Stability

PX-478 Dihydrochloride is sensitive to moisture and oxidation. Store tightly sealed and minimize exposure to air and moisture. Prepare solutions fresh prior to use; stock-solution storage is not recommended.

Storage

Form Storage Temp Shelf Life
3 years -20°C powder (seal)
In Solvent prepare solutions fresh‑for‑use
Check the PX-478 Dihydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 79 mg/mL (200.44 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 79 mg/mL
Ethanol 79 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.