CAS No. 853645-22-4
Batch:
Purity:99.05
Chemical Structure
Check the
Pyridoxal 5′-phosphate hydrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (4-formyl-5-hydroxy-6-methyl-3-pyridinyl)methyl dihydrogen phosphate | |
|---|---|---|
| CAS Number | 853645-22-4 | |
| Molecular Formula |
C8H10NO6P.xH2O |
|
| Molecular Weight (MW) | 247.14 | |
| SMILES | CC1=NC=C(C(=C1O)C=O)COP(=O)(O)O | |
| InChIKey | NGVDGCNFYWLIFO-UHFFFAOYSA-N |
Pyridoxal 5′-phosphate hydrate is an active vitamin B6 coenzyme and an inhibitor of viral DNA polymerases. It serves as a vital cofactor across enzymatic transamination and decarboxylation reactions within cellular metabolic pathways. Additionally, interaction with NEIL2 abolishes its ability to bind damaged DNA, downregulating base excision repair mechanisms and modulating nucleic acid biosynthesis phenotypes.
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
49 mg/mL
(198.26 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 6 mg/mL |
| Ethanol | Insoluble |
| DMSO |
10 mg/mL
(40.46 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Pyridoxal 5′-phosphate hydrate Clinical Trials
- Pyridoxal 5′-phosphate hydrate Solubility in DMSO
- Pyridoxal 5′-phosphate hydrate Stock Solution
- Pyridoxal 5′-phosphate hydrate Storage
- Pyridoxal 5′-phosphate hydrate Stability
- Pyridoxal 5′-phosphate hydrate Molecular Weight
- Pyridoxal 5′-phosphate hydrate SMILES
- Pyridoxal 5′-phosphate hydrate Chemical Structure (2D and 3D)
- Pyridoxal 5′-phosphate hydrate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.