Picropodophyllin (AXL1717) is a potent, specific small-molecule IGF-1R inhibitor. It affects IGF-1R/Akt, PI3K/mTOR, and Hippo-YAP signaling pathways by blocking IGF-1R tyrosine phosphorylation and downregulating downstream kinases, effectively inhibiting cancer cell proliferation, migration, and promoting apoptosis.
Picropodophyllin (AXL1717) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Picropodophyllin (AXL1717) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
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- Picropodophyllin (AXL1717) Mechanism of Action: IGF-1R Inhibition in Non-Small Cell Lung Cancer Cell Research
- Picropodophyllin (AXL1717) Clinical Trials
- Picropodophyllin (AXL1717) Working Concentration | Cell Culture | Treatment
- Picropodophyllin (AXL1717) Solubility in DMSO
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- Picropodophyllin (AXL1717) Combination Database
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- Picropodophyllin (AXL1717) Chemical Structure (2D and 3D)
- Picropodophyllin (AXL1717) Cayman (17329)? Try a better option.
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- Picropodophyllin (AXL1717) SDS｜MSDS