Synonyms: BA3021
Ozuriftamab (Anti-ROR2) is a naked human IgG1 kappa antibody targeting receptor tyrosine kinase-like orphan receptor 2 ROR.It has antineoplastic activity and can be used in research of head and neck squamous cell cancer (HNSCC)
Shimon Sakaguchi
Nature Communications 2025,16, Article number:1325
David Baker
Dev Cell 2023, 58(20):2163-2180.e9.
David Julius
Cell 2017, 185-198.e16
Michael Houghton
Cell Chem Biol, 2020, 27(7):780-792.e5
Charles M. Rice
Cell 2018, 172(3):423-438.e25
| Featured Inhibitors | Y-27632 Dihydrochloride SB431542 CHIR-99021 (Laduviglusib) RMC-7977 RMC-6236 (Daraxonrasib) MRTX1133 MG132 Z-VAD-FMK VT3989 IAG933 |
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| Description |
Ozuriftamab (Anti-ROR2) is a naked human IgG1 kappa antibody targeting receptor tyrosine kinase-like orphan receptor 2 ROR.It has antineoplastic activity and can be used in research of head and neck squamous cell cancer (HNSCC)
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References |
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| CAS No. | 2460399-44-2 |
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| Isotype | Human IgG1 |
| Source | CHO |
| Formulation | 100 mM Pro-Ac, 20mM Arg, pH5.0 |
| Storage (From the date of receipt) |
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)
| NCT Number | Recruitment | interventions | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|---|
| NCT05271604 | COMPLETED | Head and Neck Cancer; Squamous Cell Carcinoma of Head and Neck; Recurrent Squamous Cell Carcinoma of the Head and Neck; Metastatic Cancer; Metastatic Squamous Cell Carcinoma of the Head and Neck | BioAtla, Inc. | 2022-12-13 | PHASE2 |
(data from https://clinicaltrials.gov, updated on 2025-09-26)
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