CAS No. 117-39-5
Batch:
Purity:99.01
Chemical Structure
Check the
Quercetin (Sophoretin)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one | |
|---|---|---|
| CAS Number | 117-39-5 | |
| Molecular Formula |
C15H10O7 |
|
| Molecular Weight (MW) | 302.24 | |
| InChIKey | REFJWTPEDVJJIY-UHFFFAOYSA-N |
Biological Activity
Quercetin is a natural flavonoid that acts as a PI3K inhibitor with an IC50 ofand a stimulator of recombinant SIRT1 deacetylase activity. It regulates downstream cellular signaling through pathways such as PI3K/AKT and NF-kB, thereby suppressing pro-inflammatory mediator production while promoting apoptosis, protective autophagy, and mitophagy in various cell types. [1][2]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
60 mg/mL
(198.51 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
61 mg/mL
(201.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 20 mg/mL |
| Water | Insoluble |
| DMSO |
60 mg/mL
(198.51 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 8 mg/mL |
| Water | Insoluble |
| DMSO |
60 mg/mL
(198.51 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 60 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer longer shelf life compared to stock solutions.
Looking for a specific aliquot size? Contact your local sales representative or orders@selleckchem.com.
Reference
Jump to
- Quercetin (Sophoretin) Mechanism of Action: PI3K Inhibition in Cancer Cell Research
- Quercetin (Sophoretin) Clinical Trials
- Quercetin (Sophoretin) Working Concentration | Cell Culture | Treatment
- Quercetin (Sophoretin) Solubility in DMSO
- Quercetin (Sophoretin) Stock Solution
- Quercetin (Sophoretin) Storage
- Quercetin (Sophoretin) Stability
- Quercetin (Sophoretin) Combination Database
- Quercetin (Sophoretin) Molecular Weight
- Quercetin (Sophoretin) Chemical Structure (2D and 3D)
- Quercetin (Sophoretin) IC50 for Cell-based and Cell-free Assays
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Note: Technical data last updated: Sep 1, 2026.