Molecular Weight: 396.44 g/mol

PD-166866 Chemical Structure
Chemical Structure
Check the PD-166866 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

How to Prepare Stock Solution?

Concentration Volume Mass
1 mg 5 mg 10 mg
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 40 mg/mL (100.89 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 4 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Aliquotting Service

Free Aliquotting Service

Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.

Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.

Chemical Information

IUPAC Name 1-[2-amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
CAS Number 192705-79-6
Molecular Formula

C20H24N6O3
Molecular Weight (MW) 396.44
SMILES CC(C)(C)NC(=O)NC1=C(C=C2C=NC(=NC2=N1)N)C3=CC(=CC(=C3)OC)OC
InChIKey NHJSWORVNIOXIT-UHFFFAOYSA-N

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Note: Technical data last updated: Sep 1, 2026.