action: Gamma-secretase Inhibition in Tumor Cell Research
- RO4929097 (RG-4733) Clinical Trials
- RO4929097 (RG-4733): Selectivity & Specificity
- RO4929097 (RG-4733) Working Concentration | Cell Culture | Treatment
- RO4929097 (RG-4733) Solubility in DMSO
- RO4929097 (RG-4733) Stock Solution
- RO4929097 (RG-4733) Storage
- RO4929097 (RG-4733) Stability
- RO4929097 (RG-4733) Combination Database
- RO4929097 (RG-4733) Molecular Weight
- RO4929097 (RG-4733) SMILES
- RO4929097 (RG-4733) CAS Number
- RO4929097 (RG-4733) IC50 for Cell-based and Cell-free Assays
- RO4929097 (RG-4733) APExBIO (A4005)? Try a better option.
- RO4929097 (RG-4733) Cayman (19996)? Try a better option.
- RO4929097 (RG-4733) MedChemExpress (HY-11102)? Try a better option.
- RO4929097 (RG-4733) Sigma (SML4098)? Try a better option.
- RO4929097 (RG-4733) SDS|MSDS
Note: Technical data last updated: Sep 1, 2026.