CAS No. 66-97-7
Batch:
Purity:99.92
Chemical Structure
Check the
Psoralen
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | furo[3,2-g]chromen-7-one | |
|---|---|---|
| CAS Number | 66-97-7 | |
| Molecular Formula |
C11H6O3 |
|
| Molecular Weight (MW) | 186.16 | |
| SMILES | C1=CC(=O)OC2=CC3=C(C=CO3)C=C21 | |
| InChIKey | ZCCUUQDIBDJBTK-UHFFFAOYSA-N |
Psoralen is a naturally occurring furocoumarin that acts as a DNA-intercalating agent. Upon intercalating into the DNA double helix, it forms photoinduced covalent adducts and interstrand cross-links with pyrimidine bases. These DNA structural modifications disrupt nucleic acid template function, resulting in the inhibition of DNA replication, transcription, and cellular proliferation across diverse biological systems.
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
37 mg/mL
(198.75 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
37 mg/mL
(198.75 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.